Molecular analysis of the acinetobacter baumannii biofilm-associated protein by Sidjabat, Hanna E., Paterson, David L., Nimmo, Graeme R., Lipman, Jeffrey, Schembri, Mark A., Goh, Hwee Mian Sharon, Beatson, Scott A., Totsika, Makrina, Moriel, Danilo G., Phan, Minh-Duy, Szubert, Jan, Runnegar, Naomi

“…The ability of A. baumannii to survive in the hospital environment for long periods is linked to antibiotic resistance and its capacity to form biofilms. …”
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Effect of the additional cysteine 503 of vancomycin-resistant Enterococcus faecalis (V583) alkylhydroperoxide reductase subunit F (AhpF) and the mechanism of AhpF and subunit C ass... by Toh, Yew Kwang, Shin, Joon, Balakrishna, Asha Manikkoth, Kamariah, Neelagandan, Grüber, Ardina, Eisenhaber, Frank, Eisenhaber, Birgit, Grüber, Gerhard

“…Therefore, knowledge about this defense system is essential to understand its antibiotic-resistance and survival in hosts. Recently, we described the crystallographic structures of EfAhpC, the two-fold thioredoxin-like domain of EfAhpF, the novel phenomenon of swapping of the catalytic domains of EfAhpF as well as the unique linker length, connecting the catalytically active N-and C-terminal domains of EfAhpF. …”
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High-density three-dimensional network of covalently linked nitric oxide donors to achieve antibacterial and antibiofilm surfaces by Wang, Liping, Hou, Zheng, Pranantyo, Dicky, Kang, En-Tang, Chan-Park, Mary B.

“…Bacterial colonization on biomedical devices often leads to biofilms that are recalcitrant to antibiotic treatment and the leading cause of hospital-acquired infections. …”
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Enhanced BiFeO₃/Bi₂Fe4O₉/H₂O₂ heterogeneous system for sulfamethoxazole decontamination : system optimization and degradation pathways by Hu, Zhong-Ting, Liu, Jia-Wei, Zhao, Jia, Ding, Yin, Jin, Ziyan, Chen, Jinghuan, Dai, Qizhou, Pan, Bingjun, Chen, Zhong, Chen, Jianmeng

“…Sulfonamides as the major antibiotic have become emerging contaminants worldwide in aquatic environments. …”
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Polyimidazolium protects against an invasive clinical isolate of Salmonella Typhimurium by Mon, Khin K. Z., Si, Zhangyong, Chan-Park, Mary B., Kenney, Linda J.

“…Collectively, our results highlight the potential for PIM1 as a replacement therapy for existing antibiotic applications on the poultry farm, given the efficiency and low toxicity profile demonstrated in our agriculturally relevant chicken embryo model.…”
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Nanoparticles of short cationic peptidopolysaccharide self-assembled by hydrogen bonding with antibacterial effect against multidrug-resistant bacteria by Hou, Zheng, Shankar, Yogesh Vikhe, Liu, Yang, Ding, Feiqing, Subramanion, Jothy Lachumy, Ravikumar, Vikashini, Zamudio-Vázquez, Rubí, Keogh, Damien, Lim, Huiwen, Tay, Moon Yue Feng, Bhattacharjya, Surajit, Rice, Scott A., Shi, Jian, Duan, Hongwei, Liu, Xue-Wei, Mu, Yuguang, Tan, Nguan Soon, Tam, Kam C., Pethe, Kevin, Chan-Park, Mary B.

“…In vivo study (using a murine excisional wound model) shows that CSM5-K5 suppresses the growth of methicillin-resistant Staphylococcus aureus (MRSA) bacteria by 4.0 orders of magnitude, an efficacy comparable to that of the last resort MRSA antibiotic vancomycin; it is also non-inflammatory with little/no activation of neutrophils (CD11b and Ly6G immune cells). …”
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Phenotypic antimicrobial susceptibility of E. coli from raw meat, ready-to-eat meat and its related samples in one health context by Adzitey, Frederick, Nurul Huda, Amir Husni Mohd Shariff

“…The E. coli isolates showed twenty-two different resistant patterns, with a multiple antibiotic resistance index of 0.0 to 0.7. The resistant pattern amoxicillin (A, n = 6 isolates) and amoxicillin-trimethoprim (A-TM, n = 6 isolates) were the most common. …”
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Phenotypic antimicrobial susceptibility of Escherichia coli from raw meats, ready-to-eat meats, and their related samples in one health context by Frederick Adzitey, Nurul Huda, Amir Husni Mohd Shariff

“…The E. coli isolates showed twenty-two different resistant patterns, with a multiple antibiotic resistance index of 0.0 to 0.7. The resistant pattern amoxicillin (A, n = 6 isolates) and amoxicillin-trimethoprim (A-TM, n = 6 isolates) were the most common. …”
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Synthesis of Silver Nanoparticles from Extracts of Wild Ginger (Zingiber zerumbet) with Antibacterial Activity against Selective Multidrug Resistant Oral Bacteria by Muhammad Ramzan, Mohmed Isaqali Karobari, Artak Heboyan, Roshan Noor Mohamed, Mohammed Mustafa, Syed Nahid Basheer, Vijay Desai, Salma Batool, Naveed Ahmed, Basit Zeshan

“…Antibiotic resistance rate is rising worldwide. Silver nanoparticles (AgNPs) are potent for fighting antimicrobial resistance (AMR), independently or synergistically. …”
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Designing a novel Aerolysin-based multiepitope vaccine against Aeromonas hydrophila isolated from Osphronemus goramy using reverse vaccinology: an in silico approach by Rozi, ., Tyasningsih, Wiwiek, Rahmahani, Jola, Aksono, Eduardus Bimo, Yunus, Muchammad, Al Arif, Mohammad Anam, Kuncorojati, Suryo, Kusdarwati, Rahayu, Sari, Putri Desi Wulan, Azmai, Mohammad Noor Amal, Salleh, Annas, Khanand, Nadeem, Suwarno, .

“…Targeting the specific toxin aerolysin in A. hydrophila is crucial to address antibiotic resistance and the lack of adequate and protective vaccines against this intracellular and extracellular pathogen. …”
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Acute gastroenteritis among indigenous paediatric patients – a descriptive study in a rural district Hospital, Sarawak by Cheah, Whye Lian, Lee, Ping Yein, Syed Abdul Rahman, Syed Alwi, Kana, Kamarudin, Albela, Henrietta, Lau, Ee Hua, O., Noraini, Wan Azman, Siti Sanaa

“…The most common treatment used is oral rehydration solutions (85.4%), followed by intravenous bolus or drip (82.3%), paracetamol (79%) and antibiotic (36.2%). Peak incidence of admissions was between November to January. …”
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Potent Anticancer, Antioxidant and Antibacterial Activities of Isolated Flavonoids from Asplenium by Jarial, Rini, Thakur, Sveta, Mimi Sakinah, A. M., Zularisam, A. W., Sharad, Amit, Kanwar, S. S., Singh, Lakhveer

“…Gliricidin-7-O-hexoside and quercetin-7-O-rutinoside’s inhibitory activities were comparable to standard antibiotic, amoxicillin (p > 0.05). Herein we report for the first time a number of flavonoids that may act as the source of therapeutically useful compounds against MDR pathogens. …”
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Potent anticancer, antioxidant and antibacterial activities of isolated flavonoids from Asplenium nidus by Rini, Jarial, Thakur, Sveta, Mimi Sakinah, A. M., Zularisam, A. W., Sharad, Amit, Kanwar, S. S., Singh, Lakhveer

“…Gliricidin-7-O-hexoside and quercetin-7-O-rutinoside’s inhibitory activities were comparable to standard antibiotic, amoxicillin (p > 0.05). Herein we report for the first time a number of flavonoids that may act as the source of therapeutically useful compounds against MDR pathogens. …”
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Convergent synthesis of new N -substituted 2-{[5-(1H -indol-3-ylmethyl)-1,3,4-oxadiazol-2-yl]sulfanyl} acetamides as suitable therapeutic agents by Rubab, Kaniz, Abbasi, Muhammad Athar, Ur-Rehman, Aziz, Siddiqui, Sabahat Zahra, Ashraf, Muhammad, Shaukat, Ayesha, Ahmad, Irshad, Lodhi, Muhammad A., Khan, Farman Ali, Shahid, Muhammad, Akhtar, Muhammad Nadeem

“…Similarly, compounds 8b and 8c showed very good antibacterial activity against Salmonella typhi, which was very close to that of ciprofloxacin, a standard antibiotic used in this study. 8c and 8l also showed very good antibacterial activity against Staphylococcus aureus as well. …”
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Tunable staged release of therapeutics from layer-by-layer coatings with clay interlayer barrier by Min, Jouha, Braatz, Richard D., Hammond, Paula T.

“…Herein, we demonstrate the ability to develop a self-assembled, polymer-based conformal coating, built by using a water-based layer-by-layer (LbL) approach, as a dual-purpose biomimetic implant surface that provides staggered and/or sustained release of an antibiotic followed by active growth factor for orthopedic implant applications. …”
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Self-assembly of human defensin 6 and its role in innate immunity and siderophore-based strategies to target Gram-Negative bacteria by Chairatana, Phoom

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Kinetically E-selective macrocyclic ring-closing metathesis by Shen, Xiao, Nguyen, Thach T., Koh, Ming Joo, Xu, Dongmin, Speed, Alexander W. H., Hoveyda, Amir H., Schrock, Richard Royce

“…We highlight the utility of the approach by preparing recifeiolide (a 12-membered-ring antibiotic) and pacritinib (an 18-membered-ring enzyme inhibitor), the Z-isomer of which is less potent than the E-isomer. …”
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Virtual microfluidics : a novel single-cell technology based on diffusion-restricted reaction that makes high-quality low-input genomic research accessible by Xu, Liyi, Ph. D. Massachusetts Institute of Technology

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Endoribonuclease toxin-antitoxin systems in bacteria : targets and growth inhibition by Culviner, Peter Holmes.

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Investigation of two-component signaling systems in Pseudomonas aeruginosa and their roles in the mucus barrier by Wang, Benjamin X.

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