Engineering Synthetic Bacteriophage to Combat Antibiotic-Resistant Bacteria by Lu, Timothy K., Collins, James J.

“…Antibiotic resistance is a rapidly evolving problem that is not being adequately met by new antimicrobial drugs. …”
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Microneedle delivery for improved efficacy of antiretroviral and antibiotic drugs by Stauber, Zachary Jason

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The eradication of bacterial persisters with antibiotic-generated hydroxyl radical by Haseley, Nathan Scott, Grant, Sarah Schmidt, Kaufmann, Benjamin B., Chand, Nikhilesh S., Hung, Deborah T.

“…We find that persisters are distinct from the larger antibiotic-susceptible population, as a small drop in dissolved oxygen (DO) saturation (20%) allows for their survival in the face of bactericidal antibiotics. …”
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Isolated cell behavior drives the evolution of antibiotic resistance by Artemova, Tatiana, Gerardin, Ylaine, Dudley, Carmel, Vega, Nic, Gore, Jeff

“…Bacterial antibiotic resistance is typically quantified by the minimum inhibitory concentration (MIC), which is defined as the minimal concentration of antibiotic that inhibits bacterial growth starting from a standard cell density. …”
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Hydrogen sulfide sensitizes Acinetobacter baumannii to killing by antibiotics by Ng, Say Yong, Ong, Kai Xun, Surendran, Smitha Thamarath, Sinha, Ameya, Lai, Joey Jia Hui, Chen, Jacqueline, Liang, Jiaqi, Tay, Leona Kwan Sing, Cui, Liang, Loo, Hooi Linn, Ho, Peiying, Han, Jongyoon, Moreira, Wilfried

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Chemical basis of combination therapy to combat antibiotic resistance by Si, Zhangyong, Pethe, Kevin, Chan-Park, Mary B.

“…This review discusses the chemical structures of effective β-lactamase inhibitors, outer membrane permeabilizers, and efflux pump inhibitors that act as adjuvant molecules of classical antibiotics. Rational design of the chemical structures of adjuvants will provide methods to impart or restore efficacy to classical antibiotics for inherently antibiotic-resistant bacteria. …”
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Engineered antibiotic nanoparticles for inhaled anti-biofilm therapy by Cheow, Wean Sin

“…A high initial antibiotic concentration ensures that maximum biofilm cells were killed, while the subsequent slower extended release maintained an antibiotic concentration high enough to arrest biofilm proliferation. …”
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Polymeric based nanoparticles carrier for improved antibiotic delivery. by Lin, Ivy Siew Leng.

“…The rapid mutation of microorganism causing antibiotic resistant and the difficulty of antibiotic delivery to poorly vascularised sites prevented and compromised the treatment of chronic infections using conventional systemic antibiotic therapy. …”
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Peptide-based antibacterial agents to overcome antibiotic resistance by Ahmad Hussen Tareq

“…Conventional antibiotics are becoming increasingly ineffective as a result of bacterial resistance, and multidrug-resistant bacteria are a severe threat to public health. …”
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Synergy of novel cationic polymer with antibiotics in pseudomonas aeruginosa by Tiong, Wen Shuo

“…This study attempts to replicate and quantify the interaction between a novel polymer, 70-5, synthesized by SCBE (School of Chemical and Biochemical Engineering) and antibiotics of several different classes against Pseudomonas aeruginosa. …”
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Audit of antibiotic policies in the South East of England, 2004. by Mayon-White, R, Wiffen, P

“…OBJECTIVES: The antibiotic policies of hospitals and primary care trusts (PCTs) in South East England were audited in the summer of 2004, to see how they had improved since 2000. …”

Antibiotic consumption in low-income and middle-income countries by Hamers, R, van Doorn, H

Topical antibiotics with steroids for chronic suppurative otitis media by Brennan-Jones, CG, Chong, L-Y, Head, K, Burton, MJ, Schilder, AGM, Bhutta, MF

“…Antibiotics are commonly prescribed in combined preparations with steroids.…”

Antibiotic resistance: mitigation opportunities in livestock sector development by Robinson, T, Bu, D, Carrique-Mas, J, Fèvre, E, Gilbert, M, Grace, D, Hay, S, Jiwakanon, J, Kakkar, M, Kariuki, S, Laxminarayan, R, Lubroth, J, Magnusson, U, Thi Ngoc, P, Van Boeckel, T, Woolhouse, M

“…Intensive livestock farms have been far more dependent on antibiotics for growth promotion, disease prevention and disease treatment, so these structural changes bring about considerable increases in antibiotic use and this is predicted to double in the rapidly growing economies of Brazil, Russia, India, China and South Africa from 2010 to 2030 …”

Structural basis for antibiotic transport and inhibition in PepT2 by Parker, JL, Deme, JC, Lichtinger, SM, Kuteyi, G, Biggin, PC, Lea, SM, Newstead, S

“…The uptake and elimination of beta-lactam antibiotics in the human body are facilitated by the proton-coupled peptide transporters PepT1 (SLC15A1) and PepT2 (SLC15A2). …”

Changing the antibiotic prescribing behaviour of clinicians in primary care by Tonkin-Crine, S, Knox, K

The role of interspecies recombination in the evolution of antibiotic-resistant pneumococci by D'Aeth, JC, van der Linden, MP, McGee, L, de Lencastre, H, Turner, P, Song, J-H, Lo, SW, Gladstone, RA, Sá-Leão, R, Ko, KS, Hanage, WP, Breiman, RF, Beall, B, Bentley, SD, Croucher, NJ

“…Both occurred in the otherwise contrasting histories of the antibiotic-resistant S. pneumoniae lineages PMEN3 and PMEN9. …”

Lower respiratory tract infection is no argument for prescribing antibiotics by Hopstaken, R, Butler, C, Muris, J, Knottnerus, A, Kester, A, Rinkens, P, Dinant, G

The evolution of antibiotic resistance in a structured host population by Blanquart, F, Lehtinen, S, Lipsitch, M, Fraser, C

“…Explicitly modelling the antibiotic treatment reveals that the emergence of a resistant strain is favoured by more frequent but shorter antibiotic courses, and by higher transmission rates. …”

Fine with five? Shorter antibiotic courses for childhood meningitis. by Snape, MD, Kelly, D