Molecular docking studies on the interaction of anti-alzheimer compounds with amyloid beta peptides by Faujan, Nur Hana, Zakaria, Norzalina, Mohammad, Nurul Najihah

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JBPOS0101 regulates amyloid beta, tau, and glial cells in an Alzheimer's disease model. by Jihoon Jeong, Hyung Joon Park, Bo-Ram Mun, Ju Kyong Jang, Yong Moon Choi, Won-Seok Choi

“…The deposition of amyloid beta (Aβ) and tau hyperphosphorylation are hallmarks of AD and are major therapeutic targets. …”
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HHV-6A infection induces amyloid-beta expression and activation of microglial cells by Daria Bortolotti, Valentina Gentili, Antonella Rotola, Elisabetta Caselli, Roberta Rizzo

“…Abstract Background The control of viral infections in the brain involves the activation of microglial cells, the macrophages of the brain that are constantly surveying the central nervous system, and the production of amyloid-beta (Aβ) as an anti-microbial molecule. Recent findings suggest a possible implication of HHV-6A in AD. …”
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Evaluating the inter-species transmission risk of amyloid beta peptide aggregates via ingestion by Joshua Raine, Nicholas Tolwinski, Jan Gruber, Ajay S. Mathuru

“…Abstract Background Recent reports suggest that amyloid beta (Aβ) peptides can exhibit prion-like pathogenic properties. …”
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Turn-on chemiluminescence probes and dual-amplification of signal for detection of amyloid beta species in vivo by Jing Yang, Wei Yin, Richard Van, Keyi Yin, Peng Wang, Chao Zheng, Biyue Zhu, Kathleen Ran, Can Zhang, Mohanraja Kumar, Yihan Shao, Chongzhao Ran

“…Detection of amyloid beta deposits is often performed with fluorescent compounds that bind plaques. …”
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C5a Increases the Injury to Primary Neurons Elicited by Fibrillar Amyloid Beta by Michael X. Hernandez, Pouya Namiranian, Eric Nguyen, Maria I. Fonseca, Andrea J. Tenner

“…Primary mouse neurons treated with both 100 nM C5a and 5 µM fibrillar amyloid beta (fAβ), to model what occurs in the AD brain, showed increased MAP-2 loss relative to either C5a or fAβ alone. …”
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Immunotherapy for the treatment of Alzheimer's disease: amyloid-β or tau, which is the right target? by Castillo-Carranza DL, Guerrero-Muñoz MJ, Kayed R

“…Diana L Castillo-Carranza,1,2 Marcos J Guerrero-Muñoz,1,2 Rakez Kayed1–31Mitchell Center for Neurodegenerative Diseases, 2Departments of Neurology, Neuroscience, and Cell Biology, 3Sealy Center for Vaccine Development, University of Texas Medical Branch, Galveston, TX, USAAbstract: Alzheimer's disease (AD) is characterized by the presence of amyloid plaques composed mainly of amyloid-β (Aβ) protein. Overproduction or slow clearance of Aβ initiates a cascade of pathologic events that may lead to formation of neurofibrillary tangles, neuronal cell death, and dementia. …”
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Selective suppression of oligodendrocyte-derived amyloid beta rescues neuronal dysfunction in Alzheimer's disease. by Rikesh M Rajani, Robert Ellingford, Mariam Hellmuth, Samuel S Harris, Orjona S Taso, David Graykowski, Francesca Kar Wey Lam, Charles Arber, Emre Fertan, John S H Danial, Matthew Swire, Marcus Lloyd, Tatiana A Giovannucci, Mathieu Bourdenx, David Klenerman, Robert Vassar, Selina Wray, Carlo Sala Frigerio, Marc Aurel Busche

“…Reduction of amyloid beta (Aβ) has been shown to be effective in treating Alzheimer's disease (AD), but the underlying assumption that neurons are the main source of pathogenic Aβ is untested. …”
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Dichlorodiphenyltrichloroethane Impairs Amyloid Beta Clearance by Decreasing Liver X Receptor α Expression by Dongmei Wu, Yang Hu, Min Song, Gongbo Li

Subjects: “…amyloid beta…”
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A New Strategy in Epilepsy Therapy Through Attenuation of Phosphorylated Tau and Amyloid-beta by Junaidi Khotib, Badzlina Azyyati Maizan

Subjects: “…amyloid-beta peptides…”
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Zinc Metalloproteinases and Amyloid Beta-Peptide Metabolism: The Positive Side of Proteolysis in Alzheimer's Disease by Mallory Gough, Catherine Parr-Sturgess, Edward Parkin

“…Alzheimer's disease is a neurodegenerative condition characterized by an accumulation of toxic amyloid beta- (A𝛽-)peptides in the brain causing progressive neuronal death. …”
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Chronic cladribine administration increases amyloid beta peptide generation and plaque burden in mice. by Crystal D Hayes, Debleena Dey, Juan Pablo Palavicini, Hongjie Wang, Wataru Araki, Madepalli K Lakshmana

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Oligomeric and fibrillar amyloid beta 42 induce platelet aggregation partially through GPVI by O. Elaskalani, I. Khan, M. Morici, C. Matthysen, M. Sabale, R. N. Martins, G. Verdile, P. Metharom

Subjects: “…amyloid beta…”
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The Correlations Between Plasma Fibrinogen With Amyloid-Beta and Tau Levels in Patients With Alzheimer’s Disease by Dong-Yu Fan, Hao-Lun Sun, Hao-Lun Sun, Pu-Yang Sun, Jie-Ming Jian, Wei-Wei Li, Ying-Ying Shen, Fan Zeng, Yan-Jiang Wang, Xian-Le Bu

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Quantitative in vivo assessment of amyloid-beta phagocytic capacity in an Alzheimer’s disease mouse model by Shun-Fat Lau, Wei Wu, Heukjin Seo, Amy K.Y. Fu, Nancy Y. Ip

“…Summary: Alzheimer’s disease is characterized by the deposition of extracellular amyloid-beta (Aβ) plaques. While microglial phagocytosis is a major mechanism through which Aβ is cleared, there is no method for quantitatively assessing Aβ phagocytic capacity of microglia in vivo. …”
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Amyloid Beta-Related Alterations to Glutamate Signaling Dynamics During Alzheimer’s Disease Progression by Caleigh A. Findley, Andrzej Bartke, Kevin N. Hascup, Erin R. Hascup

“…AD pathology hallmarks include accumulation of senile plaques and neurofibrillary tangles; however, evidence supports that soluble amyloid beta (Aβ), rather than insoluble plaques, may instigate synaptic failure. …”
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Altered metamemory precedes cognitive impairment in subjective cognitive decline with positive amyloid-beta by QinJie Li, Feng-Feng Pan, Qi Huang, Chun-Yi Zac Lo, Fang Xie, QiHao Guo

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NMDA-receptor activation but not ion flux is required for amyloid-beta induced synaptic depression. by Albert Tamburri, Anthony Dudilot, Sara Licea, Catherine Bourgeois, Jannic Boehm

“…There is considerable evidence supporting the involvement of oligomeric amyloid-beta (Aβ) in the etiology of Alzheimer's disease. …”
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Verbenalin Reduces Amyloid-Beta Peptide Generation in Cellular and Animal Models of Alzheimer’s Disease by Juhee Lim, Seokhee Kim, Changhyun Lee, Jeongwoo Park, Gabsik Yang, Taehan Yook

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Comparative analysis of multimodal biomarkers for amyloid-beta positivity detection in Alzheimer's disease cohorts by Mostafa Mehdipour Ghazi, Per Selnes, Per Selnes, Santiago Timón-Reina, Sandra Tecelão, Silvia Ingala, Atle Bjørnerud, Atle Bjørnerud, Bjørn-Eivind Kirsebom, Bjørn-Eivind Kirsebom, Tormod Fladby, Tormod Fladby, Mads Nielsen

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