AMPA and GABAA receptor nanodomains assemble in the absence of synaptic neurotransmitter release by Harrison J. Ramsay, Sara E. Gookin, Austin M. Ramsey, Dean J. Kareemo, Kevin C. Crosby, Dominik G. Stich, Samantha S. Olah, Hannah S. Actor-Engel, Katharine R. Smith, Matthew J. Kennedy

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LRMP inhibits cAMP potentiation of HCN4 channels by disrupting intramolecular signal transduction by Colin H Peters, Rohit K Singh, Avery A Langley, William G Nichols, Hannah R Ferris, Danielle A Jeffrey, Catherine Proenza, John R Bankston

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Distinct roles of PIK3CA in the enrichment and maintenance of cancer stem cells in head and neck squamous cell carcinoma by Xi Chen, Yu Cao, Wafik Sedhom, Ling Lu, Yanqiu Liu, Haibo Wang, Masako Oka, Sophia Bornstein, Sherif Said, John Song, Shi‐Long Lu

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Neonatal ketamine exposure impairs infrapyramidal bundle pruning and causes lasting increase in excitatory synaptic transmission in hippocampal CA3 neurons by Omar Hoseá Cabrera, Nemanja Useinovic, Stefan Maksimovic, Michelle Near, Nidia Quillinan, Slobodan M. Todorovic, Vesna Jevtovic-Todorovic

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Emicizumab initiation and bleeding outcomes in people with hemophilia A with and without inhibitors: A single‐center report by Beth Boulden Warren, Adrian Chan, Marilyn Manco‐Johnson, Brian R. Branchford, Tyler W. Buckner, Genevieve Moyer, Elizabeth Gibson, Dianne Thornhill, Michael Wang, Christopher J Ng

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CPT1A Over-Expression Increases Reactive Oxygen Species in the Mitochondria and Promotes Antioxidant Defenses in Prostate Cancer by Molishree Joshi, Jihye Kim, Angelo D’Alessandro, Emily Monk, Kimberley Bruce, Hanan Elajaili, Eva Nozik-Grayck, Andrew Goodspeed, James C. Costello, Isabel R. Schlaepfer

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A tyrosine kinase inhibitor-induced interferon response positively associates with clinical response in EGFR-mutant lung cancer by Natalia J. Gurule, Caroline E. McCoach, Trista K. Hinz, Daniel T. Merrick, Adriaan Van Bokhoven, Jihye Kim, Tejas Patil, Jacob Calhoun, Raphael A. Nemenoff, Aik Choon Tan, Robert C. Doebele, Lynn E. Heasley

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High-Throughput Mechanistic Screening of Epigenetic Compounds for the Potential Treatment of Meningiomas by Philip D. Tatman, Tadeusz H. Wroblewski, Anthony R. Fringuello, Samuel R. Scherer, William B. Foreman, Denise M. Damek, Kevin Lillehei, A. Samy Youssef, Randy L. Jensen, Michael W. Graner, D. Ryan Ormond

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Multifaceted immune dysregulation characterizes individuals at-risk for rheumatoid arthritis by Eddie A. James, V. Michael Holers, Radhika Iyer, E. Barton Prideaux, Navin L. Rao, Cliff Rims, Virginia S. Muir, Sylvia E. Posso, Michelle S. Bloom, Amin Zia, Serra E. Elliott, Julia Z. Adamska, Rizi Ai, R. Camille Brewer, Jennifer A. Seifert, LauraKay Moss, Saman Barzideh, M. Kristen Demoruelle, Christopher C. Striebich, Yuko Okamoto, Enkhtsogt Sainbayar, Alexandra A. Crook, Ryan A. Peterson, Lauren A. Vanderlinden, Wei Wang, David L. Boyle, William H. Robinson, Jane H. Buckner, Gary S. Firestein, Kevin D. Deane

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Fatty Acid Ethyl Ethers: New Modulators of Acute Ethanol-Mediated Hepatotoxicity? by Paige Anton, BS, Lauren N. Rutt, MS, Shannon M. Twardy, MS, Rebecca L. McCullough, PhD

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Curcumin therapy to treat vascular dysfunction in children and young adults with autosomal dominant polycystic kidney disease: Design and baseline characteristics of participants by Kristen L. Nowak, Heather Farmer-Bailey, Melissa A. Cadnapaphornchai, Zhiying You, Diana George, Wei Wang, Anna Jovanovich, Danielle E. Soranno, Berenice Gitomer, Michel Chonchol

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From circuits to behavior: Amygdala dysfunction in fragile X syndrome by Matthew N. Svalina, Matthew N. Svalina, Matthew N. Svalina, Matthew N. Svalina, Regina Sullivan, Regina Sullivan, Diego Restrepo, Diego Restrepo, Molly M. Huntsman, Molly M. Huntsman, Molly M. Huntsman

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Apolipoprotein A-I, elevated in trauma patients, inhibits platelet activation and decreases clot strength by Wilbert L. Jones, Christopher R. Ramos, Anirban Banerjee, Ernest E. Moore, Kirk C. Hansen, Julia R. Coleman, Marguerite Kelher, Keith B. Neeves, Christopher C. Silliman, Jorge Di Paola, Brian Branchford

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An Improved High Yield Total Synthesis and Cytotoxicity Study of the Marine Alkaloid Neoamphimedine: An ATP-Competitive Inhibitor of Topoisomerase IIα and Potent Anticancer Agent by Linfeng Li, Adedoyin D. Abraham, Qiong Zhou, Hadi Ali, Jeremy V. O'Brien, Brayden D. Hamill, John J. Arcaroli, Wells A. Messersmith, Daniel V. LaBarbera

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NPC1 Confers Metabolic Flexibility in Triple Negative Breast Cancer by Kathleen I. O’Neill, Li-Wei Kuo, Michelle M. Williams, Hanne Lind, Lyndsey S. Crump, Nia G. Hammond, Nicole S. Spoelstra, M. Cecilia Caino, Jennifer K. Richer

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Preferences and Insights for Participation in a Rheumatoid Arthritis Clinical Prevention Trial: A Mixed‐Methods Study by Chelsie L. Fleischer, Elizabeth A. Bemis, Marie L. Feser, Vasilisa A. Kormendi, Alvina Zhang, Katherine Ketcham, Sharon D. White, Christopher C. Striebich, Kevin D. Deane, Mark Harrison

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Acute Kidney Injury in Pediatric Diabetic Kidney Disease by Federica Piani, Federica Piani, Federica Piani, Trenton Reinicke, Claudio Borghi, Kalie L. Tommerdahl, Kalie L. Tommerdahl, Gabriel Cara-Fuentes, Gabriel Cara-Fuentes, Richard J. Johnson, Petter Bjornstad, Petter Bjornstad

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CCR4‐IL2 bispecific immunotoxin is more effective than brentuximab for targeted therapy of cutaneous T‐cell lymphoma in a mouse CTCL model by Zhaohui Wang, Jihong Ma, Huiping Zhang, Rashmi Ramakrishna, Danielle Mintzlaff, David W. Mathes, Elizabeth A. Pomfret, M. Scott Lucia, Dexiang Gao, Bradley M. Haverkos, Zhirui Wang

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A novel diphtheria toxin‐based bivalent human EGF fusion toxin for treatment of head and neck squamous cell carcinoma by Zeng Qi, Yue Qiu, Zhaohui Wang, Huiping Zhang, Ling Lu, Yanqiu Liu, David Mathes, Elizabeth A. Pomfret, Dexiang Gao, Shi‐Long Lu, Zhirui Wang

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Overcoming doxorubicin resistance in triple-negative breast cancer using the class I-targeting HDAC inhibitor bocodepsin/OKI-179 to promote apoptosis by Stephen G. Smoots, Anna R. Schreiber, Marilyn M. Jackson, Stacey M. Bagby, Adrian T A. Dominguez, Evan D. Dus, Cameron A. Binns, Morgan MacBeth, Phaedra A. Whitty, Jennifer R. Diamond, Todd M. Pitts

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