Showing 281 - 300 results of 2,522 for search '"Amyloid beta"', query time: 0.37s Refine Results
  1. 281

    Relationship of amyloid beta and neurofibrillary tau deposition in Neurodegeneration in Aging Down Syndrome (NiAD) study at baseline by DL Tudorascu, CM Laymon, M Zammit, DS Minhas, SJ Anderson, PA Ellison, S Zaman, BM Ances, M Sabbagh, SC Johnson, CA Mathis, WE Klunk, BL Handen, BT Christian, AD Cohen

    Published 2020-01-01
    “…Our previous studies have assessed longitudinal changes in amyloid beta (Aβ) accumulation in DS. Objective The goal of the present study was to assess the presence of brain tau using [18F]AV‐1451 positron emission tomography (PET) in DS and to assess the relationship of brain tau pathology to Aβ using Pittsburgh Compound B (PiB)‐PET. …”
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    Article
  2. 282

    Synthetic amyloid beta does not induce a robust transcriptional response in innate immune cell culture systems by I. Y. Quiroga, A. E. Cruikshank, M. L. Bond, K. S. M. Reed, B. A. Evangelista, J. H. Tseng, J. V. Ragusa, R. B. Meeker, H. Won, S. Cohen, T. J. Cohen, D. H. Phanstiel

    Published 2022-04-01
    “…The accumulation of amyloid beta (Aβ) in the brain has historically been associated with AD, and recent evidence suggests that neuroinflammation plays a central role in its origin and progression. …”
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    Article
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    Near-infrared fluorescence molecular imaging of amyloid beta species and monitoring therapy in animal models of Alzheimer’s disease by Zhang, Xueli, Tian, Yanli, Zhang, Can, Tian, Xiaoyu, Ross, Alana W., Moir, Robert D., Sun, Hongbin, Tanzi, Rudolph E., Moore, Anna V., Ran, Chongzhao

    Published 2016
    “…Although several NIRF probes for detecting amyloid beta (Aβ) species of AD have been reported, none of these probes has been used to monitor changes of Aβs during therapy. …”
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    Article
  12. 292

    Non-Conjugated Small Molecule FRET for Differentiating Monomers from Higher Molecular Weight Amyloid Beta Species by Ran, Chongzhao, Zhao, Wei, Moir, Robert D., Moore, Anna V.

    Published 2011
    “…Principal Findings: We demonstrated the feasibility of a non-conjugated FRET (Förster resonance energy transfer) technique that utilized amyloid beta (Aβ) species as intrinsic platforms for the FRET pair assembly. …”
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    Article
  13. 293

    Human-like rodent amyloid-beta-peptide determines Alzheimer pathology in aged wild-type Octodon degu. by Inestrosa, N, Reyes, A, Chacón, M, Cerpa, W, Villalón, A, Montiel, J, Merabachvili, G, Aldunate, R, Bozinovic, F, Aboitiz, F

    Published 2005
    “…We report here that an aged wild-type South American rodent, Octodon degu, expresses neuronal beta-amyloid precursor protein (beta-APP695) displaying both intracellular and extracellular deposits of amyloid-beta-peptide (Abeta), intracellular accumulations of tau-protein and ubiquitin, a strong astrocytic response and acetylcholinesterase (AChE)-rich pyramidal neurons. …”
    Journal article
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    Hippocampal injections of soluble amyloid-beta oligomers alter electroencephalographic activity during wake and slow-wave sleep in rats by Audrey Hector, Chloé Provost, Benoît Delignat-Lavaud, Khadija Bouamira, Chahinez-Anissa Menaouar, Valérie Mongrain, Jonathan Brouillette

    Published 2023-10-01
    “…Abstract Background Soluble amyloid-beta oligomers (Aβo) begin to accumulate in the human brain one to two decades before a clinical diagnosis of Alzheimer’s disease (AD). …”
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  19. 299

    Cellulose ether treatment inhibits amyloid beta aggregation, neuroinflammation and cognitive deficits in transgenic mouse model of Alzheimer’s disease by Tahir Ali, Antonia N. Klein, Keegan McDonald, Lovisa Johansson, Priyanka Ganguli Mukherjee, Martin Hallbeck, Katsumi Doh-ura, Hermann M. Schatzl, Sabine Gilch

    Published 2023-07-01
    “…Pathogenesis of AD is associated with the aggregation and accumulation of amyloid beta (Aβ), a major neurotoxic mediator that triggers neuroinflammation and memory impairment. …”
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    Article
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