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    Concordance Between Tissue ALK Detection by Immunohistochemistry and Plasma ALK Detection by Next-Generation Sequencing in the Randomized Phase 3 ALEX Study in Patients With Treatment-Naive Advanced ALK-Positive NSCLC by Johannes Noé, PhD, Walter Bordogna, PhD, Venice Archer, MD, Vlatka Smoljanovic, MD, Magalie Hilton, MSc, Ryan Woodhouse, BSc, Simonetta Mocci, MD, PhD, Shirish M. Gadgeel, MD

    Published 2022-07-01
    “…To understand the relationship between tissue-based versus blood-based testing, we retrospectively investigated concordance between VENTANA ALK (D5F3) CDx immunohistochemistry and the FoundationACT (FACT; Foundation Medicine, Inc.) plasma assay, and compared clinical efficacy between phase 3 ALEX study subpopulations. Methods: Patients with advanced ALK-positive (by immunohistochemistry) NSCLC were randomized 1:1 to alectinib 600 mg or crizotinib 250 mg, twice daily. …”
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    The murder book / by Kellerman, Jonathan, author

    Published 2002
    Subjects: “…Delaware, Alex (Fictitious character)…”
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