Can avoidance of complications lead to biased healthcare decisions? by Jennifer Amsterlaw, Brian J. Zikmund-Fisher, Angela Fagerlin, Peter A. Ubel

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Monocyte Toll-like Receptor 4 Signaling Is Essential for Post Thrombotic Urokinase Expression by Sriganesh Sharma, Kiran Kumar, Sharika Bamezai, Oscar Yesid Moreno Rocha, Sabrina Rocco, Kevin Dale Mangum, Catherine Luke, Katherine A. Gallagher, Bethany Moore, Peter Henke, Andrea T. Obi

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730 Histotripsy focused ultrasound ablation induces immunological cell death in treated and distant untreated tumors by Clifford Cho, Tejaswi Worlikar, Anutosh Ganguly, Ryan Hubbard, Hannah Garavaglia, Joe Dib, Zhen Xu, Ashley Pepple, Reliza McGinnis, Amy Felsted, Joe Guy, Michal Olszewski

Development and Validation of a Scalable Next-Generation Sequencing System for Assessing Relevant Somatic Variants in Solid Tumors by Daniel H. Hovelson, Andrew S. McDaniel, Andi K. Cani, Bryan Johnson, Kate Rhodes, Paul D. Williams, Santhoshi Bandla, Geoffrey Bien, Paul Choppa, Fiona Hyland, Rajesh Gottimukkala, Guoying Liu, Manimozhi Manivannan, Jeoffrey Schageman, Efren Ballesteros-Villagrana, Catherine S. Grasso, Michael J. Quist, Venkata Yadati, Anmol Amin, Javed Siddiqui, Bryan L. Betz, Karen E. Knudsen, Kathleen A. Cooney, Felix Y. Feng, Michael H. Roh, Peter S. Nelson, Chia-Jen Liu, David G. Beer, Peter Wyngaard, Arul M. Chinnaiyan, Seth Sadis, Daniel R. Rhodes, Scott A. Tomlins

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Histone H3 K27M-mediated regulation of cancer cell stemness and differentiation in diffuse midline glioma by Monika Sharma, Ivana Barravecchia, Brian Magnuson, Sarah F. Ferris, April Apfelbaum, Nneka E. Mbah, Jeanette Cruz, Varunkumar Krishnamoorthy, Robert Teis, McKenzie Kauss, Carl Koschmann, Costas A. Lyssiotis, Mats Ljungman, Stefanie Galban

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Distinct mutational processes shape selection of MHC class I and class II mutations across primary and metastatic tumors by Michael B. Mumphrey, Noshad Hosseini, Abhijit Parolia, Jie Geng, Weiping Zou, Malini Raghavan, Arul Chinnaiyan, Marcin Cieslik

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Automated Synthesis of 18F-BCPP-EF {2-tert-Butyl-4-Chloro-5-{6-[2-(2[18F]fluoroethoxy)-Ethoxy]-Pyridin-3-ylmethoxy}-2H-Pyridazin-3-One for Imaging of Mitochondrial Complex 1 in Par... by Tanpreet Kaur, Allen F. Brooks, Katherine M. Liddell, Bradford D. Henderson, Brian G. Hockley, Nicolaas I. Bohnen, Nicolaas I. Bohnen, Nicolaas I. Bohnen, Nicolaas I. Bohnen, Roger L. Albin, Roger L. Albin, Roger L. Albin, Peter J. H. Scott

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Abstract 104: Identification of the Role of Sensory Nerve TrkA Signaling on Progenitor Cell Fate after Extremity Trauma by Charles Hwang, BS, David M. Stepien, MD, PhD, Carrie Kubiak, MD, Carolyn A. Meyers, BS, Seungyong Lee, PhD, Michael Sorkin, MD, Chase A. Pagani, BA, Talis Rehse, BS, Noelle D. Visser, MS, Mohamed A. Garada, Zaid N. Khatib, BS, Prasanth Kotha, Jeffrey Lisiecki, MD, Kaetlin Vasquez, MS, Paul S. Cederna, MD, Stephen W.P. Kemp, PhD, Thomas L. Clemens, PhD, Aaron W. James, MD, PhD, Benjamin Levi, MD

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Genomics driven precision oncology in advanced biliary tract cancer improves survival by Chandan Kumar-Sinha, Pankaj Vats, Nguyen Tran, Dan R. Robinson, Valerie Gunchick, Yi-Mi Wu, Xuhong Cao, Yu Ning, Rui Wang, Erica Rabban, Janice Bell, Sunita Shankar, Rahul Mannan, Yuping Zhang, Mark M. Zalupski, Arul M. Chinnaiyan, Vaibhav Sahai

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Unknown primary Merkel cell carcinoma in the immunosuppressed patient: Case series by Jason M. Rizzo, MD, PhD, Paul W. Harms, MD, PhD, Kelly L. Harms, MD, PhD, Andrew Plaska, MD, Chad Brenner, PhD, Alison B. Durham, MD

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Targeting Neuroinflammation in Brain Cancer: Uncovering Mechanisms, Pharmacological Targets, and Neuropharmaceutical Developments by Mahmoud S. Alghamri, Mahmoud S. Alghamri, Brandon L. McClellan, Brandon L. McClellan, Carson S. Hartlage, Carson S. Hartlage, Santiago Haase, Santiago Haase, Syed Mohd Faisal, Syed Mohd Faisal, Rohit Thalla, Rohit Thalla, Ali Dabaja, Ali Dabaja, Kaushik Banerjee, Kaushik Banerjee, Stephen V. Carney, Stephen V. Carney, Anzar A. Mujeeb, Anzar A. Mujeeb, Michael R. Olin, Michael R. Olin, James J. Moon, James J. Moon, James J. Moon, Anna Schwendeman, Anna Schwendeman, Pedro R. Lowenstein, Pedro R. Lowenstein, Pedro R. Lowenstein, Pedro R. Lowenstein, Maria G. Castro, Maria G. Castro, Maria G. Castro, Maria G. Castro

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Dose optimization of early high-dose valproic acid for neuroprotection in a swine cardiac arrest model by Cindy H. Hsu, Mohamad H. Tiba, Brendan M. McCracken, Carmen I. Colmenero, Zachary Pickell, Danielle C. Leander, Anne M. Weitzel, Sarita Raghunayakula, Jinhui Liao, Tulasi Jinka, Brandon C. Cummings, Manjunath P. Pai, Hasan B. Alam, Kevin R. Ward, Thomas H. Sanderson, Robert W. Neumar

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Galectin-3 Regulates Atrial Fibrillation Remodeling and Predicts Catheter Ablation Outcomes by Yoshio Takemoto, MD, PhD, Rafael J. Ramirez, PhD, Miki Yokokawa, MD, Kuljeet Kaur, PhD, Daniela Ponce-Balbuena, PhD, Mohamad C. Sinno, MD, B. Cicero Willis, MD, Hamid Ghanbari, MD, Steven R. Ennis, PhD, Guadalupe Guerrero-Serna, PhD, Bettina C. Henzi, MD, Rakesh Latchamsetty, MD, Roberto Ramos-Mondragon, PhD, Hassan Musa, PhD, Raphael P. Martins, MD, Sandeep V. Pandit, PhD, Sami F. Noujaim, PhD, Thomas Crawford, MD, Krit Jongnarangsin, MD, Frank Pelosi, MD, Frank Bogun, MD, Aman Chugh, MD, Omer Berenfeld, PhD, Fred Morady, MD, Hakan Oral, MD, José Jalife, MD

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RAI1 Regulates Activity-Dependent Nascent Transcription and Synaptic Scaling by Patricia M. Garay, Alex Chen, Takao Tsukahara, Jean Carlos Rodríguez Díaz, Rafi Kohen, J. Christian Althaus, Margarete A. Wallner, Roman J. Giger, Kevin S. Jones, Michael A. Sutton, Shigeki Iwase

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Hematopoietic stem and progenitor cells harbor provirus with identical Gag and V3 sequences as residual plasma virus in optimally treated patients by V.H. Terry, N.T. Sebastian, R. Yucha, F. Taschuk, L.A. McNamara, A. Onafuwa-Nuga, J. Riddell, IV, D. Bixby, K.L. Collins

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Single-cell RNA sequencing identifies hippocampal microglial dysregulation in diet-induced obesity by Rosemary E. Henn, Kai Guo, Sarah E. Elzinga, Mohamed H. Noureldein, Faye E. Mendelson, John M. Hayes, Diana M. Rigan, Masha G. Savelieff, Junguk Hur, Eva L. Feldman

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Running speed and REM sleep control two distinct modes of rapid interhemispheric communication by Megha Ghosh, Fang-Chi Yang, Sharena P. Rice, Vaughn Hetrick, Alcides Lorenzo Gonzalez, Danny Siu, Ellen K.W. Brennan, Tibin T. John, Allison M. Ahrens, Omar J. Ahmed

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Quantification and immunoprofiling of bladder cancer cell-derived extracellular vesicles with microfluidic chemiluminescent ELISA by Xiaotian Tan, Kathleen C. Day, Xuzhou Li, Luke J. Broses, Wen Xue, Weishu Wu, William Y. Wang, Ting-Wen Lo, Emma Purcell, Sicong Wang, Yun-Lu Sun, Maung Kyaw Khaing Oo, Brendon M. Baker, Sunitha Nagrath, Mark L. Day, Xudong Fan

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Metastatic same-site squamous cell carcinoma arising during vismodegib therapy for basal cell carcinoma by Raymond Zhao, BS, Bo Wang, MD, PhD, Lori Lowe, MD, Andrzej Dlugosz, MD, Christopher K. Bichakjian, MD

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54. ONE YEAR OUTCOMES AFTER REGENERATIVE PERIPHERAL NERVE INTERFACE SURGERY FOR POSTAMPUTATION PAIN: RESULTS OF A PROSPECTIVE CLINICAL TRIAL by Nishant Ganesh Kumar, MD, Carrie A. Kubiak, MD, Jennifer Hamill, MPH, Hyungjin M. Kim, Sc D, Melissa J. Tinney, MD, Randy S. Roth, PhD, Michael E. Geisser, PhD, Paul Cederna, MD, Stephen W.P. Kemp, PhD, Theodore A. Kung, MD

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