Characterization of genetic elements carrying mcr-1 gene in Escherichia coli from the community and hospital settings in Vietnam by Vu Thi Ngoc, B, Le Viet, T, Nguyen Thi Tuyet, M, Nguyen Thi Hong, T, Nguyen Thi Ngoc, D, Le Van, D, Chu Thi, L, Tran Huy, H, Penders, J, Wertheim, H, van Doorn, HR

“…Colocalization of mcr-1 and other antibiotic resistance genes (ARGs) on multireplicon plasmids adds another layer of complexity to the rapid dissemination of mcr-1 genes among community and hospital bacterial populations and to the slow pandemic of antimicrobial resistance (AMR) in general.…”

A crystallographic comparison of protein molecules with related conformations by Nixon, P, Nixon, P.E.

“…An application of these methods to the antibiotic thiostrepton, using an almost complete structure from another crystal form as a model was successful.…”

Free radical methodology and approaches to the synthesis of roseophilin by Burrows, J, Jeremy N. Burrows

“…</p> <p>A review of the antibiotic Roseophilin is presented. Cycloaddition-fragmentation approaches to medium and large rings are reviewed as a prelude to our first route, the proposed Michael addition-retro-aldol fragmentation of the Diels-Alder adduct derived from isopropyl-cyclopentadiene and cyclodec- 2-yn-1-one. …”

Quantitative study of Clostridium difficile transmission using extensive epidemiological data and whole genome sequencing by Eyre, DW

“…<p><em>Clostridium difficile</em> is a leading healthcare-associated infection, which causes diarrhoea, and is almost exclusively precipitated by antibiotic exposure. Traditionally <em>C. difficile</em> infection (CDI) has been considered predominantly transmitted within hospitals. …”

Epidemiology of extended-spectrum beta-lactamase and carbapenemase-producing enterobacterales in the Greater Mekong Subregion: A systematic-review and meta-analysis of risk factors... by Singh, SR, Teo, AKJ, Prem, K, Ong, RT-H, Ashley, EA, van Doorn, HR, Limmathurotsakul, D, Turner, P, Hsu, LY

“…Twelve studies were included in the meta-analysis of risk factors associated with isolation of ESBL. Recent antibiotic exposure was the most studied variable and showed a significant positive association with ESBL-E isolation (pooled OR: 2.9, 95%CI: 2.3–3.8) followed by chronic kidney disease (pooled OR: 4.7, 95%CI: 1.8–11.9), and other co-morbidities (pooled OR: 1.6, 95%CI: 1.2–2.9). …”

Development and pre-clinical evaluation of HIV-1 vaccines by Mbewe-Mvula, A

“…</p> <p>In the second study, I aimed to construct marker-less mycobacterium-vectored HIV-1 vaccines using the operator-repressor titration (ORT®) system as an alternative system for antibiotic resistance gene free vaccines. This rBCG vaccine would express the HIVconsv immunogen. …”

Excess resource use and cost of drug-resistant infections for six key pathogens in Europe: a systematic review and Bayesian meta-analysis by Kingston, R, Vella, V, Pouwels, KB, Schmidt, JE, El-Abasiri, RAA, Reyna-Villasmil, E, Hassoun-Kheir, N, Harbarth, S, Rodríguez-Baño, J, Tacconelli, E, Arieti, F, Gladstone, BP, de Kraker, MEA, Naylor, NR, Robotham, JV

“…</p> <p><i>Study eligibility criteria:</i> Resource use and cost outcomes (including excess length of stay, overall costs, and other excess in or outpatient costs) were compared between patients with defined antibiotic-resistant infections caused by carbapenem-resistant (CR) <i>Pseudomonas aeruginosa</i> and <i>Acinetobacter baumannii</i>, CR or third-generation cephalosporin <i>Escherichia coli</i> (3GCREC) and <i>Klebsiella pneumoniae</i>, methicillin-resistant <i>Staphylococcus aureus</i>, and vancomycin-resistant <i>Enterococcus faecium</i>, and patients with drug-susceptible or no infection.…”

Visualizing variation within Global Pneumococcal Sequence Clusters (GPSCs) and country population snapshots to contextualize pneumococcal isolates by Gladstone, RA, Lo, SW, Goater, R, Yeats, C, Taylor, B, Hadfield, J, Lees, JA, Croucher, NJ, van Tonder, AJ, Bentley, LJ, Quah, FX, Blaschke, AJ, Pershing, NL, Byington, CL, Balaji, V, Hryniewicz, W, Sigauque, B, Ravikumar, KL, Almeida, SCG, Ochoa, TJ, Ho, PL, du Plessis, M, Ndlangisa, KM, Cornick, JE, Kwambana-Adams, B, Benisty, R, Nzenze, SA, Madhi, SA, Hawkins, PA, Pollard, AJ, Everett, DB, Antonio, M, Dagan, R, Klugman, KP, von Gottberg, A, Metcalf, BJ, Li, Y, Beall, BW, McGee, L, Breiman, RF, Aanensen, DM, Bentley, SD, The Global Pneumococcal Sequencing Consortium

“…Knowledge of pneumococcal lineages, their geographic distribution and antibiotic resistance patterns, can give insights into global pneumococcal disease. …”

Carbapenem resistance gene crisis in A. baumannii: A computational analysis by Nureen Zahra, Basit Zeshan, Musarat Ishaq

“…In silico analysis of antibiotic resistance genes against carbapenem are the blaOXA-51, blaOXA-23, blaOXA-58, blaOXA-24, blaOXA-143, NMD-1 and IMP-1 in A. baumannii. …”
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Detection of community-acquired methicillin-resistant staphylococcus aureus (CA-MRSA) transmission in the local community using molecular typing techniques by Lia Natasha Amit

“…Thirty-seven MRSA abscess isolates of index patients which were identified from the cefoxitin antibiotic susceptibility tests were collected from Pathology Laboratory. …”
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Optimisation of gusA gene transfer into cocoa (Theobroma cacao) via agrobacterium tumefaciens-mediated transformation by Anisah Savantil

“…The binary vector contains a CaMV 35S-driven β-glucuronidase (GUS) gene and a complete neomycin phosphotransferase II (nptII) gene for conferring plant resistance to the antibiotic paromomycin. Callus induction medium (IM) for clone PBC 123 consisted of Driver and Kuniyuki Walnut (DKW) minerals, glucose, vitamins, 2 mg l-1 2, 4-dichlorophenoxyacetic acid (2,4-D) and 0.005 mg l-1 Thidiazuron (TDZ) pH5.3. …”
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Synthesis of nickel cobalt-codoped tin oxide nanoparticles from Psidium guajava with anticancer properties by Elderdery, Abozer Y., Alzahrani, Badr, Alabdulsalam, Abdulrahim A., Alanazi, Fehaid, Hamza, Siddiqa M. A., Elkhalifa, Ahmed M. E., Alhamidi, Abdulaziz H., Mohamedain, A., Subbiah, Suresh Kumar, Mok, Pooi Ling

“…Induces mitochondrial oxidative stress with nickel–cobalt-codoped tin oxide nanoparticles from Psidium guajava, which is a potential drug candidate for the antibiotic, antifungal, and anticancer activities of plant-based nanoparticles.…”

Best practices for managing malodorous and infected wounds in advanced cervical cancer by Hamid, Habibah Abdul, Lin, Xiaoqian, Qin, Yuan Kun, Akim, Abdah Md, Zhang, Longjiu, Wang, Jue, Wang, Hui, Li, Ying, Teng, Xiaofei, Zhang, Shangmeng, Xu, Huanyu, Lin, Xiaoqing

“…Additional approaches, such as photodynamic therapy and topical antibiotic therapy, demonstrated significant effectiveness, as evidenced by odour reductions of 70 and 75, respectively, and patient satisfaction ratings of 4.3 and 4.2. …”
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Genomic analysis and biological characterization of a novel Schitoviridae phage infecting Vibrio alginolyticus by Tajuddin, Sofiah, Khan, Asif M., Li, Chuin Chong, Wong, Chuan Loo, Jia, Sen Tan, Ina-Salwany, Md Yasin, Lau, Han Yih, Kok, Lian Ho, Mariatulqabtiah, Abdul Razak, Wen, Siang Tan

“…The genome contains an extremely large virion-associated RNA polymerase gene and two smaller non-virion-associated RNA polymerase genes, which are hallmarks of schitoviruses. No antibiotic genes were found in the ΦImVa-1 genome. This is the first paper describing the biological properties, morphology, and the complete genome of a V. alginolyticus-infecting schitovirus. …”

High Internal Phase Emulsion As A Reaction Medium For Fabrication Of Brushite Crystal by Lim, Hong Ngee

“…Sodium ampicillin, a wide spectrum antibiotic, was successfully loaded into the pores of the crystals and subsequently released in vitro for 14 days. …”
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Antimicrobial susceptibility patterns and molecular characteristics of group B Streptococcus isolated from three major hospitals in Malaysia by Suhaimi, Mohd. Emir Shafiq

“…The Centers for Disease Control and Prevention (CDC) published guidelines for intrapartum antibiotic prophylaxis since 1996 and recommended penicillin or ampicillin as the drugs of choice for prevention of GBS disease. …”
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Efficacy of Various Local Honey For The Treatment Of Burn Wounds by Mohd Zohdi, Rozaini

“…Recently, honey has been revived as an effective treatment for wounds and the interests that spark in approachng alternative treatments stem partly from the emergence of antibiotic-resistance pathogens. In addition burn care duration of hospita is an expensive proposition which requires significant 1 stay as well as expensive medications. …”
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Effects of Lactobacillus Strains as a Probiotic and a Hypolipidaemic Agent for Chickens by Ramasamy, Kalavathy

“…The feeding trials showed that the supplementation of a mixture of the 1 2 Lactobacillus cultures (LC), as a probiotic for broilers, significantly improved growth equivalent to that provided by the antibiotic, oxytetracycline, but the feed conversion ratio was better in LC-fed broilers. …”
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Evaluation of different strains of Spirulina on selected culture media as potential feed supplement for broiler by Abdul Ghofar, Hasfar Syafiqah

“…However, due to public concern on the antibiotic residues in the meat, the feed business tends to use natural ingredients as supplement. …”
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Molecular Characterisation of Vibrio Vulnificus Isolated from Cockles (Anadara Granos A) and Shrimps (Panaeus Indicus) in Malaysia by Tengku Ahmad, Tengku Ahbrizal Farizal

“…An strains from shrimps were resistant to penicillin (100%),gentamicin. Twenty-six and 18 antibiotic resistance patterns were observed from cockles and shrimps, respectively. …”
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