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4021
Cellular Senescence as the Pathogenic Hub of Diabetes-Related Wound Chronicity
Published 2020-09-01“…This society may be fostered by a diabetic archetypal secretome that induces replicative senescence in dermal fibroblasts, endothelial cells, and keratinocytes. …”
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4022
Hypervirulent <i>Klebsiella pneumoniae</i> Sequence Type 420 with a Chromosomally Inserted Virulence Plasmid
Published 2021-08-01“…The latter was supported by the clinical appearance and our phenotypic findings revealing increased siderophore production and hypermucoviscosity similar to an archetypical, hypervirulent <i>K. pneumoniae</i> strain. …”
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4023
Diagnostic Value of JC Polyomavirus Viruria, Viremia, Serostatus and microRNA Expression in Multiple Sclerosis Patients Undergoing Immunosuppressive Treatment
Published 2022-01-01“…The viral load in urine and plasma from the MS cohort increased over time, mostly pronounced in natalizumab-treated patients, whereas it persisted in HC. The archetypal NCCR was detected in all positive urine, whereas mutations were observed in plasma-derived NCCRs resulting in a more neurotropic variant. …”
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4024
Biodegradable system for drug delivery of hydrolytically labile azanucleoside drugs
Published 2016-06-01“…Background: The archetypal DNA methyltransferase inhibitors, 5-azacytidine (AZA) and 5-aza-2'-deoxycytidine (DAC) are potent antineoplastic agents used in the treatment of mainly, blood malignancies. …”
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4025
Unveiling the Role of Capping Groups in Naphthalene N-Capped Dehydrodipeptide Hydrogels
Published 2023-06-01“…Self-assembled peptide-based hydrogels are archetypical nanostructured materials with a plethora of foreseeable applications in nanomedicine and as biomaterials. …”
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4026
A data-derived reference mixture representative of European wastewater treatment plant effluents to complement mixture assessment
Published 2023-09-01“…The approach presented can furthermore serve as a roadmap guiding the development of archetypic background mixtures for other sources, geographical settings and chemical compounds, e.g. inorganic pollutants.…”
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4027
Not with a “zap” but with a “beep”: Measuring the origins of perinatal experience
Published 2023-06-01“…While newborn infants are the archetypal subjects for studying early human development, researchers may also benefit from fetal studies, as the womb is, in many respects, a more controlled environment than the cradle. …”
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4028
First Results from the JWST Early Release Science Program Q3D: Ionization Cone, Clumpy Star Formation, and Shocks in a z = 3 Extremely Red Quasar Host
Published 2023-01-01“…The JWST observations simultaneously reveal an archetypal rapidly forming massive galaxy undergoing a merger, a clumpy starburst, an episode of obscured near-Eddington quasar activity, and an extremely powerful quasar outflow.…”
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4029
Disrupting the LC3 Interaction Region (LIR) Binding of Selective Autophagy Receptors Sensitizes AML Cell Lines to Cytarabine
Published 2020-03-01“…In order to generate tools to study LIRs in cells, we engineered high affinity binders of LIR motifs of three archetypical SARs: OPTN, p62, and NDP52. In an array of in vitro and cellular assays, the engineered binders were shown to have greatly improved affinity and specificity when compared with the endogenous LC3/GABARAP family of proteins, thus providing a unique possibility for modulating LIR interactions in living systems. …”
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4030
Analysis of Drawings on Representations of COVID-19 among Senior High School Students: Case of the Dakhla-Oued Eddahab Region, Morocco
Published 2022-12-01“…The findings show that the majority of the students knew the archetypal representation of COVID-19. They had a good grasp of the COVID-19, how it spreads, and how to stop it from spreading. …”
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4031
Insights into Activation Mechanisms of Store-Operated TRPC1 Channels in Vascular Smooth Muscle
Published 2020-01-01“…It is therefore important that we understand the biophysical, molecular composition, activation pathways, and physiological significance of SOCs in VSMCs as these maybe future therapeutic targets for conditions such as hypertension and atherosclerosis. Archetypal SOCs called calcium release-activated channels (CRACs) are composed of Orai1 proteins and are stimulated by the endo/sarcoplasmic reticulum Ca<sup>2+</sup> sensor stromal interaction molecule 1 (STIM1) following store depletion. …”
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4032
De-Suppression of Mesenchymal Cell Identities and Variable Phenotypic Outcomes Associated with Knockout of <i>Bbs1</i>
Published 2023-11-01“…Bardet–Biedl syndrome (BBS) is an archetypal ciliopathy caused by dysfunction of primary cilia. …”
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4033
A novel transcriptional signature identifies T-cell infiltration in high-risk paediatric cancer
Published 2023-04-01“…Furthermore, we explored transcriptional features of immune archetypes and T-cell receptor sequencing diversity, assessed the relationship between CD8+ and CD4+ abundance by IHC and deconvolution predictions and assessed the common adult biomarkers such as neoantigen load and TMB. …”
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4034
The discovery of y dwarfs using data from the wide-field infrared survey explorer (WISE)
Published 2013“…The spectrum of WISEP J182831.08+265037.8 is distinct in that the heights of the J- and H-band peaks are approximately equal in units of f [subscript λ], so we identify it as the archetypal member of the Y spectral class. The spectra of at least two of the other brown dwarfs exhibit absorption on the blue wing of the H-band peak that we tentatively ascribe to NH[subscript 3]. …”
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4035
Green infrastructure development as education for sustainable development model in Universiti Malaysia Sabah
Published 2017“…The selected roof area was originally built as an observatory area but was found to have an archetypal problem associated with the urban environment: absence of vegetation, intense solar radiation, and unfit for multifunctional usage. …”
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4036
УКРАЇНСЬКІ ПРИСЛІВ’Я І ПРИКАЗКИ ЯК ПСИХОЛІНГВІСТИЧНИЙ РЕСУРС КОГНІТИВНО- ПОВЕДІНКОВОЇ ТЕРАПІЇ ТРИВОЖНИХ РОЗЛАДІВ...
Published 2017-11-01“…Keywords: anxiety disorders, Ukrainian proverbs and sayings, psycholinguistic resource, archetypes, cognitive and behavioral therapy. Засекина Л. …”
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4037
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4038
Phraseological Units with the Word “Bread” in Russian, Frenchand Italian Linguocultures
Published 2020-12-01“…Cultural categories are a kind of stereotypes, symbols, standards, mythologemes, archetypes, rituals and other signs of both national and universal culture. …”
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4039
RhoA Drives T-Cell Activation and Encephalitogenic Potential in an Animal Model of Multiple Sclerosis
Published 2018-05-01“…Our study demonstrates that RhoA is a central regulator of several archetypical T-cell responses, and furthermore points toward RhoA as a new potential therapeutic target in diseases such as MS, where T-cell activity plays a central role.…”
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4040
Bourdieu in Plain Anabaptist Studies? A Symposium Review of Good Gingrich, Luann. 2016. <em>Out of Place: Social Exclusion and Mennonite Migrants in Canada</em>. Toronto, ON: Unive...
Published 2017-12-01“…"<p>Editor’s introduction—This symposium offers the reviews of two authors who, without sparing whatever criticism can be mustered, hold her work up as archetypal for rigorous methods and theory in plain Anabaptist studies. …”
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