The worldwide Antibiotic Resistance and Prescribing in European Children (ARPEC) point prevalence survey: developing hospital-quality indicators of antibiotic prescribing for children by Versporten, A, Bielicki, J, Drapier, N, Sharland, M, Goossens, H, Drysdale, S

“…Documentation of the reasons for antibiotic prescribing was lowest in Latin America (52%). …”

Plasmid mediated metal and antibiotic resistance in marine pseudomonas / by 242559 Rajini Rani, D. B., Mahadevan, A

Combat against antibiotic resistance is a challenge in Bangladesh by Roney, Miah, Moyeenul Huq, A. K. M., Mohd Fadhlizil Fasihi, Mohd Aluwi

“…Antibiotic resistance is the result of bacteria changing and becoming resistant to an antibiotic's effects. …”
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Chemogenomics and orthology‐based design of antibiotic combination therapies by Chandrasekaran, Sriram, Cokol‐Cakmak, Melike, Sahin, Nil, Yilancioglu, Kaan, Kazan, Hilal, Collins, James J., Cokol, Murat

“…Combination antibiotic therapies are being increasingly used in the clinic to enhance potency and counter drug resistance. …”
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Understanding and Sensitizing Density-Dependent Persistence to Quinolone Antibiotics by Hamblin, Meagan, Gutierrez, Arnaud, Jain, Saloni R., Saluja, Prerna Bhargava, Lobritz, Michael Andrew, Collins, James J.

“…Physiologic and environmental factors can modulate antibiotic activity and thus pose a significant challenge to antibiotic treatment. …”
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Hydrogen Sulfide Sensitizes Acinetobacter baumannii to Killing by Antibiotics by Ng, Say Kong, Ong, Kai Xun, Surendran, Smitha Thamarath, Sinha, Ameya, Lai, Joey Jia Hui, Chen, Jacqueline, Liang, Jiaqi, Tay, Leona Kwan Sing, Cui, Liang, Loo, Hooi Linn, Ho, Peiying, Han, Jongyoon, Moreira, Wilfried

“…The production of endogenous hydrogen sulfide (H₂S) has been shown to confer antibiotic tolerance in all bacteria studied to date. …”
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Continuous bioactivity-dependent evolution of an antibiotic biosynthetic pathway by Johnston, Chad W, Badran, Ahmed H, Collins, James J

“…This selection drives antibiotic evolution and adapts BGCs for expression in different organisms, potentially providing clues to improve heterologous expression of antibiotics. …”
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Continuous bioactivity-dependent evolution of an antibiotic biosynthetic pathway by Johnston, Chad W., Badran, Ahmed H., Collins, James J.

“…This selection drives antibiotic evolution and adapts BGCs for expression in different organisms, potentially providing clues to improve heterologous expression of antibiotics. …”
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An engineered live biotherapeutic for the prevention of antibiotic-induced dysbiosis by Cubillos-Ruiz, Andrés, Alcantar, Miguel A, Donghia, Nina M, Cárdenas, Pablo, Avila-Pacheco, Julian, Collins, James J

“…Antibiotic-induced alterations in the gut microbiota are implicated in many metabolic and inflammatory diseases, increase the risk of secondary infections and contribute to the emergence of antimicrobial resistance. …”
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Combating biofilms and antibiotic resistance using synthetic biology by Lu, Timothy K. (Timothy Kuan-Ta), 1981-

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Polyelectrolyte multilayers for tunable release of antibiotics and other therapeutics by Chuang, Helen F

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Engineering Synthetic Bacteriophage to Combat Antibiotic-Resistant Bacteria by Lu, Timothy K., Collins, James J.

“…Antibiotic resistance is a rapidly evolving problem that is not being adequately met by new antimicrobial drugs. …”
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Microneedle delivery for improved efficacy of antiretroviral and antibiotic drugs by Stauber, Zachary Jason

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The eradication of bacterial persisters with antibiotic-generated hydroxyl radical by Haseley, Nathan Scott, Grant, Sarah Schmidt, Kaufmann, Benjamin B., Chand, Nikhilesh S., Hung, Deborah T.

“…We find that persisters are distinct from the larger antibiotic-susceptible population, as a small drop in dissolved oxygen (DO) saturation (20%) allows for their survival in the face of bactericidal antibiotics. …”
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Isolated cell behavior drives the evolution of antibiotic resistance by Artemova, Tatiana, Gerardin, Ylaine, Dudley, Carmel, Vega, Nic, Gore, Jeff

“…Bacterial antibiotic resistance is typically quantified by the minimum inhibitory concentration (MIC), which is defined as the minimal concentration of antibiotic that inhibits bacterial growth starting from a standard cell density. …”
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Hydrogen sulfide sensitizes Acinetobacter baumannii to killing by antibiotics by Ng, Say Yong, Ong, Kai Xun, Surendran, Smitha Thamarath, Sinha, Ameya, Lai, Joey Jia Hui, Chen, Jacqueline, Liang, Jiaqi, Tay, Leona Kwan Sing, Cui, Liang, Loo, Hooi Linn, Ho, Peiying, Han, Jongyoon, Moreira, Wilfried

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Chemical basis of combination therapy to combat antibiotic resistance by Si, Zhangyong, Pethe, Kevin, Chan-Park, Mary B.

“…This review discusses the chemical structures of effective β-lactamase inhibitors, outer membrane permeabilizers, and efflux pump inhibitors that act as adjuvant molecules of classical antibiotics. Rational design of the chemical structures of adjuvants will provide methods to impart or restore efficacy to classical antibiotics for inherently antibiotic-resistant bacteria. …”
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Engineered antibiotic nanoparticles for inhaled anti-biofilm therapy by Cheow, Wean Sin

“…A high initial antibiotic concentration ensures that maximum biofilm cells were killed, while the subsequent slower extended release maintained an antibiotic concentration high enough to arrest biofilm proliferation. …”
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Polymeric based nanoparticles carrier for improved antibiotic delivery. by Lin, Ivy Siew Leng.

“…The rapid mutation of microorganism causing antibiotic resistant and the difficulty of antibiotic delivery to poorly vascularised sites prevented and compromised the treatment of chronic infections using conventional systemic antibiotic therapy. …”
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Peptide-based antibacterial agents to overcome antibiotic resistance by Ahmad Hussen Tareq

“…Conventional antibiotics are becoming increasingly ineffective as a result of bacterial resistance, and multidrug-resistant bacteria are a severe threat to public health. …”
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