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    Epigenetic Profiling of Type 2 Diabetes Mellitus: An Epigenome-Wide Association Study of DNA Methylation in the Korean Genome and Epidemiology Study by Hyein Seo, Jae-Ho Park, Jin-Taek Hwang, Hyo-Kyoung Choi, Soo-Hyun Park, Jangho Lee

    Published 2023-12-01
    “…In this study, we explored the epigenetic landscape of diabetes using data from the Korean Genome and Epidemiology Study (KoGES), specifically the Ansung–Ansan (AS–AS) cohort. Using epigenome-wide association studies, we investigated DNA methylation patterns in patients with type 2 diabetes mellitus (T2DM) and those with normal glucose regulation. …”
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    Association of Plant-Based and High-Protein Diets with a Lower Obesity Risk Defined by Fat Mass in Middle-Aged and Elderly Persons with a High Genetic Risk of Obesity by James W. Daily, Sunmin Park

    Published 2023-02-01
    “…We utilized a genome-wide association study to identify genetic variants associated with high fat mass (obesity; <i>n</i> = 10,502) and combined them to generate polygenic risk scores (PRS) of genetic variants interacting with each other in adults aged over 40 while excluding body-fat-related diseases in a city-hospital-based cohort (<i>n</i> = 53,828). It was validated in Ansan/Ansung plus rural cohorts (<i>n</i> = 13,007). …”
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    Association of NAFLD with FGF21 Polygenic Hazard Score, and Its Interaction with Protein Intake Level in Korean Adults by Hae Jin Lee, Jinyoung Shon, Yoon Jung Park

    Published 2023-05-01
    “…Data on 3501 participants of the Korean Genome Epidemiology Study (Ansan–Ansung) were analyzed. Eight single-nucleotide polymorphisms of fibroblast growth factor receptors and beta-klotho were selected for PHS determination using forward stepwise analysis. …”
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