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The evolution of animal Argonautes: evidence for the absence of antiviral AGO Argonautes in vertebrates
Published 2017-08-01“…The animal Argonaute superfamily is traditionally grouped into AGO and PIWI Argonautes. …”
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From the Argonauts Mythological Sailors to the Argonautes RNA-Silencing Navigators: Their Emerging Roles in Human-Cell Pathologies
Published 2020-06-01Subjects: “…argonaute proteins…”
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A Prokaryotic Twist on Argonaute Function
Published 2015-02-01Subjects: “…Argonaute…”
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Structure of yeast Argonaute with guide RNA
Published 2013“…The RNA-induced silencing complex, comprising Argonaute and guide RNA, mediates RNA interference. …”
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How to slice: snapshots of Argonaute in action.
Published 2010“…Argonaute is the principal protein component of the mechanisms of RNA silencing, providing anchor sites for the small guide RNA strand and the 'slicer' activity for cleavage of target mRNAs or short passenger RNA strands. …”
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Germlines: Argonautes go full cycle.
Published 2007“…Specific Argonaute proteins and their small RNA targets are important in animal germline development. …”
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ARGONAUTE10 and ARGONAUTE1 regulate the termination of floral stem cells through two microRNAs in Arabidopsis.
Published 2011-03-01“…We also show that both the ubiquitously expressed ARGONAUTE1 (AGO1) gene and its homolog AGO10, which exhibits highly restricted spatial expression patterns, are required to maintain the correct temporal program of floral stem cells. …”
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Argonaute Proteins Take Center Stage in Cancers
Published 2021-02-01Subjects: “…Argonaute…”
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Prokaryotic Argonautes – variations on the RNA interference theme
Published 2014-04-01Subjects: “…Argonaute…”
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New insights into the function of mammalian Argonaute2.
Published 2020-11-01“…However, the recently solved crystallographic structure of Argonaute2 (Ago2) and a high-throughput analysis that used repurposed sequencing techniques has brought us closer to achieving this goal.…”
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DNA recognition by an RNA-guided bacterial Argonaute.
Published 2017-01-01“…Argonaute (Ago) proteins are widespread in prokaryotes and eukaryotes and share a four-domain architecture capable of RNA- or DNA-guided nucleic acid recognition. …”
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Placing the Unplaceable: The Making of Apollonius’ Argonautic Geography
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Lost and Found: Piwi and Argonaute Pathways in Flatworms
Published 2021-05-01“…These phyla-specific Argonautes showed lower sequence conservation compared to other Argonaute proteins, suggesting that they might have been subjected to high evolutionary rates. …”
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Beyond Loading: Functions of Plant ARGONAUTE Proteins
Published 2023-11-01Subjects: “…ARGONAUTE proteins…”
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Leishmania infection upregulates and engages host macrophage Argonaute 1, and system-wide proteomics reveals Argonaute 1-dependent host response
Published 2023-11-01“…In this study, we investigated the potential role of host macrophage Argonautes in Leishmania pathogenesis. Using Western blot analysis of Leishmania donovani-infected macrophages, we show here that Leishmania infection selectively increased the abundance of host Argonaute 1 (Ago1). …”
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Argonaute protein-based nucleic acid detection technology
Published 2023-09-01Subjects: Get full text
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The Making of a Slicer: Activation of Human Argonaute-1
Published 2013-06-01“…Argonautes are the central protein component in small RNA silencing pathways. …”
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Nuclear Translocation of Argonaute 2 in Cytokine-Induced Senescence
Published 2018-11-01“…Previous studies demonstrated that the growth-repressing state of oncogene-induced senescent cells depends on argonaute protein 2 (Ago2)-mediated transcriptional gene silencing and Ago2/Rb corepression of E2F-dependent cell cycle genes. …”
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