Profiling microbial communities in idiopathic granulomatous mastitis by Ong, Seeu Si, Xu, Jia, Sim, Choon Kiat, Khng, Alexis Jiaying, Ho, Peh Joo, Kwan, Philip Kam Weng, Ravikrishnan, Aarthi, Tan, Benita Kiat-Tee, Tan, Qing Ting, Tan, Ern Yu, Tan, Su-Ming, Putti, Thomas Choudary, Lim, Swee Ho, Tang, Serene Ee Ling, Nagarajan, Niranjan, Karnani, Neerja, Li, Jingmei, Hartman, Mikael

“…Three other species and nineteen genera were statistically significant in paired IGM pus−skin comparison after antibiotic treatment adjustment and multiple comparisons correction. …”
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Electrospun polyvinyl alcohol fibres incorporating an antimicrobial gel for enzymatically controlled reactive oxygen species release by Mieles, Joel Yupanqui, Vyas, Cian, Daskalakis, Evangelos, Hassan, Mohamed, Birkett, James, Omar, Abdalla M., Humphreys, Gavin, Diver, Carl, Bartolo, Paulo

“…Wounds pose a risk to the skin, our body’s primary defence against infections. The rise of antibiotic resistance has prompted the development of novel therapies. …”
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In vitro evaluatinon of oral hygiene commercial products for antimicrobial susceptibility and in combination with the extracts from four spices by Muna, Jalal Ali

“…We found a higher bacterial population was in the age group of 3–40 years than other two groups, with approximately 44%. Antibiotic susceptibility test against the isolates showed that chloramphenicol had the highest susceptibility effect with 83.2%. …”
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Two-dimensional exploration of two-dimensional carbon : imaging and sensing applications by Bardhan, Neelkanth Manoj

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The endoribonuclease YbeY is linked to proper cellular morphology and virulence in 2 Brucella abortus by Budnick, James A., Sheehan, Lauren M., Colquhoun, Jennifer M., Dunman, Paul M., Roop, Martin, Jr., Walker, Graham C.

“…Importance Brucella spp. are highly efficient bacterial pathogens of animals and humans, causing significant morbidity and economic loss worldwide, and relapse of disease often occurs following antibiotic treatment of human brucellosis. As such, novel therapeutic strategies to combat Brucella infections are needed. …”
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Structural insights into conformationally-gated reactions catalyzed by thiamine pyrophosphate-dependent enzymes by Chen, Yang-Ting(Percival Yang Ting)

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Congruent microbiome signatures in fibrosis-prone autoimmune diseases: IgG4-related disease and systemic sclerosis by Plichta, Damian R., Somani, Juhi, Pichaud, Matthieu, Wallace, Zachary S., Fernandes, Ana D., Perugino, Cory A., Lähdesmäki, Harri, Stone, John H., Vlamakis, Hera, Chung, Daniel C., Khanna, Dinesh, Pillai, Shiv, Xavier, Ramnik J.

“…Methods The gut microbiomes from IgG4-RD and SSc patients as well as healthy individuals with no recent antibiotic treatment were studied by metagenomic sequencing of stool DNA. …”
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Engineering Escherichia coli to assimilate β-alanine as a major carbon source by Poon, Nga Y., Sinskey, Anthony J., Zhou, Kang

“…First, PaBapt and both VnMmsDs were expressed from a single plasmid to mitigate antibiotic stress. Second, a native 3-hydroxy acid dehydrogenase (EcYdfG) was disrupted to address the carbon loss to 3-hydroxypropionate (3-HP) production from MSA. …”
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Introducing the starlet sea anemone Nematostella vectensis as a model for investigating microbial mediation of health and disease in hexacorals by Har, Jia Yi

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Exploiting receptor flexibility to improve the accuracy of structure-based virtual screening by Yaw, Awuni

“…In addition, it was sought to understand the dynamics of the nucleotide-A22 binding site of the bacterial actin MreB. A22 is an antibiotic-like small molecule that perturbs the rod cell shape of bacteria and has been suggested to inhibit MreB by targeting ATP hydrolysis. …”
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Investigating membrane morphological responses induced by antimicrobial lipids and correlations with biological activity by Yoon, Bo Kyeong

“…Antimicrobial lipids such as fatty acids and monoglycerides are promising antibacterial agents that destabilize bacterial cell membranes, representing a new treatment approach that might overcome the challenges of antibiotic-resistant bacteria. To date, most studies on antimicrobial lipids have focused on evaluating inhibitory activity against target bacterium by indirect biological methods. …”
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PELAKSANAAN SURGICAL PATIENT SAFETY TERHADAP ADVERSE EVENTS PASCAOPERASI BEDAH DIGESTIF DI INSTALASI BEDAH RSUP DR. SARDJITO YOGYAKARTA by , Erikson Siagian, , Prof. dr. Iwan D., M.Med.Sc., Ph.D.

“…Stages Time Out: Operators who do re-confirm the identity of the patient before surgery by 68.2%, giving prophylactic antibiotic injection is less than 60 minutes before skin incision of 77.3%. …”

Genomic adaptation in antimicrobial resistance: elucidating the route and effects in Acinetobacter baumannii / Mohamad Izwan Ismail by Ismail, Mohamad Izwan

“…From the results it is deduced that the chronology of intrinsic mutations is dependent on the types and intensity of selective pressures enacted, even on the same bacteria. Antibiotic pressure under in vitro and in vivo conditions has also resulted in development of different mutations leading to similar resistance profiles. …”
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D-mannose for prevention of recurrent urinary tract infection among women: a randomized clinical trial by Hayward, G, Mort, S, Hay, AD, Moore, M, Thomas, NPB, Cook, J, Robinson, J, Williams, N, Maeder, N, Edeson, R, Franssen, M, Grabey, J, Glogowska, M, Yang, Y, Allen, J, Butler, C

“…Secondary outcomes included symptom duration, antibiotic use, time to next medically attended UTI, number of suspected UTIs, and UTI-related hospital admissions.…”

Small molecule tools for structural and functional studies of 2OG oxygenases by Lesniak, R

“…RL368, in particular, showed superior inhibition to the known inhibitors L- and D-captopril, and, pleasingly displays cell-based potential as an antibiotic following antimicrobial susceptibility assays against Gram negative pathogens of clinical origin; <em>E. coli, E. aerogenes</em> and <em>K. pneumoniae</em>.…”

Impact of amoxicillin therapy on resistance selection in patients with community-acquired lower respiratory tract infections: a randomized, placebo-controlled study. by Malhotra-Kumar, S, Van Heirstraeten, L, Coenen, S, Lammens, C, Adriaenssens, N, Kowalczyk, A, Godycki-Cwirko, M, Bielicka, Z, Hupkova, H, Lannering, C, Mölstad, S, Fernandez-Vandellos, P, Torres, A, Parizel, M, Ieven, M, Butler, C, Verheij, T, Little, P, Goossens, H

“…This evidence further supports European guidelines that recommend amoxicillin when an antibiotic is indicated for community-acquired lower respiratory tract infections.…”

Intensified treatment with high dose rifampicin and levofloxacin compared to standard treatment for adult patients with tuberculous meningitis (TBM-IT): protocol for a randomized c... by Heemskerk, D, Day, J, Chau, T, Dung, N, Yen, N, Bang, N, Merson, L, Olliaro, P, Pouplin, T, Caws, M, Wolbers, M, Farrar, J

“…Despite the introduction of antibiotic treatment for tuberculosis the mortality rate for tuberculous meningitis remains high; approximately 25% for HIV-negative and 67% for HIV positive patients with most deaths occurring within one month of starting therapy. …”

Generation of stem cell models of ITPR1-related neurological disorders using a novel genome engineering approach by Parolin Schnekenberg, R

“…</p> <p>This thesis describes the development of a CRISPR/Cas9 system designed to introduce ITPR1 mutations into human stem cells using positive-negative antibiotic selection. The aim was to develop a system that could not only generate stem cell models of different ITPR1 mutations but also be easily adapted for any other genes or mutations of interest.…”

The basis of genetic rearrangements in mupirocin resistance plasmids by Needham, C, Needham, Christine

“…Mupirocin is a novel topical antibiotic active against many Gram positive species, including staphylococci and effective in the treatment and prevention of staphylococcal infections. …”

Infection Manager System (IMS) as a new hemocytometry-based bacteremia detection tool: A diagnostic accuracy study in a malaria-endemic area of Burkina Faso by Post, A, Kaboré, B, Bognini, J, Diallo, S, Lompo, P, Kam, B, Herssens, N, van Opzeeland, F, van der Gaast-de Jongh, CE, Langereis, JD, de Jonge, MI, Rahamat-Langendoen, J, Bousema, T, Wertheim, H, Sauerwein, RW, Tinto, H, Jacobs, J, de Mast, Q, van der Ven, AJ

“…Its high NPV for bacteremia has the potential to improve antibiotic dispensing practices in healthcare facilities with hematology analyzers. …”