Behavioral Effects and Analgesic Profile of Hemoglobin-Derived Valorphin and Its Synthetic Analog in Rodents by Petar Todorov, Borislav Assenov, Dimo Angelov, Elena Dzhambazova, Daniela Pechlivanova

“…The results characterize valorphin and its derivative as promising analgesics that exert their effects both centrally and peripherally, without causing severe behavioral changes in experimental animals. …”
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Analgesic effects of dexmedetomidine and remifentanil on periprocedural pain during percutaneous ablation of renal carcinoma by Egidijus Semenas, Maria Lönnemark, Pär Dahlman, Michael Hultström, Mats Eriksson

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Analgesic effect of hydroalcoholic extract of Zingiber and piper nigrum in mice by tail-flick test by M.R H EIDARI, F Sharififar, M Salmani-Befrouei

“…(p<0.01) and 60min after injection (p<0.05).the results from the experiment of zingiber showed that the injection of perculated extract of zingiber to mice with doses of 50,75 and 100 mg/kg induced significant analgesia at 30,45,60 min(p<0.01) and 90min (p<0.05) post-injection in comparison with the control group.this response reached maximum at 45 min post-injection and reduced there after.injection of suxhleted extract with doses of 100mg/kg induced lower analgesic effect than the same dose of perculated extract at 45 min after the injection(p<0.01).at the other times,analgesic responses between the extracts were not significantly different.…”
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Local analgesic effect of tramadol is not mediated by opioid receptors in early postoperative pain in rats by Angela Maria Sousa, Hazem Adel Ashmawi

“…Background and objectives: Tramadol is known as a central acting analgesic drug, used for the treatment of moderate to severe pain. …”
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Drug-Nutraceutical Co-Crystal and Salts for Making New and Improved Bi-Functional Analgesics by Oli Abate Fulas, André Laferrière, Ghada Ayoub, Dayaker Gandrath, Cristina Mottillo, Hatem M. Titi, Robin S. Stein, Tomislav Friščić, Terence J. Coderre

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Drug Disease Interactions: Role of Inflammatory Mediators in Pain and Variability in Analgesic Drug Response by Kenneth M. Kulmatycki, Fakhreddin Jamali

“…Despite considerable knowledge in this area, analgesics may provide pain complete relief in only one out of five patients. …”
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Comparing Early Postoperative Period Analgesic Effect of Dexketoprofene Trometamol and Lornoxicam in Mediastinoscopy Cases by Gonul Sagiroglu

“…Objective: In this study, we aimed comparing early postoperative period analgesic effectiveness and the effects on opioid consumption of intravenous dexketoprofen and lornoxicam that are given preemptively. …”
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Analgesic and Anticancer Activity of Benzoxazole Clubbed 2-Pyrrolidinones as Novel Inhibitors of Monoacylglycerol Lipase by Obaid Afzal, Abdulmalik Saleh Alfawaz Altamimi, Mir Mohammad Shahroz, Hemant Kumar Sharma, Yassine Riadi, Md Quamrul Hassan

Subjects: “…analgesic…”
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Leaves extract of Murraya Koenigii linn for anti--inflammatory and analgesic activity in animal models by Shailly Gupta, Mathew George, Manmohan Singhal, Ganesh N Sharma, Vikas Garg

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Chemical composition and potential antioxidant, anti-inflammatory, and analgesic efficacy of Cistus albidus L. by Zouhri Aziz, Bouddine Toufik, Menyiy Naoual El, El-Mernissi Yahya, Laaroussi Hassan, Chebaibi Mohamed, Amhamdi Hassan, Elharrak Abdelhay, Nafidi Hiba-Allah, Sitotaw Baye, Jardan Yousef A. Bin, Bourhia Mohammed, Hajji Lhoussain

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Refinement of the motorised laminectomy-assisted rat spinal cord injury model by analgesic treatment by Harikrishnan Vijayakumar Sreelatha, Hamza Palekkodan, Ansar Fasaludeen, Lissy K. Krishnan, Klas S. P. Abelson

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Evaluation of analgesic and anti-inflammatory activity of a combination of tramadol-ibuprofen in experimental animals by Chidambarann Suthakaran, Muniyagounder K Kayalvizhi, Karnam Nithya, Thozhudalangudy AR Raja

“…Results and Conclusion: Combined use of tramadol and ibuprofen provided enhanced analgesic and anti-inflammatory effects in animal models of pain and inflammation.…”
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Analgesic agents administered by ambulance personnel to mountain bikers and hikers on trails in Western Australia by Paul J. Braybrook, Hideo Tohira, Deon Brink, Judith Finn, Peter L. Buzzacott

“…Objective: To describe the types of analgesic medications administered to patients who were attended by ambulance on recreational trails while mountain biking or hiking and report on the reduction in pain by these agents. …”
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Analgesic efficacy and safety of duloxetine premedication in patients undergoing hysterectomy – A systematic review by Abhijit Nair, Manish Thakre, Manamohan Rangaiah, Ujjwalraj Dudhedia, Nitinkumar Borkar

“…Background and Aims: Patients undergoing hysterectomy by open or laparoscopic approach experience moderate to severe postoperative pain. A multimodal analgesic approach is recommended for these patients. …”
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Assessment of the anti-inflammatory and analgesic effects of Opuntia ficus indica L. Cladodes extract by Abdelkader Ammam, Hafidh Zemour, M’hamed Kaid, Didier Villemin, Walid Soufan, Fathi Abdellatif Belhouadjeb

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Analgesics in rheumatic diseases – a necessary component of therapy aimed at improving the quality of life by A. E. Karateev

“…Control of chronic pain is one of the main elements of the complex therapy of rheumatic diseases (RD). The use of analgesics is of fundamental importance for the management of patients with osteoarthritis (OA), since a unified system of pathogenetic therapy has not yet been developed for this disease. …”
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Potential analgesic effect of Foshousan oil-loaded chitosan-alginate nanoparticles on the treatment of migraine by Yulong Chen, Qingzhou Cheng, Shan Zeng, Site Lv

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Mechanisms and implications in gene polymorphism mediated diverse reponses to sedatives, analgesics and muscle relaxants by Yan Sun, Hongyu Zhu, Elham Esmaeili, Xue Tang, Zhilin Wu

Subjects: “…analgesics…”
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Refinement of the motorised laminectomy-assisted rat spinal cord injury model by analgesic treatment. by Harikrishnan Vijayakumar Sreelatha, Hamza Palekkodan, Ansar Fasaludeen, Lissy K Krishnan, Klas S P Abelson

“…It was concluded that the usage of analgesia improved animal wellbeing while having no effects on the functional aspects of the animal model in comparison to the animals that received no analgesics.…”
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Comparison of antioxidant and analgesic effects of gallic acid and metformin in streptozotocin-induced hyperglycemic rats by Fatemeh Nohtani, Morteza Behnam Rasouli, Masumeh Kheirabadi

Subjects: “…analgesic…”
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