Argonaute Proteins: Why Are They So Important for the Legume–Rhizobia Symbiosis? by Oswaldo Valdés-López, Damien Formey, Mariel C. Isidra-Arellano, Mariel C. Isidra-Arellano, Maria del Rocio Reyero-Saavedra, Tadeo F. Fernandez-Göbel, Maria del Socorro Sánchez-Correa

Subjects: “…argonaute proteins…”
Get full text

Argonaute2 is essential for mammalian gastrulation and proper mesoderm formation. by Reid S Alisch, Peng Jin, Michael Epstein, Tamara Caspary, Stephen T Warren

“…Mammalian Argonaute proteins (EIF2C1-4) play an essential role in RNA-induced silencing. …”
Get full text

A primary sequence analysis of the ARGONAUTE protein family in plants. by Daniel Rodriguez-Leal, Amanda Castillo-Cobián, Isaac Rodriguez-Arévalo, Jean-Philippe Vielle-Calzada

Subjects: Get full text

DNA interference and beyond: structure and functions of prokaryotic Argonaute proteins by Lidiya Lisitskaya, Alexei A. Aravin, Andrey Kulbachinskiy

“…In this review, Aravin and colleagues examine bacterial and archaeal Argonaute proteins, discuss their diverse architectures and their possible roles in host defense, proposing additional functions for Argonaute proteins in prokaryotic cells.…”
Get full text

Roles of Argonautes and Dicers on Sclerotinia sclerotiorum Antiviral RNA Silencing by Achal Neupane, Chenchen Feng, Pauline K. Mochama, Huma Saleem, Shin-Yi Lee Marzano, Shin-Yi Lee Marzano

Subjects: Get full text

Argonaute identity defines the length of mature mammalian microRNAs by Makeyev, Eugene V., Juvvuna, Prasanna Kumar, Khandelia, Piyush, Lee, Li Ming

“…However, the slicing mode of the miRNA-programmed AGO2 is rarely realized in vivo and the four Argonautes are thought to play largely overlapping roles in the mammalian miRNA pathway. …”
Get full text
Get full text

Argonaute2 mediates compensatory expansion of the pancreatic β cell. by Tattikota, S, Rathjen, T, McAnulty, S, Wessels, H, Akerman, I, van de Bunt, M, Hausser, J, Esguerra, J, Musahl, A, Pandey, A, You, X, Chen, W, Herrera, P, Johnson, P, O'Carroll, D, Eliasson, L, Zavolan, M, Gloyn, A, Ferrer, J, Shalom-Feuerstein, R, Aberdam, D, Poy, M

“…Reduction of miR-184 promotes the expression of its target Argonaute2 (Ago2), a component of the microRNA-induced silencing complex. …”

Argonaute2 mediates compensatory expansion of the pancreatic β cell by Tattikota, S, Rathjen, T, McAnulty, S, Wessels, H, Akerman, I, Van De Bunt, M, Hausser, J, Esguerra, J, Musahl, A, Pandey, A, You, X, Chen, W, Herrera, P, Johnson, P, O'Carroll, D, Eliasson, L, Zavolan, M, Gloyn, A, Ferrer, J, Shalom-Feuerstein, R, Aberdam, D, Poy, M

“…Reduction of miR-184 promotes the expression of its target Argonaute2 (Ago2), a component of the microRNA-induced silencing complex. …”

Argonaute bypasses cellular obstacles without hindrance during target search by Tao Ju Cui, Misha Klein, Jorrit W. Hegge, Stanley D. Chandradoss, John van der Oost, Martin Depken, Chirlmin Joo

“…Argonaute protein is loaded with small RNA and scans long stretch of sequences to find complementary target sites. …”
Get full text

Structural basis for the recognition of guide RNA and target DNA heteroduplex by Argonaute by Tomohiro Miyoshi, Kosuke Ito, Ryo Murakami, Toshio Uchiumi

“…Argonaute proteins are important in the silencing machinery with some regulatory RNAs. …”
Get full text

Mechanistic Insights into the Protection Effect of Argonaute–RNA Complex on the HCV Genome by Haiming Zhuang, Dong Ji, Jigang Fan, Mingyu Li, Ran Tao, Kui Du, Shaoyong Lu, Zongtao Chai, Xiaohua Fan

Subjects: “…argonaute…”
Get full text

Prokaryotic Argonaute from Archaeoglobus fulgidus interacts with DNA as a homodimer by Edvardas Golovinas, Danielis Rutkauskas, Elena Manakova, Marija Jankunec, Arunas Silanskas, Giedrius Sasnauskas, Mindaugas Zaremba

“…Abstract Argonaute (Ago) proteins are found in all three domains of life. …”
Get full text

Spatial distribution of three ARGONAUTEs regulates the anther phasiRNA pathway by Hinako Tamotsu, Koji Koizumi, Alejandro Villar Briones, Reina Komiya

“…Abstract Argonaute protein (AGO) in association with small RNAs is the core machinery of RNA silencing, an essential mechanism for precise development and defense against pathogens in many organisms. …”
Get full text

Author Correction: Genome-wide identification of Argonautes in Solanaceae with emphasis on potato by Zhen Liao, Kristian Persson Hodén, Ravi Kumar Singh, Christina Dixelius

Get full text

Efficient manipulation of gene expression using Natronobacterium gregoryi Argonaute in zebrafish by Zhangji Dong, Xu Chen, Run Zhuo, Yuanyuan Li, Zhihao Zhou, Ying Sun, Yan Liu, Mei Liu

“…Abstract Background Natronobacterium gregoryi Argonaute (NgAgo) was found to reduce mRNA without generating detectable DNA double-strand breaks in a couple of endogenous genes in zebrafish, suggesting its potential as a tool for gene knockdown. …”
Get full text

Mesophilic Argonaute-based isothermal detection of SARS-CoV-2 by Xiao Li, Huarong Dong, Xiang Guo, Fei Huang, Xiaoyi Xu, Nuolan Li, Yu Yang, Tianbao Yao, Yan Feng, Qian Liu

“…Therefore, research on the exploration and development of novel nucleases helps to promote specific and sensitive diagnoses. Prokaryotic Argonaute (Ago) proteins exert directed nuclease activity that can target any sequence. …”
Get full text

Sumoylation of human argonaute 2 at lysine-402 regulates its stability. by Umut Sahin, Pierre Lapaquette, Alexandra Andrieux, Guilhem Faure, Anne Dejean

Get full text

Variation and Evolution in the Glutamine-Rich Repeat Region of Drosophila Argonaute-2 by William H. Palmer, Darren J. Obbard

Subjects: “…Argonaute-2…”
Get full text

Anti-miRs competitively inhibit microRNAs in Argonaute complexes. by Daniel J Hogan, Thomas M Vincent, Sarah Fish, Eric G Marcusson, Balkrishen Bhat, B Nelson Chau, Dimitrios G Zisoulis

“…Furthermore, the targeted miRNAs are stable and continue to be associated with Argonaute. Our results suggest that anti-miRs specifically associate with Argonaute-bound miRNAs, preventing association with target mRNAs, which leads to subsequent stabilization and thus increased expression of the targeted mRNAs.…”
Get full text

Aedes aegypti Argonaute 2 controls arbovirus infection and host mortality by Shengzhang Dong, George Dimopoulos

Get full text