Solubility measurement and modeling of hydroxychloroquine sulfate (antimalarial medication) in supercritical carbon dioxide by Gholamhossein Sodeifian, Chandrasekhar Garlapati, Maryam Arbab Nooshabadi, Fariba Razmimanesh, Amirmuhammad Tabibzadeh

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Ethics in research by Maria Isabel Toulson Davisson Correia

“…Ethics in research and how it is translated into practice is fundamental to rule out any potential misconduct either with the scientific method or the way results are presented to the world, thus impacting patients outcomes.The last two years of the Covid-19 pandemic were prolific in exposing the scientific community and healthcare professionals to the many flaws regarding the different studies either with promising simple treatments or sophisticated medications.Supposedly high-profile papers with the antimalarial medication hydroxychloroquine either favoring its use or indicating the risk of death were retracted from very prestigious journals such as the Lancet and the New England Journal of Medicine.Ethics in research became fundamental in reaction to abuses practiced against people as the Nazi studies on concentration camp prisoners or the syphilis study with American prisoners or the US governments radiation experiment.…”
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Patients opinion and adherence to antimalarials in lupus erythematosus and rheumatoid arthritis treatment by Renata Tavares de Souza Cabral, Evandro Mendes Klumb, Sueli Carneiro

“…Methods: A cross-sectional study of patients treated with antimalarial medication for a period equal to or longer than 1 year attended between November 2012 and October 2014. …”
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Multidisciplinary Collaboration between a Community Pharmacy and a Travel Clinic in a Swiss University Primary Care and Public Health Centre by Jérôme Berger, Marie-José Barbalat, Vanessa Pavón Clément, Blaise Genton, Olivier Bugnon

“…Pharmacists and pharmacy technicians participate in this collaboration to provide (1). counselling and clinical activities with travellers (e.g., pre-travel consultations and advice to travellers), (2). clinical pharmacy expertise and medicine information services (e.g., selection of an appropriate antimalarial medication for a traveller to manage of drug-drug interactions), (3). technical and logistical activities related to medicines and vaccines (e.g., management of vaccine shortages and specially imported medicines and vaccines from foreign countries) and (4). educational activities (e.g., undergraduate pharmacy teaching and continuous education to community pharmacists). …”
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Synergistic antimalarial treatment of Plasmodium berghei infection in mice with dihydroartemisinin and Gymnema inodorum leaf extract by Sakaewan Ounjaijean, Voravuth Somsak

“…Artemisinin-based combination therapies (ACTs) are currently the most effective antimalarial medication. Malaria parasites are growing more resistant to ACTs, particularly in Southeast Asia. …”
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The current use of the artemisinin-based Combination Therapies in adult patients at a Tertiary Hospital, South-South Nigeria by STEPHEN AYINBUOMWAN, Abimbola Opadeyi, Ambose Isah

“…Their preferred antimalarial medication, previous use of antimalarial monotherapies, current ACT use; cost considerations, and adverse effects profile were sought. …”
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The current use of the artemisinin-based Combination Therapies in adult patients at a Tertiary Hospital, South-South Nigeria by STEPHEN AYINBUOMWAN, Abimbola Opadeyi, Ambose Isah

“…Their preferred antimalarial medication, previous use of antimalarial monotherapies, current ACT use; cost considerations, and adverse effects profile were sought. …”
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Hydroxychloroquine induced QT prolongation in a schizoaffective patient being treated for a COVID-19 infection: A Case Report by R. Amazan, P. Korenis, S. Gunturu

“… Introduction Hydroxychloroquine an antimalarial medication has been approved in March 2020 by FDA for treatment of hospitalized patient with COVID-19 infection. …”
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High-Dose Primaquine Induces Proximal Tubular Degeneration and Ventricular Cardiomyopathy Linked to Host Cells Mitochondrial Dysregulation by Atthasit Rabiablok, Borimas Hanboonkunupakarn, Khwanchanok Tuentam, Kamonpan Fongsodsri, Tapanee Kanjanapruthipong, Sumate Ampawong

“…Primaquine (PQ) is the only antimalarial medication used to eradicate many species of <i>Plasmodium</i> gametocytes and prevent relapse in vivax and ovale malarias. …”
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EVALUASI RESPON PENGOBATAN MALARIA DI RSUD SUMBAWA by , Tri Widiastuti, , Prof. Dr. Mustofa, M.Kes., Apt.

“…To determine the treatment response of malaria patients, to assess the suitability of the Depkes Malaria Standard Treatment with treatment carried out in RSUD Sumbawa, and find out what factors are influencing the success / failure of antimalarial medication therapy. Observational study conducted by descriptive evaluative study design through data prospectively tracking of medical records and follow up the development of malaria patients to day 28. …”

EVALUASI RESPON PENGOBATAN MALARIA DI RSUD SUMBAWA by , Tri Widiastuti, , Prof. Dr. Mustofa, M.Kes., Apt.

“…To determine the treatment response of malaria patients, to assess the suitability of the Depkes Malaria Standard Treatment with treatment carried out in RSUD Sumbawa, and find out what factors are influencing the success / failure of antimalarial medication therapy. Observational study conducted by descriptive evaluative study design through data prospectively tracking of medical records and follow up the development of malaria patients to day 28. …”

Symptomatic illness and treatment of Plasmodium falciparum malaria in African children by Dalrymple, U

“…</p> <p> The second research focus was to develop an essential adjustment to household survey data to assess the duration a <em>P. falciparum</em>-infected individual remains positive via rapid diagnostic test after being treated with antimalarial medication. This adjustment was used in subsequent chapters, allowing for more accurate assessment of the likelihood of a febrile individual in the household survey datasets having experienced a MAF or NMFI in the two weeks preceding the survey.…”

Solution Structures and Dynamic Assembly of the 24-Meric Plasmodial Pdx1–Pdx2 Complex by Najeeb Ullah, Hina Andaleeb, Celestin Nzanzu Mudogo, Sven Falke, Christian Betzel, Carsten Wrenger

“…They have developed effective resistance mechanisms against most antimalarial medication, causing an urgent need to identify new antimalarial drug targets. …”
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A consultation on the optimization of controlled human malaria infection by mosquito bite for evaluation of candidate malaria vaccines. by Laurens, M, Duncan, C, Epstein, J, Hill, A, Komisar, J, Lyke, K, Ockenhouse, C, Richie, T, Roestenberg, M, Sauerwein, R, Spring, MD, Talley, A, Moorthy, V

“…Early clinical investigations of candidate malaria vaccines and antimalarial medications increasingly employ an established model of controlled human malaria infection (CHMI). …”

Prophylaxis Failure and Successful Management of Delayed-Onset Malaria with Renal Complications: A Case Report with Oral Artemether-Lumefantrine Treatment by Ilir Tolaj, Gramoz Bunjaku, Murat Mehmeti, Yllka Begolli

“…Due to limited access to parenteral antimalarial medications in Kosovo, the patient received oral artemether-lumefantrine, resulting in clinical improvement. …”
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Recent approaches in the drug research and development of novel antimalarial drugs with new targets by Chinnappanna Naveen Kumar Reddy, Yennam Gopi, Chaitanya Chaitanya Budagam Haima Naga Venkata, Pottathil Shinu, Borah Pobitra, Venugopala Katharigatta N., Deb Pran Kishore, Mailavaram Raghu Prasad

“…As a result, our review concentrates on the most current scientific and technical progress in the innovation of new antimalarial medications. The protein kinases, choline transport inhibitors, dihydroorotate dehydrogenase inhibitors, isoprenoid biosynthesis inhibitors, and enzymes involved in the metabolism of lipids and replication of deoxyribonucleic acid, are among the most fascinating antimalarial target proteins presently being investigated. …”
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Exploring the Infectious Drug Target Glutathione S-Transferase in Plasmodium falciparum with the Inhibitory Potential of Azadirachta indica Phytocompounds by Esam S. Al-Malki

“…Neem’s active ingredients have shown promise as a new class of antimalarial medications. Neem compounds may boost the efficacy of other antimalarial drugs and the host immune system by inhibiting GST, which is involved in the metabolism of the malaria parasite.…”
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Prevalence of glucose-6-phosphate dehydrogenase deficiency in Cameroonian blood donors by Stephanie M. Lauden, Stella Chongwain, Anzeh Achidi, Ethan Helm, Sarah E. Cusick, Amelia Krug, Tina M. Slusher, Troy C. Lund

“…It is frequently found in individuals of African descent in whom it can lead to hemolytic crises triggered by the use of certain antimalarial medications and infection. The prevalence of G6PD deficiency and its contribution to morbidity in West Africa is under-studied. …”
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Protocol for a magnetic resonance imaging study of participants in the fever RCT: Does fever control prevent brain injury in malaria? by Moses B Chilombe, Karl B Seydel, Colleen A Hammond, Suzanna Mwanza, Archana A Patel, Frank Lungu, Somwe Wa Somwe, Sam Kampondeni, Michael J Potchen, Michael P McDermott, Gretchen L Birbeck

“…<h4>Background</h4>Despite eradication efforts, ~135,000 African children sustained brain injuries as a result of central nervous system (CNS) malaria in 2021. Newer antimalarial medications rapidly clear peripheral parasitemia and improve survival, but mortality remains high with no associated decline in post-malaria neurologic injury. …”
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Sensitivity and specificity of molecular methods for detecting markers of antimalarial drug resistance in clinical samples of Plasmodium falciparum: a systematic review by Burrow, R

“…Resistance to different antimalarial medications continues to develop and spread, threatening effective prophylaxis and treatment. …”