Enhancing the dissolution rate of poorly soluble drug Febuxostat using spray dried amorphous solid dispersion technique by Vaishali Patel, Anita Patel, Ashish Shah

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Co-Amorphous Solid Dispersions for Solubility and Absorption Improvement of Drugs: Composition, Preparation, Characterization and Formulations for Oral Delivery by Anna Karagianni, Kyriakos Kachrimanis, Ioannis Nikolakakis

Subjects: “…co-amorphous solid dispersions…”
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Effect of Drug–Polymer Interaction in Amorphous Solid Dispersion on the Physical Stability and Dissolution of Drugs: The Case of Alpha-Mangostin by Arif Budiman, Neng Vera Nurani, Eli Laelasari, Muchtaridi Muchtaridi, Sriwidodo Sriwidodo, Diah Lia Aulifa

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Preparation of Azithromycin Amorphous Solid Dispersion by Hot-Melt Extrusion: An Advantageous Technology with Taste Masking and Solubilization Effects by Jiale Li, Conghui Li, Hui Zhang, Xiang Gao, Ting Wang, Zengming Wang, Aiping Zheng

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Relevance of Liquid-Liquid Phase Separation of Supersaturated Solution in Oral Absorption of Albendazole from Amorphous Solid Dispersions by Kyosuke Suzuki, Kohsaku Kawakami, Masafumi Fukiage, Michinori Oikawa, Yohei Nishida, Maki Matsuda, Takuya Fujita

Subjects: “…amorphous solid dispersions…”
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Drug Amorphous Solid Dispersions Based on Poly(vinyl Alcohol): Evaluating the Effect of Poly(propylene Succinate) as Plasticizer by Afroditi Kapourani, Artemis Palamidi, Konstantinos N. Kontogiannopoulos, Nikolaos D. Bikiaris, Panagiotis Barmpalexis

Subjects: “…amorphous solid dispersions…”
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Amorphous solid dispersion preparation via coprecipitation improves the dissolution, oral bioavailability, and intestinal health enhancement properties of magnolol by Jia Cao, Shixia Zhang, Yanshuang Hao, Kai Fan, Lingling Wang, Xinghua Zhao, Xin He

“…The powder samples prepared via antisolvent coprecipitation did not exhibit a crystal diffraction peak of MAG in powder X-ray diffractions or melting point peak in differential scanning calorimetry, proving the successful preparation of an amorphous solid dispersion system. The in vitro dissolution assay showed that the cumulative dissolution rate of MAG-HPMCAS(LF) SD (2:8, w/w) was 100%. …”
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Developing pH-Modulated Spray Dried Amorphous Solid Dispersion of Candesartan Cilexetil with Enhanced In Vitro and In Vivo Performance by Surendra Poudel, Dong Wuk Kim

Subjects: “…amorphous solid dispersion…”
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Influence of Drug Load on the Printability and Solid-State Properties of 3D-Printed Naproxen-Based Amorphous Solid Dispersion by Eric Ofosu Kissi, Robin Nilsson, Liebert Parreiras Nogueira, Anette Larsson, Ingunn Tho

“…This shows that adjusting the drug ratio can modulate the brittleness and improve printability without compromising the physical stability of the amorphous solid dispersion.…”
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The Amorphous Solid Dispersion of Chrysin in Plasdone^® S630 Demonstrates Improved Oral Bioavailability and Antihyperlipidemic Performance in Rats by Chenhui Wang, Xiaowei Liu, Ruihan Zhao, Meiqing Yang, Wenqian Liu, Qiuyang Dai, Xiaofeng Bao, Yong Chen, Jun Ma

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Impact of Laser Speed and Drug Particle Size on Selective Laser Sintering 3D Printing of Amorphous Solid Dispersions by Rishi Thakkar, Miguel O. Jara, Steve Swinnea, Amit R. Pillai, Mohammed Maniruzzaman

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Inhibition of Liquid–Liquid Phase Separation for Breaking the Solubility Barrier of Amorphous Solid Dispersions to Improve Oral Absorption of Naftopidil by Masafumi Fukiage, Kyosuke Suzuki, Maki Matsuda, Yohei Nishida, Michinori Oikawa, Takuya Fujita, Kohsaku Kawakami

“…Amorphous solid dispersion (ASD) is one of the most promising technologies for improving the oral absorption of poorly soluble compounds. …”
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Crystallization Tendency of Pharmaceutical Glasses: Relevance to Compound Properties, Impact of Formulation Process, and Implications for Design of Amorphous Solid Dispersions by Kohsaku Kawakami

“…Amorphous solid dispersions (ASDs) are important formulation strategies for improving the dissolution process and oral bioavailability of poorly soluble drugs. …”
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Methanol Formation through Reaction of Low-energy CH3 + Ions with an Amorphous Solid Water Surface at Low Temperature by Y. Nakai, W. M. C. Sameera, K. Furuya, H. Hidaka, A. Ishibashi, N. Watanabe

“…We have performed experimental investigations of methanol formation via the reactions of low-energy CH _3 ^+ ions with an amorphous solid water (ASW) surface at ∼10 K. A newly developed experimental apparatus enabled irradiation of the ASW surface by several eV ions and detection of trace amounts of reaction products on the surface. …”
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Amorphization of Thiamine Mononitrate: A Study of Crystallization Inhibition and Chemical Stability of Thiamine in Thiamine Mononitrate Amorphous Solid Dispersions by Seda Arioglu-Tuncil, Adrienne L. Voelker, Lynne S. Taylor, Lisa J. Mauer

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Ionic conduction study of enhanced amorphous solid bio-polymer electrolytes based carboxymethyl cellulose doped NH4Br by Ahmad Salihin, Samsudin, M. A., Saadiah

“…The present work deal with the development of enhanced amorphous solid bio-polymer electrolytes (SPEs) based on carboxymethyl cellulose (CMC) doped ammonium bromide (NH4Br) and plasticized with various composition of ethylene carbonate (EC). …”
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Spray-Dried Amorphous Solid Dispersions of Griseofulvin in HPC/Soluplus/SDS: Elucidating the Multifaceted Impact of SDS as a Minor Component by Mahbubur Rahman, Stephanie Ahmad, James Tarabokija, Nathaniel Parker, Ecevit Bilgili

Subjects: “…amorphous solid dispersions…”
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Investigation of Dissolution Mechanism and Release Kinetics of Poorly Water-Soluble Tadalafil from Amorphous Solid Dispersions Prepared by Various Methods by Tereza Školáková, Michaela Slámová, Andrea Školáková, Alena Kadeřábková, Jan Patera, Petr Zámostný

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A Novel Aminomethacrylate-Based Copolymer for Solubility Enhancement—From Radical Polymer Synthesis to Manufacture and Characterization of Amorphous Solid Dispersions by Fabian-Pascal Schmied, Alexander Bernhardt, Christian Moers, Christian Meier, Thomas Endres, Sandra Klein

“…Of all the (co-)polymers included in the study, ModE with a molecular weight of 173 kDa showed the best performance in terms of desired properties and was shown to be particularly suitable for preparing amorphous solid dispersions (ASDs) of the three model drugs, which in a first set of dissolution experiments showed better release behavior under pH conditions of the fasting stomach than higher molecular weight ModE types, as well as a variety of commercially available (co-)polymers. …”
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Molecular Simulation and Statistical Learning Methods toward Predicting Drug–Polymer Amorphous Solid Dispersion Miscibility, Stability, and Formulation Design by Daniel M. Walden, Yogesh Bundey, Aditya Jagarapu, Victor Antontsev, Kaushik Chakravarty, Jyotika Varshney

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