A neuroethics framework for the Australian Brain Initiative by Carter, A, Richards, LJ, Apthorp, D, Levy, NL

“…Neuroethics is central to the Australian Brain Initiative's aim to sustain a thriving and responsible neurotechnology industry. …”

Neuroethics questions to guide ethical research in the international brain initiatives by Delegates, G, Rommelfanger, K, Jeong, S, Ema, A, Fukushi, T, Kasai, K, Ramos, K, Salles, A, Singh, I

“…With this Perspective article, we aim to prioritize and advance to the foreground a list of neuroethics questions for neuroscientists operating in the context of these international brain initiatives.…”

The Healthy Brain Initiative (HBI): A prospective cohort study protocol. by Lilah M Besser, Stephanie Chrisphonte, Michael J Kleiman, Deirdre O'Shea, Amie Rosenfeld, Magdalena Tolea, James E Galvin

“…<h4>Background</h4>The Health Brain Initiative (HBI), established by University of Miami's Comprehensive Center for Brain Health (CCBH), follows racially/ethnically diverse older adults without dementia living in South Florida. …”
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A guide to the BRAIN Initiative Cell Census Network data ecosystem by Michael Hawrylycz, Maryann E. Martone, Giorgio A. Ascoli, Jan G. Bjaalie, Hong-Wei Dong, Satrajit S. Ghosh, Jesse Gillis, Ronna Hertzano, David R. Haynor, Patrick R. Hof, Yongsoo Kim, Ed Lein, Yufeng Liu, Jeremy A. Miller, Partha P. Mitra, Eran Mukamel, Lydia Ng, David Osumi-Sutherland, Hanchuan Peng, Patrick L. Ray, Raymond Sanchez, Aviv Regev, Alex Ropelewski, Richard H. Scheuermann, Shawn Zheng Kai Tan, Carol L. Thompson, Timothy Tickle, Hagen Tilgner, Merina Varghese, Brock Wester, Owen White, Hongkui Zeng, Brian Aevermann, David Allemang, Seth Ament, Thomas L. Athey, Cody Baker, Katherine S. Baker, Pamela M. Baker, Anita Bandrowski, Samik Banerjee, Prajal Bishwakarma, Ambrose Carr, Min Chen, Roni Choudhury, Jonah Cool, Heather Creasy, Florence D’Orazi, Kylee Degatano, Benjamin Dichter, Song-Lin Ding, Tim Dolbeare, Joseph R. Ecker, Rongxin Fang, Jean-Christophe Fillion-Robin, Timothy P. Fliss, James Gee, Tom Gillespie, Nathan Gouwens, Guo-Qiang Zhang, Yaroslav O. Halchenko, Nomi L. Harris, Brian R. Herb, Houri Hintiryan, Gregory Hood, Sam Horvath, Bingxing Huo, Dorota Jarecka, Shengdian Jiang, Farzaneh Khajouei, Elizabeth A. Kiernan, Huseyin Kir, Lauren Kruse, Changkyu Lee, Boudewijn Lelieveldt, Yang Li, Hanqing Liu, Lijuan Liu, Anup Markuhar, James Mathews, Kaylee L. Mathews, Chris Mezias, Michael I. Miller, Tyler Mollenkopf, Shoaib Mufti, Christopher J. Mungall, Joshua Orvis, Maja A. Puchades, Lei Qu, Joseph P. Receveur, Bing Ren, Nathan Sjoquist, Brian Staats, Daniel Tward, Cindy T. J. van Velthoven, Quanxin Wang, Fangming Xie, Hua Xu, Zizhen Yao, Zhixi Yun, Yun Renee Zhang, W. Jim Zheng, Brian Zingg

“…This Consensus View provides a guide to the cellular and spatial approaches used in cell type surveys by the BRAIN Initiative Cell Census Network (BICCN), as well as information on accessing and using the BICCN data and its extensive resources.…”
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A guide to the BRAIN Initiative Cell Census Network data ecosystem. by Michael Hawrylycz, Maryann E Martone, Giorgio A Ascoli, Jan G Bjaalie, Hong-Wei Dong, Satrajit S Ghosh, Jesse Gillis, Ronna Hertzano, David R Haynor, Patrick R Hof, Yongsoo Kim, Ed Lein, Yufeng Liu, Jeremy A Miller, Partha P Mitra, Eran Mukamel, Lydia Ng, David Osumi-Sutherland, Hanchuan Peng, Patrick L Ray, Raymond Sanchez, Aviv Regev, Alex Ropelewski, Richard H Scheuermann, Shawn Zheng Kai Tan, Carol L Thompson, Timothy Tickle, Hagen Tilgner, Merina Varghese, Brock Wester, Owen White, Hongkui Zeng, Brian Aevermann, David Allemang, Seth Ament, Thomas L Athey, Cody Baker, Katherine S Baker, Pamela M Baker, Anita Bandrowski, Samik Banerjee, Prajal Bishwakarma, Ambrose Carr, Min Chen, Roni Choudhury, Jonah Cool, Heather Creasy, Florence D'Orazi, Kylee Degatano, Benjamin Dichter, Song-Lin Ding, Tim Dolbeare, Joseph R Ecker, Rongxin Fang, Jean-Christophe Fillion-Robin, Timothy P Fliss, James Gee, Tom Gillespie, Nathan Gouwens, Guo-Qiang Zhang, Yaroslav O Halchenko, Nomi L Harris, Brian R Herb, Houri Hintiryan, Gregory Hood, Sam Horvath, Bingxing Huo, Dorota Jarecka, Shengdian Jiang, Farzaneh Khajouei, Elizabeth A Kiernan, Huseyin Kir, Lauren Kruse, Changkyu Lee, Boudewijn Lelieveldt, Yang Li, Hanqing Liu, Lijuan Liu, Anup Markuhar, James Mathews, Kaylee L Mathews, Chris Mezias, Michael I Miller, Tyler Mollenkopf, Shoaib Mufti, Christopher J Mungall, Joshua Orvis, Maja A Puchades, Lei Qu, Joseph P Receveur, Bing Ren, Nathan Sjoquist, Brian Staats, Daniel Tward, Cindy T J van Velthoven, Quanxin Wang, Fangming Xie, Hua Xu, Zizhen Yao, Zhixi Yun, Yun Renee Zhang, W Jim Zheng, Brian Zingg

“…Classification of neurons is also essential to manipulate cell types in controlled ways and to understand their variation and vulnerability in brain disorders. The BRAIN Initiative Cell Census Network (BICCN) is an integrated network of data-generating centers, data archives, and data standards developers, with the goal of systematic multimodal brain cell type profiling and characterization. …”
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Precision Anaesthesia: Advancing Patient-Centered Precision Care Through Repetitive Assessment of PROMs with the Safe Brain Initiative Approach by Başak Ceyda Meço, Ana Borda de Agua Reis, Joana Berger-Estilita, Karina Jakobsen, Neslihan Alkış, Finn Michael Radtke

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Evolving applications, technological challenges and future opportunities in neuromodulation: Proceedings of the fifth annual deep brain stimulation think tank by Ramirez-Zamora, A, Giordano, JJ, Gunduz, A, Brown, P, Sanchez, JC, Foote, KD, Almeida, L, Starr, PA, Bronte-Stewart, HM, Hu, W, McIntyre, C, Goodman, W, Kumsa, D, Grill, WM, Walker, HC, Johnson, MD, Vitek, JL, Greene, D, Rizzuto, DS, Song, D, Berger, TW, Hampson, RE, Deadwyler, SA, Hochberg, LR, Schiff, ND, Stypulkowski, P, Worrell, G, Tiruvadi, V, Mayberg, HS, Jimenez-Shahed, J, Nanda, P, Sheth, SA, Gross, RE, Lempka, SF, Li, L, Deeb, W, Okun, MS

“…Specifically, this year's meeting focused on technical developments in DBS, design considerations for DBS electrodes, improved sensors, neuronal signal processing, advancements in development and uses of responsive DBS (closed-loop systems), updates on National Institutes of Health and DARPA DBS programs of the BRAIN initiative, and neuroethical and policy issues arising in and from DBS research and applications in practice.…”

Cell-Type Specific Analysis of Selenium-Related Genes in Brain by Alexandru R. Sasuclark, Vedbar S. Khadka, Matthew W. Pitts

“…Due to advances in sequencing technology and investment from the National Institutes of Health (NIH)-sponsored BRAIN initiative, RNA sequencing (RNAseq) data from thousands of cortical neurons can now be freely accessed and searched using the online RNAseq data navigator at the Allen Brain Atlas. …”
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Pre-birth acquisition of personhood: Incremental accrual of attributes as the framework for individualization by serial and concurrently acting developmental factors by Claude L. Hughes, Gavin C. Hughes

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Towards an understanding of global brain data governance: ethical positions that underpin global brain data governance discourse by Paschal Ochang, Damian Eke, Bernd Carsten Stahl, Bernd Carsten Stahl

“…Therefore, this study aims to bridge these gaps by exploring the ethical foundations that underlie contextual stakeholder discussions on brain data governance.MethodIn this study we conducted a secondary analysis of interviews with 21 neuroscientists drafted from the International Brain Initiative (IBI), LATBrain Initiative and the Society of Neuroscientists of Africa (SONA) who are involved in various brain projects globally and employing ethical theories. …”
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NSF workshop report: discovering general principles of nervous system organization by comparing brain maps across species. by Striedter, G, Belgard, G, Chen, C, Davis, F, Finlay, B, Güntürkün, O, Hale, M, Harris, J, Hecht, E, Hof, P, Hofmann, H, Holland, L, Iwaniuk, A, Jarvis, E, Karten, H, Katz, P, Kristan, W, Macagno, E, Mitra, P, Moroz, L, Preuss, T, Ragsdale, C, Sherwood, C, Stevens, C, Stüttgen, M

“…Efforts to understand nervous system structure and function have received new impetus from the federal Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative. Comparative analyses can contribute to this effort by leading to the discovery of general principles of neural circuit design, information processing, and gene-structure-function relationships that are not apparent from studies on single species. …”

NSF workshop report: discovering general principles of nervous system organization by comparing brain maps across species. by Striedter, G, Belgard, G, Chen, C, Davis, F, Finlay, B, Güntürkün, O, Hale, M, Harris, J, Hecht, E, Hof, P, Hofmann, H, Holland, L, Iwaniuk, A, Jarvis, E, Karten, H, Katz, P, Kristan, W, Macagno, E, Mitra, P, Moroz, L, Preuss, T, Ragsdale, C, Sherwood, C, Stevens, C, Stüttgen, M

“…Efforts to understand nervous system structure and function have received new impetus from the federal Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative. Comparative analyses can contribute to this effort by leading to the discovery of general principles of neural circuit design, information processing, and gene-structure-function relationships that are not apparent from studies on single species. …”

STAT3 and NTRK2 Genes Predicted by the Bioinformatics Approach May Play Important Roles in the Pathogenesis of Multiple Sclerosis and Obsessive–Compulsive Disorder by Ali Sepehrinezhad, Ali Shahbazi, Ali Bozorgmehr, Babak Kateb, Vicky Yamamoto, Sajad Sahab Negah

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Public-Private Partnership as Timely Innovation Factor of the USA by A. V. FROLOV

“…Trump, Manufacturing USA  net grows and new international innovation partnerships with US  participation demonstrate growing internation al importance of such  cooperation: BRAIN Initiative declared at the Australian Academy of  Science in Canberra in December 2017 by representatives of the  United States, Australia, Europe, Japan and Korea is declared to  unite USA with major countries of former Trans-Pacific Partnership  Trade Agreement, TPP (Including USA, Australia, Japan, Korea) notwithstanding the fact that D. …”
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A comparison of neuroelectrophysiology databases by Priyanka Subash, Alex Gray, Misque Boswell, Samantha L. Cohen, Rachael Garner, Sana Salehi, Calvary Fisher, Samuel Hobel, Satrajit Ghosh, Yaroslav Halchenko, Benjamin Dichter, Russell A. Poldrack, Chris Markiewicz, Dora Hermes, Arnaud Delorme, Scott Makeig, Brendan Behan, Alana Sparks, Stephen R Arnott, Zhengjia Wang, John Magnotti, Michael S. Beauchamp, Nader Pouratian, Arthur W. Toga, Dominique Duncan

“…This paper compares four freely available intracranial neuroelectrophysiology data repositories: Data Archive for the BRAIN Initiative (DABI), Distributed Archives for Neurophysiology Data Integration (DANDI), OpenNeuro, and Brain-CODE. …”
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Kir4.1 channel activation in NG2 glia contributes to remyelination in ischemic strokeResearch in context by Xiaoqi Hong, Yujin Jian, Shenghao Ding, Jianpo Zhou, Xiaoli Zheng, Huimin Zhang, Butian Zhou, Canbin Zhuang, Jieqing Wan, Xiaoping Tong

“…Funding: This work was supported by grants from the Ministry of Science and Technology China Brain Initiative (2022ZD0204702, to X.T.), the National Natural Science Foundation of China (82271466, 82171279, 31970904 and 31571063), the Program for Professor of Special Appointment (Eastern Scholar for Dr. …”
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Clinical performance of an antibody-free assay for plasma Aβ42/Aβ40 to detect early alterations of Alzheimer’s disease in individuals with subjective cognitive decline by María Pascual-Lucas, José Antonio Allué, Leticia Sarasa, Noelia Fandos, Sergio Castillo, Jose Terencio, Manuel Sarasa, Juan Pablo Tartari, Ángela Sanabria, Lluís Tárraga, Agustín Ruíz, Marta Marquié, Sang Won Seo, Hyemin Jang, Mercè Boada, on behalf of the FACEHBI study group

“…Methods This cohort study included data from the baseline and 2-year follow-up visits from the Fundació ACE Healthy Brain Initiative (FACEHBI) study. Plasma Aβ42/Aβ40 was measured with ABtest-MS and compared to 18F-Florbetaben PET as the reference standard (cutoff for early amyloid deposition of 13.5 centiloids). …”
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Achieving a robust mentoring and research capacity program in a LMIC – the BRAINS faculty development model by Folasade Tolulope Ogunsola, Adekemi Sekoni, Alani Sulaimon Akanmu, Wasiu Lanre Adeyemo, Akinniyi Osuntoki, Bibiane Manga-Atangana, Bosede Bukola Afolabi, Njideka Ulunma Okubadejo, Madonna Emmanuel, Sikeade Olawumi Caleb-Adepoju, Olalekan Folarin, Prosper Okonkwo, Robert L Murphy, Phyllis Kanki

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SPONTANEOUS MIGRATION OF A BULLET ALONG HEMISPHERE: A CASE REPORT by S. Başarslan, Bedi Günenç

“…We report the case of a 45-year-old man with a gunshot injury as an example of spontaneous migration of a metallic foreign body within the brain. Initial computed tomography showed the bullet in the right frontal region. …”
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Tracking the neural codes for words and phrases during semantic composition, working-memory storage, and retrieval by Théo Desbordes, Jean-Rémi King, Stanislas Dehaene

“…In conclusion, we propose that the brain initially encodes phrases using factorized dimensions for successive words but later compresses them in working memory and requires a period of decompression to access them.…”
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