Improved Dissolution and Pharmacokinetics of Abiraterone through KinetiSol^® Enabled Amorphous Solid Dispersions by Urvi Gala, Dave Miller, Robert O. Williams

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Microwave-Induced In Situ Amorphization: A New Strategy for Tackling the Stability Issue of Amorphous Solid Dispersions by Wei Qiang, Korbinian Löbmann, Colin P. McCoy, Gavin P. Andrews, Min Zhao

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The Investigation of Flory–Huggins Interaction Parameters for Amorphous Solid Dispersion Across the Entire Temperature and Composition Range by Yiwei Tian, Kaijie Qian, Esther Jacobs, Esther Amstad, David S. Jones, Lorenzo Stella, Gavin P. Andrews

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Unravelling the Miscibility of Poly(2-oxazoline)s: A Novel Polymer Class for the Formulation of Amorphous Solid Dispersions by Melissa Everaerts, Ali Tigrine, Victor R. de la Rosa, Richard Hoogenboom, Peter Adriaensens, Christian Clasen, Guy Van den Mooter

Subjects: “…amorphous solid dispersions…”
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Development of a Surface Coating Technique with Predictive Value for Bead Coating in the Manufacturing of Amorphous Solid Dispersions by Eline Boel, Piyush Panini, Guy Van den Mooter

“…The aim of this paper was to investigate whether a surface coating technique could be developed that can predict the phase behavior of amorphous solid dispersions (ASDs) coated on beads. ASDs of miconazole (MIC) and poly(vinylpyrrolidone-<i>co</i>-vinyl acetate) (PVP-VA) in methanol (MeOH) were studied as a model system. …”
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Selecting the most appropriate formulation excipient for manufacture of amorphous solid dispersions: a case study of lumefantrine by Dijia Liu, Shu Li, David Jones, Gavin Paul Andrews

Subjects: “…amorphous solid dispersion…”
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Development and Characterization of an Amorphous Solid Dispersion of Furosemide in the Form of a Sublingual Bioadhesive Film to Enhance Bioavailability by Viviana De Caro, Alessia Ajovalasit, Flavia Maria Sutera, Denise Murgia, Maria Antonietta Sabatino, Clelia Dispenza

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Drug-Rich Phases Induced by Amorphous Solid Dispersion: Arbitrary or Intentional Goal in Oral Drug Delivery? by Kaijie Qian, Lorenzo Stella, David S. Jones, Gavin P. Andrews, Huachuan Du, Yiwei Tian

Subjects: “…amorphous solid dispersion…”
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A Hot-Melt Extrusion Risk Assessment Classification System for Amorphous Solid Dispersion Formulation Development by Samuel O. Kyeremateng, Kristin Voges, Stefanie Dohrn, Ekaterina Sobich, Ute Lander, Stefan Weber, David Gessner, Rachel C. Evans, Matthias Degenhardt

Subjects: “…amorphous solid dispersion…”
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A family of oxychloride amorphous solid electrolytes for long-cycling all-solid-state lithium batteries by Shumin Zhang, Feipeng Zhao, Jiatang Chen, Jiamin Fu, Jing Luo, Sandamini H. Alahakoon, Lo-Yueh Chang, Renfei Feng, Mohsen Shakouri, Jianwen Liang, Yang Zhao, Xiaona Li, Le He, Yining Huang, Tsun-Kong Sham, Xueliang Sun

“…Herein, we report a new family of amorphous solid electrolytes, xLi2O-MCly (M = Ta or Hf, 0.8 ≤ x ≤ 2, y = 5 or 4). xLi2O-MCly amorphous solid electrolytes can achieve desirable ionic conductivities up to 6.6 × 10−3 S cm−1 at 25 °C, which is one of the highest values among all the reported amorphous solid electrolytes and comparable to those of the popular crystalline ones. …”
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Exploring the Role of Surfactants in Enhancing Drug Release from Amorphous Solid Dispersions at Higher Drug Loadings by Sugandha Saboo, Pradnya Bapat, Dana E. Moseson, Umesh S. Kestur, Lynne S. Taylor

Subjects: “…amorphous solid dispersions…”
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Evaluation of Pharmacobezoar Formation from Suspensions of Spray-Dried Amorphous Solid Dispersions: An MRI Study in Rats by Hannes Gierke, Susan Mouchantat, Sabine Berg, Michael Grimm, Stefan Hadlich, Marie-Luise Kromrey, Thomas Nolte, Teresa Pfrommer, Vincent Rönnpagel, Adrian Rump, Kerstin Schaefer, Ann-Cathrin Willmann, Werner Weitschies

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Amorphous Solid Dispersions and the Contribution of Nanoparticles to In Vitro Dissolution and In Vivo Testing: Niclosamide as a Case Study by Miguel O. Jara, Zachary N. Warnken, Robert O. Williams

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Structural characterisation of amorphous solid dispersions via metropolis matrix factorisation of pair distribution function data by Geddes, H, Blade, H, McCabe, J, Hughes, L, Goodwin, A

“…We measure the X-ray pair distribution functions (PDFs) of a series of felodipine:copovidone amorphous solid dispersions. Using a newly-developed Metropolis Matrix Factorisation (MMF) algorithm we extract from these data the PDF of the amorphous felodipine component in isolation. …”

Mechanochemical Approach to Obtaining a Multicomponent Fisetin Delivery System Improving Its Solubility and Biological Activity by Natalia Rosiak, Ewa Tykarska, Judyta Cielecka-Piontek

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Selection of appropriate dapsone and poly(1-vinylpyrrolidone-co-vinyl acetate) ratios for the preparation of amorphous solid dispersions by Dinesh Choudhury, Upadhyayula Suryanarayana Murty, Subham Banerjee

“…Drug-polymer miscibility is a critical requirement for the efficient design and development of amorphous solid dispersions. The objective of the current study was to determine the miscibility between dapsone (DAP) and poly(1-vinylpyrrolidone-co-vinyl acetate) (PVP-VA) through theoretical and experimental approaches, including the use of a thermodynamic phase diagram and Gibbs free energy of mixing. …”
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3D printing of amorphous solid dispersions: A comparison of fused deposition modeling and drop-on-powder printing by Nadine Gottschalk, Malte Bogdahn, Julian Quodbach

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Amorphous Solid Dispersions (ASDs): The Influence of Material Properties, Manufacturing Processes and Analytical Technologies in Drug Product Development by Raman Iyer, Vesna Petrovska Jovanovska, Katja Berginc, Miha Jaklič, Flavio Fabiani, Cornelius Harlacher, Tilen Huzjak, Manuel Vicente Sanchez-Felix

Subjects: “…amorphous solid dispersions…”
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Itraconazole Amorphous Solid Dispersion Tablets: Formulation and Compaction Process Optimization Using Quality by Design Principles and Tools by Hetvi Triboandas, Kendal Pitt, Mariana Bezerra, Delphine Ach-Hubert, Walkiria Schlindwein

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The applications of machine learning to predict the forming of chemically stable amorphous solid dispersions prepared by hot-melt extrusion by Junhuang Jiang, Anqi Lu, Xiangyu Ma, Defang Ouyang, Robert O. Williams, III

Subjects: “…Amorphous Solid Dispersion…”
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