Review Paper: Tau Pathology of Alzheimer Disease: Possible Role of Sleep Deprivation by Nahid Ahmadian, Sajjad Hejazi, Javad Mahmoudi, Mahnaz Talebi

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APP Causes Hyperexcitability in Fragile X Mice by Cara Jean Westmark, Shih-Chieh Chuang, Seth A Hays, Mikolaj J Filon, Brian C Ray, Pamela R Westmark, Jay R Gibson, Kimberly M Huber, Robert KS Wong

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The Study of Interactions between Amyloid-Beta Precursor Protein and Functional Nanomotors as a New anti-Alzheimer\'s Disease Strategy by Modeling and Computer Simulation by Saeideh Jafarinezhad, Mahmood Dehghani Ashkezari, Ali Jebali

“…Introduction: The aim of this study was to evaluate the performance of three nanomotors on 15 transmembrane amyloid-beta precursor proteins by molecular dynamics simulation. …”
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Amyloid beta deposition related retinal pigment epithelium cell impairment and subretinal microglia activation in aged APPswePS1 transgenic mice by Zhi-Zhang Dong, Juan Li, Yi-Feng Gan, Xue-Rong Sun, Yun-Xia Leng, Jian Ge

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Dietary supplementation with Salvia officinalis L. and aerobic training attenuates memory deficits via the CREB-BDNF pathway in amyloid beta- injected rats by Iman Mohseni, Maghsoud Peeri, Mohamad Ali Azarbayjani

“…Objective: The aim of this study was to determine the effects of aerobic training and Salvia officinalis extract on the improvement of learning and memory deficits in amyloid beta -injected rats. Methods: Rats were injected with an Aβ solution into the CA1 hippocampal region. …”
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Oligomeric amyloid-beta induces MAPK-mediated activation of brain cytosolic and calcium-independent phospholipase A2 in a spatial-specific manner by Juan Pablo Palavicini, Chunyan Wang, Linyuan Chen, Kristen Hosang, Jianing Wang, Takami Tomiyama, Hiroshi Mori, Xianlin Han

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Amyloid Beta Pathology Exacerbates Weight Loss and Brain Cytokine Responses following Low-Dose Lipopolysaccharide in Aged Female Tg2576 Mice by Rachel C. Knopp, Kristen K. Baumann, Miranda L. Wilson, William A. Banks, Michelle A. Erickson

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Correlation of Plasmatic Amyloid Beta Peptides (Aβ-40, Aβ-42) with Myocardial Injury and Inflammatory Biomarkers in Acute Coronary Syndrome by Luis Eduardo Del Moral, Claudia Lerma, Héctor González-Pacheco, Alan Cristhian Chávez-Lázaro, Felipe Massó, Emma Rodriguez

“…<b>Background/Objective:</b> Amyloid beta (β) -40 levels increase with age and inflammation states and appear to be associated with clinical manifestations of acute coronary syndrome (ACS). …”
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Synergistic effects of amyloid-beta and wild-type human tau on dendritic spine loss in a floxed double transgenic model of Alzheimer's disease by Meredith A. Chabrier, David Cheng, Nicholas A. Castello, Kim N. Green, Frank M. LaFerla

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A dual brain-targeting curcumin-loaded polymersomes ameliorated cognitive dysfunction in intrahippocampal amyloid-&beta;1&ndash;42-injected mice by Jia TT, Sun ZG, Lu Y, Gao J, Zou H, Xie FY, Zhang GQ, Xu H, Sun DX, Yu Y, Zhong YQ

“…The curcumin-encapsulated Tf/Tet-1-POs provided neuroprotection and ameliorated cognitive dysfunction in intrahippocampal amyloid-&beta;1&ndash;42-injected mice. These results suggest that the dual brain-targeting POs are more capable of drug delivery to the brain that can be exploited as a multiple noninvasive vehicle for targeting therapeutics. …”
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Exploration of the Molecular Mechanism for Lipoprotein Lipase Expression Variations in SH-SY5Y Cells Exposed to Different Doses of Amyloid-Beta Protein by Jingzhu Zhang, Yufan Liu, Sihui Wang, Ran Que, Weidong Zhao, Weidong Zhao, Li An

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High Correlation among Brain-Derived Major Protein Levels in Cerebrospinal Fluid: Implication for Amyloid-Beta and Tau Protein Changes in Alzheimer’s Disease by Kyoka Hoshi, Mayumi Kanno, Mitsunari Abe, Takenobu Murakami, Yoshikazu Ugawa, Aya Goto, Takashi Honda, Takashi Saito, Takaomi C. Saido, Yoshiki Yamaguchi, Masakazu Miyajima, Katsutoshi Furukawa, Hiroyuki Arai, Yasuhiro Hashimoto

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Beta-Secretase 1 Recruits Amyloid-Beta Precursor Protein to ROCK2 Kinase, Resulting in Erroneous Phosphorylation and Beta-Amyloid Plaque Formation by István Hajdú, Barbara M. Végh, András Szilágyi, Péter Závodszky

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An α5 GABAA Receptor Inverse Agonist, α5IA, Attenuates Amyloid Beta-Induced Neuronal Death in Mouse Hippocampal Cultures by Chitra Vinnakota, Karan Govindpani, Warren Perry Tate, Katie Peppercorn, Praju Vikas Anekal, Henry John Waldvogel, Richard Lewis Maxwell Faull, Andrea Kwakowsky

“…This study aimed to characterize the effects of α5IA on amyloid beta (Aβ_1–42)-induced molecular and cellular changes. …”
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Amyloid beta peptides (Aβ) from Alzheimer's disease neuronal secretome induce endothelial activation in a human cerebral microvessel model by Yu Jung Shin, Kira M. Evitts, Solhee Jin, Caitlin Howard, Margaret Sharp-Milgrom, Tiara Schwarze-Taufiq, Chizuru Kinoshita, Jessica E. Young, Ying Zheng

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Amyloid Beta Oligomers-Induced Ca²⁺ Entry Pathways: Role of Neuronal Networks, NMDA Receptors and Amyloid Channel Formation by Erica Caballero, Elena Hernando-Pérez, Victor Tapias, María Calvo-Rodríguez, Carlos Villalobos, Lucía Núñez

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Amyloid-beta–copper interaction studied by simultaneous nitrogen K and copper L2,3-edge soft X-ray absorption spectroscopy by Jinghui Luo, Hongzhi Wang, Jinming Wu, Vladyslav Romankov, Niéli Daffé, Jan Dreiser

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Facilitation of Gastrointestinal (GI) Tract Microbiome-Derived Lipopolysaccharide (LPS) Entry Into Human Neurons by Amyloid Beta-42 (Aβ42) Peptide by Walter J. Lukiw, Walter J. Lukiw, Walter J. Lukiw, Wenhong Li, Wenhong Li, Taylor Bond, Yuhai Zhao, Yuhai Zhao

“…In this “Perspectives article” we discuss current advances, and consider future directions in this research area, and provide novel evidence in human neuronal-glial (HNG) cells in primary culture that the co-incubation of LPS with amyloid-beta 42 (Aβ42) peptide facilitates the association of LPS with neuronal cells. …”
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Phyllanthus emblica L. (Indian gooseberry) extracts protect against retinal degeneration in a mouse model of amyloid beta-induced Alzheimer’s disease by Holim Jang, Phisamai Srichayet, Woo Jung Park, Ho Jin Heo, Dae-Ok Kim, Sasitorn Tongchitpakdee, Tae-Jin Kim, Sang Hoon Jung, Chang Yong Lee

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Exploring How Low Oxygen Post Conditioning Improves Stroke-Induced Cognitive Impairment: A Consideration of Amyloid-Beta Loading and Other Mechanisms by Zidan Zhao, Zidan Zhao, Zidan Zhao, Rebecca J. Hood, Rebecca J. Hood, Rebecca J. Hood, Lin Kooi Ong, Lin Kooi Ong, Lin Kooi Ong, Lin Kooi Ong, Lin Kooi Ong, Giovanni Pietrogrande, Giovanni Pietrogrande, Giovanni Pietrogrande, Sonia Sanchez Bezanilla, Sonia Sanchez Bezanilla, Sonia Sanchez Bezanilla, Kirby E. Warren, Kirby E. Warren, Kirby E. Warren, Marina Ilicic, Marina Ilicic, Marina Ilicic, Murielle G. Kluge, Murielle G. Kluge, Murielle G. Kluge, Clifford TeBay, Clifford TeBay, Clifford TeBay, Ole P. Ottersen, Ole P. Ottersen, Sarah J. Johnson, Sarah J. Johnson, Michael Nilsson, Michael Nilsson, Michael Nilsson, Michael Nilsson, Frederick R. Walker, Frederick R. Walker, Frederick R. Walker, Frederick R. Walker, Frederick R. Walker

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