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201
Health sector corruption in the times of COVID-19 pandemic in Bangladesh: Newspapers as mirrors of society
Published 2023-12-01“…Among the measures taken to contain corruption during COVID-19 included filing cases, issuing arrest warrants and asking for submission of wealth statement and source of income of the accused persons. …”
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202
Cytotoxicity and Multi-Enzyme Inhibition of <i>Nepenthes miranda</i> Stem Extract on H838 Human Non-Small Cell Lung Cancer Cells and RPA32, Elastase, Tyrosinase, and Hyaluronidase...
Published 2024-03-01“…Flow cytometry analysis suggested that the stem extract might suppress H838 cell proliferation by inducing G2 cell cycle arrest, thereby inhibiting carcinoma cell proliferation. …”
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203
Association Between Critical Events in the PICU and Outcomes in Neighboring Patients
Published 2022-10-01“…Further studies targeted toward exploring the mechanism behind this effect as well as identification of other nonpatient factors that adversely affect outcomes in children are warranted.…”
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204
Beliefs, attitudes and experiences of virtual overdose monitoring services from the perspectives of people who use substances in Canada: a qualitative study
Published 2023-06-01“…PWUS generally felt optimistic about the potential of VOMS as a suitable harm reduction intervention, but several potential barriers around accessing VOMS were identified that may limit uptake. Future research is warranted.…”
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205
The Role of Selective Flavonoids on Triple-Negative Breast Cancer: An Update
Published 2023-03-01“…Flavonoids are known to have enormous health benefits, such as anticancer, antiviral, anti-inflammatory, and antiallergic properties. They are known to arrest the cell cycle of the tumor cells and induces apoptosis by modulating Bcl-2, Bax, and Caspase activity. …”
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206
Caspase activation counteracts interferon signaling after G2 checkpoint abrogation by ATR inhibition in irradiated human cancer cells
Published 2022-10-01“…Caspase activation thus warrants further consideration as a possible predictive marker for lack of IFN signaling.…”
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207
Identification of a new member of Mortaparib class of inhibitors that target mortalin and PARP1
Published 2022-09-01“…Abrogation of mortalin-p53 interaction and reactivation of p53 has been shown to trigger growth arrest/apoptosis in cancer cells and hence, suggested to be useful in cancer therapy. …”
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208
Design, synthesis, and activity evaluation of 2-iminobenzimidazoles as c-Myc inhibitors for treating multiple myeloma
Published 2024-04-01“…Taken together, our findings suggest that further investigations are warranted for potential therapeutic applications of 5b and 5d for c-Myc-related diseases.…”
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209
Chemical Characterization of Taif Rose (<i>Rosa damascena</i> Mill var. <i>trigentipetala</i>) Waste Methanolic Extract and Its Hepatoprotective and Antioxidant Effects against Cad...
Published 2022-03-01“…Additional in vitro and in vivo studies are warranted.…”
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210
Mitochondrial phosphoenolpyruvate carboxykinase promotes tumor growth in estrogen receptor‐positive breast cancer via regulation of the mTOR pathway
Published 2023-01-01“…Decreased cell proliferation and G0/G1 arrest were induced in ER+ breast cancer cell lines by knockdown of PCK2. …”
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211
Multifaceted Effects of Kinase Inhibitors on Pancreatic Cancer Cells Reveals Pivotal Entities with Therapeutic Implications
Published 2023-06-01“…Therefore, future studies with the two kinases as monotherapy/combination therapy are warranted.…”
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212
Vasopressin versus epinephrine during neonatal cardiopulmonary resuscitation of asphyxiated post-transitional piglets
Published 2023-09-01“…Conclusions: Vasopressin improved post-resuscitation survival and hemodynamics, and might be an alternative cardio-resuscitative medication during neonatal CPR, but further studies are warranted.…”
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213
GA-OH enhances the cytotoxicity of photon and proton radiation in HPV+ HNSCC cells
Published 2023-02-01“…Future research is warranted to further characterize the interaction of GA-OH derivatives and other E6-specific inhibitors with radiation, as well as its potential to improve the safety and effectiveness of radiation treatment for patients with oropharyngeal cancer.…”
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214
Propranolol blocks osteosarcoma cell cycle progression, inhibits angiogenesis and slows xenograft growth in combination with cisplatin-based chemotherapy
Published 2022-09-01“…Further translational studies of propranolol repurposing in osteosarcoma are warranted.…”
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215
Amniotic fluid embolism: an Australian-New Zealand population-based study.
Published 2015“…A potential link between AFE and assisted reproductive technology warrants further investigation.…”
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216
miR-137-mediated loss of KDM5B expression leads to suppression of the malignant phenotype of bladder cancer cells
Published 2014“…We demonstrated that the overexpression of miR-137 significantly attenuated KDM5B expression, induced G1 cell-cycle arrest, suppressed cell growth and blocked invasion and migration of BC cells. …”
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217
LncRNA SNHG5 adversely governs follicular growth in PCOS via miR-92a-3p/CDKN1C axis
Published 2024-02-01“…Additional investigations such as large-scale clinical studies and functional assays are warranted to validate and expand upon these findings.…”
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218
Metformin Enhancement of Therapeutic Effects of 5-Fluorouracil and Oxaliplatin in Colon Cancer Cells and Nude Mice
Published 2022-04-01“…However, further clinical trials are warranted to validate the clinical implications of the findings.…”
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219
p21 as a Predictor and Prognostic Indicator of Clinical Outcome in Rectal Cancer Patients
Published 2024-01-01“…The cell cycle plays a key and complex role in the development of human cancers. p21 is a potent cyclin-dependent kinase inhibitor (CDKI) involved in the promotion of cell cycle arrest and the regulation of cellular senescence. …”
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220
Nelfinavir Induces Cytotoxicity towards High-Grade Serous Ovarian Cancer Cells, Involving Induction of the Unfolded Protein Response, Modulation of Protein Synthesis, DNA Damage, L...
Published 2021-12-01“…Traditional treatment consists of platinum-based therapy; however, rapid development of platinum resistance contributes to lower life expectancy, warranting newer therapies to supplement the current platinum-based protocol. …”
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Article