Discovering Tuberosin and Villosol as Potent and Selective Inhibitors of AKT1 for Therapeutic Targeting of Oral Squamous Cell Carcinoma by Mohd Adnan, Deeba Shamim Jairajpuri, Muskan Chaddha, Mohd Shahnawaz Khan, Dharmendra Kumar Yadav, Taj Mohammad, Abdelbaset Mohamed Elasbali, Waleed Abu Al-Soud, Salem Hussain Alharethi, Md. Imtaiyaz Hassan

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Diet-Related Inflammation is Associated with Major Depressive Disorder in Bahraini Adults: Results of a Case-Control Study Using the Dietary Inflammatory Index by Chen W, Faris AIE, Bragazzi NL, AlGahtani HMS, Saif Z, Jahrami A, Shivappa N, Hebert JR, Jahrami H

“…Wen Chen,1 Mo’ez Al-Islam E Faris,2 Nicola Luigi Bragazzi,3 Haifa MS AlGahtani,4,5 Zahra Saif,6 Ahmed Jahrami,7 Nitin Shivappa,8,9 James R Hebert,8,9 Haitham Jahrami4,6 1Department of Psychiatry, Xiamen Xianyue Hospital, Xiamen, 361000, People’s Republic of China; 2Department of Clinical Nutrition and Dietetics, College of Health Sciences/Research Institute for Medical and Health Sciences (RIMHS), University of Sharjah, Sharjah, United Arab Emirates; 3Laboratory for Industrial and Applied Mathematics (LIAM), Department of Mathematics and Statistics, York University, Toronto, ON, Canada; 4College of Medicine and Medical Sciences, Arabian Gulf University, Manama, Bahrain; 5Renewal and Reward Center, Dammam, Saudi Arabia; 6Ministry of Health, Manama, Bahrain; 7Bahraini Association for Intellectual Disabilities and Autism, Sanad, Bahrain; 8Cancer Prevention and Control Program, University of South Carolina, Columbia, SC, 29208, USA; 9Department of Epidemiology and Biostatistics, Arnold School of Public Health, University of South Carolina, Columbia, SC, USACorrespondence: Haitham JahramiMinistry of Health, PO Box 12, Manama, BahrainTel +973 17286334Fax +973 17286335Email hjahrami@health.gov.bhPurpose: This case-control study aimed to examine the association between the inflammation potential of the diet and depression.Patients and Methods: Ninety-six patients with major depression disorder were matched with 96 age- and sex-matched healthy controls. …”
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How does cognitive function measured by the reaction time and critical flicker fusion frequency correlate with the academic performance of students? by Archana Prabu Kumar, Abirami Omprakash, Maheshkumar Kuppusamy, Maruthy K.N., Sathiyasekaran B.W.C., Vijayaraghavan P.V., Padmavathi Ramaswamy

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Identifying psychosocial problems, needs, and coping mechanisms of adolescent Syrian refugees in Jordan by Tariq N. Al-Shatanawi, Yousef Khader, Husam ALSalamat, Husam ALSalamat, Lourance Al Hadid, Alaa Jarboua, Basil Amarneh, Osama Alkouri, Mahmoud A. Alfaqih, Mahmoud A. Alfaqih, Nasr Alrabadi

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An experimental vignette study to assess stigmatized attitudes towards tobacco smokers in Kuwait by Shouq Al Dharman, Kawthar Safar, Fatima Al Enezi, Hessa Al Bahar, Alaa Ali, Zahra Al Qallaf, Athoub Al Shaya, Maryam Alenezi, Safiyah Al Otaibi, Maryam Al Nassar, Zainab Mohammad, Salman Alzayani

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Guidelines for acute management of hyperammonemia in the Middle East region by Alfadhel M, Al Mutairi F, Makhseed N, Al Jasmi F, Al-Thihli K, Al-Jishi E, AlSayed M, Al-Hassnan ZN, Al-Murshedi F, Häberle J, Ben-Omran T

“…Majid Alfadhel,1,2 Fuad Al Mutairi,1,2 Nawal Makhseed,3 Fatma Al Jasmi,4 Khalid Al-Thihli,5 Emtithal Al-Jishi,6 Moeenaldeen AlSayed,7 Zuhair N Al-Hassnan,7,8 Fathiya Al-Murshedi,5 Johannes Häberle,9 Tawfeg Ben-Omran10 Middle East Hyperammonemia and Urea Cycle Disorders Scientific Group (MHUSG) 1Department of Pediatrics, Division of Genetics, 2King Saud bin Abdulaziz University for Health Sciences, King Abdulaziz Medical City, Riyadh, Saudi Arabia; 3Department of Pediatrics, Jahra Hospital, Ministry of Health, Jahra City, Kuwait; 4Department of Pediatric, College of Medicine and Health Sciences, United Arab Emirates University, Al-Ain, United Arab Emirates; 5Genetic and Developmental Medicine Clinic, Sultan Qaboos University Hospital, Muscat, Sultanate of Oman; 6Salmaniya Medical Complex, Arabian Gulf University, Manama, Bahrain; 7Department of Medical Genetics, King Faisal Specialist Hospital & Research Center, 8The National Newborn Screening Program, Ministry of Health, Riyadh, Saudi Arabia; 9Department of Pediatrics, Division of Metabolism and Children’s Research Center, University Children’s Hospital Zurich, Zurich, Switzerland; 10Division of Clinical and Metabolic Genetics, Department of Pediatrics, Hamad Medical Corporation, Doha, Qatar Background: Hyperammonemia is a life-threatening event that can occur at any age. …”
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Pain frequency, severity and QT dispersion in adult patients with sickle cell anemia: correlation with inflammatory markers by Garadah TS, Jaradat AA, AlAlawi ME, Hassan AB, Sequeira RP

“…Taysir S Garadah,1,2 Ahmed A Jaradat,2 Mohammed E AlAlawi,1 Adla B Hassan,1 Reginald P Sequeira2 1Salmanyia Medical Complex, Ministry of Health, 2College of Medicine and Medical Sciences, Arabian Gulf University, Manama, Kingdom of Bahrain Background: Inflammatory markers are increased during vaso-occlusive crisis (VOC) in adult patients with sickle cell anemia (SCA), but this is not clear in clinical steady state. …”
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Development and Validation of the Motivation for Tutoring Questionnaire in Problem-Based Learning Programs by Salah Eldin Kassab, Nahla Hassan, Shimaa El-Araby, Abdel Halim Salem, Saleh Ali Alrebish, Ahmed S. Al-Amro, Hani A. Al-Shobaili, Hossam Hamdy

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Programmed Death-Ligand 1 Expression in Breast Cancer Patients: Clinicopathological Associations from a Single-Institution Study by Ayoub NM, Fares M, Marji R, Al Bashir SM, Yaghan RJ

“…Nehad M Ayoub,1 Mona Fares,1 Raya Marji,2 Samir M Al Bashir,2 Rami J Yaghan3 1Department of Clinical Pharmacy, Faculty of Pharmacy, Jordan University of Science and Technology (JUST), Irbid, 22110, Jordan; 2Department of Pathology and Microbiology, Faculty of Medicine, Jordan University of Science and Technology, Irbid, 22110, Jordan; 3Department of Surgery, College of Medicine and Medical Sciences, Arabian Gulf University, Manama, BahrainCorrespondence: Nehad M AyoubDepartment of Clinical Pharmacy, Faculty of Pharmacy, Jordan University of Science and Technology (JUST), Irbid, 22110, JordanTel +962-2-7201000 Ext. 23809Fax +962-2-7095123Email nmayoub@just.edu.joPurpose: Tumor expression of programmed death-ligand 1 (PD-L1) is associated with evasion of immune response in several types of malignancies and such expression may render patients eligible for PD-L1 inhibitors. …”
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QTc Interval and QT Dispersion in Patients with Thalassemia Major: Electrocardiographic (EKG) and Echocardiographic Evaluation by Taysir S. Garadah, Salah Kassab, Najat Mahdi, Ahmed Abu-Taleb, Anwer Jamsheer

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Cheese Intake Exhibits an Alteration of Glycolipid Profile and Impacts on Non-Alcoholic Fatty Liver in Bahraini Older Adults by Simone Perna, Layla H. Hammad, Mohamed Wael Mohamed, Dalal Alromaihi, Mariam Alhammadi, Noora Al-Khater, Anas Rashed Alchuban, Mawadh Ali Aledrisy, Zahra Ilyas, Tariq A. Alalwan, Mariangela Rondanelli

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The psychometric properties of the Arabic version of the dieting beliefs scale (DBS) by Salma Yasser Abu-Saleh, Wajiha Irsheid, Hadeel Ghazzawi, Adam Tawfiq Amawi, Seithikurippu R. Pandi-Perumal, Khaled Trabelsi, Mary V. Seeman, Haitham Jahrami

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Barriers experienced by community midwives to provide basic emergency obstetric and newborn care in rural Pakistan by Ramesh Kumar, Vikram Mehraj, Jamil Ahmed, Shahzad Ali Khan, Tariq Mehmood Ali, Saima Batool, Fozia Rashid, Sathirakorn Pongpanich

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Religious fasting and its impacts on individual, public, and planetary health: Fasting as a “religious health asset” for a healthier, more equitable, and sustainable society by Khaled Trabelsi, Khaled Trabelsi, Achraf Ammar, Achraf Ammar, Mohamed Ali Boujelbane, Luca Puce, Sergio Garbarino, Egeria Scoditti, Omar Boukhris, Omar Boukhris, Saber Khanfir, Cain C. T. Clark, Jordan M. Glenn, Omar A. Alhaj, Haitham Jahrami, Haitham Jahrami, Hamdi Chtourou, Nicola Luigi Bragazzi

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Gender differences in waterpipe tobacco smoking among university students in four Eastern Mediterranean countries by Randah R. Hamadeh, Juhan Lee, Niveen M. E. Abu-Rmeileh, Muhammad Darawad, Aya Mostafa, Khalid A. Kheirallah, Afzalhussein Yusufali, Justin Thomas, Mohamed Salama, Rima Nakkash, Ramzi G. Salloum

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Harm perceptions of waterpipe tobacco smoking among university students in five Eastern Mediterranean Region countries: A cross-sectional study by Niveen M.E. Abu-Rmeileh, Ola Alkhuffash, Khalid Kheirallah, Aya Mostafa, Muhammad Darawad, Yahya Al-Farsi, Afzalhussein Yusufali, Justin Thomas, Mohamed Salama, Randah R. Hamadeh, Rima Nakkash, Ramzi G. Salloum

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Optimizing Short-Term Maximal Exercise Performance: The Superior Efficacy of a 6 mg/kg Caffeine Dose over 3 or 9 mg/kg in Young Female Team-Sports Athletes by Houda Bougrine, Achraf Ammar, Atef Salem, Khaled Trabelsi, Haitham Jahrami, Hamdi Chtourou, Nizar Souissi

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Isorhamnetin Reduces Glucose Level, Inflammation, and Oxidative Stress in High-Fat Diet/Streptozotocin Diabetic Mice Model by Abdelrahim Alqudah, Esam Y. Qnais, Mohammed A. Wedyan, Sara Altaber, Yousra Bseiso, Muna Oqal, Rawan AbuDalo, Khaled Alrosan, Amjad Z. Alrosan, Suhad Bani Melhim, Mohammad Alqudah, Rabaa Y. Athamneh, Omar Gammouh

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Pulsed and Tissue Doppler Echocardiographic Changes in Patients with Thalassemia Major by Taysir S. Garadah, Salah Kassab, Najat Mahdi, Ahmed Abu-Taleb, Anwer Jamsheer

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Influenza vaccine uptake in Tunisia from two high-risk groups’ perception and attitudes: a qualitative study by Aicha Boukthir, Aicha Boukthir, Hind Bouguerra, Hind Bouguerra, Afif Ben Salah, Afif Ben Salah, Astrid C. Erber, Astrid C. Erber, Sana Chaabene, Hayet Moussa, François Guillemette, Nissaf Ben Alaya, Nissaf Ben Alaya, Jihene Bettaieb, Jihene Bettaieb

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