Compression of the Analgesic Effects of Intravenous Metoclopramide and Ondansetron in combination on Renal Colic in the Patients receiving Morphine by mohammadali jafari nodoushan, soheila azimi abarghouei, faeze zeinali nasrabadi, ali raee ezzabadi, naser mohammad karimi, mohammadreza kazemi

“…Background and Aim: The aim of this study was to compare the analgesic effects of I.V. ondansetron and I.V. metoclopramide in combination with morphine in relieving pain in the patients with acute renal colic receiving morphine in the emergency department. …”
Get full text

Thermal study of active pharmaceutical ingredients used as analgesics by DTA and DSC coupled to photovisual system by Laianne Carla B. Alencar, Cleildo P. Santana, Karla Monik A. Silva, Fernanda P. Nóbrega, Lidiane P. Correia, Widson M. Santos, Fabrício Havy D. Andrade, Fábio S. Santos, Rui Oliveira Macêdo, Ana Cláudia D. Medeiros

“…The aim of this work was to evaluate the compatibility between dipyrone, caffeine and orphenadrine citrate, active pharmaceutical ingredients (APIs) commonly used in fixed-dose combination (FDC) in analgesic medicines. The APIs were analyzed by Differential Scanning Calorimetry (DSC), Differential Thermal Analysis (DTA), Fourier Transform Infrared Spectroscopy (FTIR) and X-Ray Powder Diffraction (XRPD). …”
Get full text

Antibiotic and analgesic residues in the environment – Occurrence and ecological risk study from the Sunyani municipality, Ghana by Bernice Araba Otoo, Ivy Anima Amoabeng, Godfred Darko, Lawrence Sheringham Borquaye

“…The maximum concentration of analgesics in liquid samples analyzed was 3.20 mg/L (paracetamol) and 3.00 mg/kg (caffeine) in soil samples. …”
Get full text

Intradermal methylene blue analgesic application in posthemorrhoidectomy pain management: a randomized controlled trial by Ramin Azhough, Pooya Jalali, Mohammad Reza Dashti, Sahar Taher, Ali Aghajani, Ali Aghajani

“…Methylene blue group reported significantly lower postoperative pain scores from days 1 to 7, with no significant differences afterward.ConclusionThis ongoing randomized controlled trial reveals the potential analgesic benefits of intradermal injection 1% methylene blue. …”
Get full text

Annexin A1 exerts analgesic effect in a mouse model of medication overuse headache by Zihua Gong, Chunxiao Yang, Wei Dai, Shuai Miao, Yingyuan Liu, Zhiyang Jiao, Bozhi Li, Wei Xie, Wei Zhao, Xun Han, Shengyuan Yu, Zhao Dong

“…These results suggest that ANXA1 may have an analgesic effect in triptan-associated MOH and could potentially serve as a therapeutic target.…”
Get full text

Evaluation of the anti-inflammatory, analgesic, anti-pyretic and anti-ulcerogenic potentials of synthetic indole derivatives by Saira Siddique, Khawaja Raees Ahmad, Syed Kashif Nawaz, Syeda Nadia Ahmad, Rabiyah Ali, Iram Inayat, Sadia Suleman, Muhammad Ali Kanwal, Muhammad Usman

“…In the present study, some synthetic indole derivatives are used to check anti-inflammatory, analgesic, antipyretic and gastroprotective activity in albino mice. …”
Get full text

Analgesic effect of intra-articular ropivacaine injection after arthroscopic surgery on the shoulder joint in dogs by J.H. Kim, S.H. Seok, T.Y. Park, H.J. Kim, J.M. Kim, S.W. Lee, H.C. Lee, S.C. Yeon

“…The present study was conducted to evaluate the analgesic effect of intra-articular injection of ropivacaine after arthroscopic surgery in dog shoulder joints. …”
Get full text

Chemical Characterization, Anti inflammatory and Analgesic Properties of <i>Jatropha Multifida</i> Root Bark by A Falodun, I Igbe, O Erharuyi, OJ Agbanyim

“…Multifida root bark has anti-inflammatory and analgesic activities which further substantiate its use in folk medicine.…”
Get full text

Formulation of Bioerodible Ketamine Microparticles as an Analgesic Adjuvant Treatment Produced by Supercritical Fluid Polymer Encapsulation by Felicity Y. Han, Andrew K. Whittaker, Steven M. Howdle, Andrew Naylor, Anjumn Shabir-Ahmed, Cheng Zhang, Maree T. Smith

Subjects: “…analgesic adjuvant…”
Get full text

Evaluation of transanesthetic complications comparing epidural versus analgesic continuous infusion in dogs submitted to neurosurgeries by Lícia Flávia Silva Herculano, Jessika Schopf Pasini, Victor Reis Galindo, Charline Vanessa Vaccarin, Alexandre Mazzanti, André Vasconcelos Soares

“…Neurosurgeries have become more frequent in veterinary hospitals, however, there are some questions regarding anesthetics protocols and analgesic techniques. Thus, patient analgesia and hemodynamic stability play a key role in pre, post, and perioperative moments favoring an adequate recovery. …”
Get full text

Expression of Concern: Prediction Formulas for Individual Opioid Analgesic Requirements Based on Genetic Polymorphism Analyses

Get full text

Analgesic Efficacy of COX-2 Inhibitors in Periodontal Surgery: A Systematic Review and Meta-Analysis by Mario Alberto Isiordia-Espinoza, Eduardo Gómez-Sánchez, Itzel Joselyn Mora-Falcón, Iván Agustín Amador-Beas, Adriana Hernández-Gómez, Nicolás Addiel Serafín-Higuera, Lorenzo Franco-de la Torre

Subjects: “…analgesic efficacy…”
Get full text

Brain Distribution and Metabolism of Flupirtine, a Nonopioid Analgesic Drug with Antiseizure Effects, in Neonatal Rats by Madhoosudan A. Patil, Brock A. Matter, Yogendra H. Raol, David W. A. Bourne, Ryan A. Kelley, Uday B. Kompella

“…Flupirtine, a nonopioid analgesic drug, is effective in treating neonatal seizures. …”
Get full text

Topical Delivery Systems Effectively Transport Analgesics to Areas of Localized Pain via Direct Diffusion by Thomas Birngruber, Kip Vought, Simon Schwingenschuh, Peter Reisenegger, Howard Maibach, Dmitri Lissin

Subjects: Get full text

Correlation between FLACC scale score and analgesic requirement in children undergoing Minimally Invasive Surgery by Assunta Turco, Mariapina Cerulo, Fulvia Del Conte, Vincenzo Coppola, Giovanni Severino, Maria Escolino, Ciro Esposito

“…In each patient were analyzed the correlation between FLACC score and analgesic requirement. Pain evaluation was assigned immediately after surgery and at 15 and 60 minutes. 36.6% of patients (56 children) were asleep so considered pain free; 21.6% of patients (33 children) had a FLACC score more than 7 so they required analgesics and the pain assessment 15 and 60 minutes after was significantly lower. 41.8% of patients (64 children) had a postoperative FLACC score less than 3, so they didn’t require any analgesic treatment. …”
Get full text

Use of analgesic and anti-inflammatory drugs before assistance in a children's first aid unit by Camila Nogueira Prolungatti, Rita de Cássia da Silva Rodrigues Garcia, Silvia Maira Pereira Cintra, Rosemeire Isabel Ramos Análio, Oscar César Pires

Subjects: “…Analgesics…”
Get full text

Impact of hydroxyurea on hospital stay & analgesic utilization in sickle cell anaemia with vaso-occlusive crises by Uttam Kumar Soren, Pradeep Kumar Mohanty, Satyabrata Meher, Sunil Kumar Sukla, Mrutyunjay Hiregoudar

Subjects: “…analgesics - hospital stay - hydroxyurea - sickle cell anaemia - vaso-occlusive crises…”
Get full text

Phytochemical Screening, Acute Toxicity and Analgesic Activity of Extracts From Newbouldia laevis in Laboratory Animals by Odo Peter, Odo Ekene, Ihemadu Chiaguguom, Felix Grace, Nwaubani Daniel, Amako Ngozi, Omekara Israel

“…Statistical analysis; P>0.05 confidence level, methanol fraction recorded highest analgesic activities while ethylacetate fraction had least.…”
Get full text

The Impact of P-Glycoprotein on Opioid Analgesics: What’s the Real Meaning in Pain Management and Palliative Care? by Flaminia Coluzzi, Maria Sole Scerpa, Monica Rocco, Diego Fornasari

Get full text

Modulation of NMDA receptor activity by CR4056, an imidazoline-2 receptor ligand with analgesic properties by Giulia Puja, Gabriele Losi, Lucio Rovati, Marco Lanza, Gianfranco Caselli, Rita Bardoni

“…CR4056 is an imidazoline-2 receptor ligand having potent analgesic activity and synergistic effect with opioids. …”
Get full text