Significance of Astragaloside IV from the Roots of <i>Astragalus mongholicus</i> as an Acetylcholinesterase Inhibitor—From the Computational and Biomimetic Analyses to the In Vitro... by Katarzyna Stępnik, Wirginia Kukula-Koch, Wojciech Plazinski, Kinga Gawel, Katarzyna Gaweł-Bęben, Daariimaa Khurelbat, Anna Boguszewska-Czubara

“…Moreover, molecular dynamics simulations were carried outto assess the affinity of the tested compounds for POPC and POPG-containing lipid bilayers, which in this case are the models of the blood-brain barrier (BBB). All determined free energy profiles confirmed that astragalosides exhibit great affinity for the lipid bilayer. …”
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Staged Hindfoot Fusion for Osteomyelitis of the Distal Tibia and Talus by Peter R. Wasky MD, Nihar S. Shah MD, Augusto Roca, Richard T. Laughlin MD

“…All are able to walk unaided. And thus far, all are free of active infection. Secondary procedures are described. …”
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The use of Montgomery salivary bypass tubes and pharyngocutaneous fistula following salvage laryngectomy by Courtney B. Shires, Mackenzie Latour, Merry Sebelik, Karuna Dewan

“…Methods We conducted a retrospective cohort study of patients undergoing STL with placement of Montgomery salivary bypass tube (MSBT)™ for at least 2 weeks duration between 2013 and 2017 at a single institution. Our patients all underwent free flap reconstruction. Our primary outcome of interest was development of PCF. …”
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Reduction in the Brining Time in Parmigiano Reggiano Cheese Production Minimally Affects Proteolysis, with No Effect on Sensory Properties by Cecilia Loffi, Elena Bortolazzo, Anna Garavaldi, Valeria Musi, Paolo Reverberi, Gianni Galaverna, Stefano Sforza, Tullia Tedeschi

“…A full characterization of free amino acids and peptides was performed by LC-MS on all samples. Free amino acids and peptides, as expected, increased with ripening, due to proteolysis, with samples having low salt content showing a slightly faster increase when compared to standard ones, hinting to a slightly accelerated proteolytic process. …”
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Diversity and Content of Carotenoids and Other Pigments in the Transition from the Green to the Red Stage of <i>Haematococcus pluvialis</i> Microalgae Identified by HPLC-DAD and LC... by Veno Jaša Grujić, Biljana Todorović, Roman Kranvogl, Terezija Ciringer, Jana Ambrožič-Dolinšek

“…They represented 82% of all pigments, and their content was about 5 times higher than both, diesters (5.91 mg g⁻¹ DW or 12% of all) and free carotenoids (2.4 mg g⁻¹ DW or 6% of all). …”
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Lost and Found: Piwi and Argonaute Pathways in Flatworms by Santiago Fontenla, Gabriel Rinaldi, Jose F. Tort

“…Our findings showed that complete miRNA and RNAi pathways are present in all analyzed free-living flatworms. Remarkably, whilst all ‘turbellarians’ have Piwi proteins, these were lost in parasitic Neodermantans. …”
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Strategies for Nitrite Replacement in Fermented Sausages and Effect of High Pressure Processing against <i>Salmonella</i> spp. and <i>Listeria innocua</i> by Constanza Maria Lopez, Giuliano Dallolio, Paolo Bonilauri, Annalisa Rebecchi

“…For this purpose, microbiological analysis, pH, water activity (a_w), and a sensory study were performed. All nitrite-free sausages (cold or traditional ripened) showed quality and safety traits similar to low-nitrite traditionally ripened ones used as control. …”
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Differential Antimicrobial Efficacy of Preservative-Free Contact Lens Disinfection Systems against Common Ocular Pathogens by Rhonda Walters, Allison Campolo, Elise Miller, Cindy McAnally, Manal Gabriel, Paul Shannon, Monica Crary

“…All challenges were performed at the manufacturer’s recommended disinfection time. All preservative-free disinfection systems demonstrated similarly high rates of antimicrobial efficacy when challenged with bacteria or fungi, with or without lenses. …”
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Comparing human coding to two natural language processing algorithms in aspirations of people affected by Duchenne Muscular Dystrophy by Carolyn Emily Schwartz

“…Unsupervised NLP was implemented using Latent Dirichlet Allocation (LDA), which extracts latent topics across all the free-text entries. Supervised NLP was done using a Bidirectional Encoder Representations from Transformers (BERT) model, which requires training the algorithm to recognize relevant human-coded themes across free-text entries. …”
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An evaluation of outdoor school environments to promote physical activity in Delhi, India by Samiksha Tarun, Monika Arora, Tina Rawal, Sara E. Benjamin Neelon

“…However, most had playground equipment, courts, and outdoor play areas. Nearly all were free from vandalism and many had murals or art. …”
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Systemic immune reaction in axillary lymph nodes adds to tumor-infiltrating lymphocytes in triple-negative breast cancer prognostication by Fangfang Liu, Thomas Hardiman, Kailiang Wu, Jelmar Quist, Patrycja Gazinska, Tony Ng, Arnie Purushotham, Roberto Salgado, Xiaojing Guo, Sarah E. Pinder, Anita Grigoriadis

“…Our data demonstrate that the number of germinal center formations across all cancer-free LNs, similar to high levels of TILs, is associated with a good prognosis in low TILs TNBC. …”
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Drying Kinetics and Stabilisation of Sludge in Sludge Lagoon by Ong, Bee Yen

“…Decanting supernatant can remove most of the free water, whereas draining or filtration mechanism can remove all the free water and part of the interstitial (capillary) water. …”
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Free-ranging avifauna as a source of generalist parasites for captive birds in zoological settings: An overview of parasite records and potential for cross-transmission by Patricio D. Carrera-Jativa, Eric R. Morgan, Michelle Barrows, Gustavo Jimenez-Uzcategui, Jorky Roosevelt Armijos Tituaña

“…A total of 60 studies from 1987 to 2019 met the eligibility cri¬teria. All examined free-ranging avifauna harbored parasite species that were also reported in zoo birds, except for the European jackdaw. …”
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Drug-free tracheal intubation by specialist paramedics (critical care) in a United Kingdom ambulance service: a service evaluation by Silas Houghton Budd, Eleanor Alexander-Elborough, Richard Brandon, Chris Fudge, Scott Hardy, Laura Hopkins, Ben Paul, Sloane Philips, Sarah Thatcher, Paul Winsor

“…Methods We conducted a retrospective service evaluation of all drug-free tracheal intubation attempts by specialist paramedics (critical care) from South East Coast Ambulance Service NHS Foundation Trust between 1st January and 31st December 2019. …”
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Outcome of shock wave lithotripsy as monotherapy for large solitary renal stones (>2 cm in size) without stenting by Shanmugasundaram Rajaian, Santosh Kumar, Ganesh Gopalakrishnan, Ninan K Chacko, Antony Devasia, Nitin S Kekre

“…The mean follow-up was 18 months (range 3-22 months). Over all, stone-free status was achieved in 50% and success in 81% at 3 months. …”
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Influência do comportamento gregário nos processos de muda de Rhipicephalus sanguineus (Latreille, 1806) (acari: ixodidae), em condições laboratoriais Influence of aggregation on t... by Paulo Henrique D. Cançado, Eliane M. Piranda, João Luiz H. Faccini

“…A total of 10 rabbits were used on the experiment. All tick free-living phases were kept in incubator at 27±1ºC, 80±5% relative humidity and scotophase. …”
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Training the Trainers in Microsurgery: A Success Story from Vietnam’s Hanoi National Hospital of Odonto-stomatology by Hong Nhung Nguyen, MD, Jill Chen, MBChB, Tan Van Nguyen, MD, Duc Thanh Le, MD, Tai Son Nguyen, MD, Seng-Feng Jeng, MD

“…In the pioneering stage (2008-2011), without surgical microscopes, all five free flaps failed. After acquiring a microscope and mentoring from Hanoi's 108 Military Hospital, mandibular bone defect reconstruction with free fibula flaps had 85% success rate. …”
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The value of intra-operative ultrasonography on safety margin and outcome during liver resection and radio-frequency ablation in the management of hepatocellular carcinoma patients by Mohamed Mogahed, Ashraf Anas Zytoon, Ahmed Abdel Haleem, ElSayed Imam, Nashwa Ghanem, Wessam M. Abdellatif

“…Results In the open resection group, the 32 cases of 52 for whom IOUS was performed, all had free surgical margin (100%) while 18 of 20 patients studied retrospectively without IOUS had free surgical margin (90%). …”
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A randomized, controlled study to assess the efficacy and safety of lotilaner (Credelio™) in controlling ticks in client-owned dogs in Europe by Daniela Cavalleri, Martin Murphy, Wolfgang Seewald, Jason Drake, Steve Nanchen

“…For FSM (n = 68), efficacy remained at least 96% through Day 84, but at no point were all dogs free of live attached ticks. Mean counts in lotilaner-treated dogs were significantly lower than FSM-treated dogs on Days 7, 42, 70 and 84 (P < 0.05). …”
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Chitosan-Enriched Solution Blow Spun Poly(Ethylene Oxide) Nanofibers with Poly(Dimethylsiloxane) Hydrophobic Outer Layer for Skin Healing and Regeneration by Emilia Szymańska, Michał Wojasiński, Robert Czarnomysy, Renata Dębowska, Iwona Łopianiak, Kamil Adasiewicz, Tomasz Ciach, Katarzyna Winnicka

“…Unmodified nanofibers displayed highly porous structure with the presence of uniform, randomly aligned nanofibers, in contrast to coated materials in which almost all the free spaces were filled in with poly(dimethylsiloxane). …”
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