Early ICD implantation following out-of-hospital cardiac arrest: a retrospective cohort study from the Swedish Registry for Cardiopulmonary Resuscitation by Johan Herlitz, Araz Rawshani, Andreas Martinsson, Cecilia Rorsman, Aidin Rawshani, Pedram Sultanian, Peter Lundgren, Annica Ravn-Fischer, Amar Taha, Anna Myredal, Sebastian Möller, Arash Hadi Jafari, Laura David, Shavan Yassinson

“…Similar associations were noted in all subgroups.Conclusion Among survivors of OHCA, those discharged with an ICD had approximately 60% lower risk of death or recurrent cardiac arrest. A randomised trial is warranted to study this further.…”
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Methanolic neem (Azadirachta indica) stem bark extract induces cell cycle arrest, apoptosis and inhibits the migration of cervical cancer cells in vitro by Saurav Kumar, Vaishali Mulchandani, Jayasri Das Sarma

“…Cell cycle arrest was correlated to transcriptional downregulation of cyclin dependent kinase 1 (CDK1), cyclin A, and cyclin B. …”
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Dillenia Suffruticosa Extract Inhibits Proliferation of Human Breast Cancer Cell Lines (MCF-7 and MDA-MB-231) via Induction of G2/M Arrest and Apoptosis by Maznah Ismail, Norsharina Ismail, Yim Sim Tor, Nurshafini Ishak, Jhi Biau Foo, Intan Safinar Ismail, Latifah Saiful Yazan, Nurdin Armania

“…This warrants further work, especially on the role of hormones in response towards cytotoxic agents. …”
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Psychosocial function, legal involvement and violence in mental disorder by Alec Buchanan, Kelly E. Moore, Brian Pittman, Sherry A. McKee

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Sustained Inflation During Chest Compression: A New Technique of Pediatric Cardiopulmonary Resuscitation That Improves Recovery and Survival in a Pediatric Porcine Model by Georg M. Schmölzer, Siddhi D. Patel, Sveva Monacelli, Seung Yeon Kim, Gyu‐Hong Shim, Tze‐Fun Lee, Megan O'Reilly, Po‐Yin Cheung

“…CC+SI allowed passive ventilation of the lung while providing chest compressions. This technique warrants further studies to examine the potential to improve outcomes in pediatric patients with cardiac arrest. …”
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Hypothyroidism and sinus dysfunction associated with lithium-paliperidone combination therapy for bipolar disorder with psychotic symptoms: a case report by Wenjian Wei, Yonglan Yang, Haifeng Wang, Yunbin Yang, Jizhou Liu, Jizhou Liu, Jinfeng Li

“…Further research is warranted to elucidate the potential risks and benefits of this combination therapy for bipolar disorder with psychotic symptoms.…”
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Dentatin triggers ROS-mediated apoptosis, G0/G1 cell cycle arrest and release of Th1-related cytokines in colorectal carcinoma cells by Ahmad Khusairy Zulpa, Barathan Muttiah, Kumutha Malar Vellasamy, Vanitha Mariappan, Jamuna Vadivelu

“…Further validation of DTN’s mechanism in vivo is warranted.…”
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The association between essential trace element (copper, zinc, selenium, and cobalt) status and the risk of early embryonic arrest among women undergoing assisted reproductive tech... by Yu Cao, Yu Cao, Yu Cao, Yu Cao, Yu Cao, Yu Cao, Chunmei Liang, Chunmei Liang, Chunmei Liang, Chunmei Liang, Chunmei Liang, Chunmei Liang, Chunmei Liang, Lingchao Shen, Lingchao Shen, Lingchao Shen, Lingchao Shen, Lingchao Shen, Lingchao Shen, Zhikang Zhang, Zhikang Zhang, Zhikang Zhang, Zhikang Zhang, Zhikang Zhang, Zhikang Zhang, Tingting Jiang, Danyang Li, Danyang Li, Danyang Li, Danyang Li, Danyang Li, Danyang Li, Weiwei Zou, Jieyu Wang, Jieyu Wang, Jieyu Wang, Jieyu Wang, Jieyu Wang, Jieyu Wang, Kai Zong, Dan Liang, Dan Liang, Dan Liang, Dan Liang, Dan Liang, Dan Liang, Dongmei Ji, Dongmei Ji, Dongmei Ji, Dongmei Ji, Dongmei Ji, Dongmei Ji, Yunxia Cao, Yunxia Cao, Yunxia Cao, Yunxia Cao, Yunxia Cao, Yunxia Cao

“…BackgroundEarly embryonic arrest (EEA) leads to repeated cessation of fresh cycles among infertile women undergoing in vitro fertilization (IVF). …”
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Vitamin D3 Inhibits the Viability of Breast Cancer Cells In Vitro and Ehrlich Ascites Carcinomas in Mice by Promoting Apoptosis and Cell Cycle Arrest and by Impeding Tumor Angiogen... by Prashanth Kumar M. Veeresh, Chaithanya G. Basavaraju, Siva Dallavalasa, Preethi G. Anantharaju, Suma M. Natraj, Olga A. Sukocheva, SubbaRao V. Madhunapantula

“…The generated data warrant further studies on vit-D3 anti-cancer therapeutic applications.…”
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Silybin has therapeutic efficacy against non-small cell lung cancer through targeting of Skp2 by Shi-Bing Zhang, Ming Hong, Xiao-Yang Sun, Da Huang, Dan-Hua He, Yu-Fei Chen, Yong Yuan, Yong-Qiang Liu

“…Thus, SB is a potential Skp2-targeting agent that warrants further clinical investigation.…”
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The associations between rapid response systems and their components with patient outcomes: A scoping review by Rebecca J. Piasecki, Cheryl R. Dennison Himmelfarb, Kelly T. Gleason, Rachel M. Justice, Elizabeth A. Hunt

“…Objective: To explore how recent studies have examined rapid response system components in the context of relevant adverse patient outcomes, such as in-hospital cardiac arrests and hospital mortality. Design: Scoping review. …”
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Dillenia suffruticosa extract inhibits proliferation of human breast cancer cell lines (MCF-7 and MDA-MB-231) via induction of G2/M arrest and apoptosis by Armania, Nurdin, Saiful Yazan, Latifah, Ismail, Intan Safinar, Foo, Jhi Biau, Tor, Yim Sim, Ishak, Nurshafini, Ismail, Norsharina, Ismail, Maznah

“…This warrants further work, especially on the role of hormones in response towards cytotoxic agents. …”
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The Synergistic Cytotoxic Effect of Pentagamavunon-1 (PGV-1) and Curcumin Correlates with the Cell Cycle Arrest to Induce Mitotic Catastrophe in 4T1 and T47D Breast Cancer Cells by Desty Restia Rahmawati, Arief Nurrochmad, Riris Istighfari Jenie, Edy Meiyanto

“…This combination results in cell cycle arrest in the G2/M phase, increased cell accumulation in the sub-G1 phase, and a synergistic increase in mitotic catastrophe. …”
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Extracorporeal cardiopulmonary resuscitation for adult out-of-hospital cardiac arrest patients: time-dependent propensity score-sequential matching analysis from a nationwide popul... by Yeongho Choi, Jeong Ho Park, Joo Jeong, Yu Jin Kim, Kyoung Jun Song, Sang Do Shin

“…Research on how to perform ECPR at an early stage and clinical trials to evaluate the effect of ECPR is warranted.…”
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Triage body temperature and its influence on patients with acute myocardial infarction by Shih-Hao Chen, Hung-Chieh Chang, Po-Wei Chiu, Ming-Yuan Hong, I-Chen Lin, Chih-Chun Yang, Chien-Te Hsu, Chia-Wei Ling, Ying-Hsin Chang, Ya-Yun Cheng, Chih-Hao Lin

“…The primary outcome was in-hospital cardiac arrest (IHCA), while the secondary outcomes were adverse events. …”
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Bromodomain inhibitor i-BET858 triggers a unique transcriptional response coupled to enhanced DNA damage, cell cycle arrest and apoptosis in high-grade ovarian carcinoma cells by Marcos Quintela, David W. James, Agne Pociute, Lydia Powell, Kadie Edwards, Zoe Coombes, Jetzabel Garcia, Neil Garton, Nagindra Das, Kerryn Lutchman-Singh, Lavinia Margarit, Amy L. Beynon, Inmaculada Rioja, Rab K. Prinjha, Nicola R. Harker, Deyarina Gonzalez, R. Steven Conlan, Lewis W. Francis

“…Abstract Background Ovarian cancer has a specific unmet clinical need, with a persistently poor 5-year survival rate observed in women with advanced stage disease warranting continued efforts to develop new treatment options. …”
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Marine Carotenoid Fucoxanthin Possesses Anti-Metastasis Activity: Molecular Evidence by Sukant Garg, Sajal Afzal, Ahmed Elwakeel, Damini Sharma, Navaneethan Radhakrishnan, Jaspreet Kaur Dhanjal, Durai Sundar, Sunil C. Kaul, Renu Wadhwa

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Randomized Trial of 21% versus 100% Oxygen during Chest Compressions Followed by Gradual versus Abrupt Oxygen Titration after Return of Spontaneous Circulation in Neonatal Lambs by Deepika Sankaran, Evan M. Giusto, Amy L. Lesneski, Morgan E. Hardie, Houssam M. Joudi, Emily C. A. Lane, Victoria L. Hammitt, Kirstie C. Tully, Payam Vali, Satyan Lakshminrusimha

“…Clinical studies are warranted to investigate optimal oxygen titration after chest compressions and ROSC during neonatal resuscitation.…”
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<i>Clerodendrum chinense</i> Stem Extract and Nanoparticles: Effects on Proliferation, Colony Formation, Apoptosis Induction, Cell Cycle Arrest, and Mitochondrial Membrane Potentia... by Chuda Chittasupho, Weerasak Samee, Mingkwan Na Takuathung, Siriporn Okonogi, Sathaporn Nimkulrat, Sirivan Athikomkulchai

“…<i>C. chinense</i> stem extract and nanoparticles decreased mitochondrial membrane potential (MMP) and induced G0/G1 phase arrest in MCF-7 cells. In conclusion, use of <i>C. chinense</i> stem extract and nanoparticles may serve as a potential therapeutic approach for breast cancer, thus warranting further exploration.…”
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Trends in the national early warning score are associated with subsequent mortality – A prospective three-centre observational study with 11,331 general ward patients by Eetu Loisa, Antti Kallonen, Sanna Hoppu, Joonas Tirkkonen

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