Characterization of Fungal FAD-Dependent AA3_2 Glucose Oxidoreductases from Hitherto Unexplored Phylogenetic Clades by Sudarma Dita Wijayanti, Leander Sützl, Adèle Duval, Dietmar Haltrich

“…Overall, the newly studied AA3_2 glucose oxidoreductases showed a much broader substrate spectrum than the archetypal GOx from <i>Aspergillus niger</i>, which belongs to clade GOx I.…”
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NIR‐emitting Electrochromic Windows for Cold Climate Region Buildings by Dr. Daniela Pinheiro, Dr. Mariana Fernandes, Dr. Rui F. P. Pereira, Dr. Sónia Pereira, Dr. Sandra F. H. Correia, Prof. Dr. M. Manuela Silva, Prof. Dr. Elvira Fortunato, Prof. Dr. Rute A. S. Ferreira, Prof. Dr. Maria Cristina Gonçalves, Prof. Dr. Verónica deZea Bermudez

“…The first electro‐optical tests, performed in 2019, with an archetypal ECD including amorphous tungsten oxide and crystalline nickel oxide as EC layers, a‐IZO as outermost layers, and d‐Ut(600)400Er(tta)3(H2O)2[Bmim]Cl (400 is the molar ratio of oxyethylene units/Er3+ ion) as the electrolyte, demonstrated rather low coloration efficiency (CEin/CEout) values of −4/+6 cm2 C−1 at 555 nm. …”
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Aggressive uveal melanoma displays a high degree of centrosome amplification, opening the door to therapeutic intervention by Dorota Sabat‐Pośpiech, Kim Fabian‐Kolpanowicz, Helen Kalirai, Natalie Kipling, Sarah E Coupland, Judy M Coulson, Andrew B Fielding

“…Phenotypic analysis of patient‐derived cultures and established UM lines revealed comparable levels of centrosome amplification in PUM cells to archetypal triple‐negative breast cancer cell lines, whilst metastatic UM (MUM) cell lines had even higher levels. …”
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Ten Steps to Design a Counseling App to Reduce the Psychosocial Impact of Human Papillomavirus Testing on the Basis of a User-Centered Design Approach in a Low- and Middle-Income S... by Victoria Sánchez Antelo, Lucila Szwarc, Anabella Le Pera, Paula Fredjkes, Diana Saimovici, Silvia Massaccesi, Melisa Paolino, Kasisomayajula Viswanath, Silvina Arrossi

“…We also discussed the critical challenges and the strategies to address them.RESULTSThe steps are (1) knowledge, attitudes, and beliefs mapping: reanalysis of team's research findings from prior studies; (2) environmental scanning of apps available on the market; (3) stakeholders' point of view: The International Advisory Committee; (4) potential user's profile: building archetypes through the Persona method; (5) women's interviews: user's preferences and experiences; (6) effective features: scoping review to select app's features that address psychosocial impact; (7) the user journey: ideal interaction with the gynecological service and the counseling app; (8) women's focus groups: using Personas and Scenarios to discuss app's mock-up; (9) women's design sessions: prototype test and card-sorting techniques; and (10) team's design session: translating results into visual objects and features.CONCLUSIONWe provide here detailed descriptions of the UCD process of an app for human papillomavirus–tested women for those venturing into the area of mHealth strategies work. …”
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Comparative study of Hadarat-e khams in viewpoints of Gheisari & Imam Khomeini by Seyed Mahmoud Yousefsani, Hossein Zahmatkesh Zanjani

“…Keywords used by Gheisari include: the stages of divine essence, absolute hidden, external levels, the world of multiplicity, divine names and attributes, permanent archetypes, worlds of Mesali (the likes or examples), perfect man, Mohammadian truth. 4. …”
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Genotyping of polymorphic effectors of Toxoplasma gondii isolates from China by Weisheng Cheng, Cong Wang, Ting Xu, Fang Liu, Faustina Pappoe, Qingli Luo, Yuanhong Xu, Fangli Lu, Jilong Shen

“…Little has been known about these molecules as well as GRA3 in type Chinese 1 strains that show polymorphism among strains of archetypical genotypes. This study examined the genetic diversity of these effectors and its correlated virulence in mice among T. gondii isolates from China. …”
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Normal tissue homeostasis and impairment of selective inflammatory responses in dendritic cells deficient for ATF6α by Francisca Gutiérrez-Ballesteros, Jonathan Morales-Reyes, Dominique Fernández, Antonia Geisse, Amada Arcaya, Felipe Flores-Santibañez, María Rosa Bono, Fabiola Osorio

“…Sensors of the unfolded protein response (UPR) of the endoplasmic reticulum, a three-pronged signaling pathway that maintains the fidelity of the cellular proteome, have emerged as regulators of DC biology. The archetypical example is the IRE1/XBP1s axis, which supports DC development and survival of the conventional type 1 DC (cDC1) subtype. …”
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Synthesis, Characterization and Biological Studies of Ether–Based Ferrocenyl Amides and their Organic Analogues by Sana Waseem Abbasi, Naveed Zafar Ali, Martin Etter, Muhammad Shabbir, Zareen Akhter, Stacey J. Smith, Hammad Ismail, Bushra Mirza

“…Spectral studies confirmed the presence of amide linkages in the synthesised compound with a strong N—H·····O=C hydrogen bonding network established between amide groups of neighbouring molecular scaffolds further stabilising the molecular stacking in accordance with the archetypal crystal structures. The bioactive nature of each compound was assessed by DPPH (2,2-diphenyl-1-picrylhydrazyl) free radical scavenging activity, hydrogen peroxide scavenging activity and total antioxidant activity. …”
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Molecular Insights into Defense Responses of Vietnamese Maize Varieties to <i>Fusarium verticillioides</i> Isolates by Trang Minh Tran, Maarten Ameye, Sofie Landschoot, Frank Devlieghere, Sarah De Saeger, Mia Eeckhout, Kris Audenaert

“…Moreover, little information is currently available on the involvement of the archetypal defense pathways in the <i>F. verticillioides</i>–maize interaction using local isolates and germplasm, respectively. …”
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Pleomorphic xanthoastrocytoma is a heterogeneous entity with pTERT mutations prognosticating shorter survival by Azadeh Ebrahimi, Andrey Korshunov, Guido Reifenberger, David Capper, Joerg Felsberg, Elena Trisolini, Bianca Pollo, Chiara Calatozzolo, Marco Prinz, Ori Staszewski, Leonille Schweizer, Jens Schittenhelm, Patrick N. Harter, Werner Paulus, Christian Thomas, Patricia Kohlhof-Meinecke, Marcel Seiz-Rosenhagen, Till Milde, Belén M. Casalini, Abigail Suwala, Annika K. Wefers, Annekathrin Reinhardt, Philipp Sievers, Christof M. Kramm, Nima Etminam, Andreas Unterberg, Wolfgang Wick, Christel Herold-Mende, Dominik Sturm, Stefan M. Pfister, Martin Sill, David T. W. Jones, Daniel Schrimpf, David E. Reuss, Ken Aldape, Zied Abdullaev, Felix Sahm, Andreas von Deimling, Damian Stichel

“…Histological approach to diagnosis will predominantly identify cases with the established archetypical morphology. DNA methylation analysis includes additional tumors in the tumor class PXA that share similar DNA methylation profile but lack the typical morphology of a PXA. …”
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TLR7 Protein Expression in Mild and Severe Lupus-Prone Models Is Regulated in a Leukocyte, Genetic, and IRAK4 Dependent Manner by Teja Celhar, Hao Kim Lu, Lia Benso, Larissa Rakhilina, Hui Yin Lee, Hui Yin Lee, Shubhita Tripathi, Shubhita Tripathi, Olga Zharkova, Olga Zharkova, Wei Yee Ong, Hiroko Yasuga, Hiroko Yasuga, Bijin Au, Damien Marlier, Lina Hsiu Kim Lim, Thomas Paulraj Thamboo, John S. Mudgett, Matthew F. Mackey, Dennis M. Zaller, John E. Connolly, John E. Connolly, Anna-Marie Fairhurst, Anna-Marie Fairhurst, Anna-Marie Fairhurst, Anna-Marie Fairhurst

“…Systemic lupus erythematosus (SLE) is the archetypical autoimmune disease, affecting multiple organs, and tissues. …”
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Estimating the future global dose demand for measles–rubella microarray patches by Melissa Ko, Stefano Malvolti, Thomas Cherian, Carsten Mantel, Robin Biellik, Courtney Jarrahian, Marion Menozzi-Arnaud, Jean-Pierre Amorij, Hans Christiansen, Mark J. Papania, Martin I. Meltzer, Balcha Girma Masresha, Desiree Pastor, David N. Durrheim, Birgitte Giersing, Mateusz Hasso-Agopsowicz

“…A demand forecast analysis of the programmatic doses required (PDR) could accelerate MR-MAP development by informing the size and return of the investment required to manufacture MAPs.MethodsUnconstrained global MR-MAP demand for 2030–2040 was estimated for three scenarios, for groups of countries with similar characteristics (archetypes), and four types of uses of MR-MAPs (use cases). …”
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Potential and limitations of crowdsourced data for high-resolution rice mapping in Madagascar: The importance of representation by Koen De Vos, Benjamin Campforts, Laurent Tits, Kristof Van Tricht, Kasper Bonte, Gerard Govers, Liesbet Jacobs

“…On the other hand, geotagged pictures from social media, which do document rice production areas, predominantly represent 'scenic' fields appealing to social media contributors, i.e. irrigated, intensive rice production systems. The archetypal nature of these data leads to distinct feature signatures. …”
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Epigenetic impacts of stress priming of the neuroinflammatory response to sarin surrogate in mice: a model of Gulf War illness by David G. Ashbrook, Benjamin Hing, Lindsay T. Michalovicz, Kimberly A. Kelly, Julie V. Miller, Wilfred C. de Vega, Diane B. Miller, Gordon Broderick, James P. O’Callaghan, Patrick O. McGowan

“…Abstract Background Gulf War illness (GWI) is an archetypal, medically unexplained, chronic condition characterised by persistent sickness behaviour and neuroimmune and neuroinflammatory components. …”
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Getting to net zero: Islington’s social housing stock by Stephen Evans, Daniel Godoy-Shimizu, Philip Steadman, Shyam Amrith, Dominic Humphrey, Paul Ruyssevelt

“…The modelling did not rely on ‘archetypes’ as in many such studies. Realistic retrofit options were analysed in each case, using current cost data from practitioners. …”
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Acclimation of liverwort Marchantia polymorpha to physiological drought reveals important roles of antioxidant enzymes, proline and abscisic acid in land plant adaptation to osmoti... by Totan Kumar Ghosh, Naznin Haque Tompa, Md. Mezanur Rahman, Mohammed Mohi-Ud-Din, S. M. Zubair Al-Meraj, Md. Sanaullah Biswas, Mohammad Golam Mostofa

“…Furthermore, the application of exogenous abscisic acid (ABA) reduced drought-induced tissue damage and improved the activities of antioxidant enzymes and accumulation of proline, implying an archetypal role of this phytohormone in M. polymorpha for drought tolerance. …”
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Tiger reefs: Self‐organized regular patterns in deep‐sea cold‐water coral reefs by Anna‐Selma van derKaaden, Sandra R. Maier, Koen Siteur, Laurence H. De Clippele, Johan van deKoppel, Sam J. Purkis, Max Rietkerk, Karline Soetaert, Dick vanOevelen

“…Self‐organized ecosystems are well‐known from the terrestrial realm, with “tiger bushes” being the archetypical example and mussel beds and tropical coral reefs the marine examples. …”
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Extremely Potent Block of Bacterial Voltage-Gated Sodium Channels by µ-Conotoxin PIIIA by Rocio K. Finol-Urdaneta, Jeffrey R. McArthur, Vyacheslav S. Korkosh, Sun Huang, Denis McMaster, Robert Glavica, Denis B. Tikhonov, Boris S. Zhorov, Robert J. French

“…&#181;-Conotoxin PIIIA, in the sub-picomolar, range inhibits the archetypal bacterial sodium channel NaChBac (NavBh) in a voltage- and use-dependent manner. …”
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Composition of gastrointestinal microbiota in association with treatment response in individuals with metastatic castrate resistant prostate cancer progressing on enzalutamide and... by Lauren B. Peiffer, James R. White, Carli B. Jones, Rachel E. Slottke, Sarah E. Ernst, Amy E. Moran, Julie N. Graff, Karen S. Sfanos

“…However, certain bacterial taxa identified by sequencing across multiple 16S rRNA hypervariable regions were consistently associated with response, including the archetypal oral bacterium Streptococcus salivarius. …”
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Carbon and nutrient export regimes from headwater catchments to downstream reaches by R. Dupas, R. Dupas, A. Musolff, J. W. Jawitz, P. S. C. Rao, C. G. Jäger, J. H. Fleckenstein, M. Rode, D. Borchardt

“…Three headwater catchments were selected as archetypes of the main landscape units (land use  ×  lithology) present in the Selke catchment. …”
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