Towards automatic scoring of spinal x-ray for ankylosing spondylitis by Mo, Y, Chen, Y, Readie, A, Ligozio, G, Coroller, T, Papiez, BW

“…Manually grading structural changes with the modified Stoke Ankylosing Spondylitis Spinal Score (mSASSS) on spinal X-ray imaging is costly and timeconsuming due to bone shape complexity and image quality variations. …”

Susceptibility to ankylosing spondylitis in twins: the role of genes, HLA, and the environment. by Brown, M, Kennedy, L, MacGregor, A, Darke, C, Duncan, E, Shatford, J, Taylor, A, Calin, A, Wordsworth, B

“…OBJECTIVE: To determine the relative effects of genetic and environmental factors in susceptibility to ankylosing spondylitis (AS). METHODS: Twins with AS were identified from the Royal National Hospital for Rheumatic Diseases database. …”

Discovery of candidate serum proteomic and metabolomic biomarkers in ankylosing spondylitis. by Fischer, R, Trudgian, D, Wright, C, Thomas, G, Bradbury, L, Brown, M, Bowness, P, Kessler, B

“…Ankylosing Spondylitis (AS) is a common inflammatory rheumatic disease with a predilection for the axial skeleton, affecting 0.2% of the population. …”

Genetic aspects of susceptibility, severity, and clinical expression in ankylosing spondylitis. by Brown, M, Crane, A, Wordsworth, B

“…While twin studies have previously demonstrated high heritability of susceptibility to ankylosing spondylitis (AS), it is only recently that the involvement of genetic factors in determining the severity of the disease has been demonstrated. …”

INVESTIGATING THE ROLE OF ENDOPLASMIC RETICULUM AMINOPEPTIDASE-1 IN ANKYLOSING SPONDYLITIS by Chen, L, Fisher, R, Kollnberger, S, Shastri, N, Kessler, B, Bowness, P

Ankylosing spondylitis without B27: no evidence for gene conversion. by Pease, C, Ellis, SA, Mcmichael, A, Brewerton, D

“…Isoelectric focusing gel electrophoresis was used to look for variant HLA molecules in five patients with HLA-B27 negative ankylosing spondylitis (AS). The isoelectric points of the HLA-A and B antigens from these patients and HLA paired controls were identical. …”

Towards defining the genetic determinants of disease severity in ankylosing spondylitis. by Brophy, S, Hamersma, J, Bradbury, L, Timms, A, Edwards, S, Laval, S, Wordsworth, B, Cardon, L, Calin, A, Brown, M

Towards defining the genetic determinants of disease severity in ankylosing spondylitis by Brophy, S, Hamersma, J, Bradbury, L, Timms, A, Edwards, S, Laval, S, Wordsworth, B, Calin, A, Brown, M

The effect of HLA-DR genes on susceptibility to and severity of ankylosing spondylitis. by Brown, M, Kennedy, L, Darke, C, Gibson, K, Pile, K, Shatford, J, Taylor, A, Calin, A, Wordsworth, B

“…OBJECTIVE: To analyze the effect of HLA-DR genes on susceptibility to and severity of ankylosing spondylitis (AS). METHODS: Three hundred sixty-three white British AS patients were studied; 149 were carefully assessed for a range of clinical manifestations, and disease severity was assessed using a structured questionnaire. …”

Exploring the role of GPR65 in driving the pathology of ankylosing spondylitis by Barrett, J

“…<p>Genome wide association studies have identified GPR65 risk loci with many immune-mediated diseases, including ankylosing spondylitis; however, its pathogenic role remains unknown. …”

Familial versus sporadic ankylosing spondylitis. two different diseases? by Calin, A, Gail Kennedy, L, Edmunds, L, Will, R

“…<strong>Objective:</strong> To define potential differences and the possible contribution of susceptibility or severity genes in familial versus sporadic ankylosing spondylitis (AS). <strong>Methods:</strong> Three hundred twenty patients with AS were studied: 160 who had first-degree relatives with AS (familial) and 160 age- and sex-matched controls who had no first-degree relative with the disease (sporadic). …”

Identification of major loci controlling clinical manifestations of ankylosing spondylitis. by Brown, M, Brophy, S, Bradbury, L, Hamersma, J, Timms, A, Laval, S, Cardon, L, Calin, A, Wordsworth, B

“…Traits assessed were age at symptom onset, disease activity assessed by the Bath Ankylosing Spondylitis Disease Activity Index (BASDAI), and functional impairment assessed by the Bath Ankylosing Spondylitis Functional Index (BASFI). …”

MAPPING THE NON-B27 MHC ASSOCIATIONS OF ANKYLOSING SPONDYLITIS (AS) by Sims, A, Bernardo, M, Broxholme, J, Herzberg, I, Bradbury, L, Callin, A, Wordsworth, B, Darke, C, Brown, M

A genome-wide screen for susceptibility loci in ankylosing spondylitis. by Brown, M, Pile, K, Kennedy, L, Campbell, D, Andrew, L, March, R, Shatford, J, Weeks, D, Calin, A, Wordsworth, B

“… OBJECTIVE: To localize the regions containing genes that determine susceptibility to ankylosing spondylitis (AS). METHODS: One hundred five white British families with 121 affected sibling pairs with AS were recruited, largely from the Royal National Hospital for Rheumatic Diseases AS database. …”

Adalimumab reduces pain, fatigue, and stiffness in patients with ankylosing spondylitis: results from the adalimumab trial evaluating long-term safety and efficacy for ankylosing spondylitis (ATLAS). by Revicki, D, Luo, M, Wordsworth, P, Wong, R, Chen, N, Davis, J

“… OBJECTIVE: To evaluate the effect of adalimumab on pain, fatigue, and stiffness in patients with active ankylosing spondylitis (AS). METHODS: The Adalimumab Trial Evaluating Long-Term Safety and Efficacy for Ankylosing Spondylitis (ATLAS) was an ongoing 5-year study that included an initial 24-week, randomized, placebo-controlled, double-blind period. …”

A case of severe ankylosing spondylitis posted for hip replacement surgery by Nalini Kotekar, N V Nagalakshmi, Gururaj, Mujeeb Rehman

Subjects: “…Ankylosing spondylitis; Patient positioning; ′Bamboo spine′; Difficult intubation…”
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Real-world data on secukinumab use for psoriatic arthritis and ankylosing spondylitis by Ashley Elliott, Gary Wright

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COMPARATIVE EVALUATION OF PATIENTS WITH ANKYLOSING SPONDYLITIS AND NON-RADIOGRAPHIC AXIAL SPONDYLOARTHRITIS by I. А. Cherentsova, E. N. Otteva, A. B. Ostrovsky

Subjects: “…ankylosing spondylitis…”
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Early signs of myocardial dysfunction in patients with rheumatoid arthritis and ankylosing spondylitis by L. I. Feiskhanova, D. I. Abdulganieva

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Pregnancy in ankylosing spondylitis: the view of a female patient and a physician by Z. M. Gandaloeva, O. A. Krichevskaya, S. I. Glukhova, T. V. Dubinina, A. M. Lila

“…Objective: to study the impact of the diagnosis of ankylosing spondylitis (AS) on the planning of pregnancy by patients and their attitude towards the use of drugs during gestation and to assess the competency of physicians in the issues relating to pregnancy in AS.Patients and methods. …”
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