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  1. 401

    Model for bridging the translational "valleys of death" in spinal cord injury research by Barrable B, Thorogood N, Noonan V, Tomkinson J, Joshi P, Stephenson K, Barclay J, Kovacs Burns K

    Published 2014-04-01
    “…Bill Barrable,1 Nancy Thorogood,1 Vanessa Noonan,1,2 Jocelyn Tomkinson,1 Phalgun Joshi,1 Ken Stephenson,1 John Barclay,1 Katharina Kovacs Burns3 1Rick Hansen Institute, 2Division of Spine, Department of Orthopaedics, University of British Columbia, Vancouver, BC, 3Health Sciences Council, University of Alberta, Edmonton, AB, Canada Abstract: To improve health care outcomes with cost-effective treatments and prevention initiatives, basic health research must be translated into clinical application and studied during implementation, a process commonly referred to as translational research. …”
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    Article
  2. 402

    Human cell-adhesion molecule CD2 binds CD58 (LFA-3) with a very low affinity and an extremely fast dissociation rate but does not bind CD48 or CD59. by van der Merwe, P, Barclay, A, Mason, D, Davies, E, Morgan, B, Tone, M, Krishnam, A, Ianelli, C, Davis, S

    Published 1994
    “…H., Davis, S. J., and Barclay, A. N. (1993) EMBO J. 12, 4945-4954]. In contrast, a study using conventional equilibrium binding methods reported a much higher affinity (Kd 0.4 microM) for human CD2 binding CD58 which suggested that the weak binding of rat CD2 to CD48 may not represent a typical CAM interaction. …”
    Journal article
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