Processing of Polyvinyl Acetate Phthalate in Hot-Melt Extrusion—Preparation of Amorphous Solid Dispersions by Marius Monschke, Kevin Kayser, Karl G. Wagner

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Oral Delivery of Niclosamide as an Amorphous Solid Dispersion That Generates Amorphous Nanoparticles during Dissolution by Miguel O. Jara, Zachary N. Warnken, Sawittree Sahakijpijarn, Rishi Thakkar, Vineet R. Kulkarni, Dale J. Christensen, John J. Koleng, Robert O. Williams

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A continuum theory of amorphous solids undergoing large deformations, with application to polymeric glasses by Anand, Lallit

Subjects: “…amorphous solids…”
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Strategies to improve the stability of amorphous solid dispersions in view of the hot melt extrusion (HME) method by AL-japairai, Khater Ahmed Saeed, Almurisi, Samah Hamed, Syed, Mahmood, Madheswaran, Thiagarajan, Chatterjee, Bappaditya, Sri, Prasanthi, Nadiatul Azra, Ahmad Mazlan, Al Hagbani, Turki, Alheibshy, Fawaz

“…However, drug formulation for oral administration is often hindered by the drug's poor solubility, which limits its bioavailability and reduces its commercial value. As a solution, amorphous solid dispersion (ASD) was introduced as a drug formulation method that improves drug solubility by changing the molecular structure of the drugs from crystalline to amorphous. …”
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The Development and Optimization of Hot-Melt Extruded Amorphous Solid Dispersions Containing Rivaroxaban in Combination with Polymers by Jong-Hwa Lee, Hyeong Sik Jeong, Jong-Woo Jeong, Tae-Sung Koo, Do-Kyun Kim, Young Ho Cho, Gye Won Lee

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A Novel Desloratadine-Benzoic Acid Co-Amorphous Solid: Preparation, Characterization, and Stability Evaluation by Ahmad Ainurofiq, Rachmat Mauludin, Diky Mudhakir, Sundani Nurono Soewandhi

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Formulation of Orally Disintegrating Films as an Amorphous Solid Solution of a Poorly Water-Soluble Drug by Pattaraporn Panraksa, Pratchaya Tipduangta, Kittisak Jantanasakulwong, Pensak Jantrawut

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Thermodynamic Modeling of the Amorphous Solid Dispersion-Water Interfacial Layer and Its Impact on the Release Mechanism by Stefanie Dohrn, Samuel O. Kyeremateng, Esther Bochmann, Ekaterina Sobich, Andrea Wahl, Bernd Liepold, Gabriele Sadowski, Matthias Degenhardt

Subjects: “…amorphous solid dispersion (ASD)…”
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Solubility and Physical Stability Enhancement of Loratadine by Preparation of Co-Amorphous Solid Dispersion with Chlorpheniramine and Polyvinylpyrrolidone by Krit Suknuntha, Nattakanwadee Khumpirapang, Vimon Tantishaiyakul, Siriporn Okonogi

“…The results from XRPD and DSC confirmed the amorphous form of LRD in the co-amorphous solid dispersions. The FTIR results indicated that there was no intermolecular interaction between LRD, CPM, and PVP. …”
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The Value of Bead Coating in the Manufacturing of Amorphous Solid Dispersions: A Comparative Evaluation with Spray Drying by Eline Boel, Felien Reniers, Wim Dehaen, Guy Van den Mooter

Subjects: “…amorphous solid dispersion…”
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Spray-Dried Paracetamol/Polyvinylpyrrolidone Amorphous Solid Dispersions: Part I—Stability of Powders and Tablets by Lena Ritters, Yuanyuan Tian, Stephan Reichl

Subjects: “…amorphous solid dispersion…”
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Hierarchical Particle Approach for Co-Precipitated Amorphous Solid Dispersions for Use in Preclinical In Vivo Studies by Luke Schenck, Christopher Boyce, Derek Frank, Sampada Koranne, Heidi M. Ferguson, Neil Strotman

Subjects: “…amorphous solid dispersion…”
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Hot Melt Extruded Posaconazole-Based Amorphous Solid Dispersions—The Effect of Different Types of Polymers by Daniel Kramarczyk, Justyna Knapik-Kowalczuk, Mateusz Kurek, Witold Jamróz, Renata Jachowicz, Marian Paluch

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Dissolution-permeation of hot-melt extruded amorphous solid dispersion comprising an experimental grade of HPMCAS by Hironori Tanaka, Tetsuya Miyano, Hiroshi Ueda

“… Background and purpose: Physicochemical properties of an amorphous solid dispersion (ASD) comprising an experimental grade of hydroxypropyl methylcellulose acetate succinate (HPMCAS-MX) with lower glass transition temperature have been previously investigated. …”
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Development of the Amorphous Solid Dispersion of Curcumin: A Rational Selection of Polymers for Enhanced Solubility and Dissolution by Memoona Ishtiaq, Sajid Asghar, Ikram Ullah Khan, Muhammad Shahid Iqbal, Syed Haroon Khalid

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Surface Reaction of Methyl Mercaptan (CH3SH) with Hydrogen Atoms on Amorphous Solid Water by Thanh Nguyen, Yasuhiro Oba, W. M. C. Sameera, Kenji Furuya, Akira Kouchi, Naoki Watanabe

“…In this study, we investigated the surface reactions of solid CH _3 SH with H atoms on amorphous solid water using experimental and computational methods to examine their physicochemical behavior in the ISM. …”
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Kinetics of Water-Induced Amorphous Phase Separation in Amorphous Solid Dispersions via Raman Mapping by Adrian Krummnow, Andreas Danzer, Kristin Voges, Samuel O. Kyeremateng, Matthias Degenhardt, Gabriele Sadowski

“…This formulation strategy is commonly known as amorphous solid dispersion (ASD). API crystallization and/or amorphous phase separation can be detrimental to the bioavailability. …”
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Polyelectrolyte Matrices in the Modulation of Intermolecular Electrostatic Interactions for Amorphous Solid Dispersions: A Comprehensive Review by Anastasia Tsiaxerli, Anna Karagianni, Andreas Ouranidis, Kyriakos Kachrimanis

Subjects: “…amorphous solid dispersions…”
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Bioavailability Improvement of Carbamazepine via Oral Administration of Modified-Release Amorphous Solid Dispersions in Rats by Houli Li, Meimei Zhang, Lilong Xiong, Weiyi Feng, Robert O. Williams

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Effect of Span 20 Feeding Zone in the Twin Screw Extruder on the Properties of Amorphous Solid Dispersion of Ritonavir by Hengqian Wu, Zhengping Wang, Yanna Zhao, Yan Gao, Heng Zhang, Lili Wang, Zhe Wang, Jun Han

Subjects: “…amorphous solid dispersion…”
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