P463: RE-PURPOSING OF GENE SIGNATURES IN AML UNCOVERS NOVEL ENERGETICS-ASSOCIATED MOLECULAR SUBTYPES by P. Strain, E. E. Scanlon, G. Jellema, R. D. Kennedy, K. I. Mills, J. K. Blayney

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Effects of Hyperoxia on Pulmonary Inflammation and organ injury in a human in vivo model (HIPI): study protocol of a randomised, double-blind, placebo-controlled trial by Daniel Francis McAuley, David Moore, Judy M Bradley, John Conlon, Clifford C Taggart, Melanie Bailey, Dermot Linden, Delia Dorrian, Shikha Tandel, Michael McKelvey, Sharon Carr, Joseph Kidney, Cecilia M OKane

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A Drug Content, Stability Analysis, and Qualitative Assessment of Pharmacists’ Opinions of Two Exemplar Extemporaneous Formulations by Melissa Kirkby, Kurtis Moffatt, Aoife M. Rogers, Paul J. McCague, James C. McElnay, Caoimhe Quinn, Lezley Ann McCullough, Johanne Barry, Ryan F. Donnelly

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Utility of fractional exhaled nitric oxide suppression as a prediction tool for progression to biologic therapy by Claire A. Butler, Alan J. McMichael, Kirsty Honeyford, Louise Wright, Jayne Logan, Joshua Holmes, John Busby, Catherine E. Hanratty, Freda Yang, Steven J. Smith, Kirsty Murray, Rekha Chaudhuri, Liam G. Heaney

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Study on the Structure-Activity Relationship of an Antimicrobial Peptide, Brevinin-2GUb, from the Skin Secretion of <i>Hylarana guentheri</i> by Yaxian Lin, Siyan Liu, Xinping Xi, Chengbang Ma, Lei Wang, Xiaoling Chen, Zhanzhong Shi, Tianbao Chen, Chris Shaw, Mei Zhou

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Deferasirox Nanosuspension Loaded Dissolving Microneedles for Intradermal Delivery by Hafsa Shahid Faizi, Lalitkumar K. Vora, Muhammad Iqbal Nasiri, Yu Wu, Deepakkumar Mishra, Qonita Kurnia Anjani, Alejandro J. Paredes, Raghu Raj Singh Thakur, Muhammad Usman Minhas, Ryan F. Donnelly

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Exercise prescription improves exercise tolerance in young children with CHD: a randomised clinical trial by Brian Grant, Andrew J Sands, Frank A Casey, Sinead Callaghan, Margaret Louise Morrison, Pascal P McKeown, Christopher Tennyson, Brian McCrossan, Brian G Craig

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Removal of single and dual ring thiophene’s from dodecane using cavitation based processes by Peter Delaney, Varaha P. Sarvothaman, Ronan Colgan, Sanjay Nagarajan, Gunjan Deshmukh, David Rooney, Peter K.J. Robertson, Vivek V. Ranade

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Identification and Rational Design of a Novel Antibacterial Peptide Dermaseptin-AC from the Skin Secretion of the Red-Eyed Tree Frog <i>Agalychnis callidryas</i> by Zijian Gong, Xinjie Pei, Shen Ren, Xiaoling Chen, Lei Wang, Chengbang Ma, Xinping Xi, Tianbao Chen, Chris Shaw, Mei Zhou

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Modification Strategy of D-leucine Residue Addition on a Novel Peptide from <i>Odorrana schmackeri</i>, with Enhanced Bioactivity and In Vivo Efficacy by Aifang Yao, Yingxue Ma, Xiaoling Chen, Mei Zhou, Xinping Xi, Chengbang Ma, Shen Ren, Tianbao Chen, Chris Shaw, Lei Wang

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Analysis of SARS-CoV-2 antibody seroprevalence in Northern Ireland during 2020–2021 by Michelle K. Greene, Peter Smyth, Andrew English, Joseph McLaughlin, Magda Bucholc, Janice Bailie, Julie McCarroll, Margaret McDonnell, Alison Watt, George Barnes, Mark Lynch, Kevan Duffin, Gerard Duffy, Claire Lewis, Jacqueline A. James, Alan W. Stitt, Tom Ford, Maurice O'Kane, Taranjit Singh Rai, Anthony J. Bjourson, Christopher Cardwell, J Stuart Elborn, David S. Gibson, Christopher J. Scott

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ADAM17-Dependent c-MET-STAT3 Signaling Mediates Resistance to MEK Inhibitors in KRAS Mutant Colorectal Cancer by Sandra Van Schaeybroeck, Murugan Kalimutho, Philip D. Dunne, Robbie Carson, Wendy Allen, Puthen V. Jithesh, Keara L. Redmond, Takehiko Sasazuki, Senji Shirasawa, Jaine Blayney, Paolo Michieli, Cathy Fenning, Heinz-Josef Lenz, Mark Lawler, Daniel B. Longley, Patrick G. Johnston

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Assessment of Cold Atmospheric Pressure Plasma (CAPP) Treatment for Degradation of Antibiotic Residues in Water by Ewa Wielogorska, Padrig B. Flynn, Julie Meneely, Thomas P. Thompson, William G. Graham, Brendan F. Gilmore, Christopher T. Elliott

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The Influence of Orthopedic Surgery on Circulating Metabolite Levels, and their Associations with the Incidence of Postoperative Delirium by Mijin Jung, Xiaobei Pan, Emma L. Cunningham, Anthony P. Passmore, Bernadette McGuinness, Daniel F. McAuley, David Beverland, Seamus O’Brien, Tim Mawhinney, Jonathan M. Schott, Henrik Zetterberg, Brian D. Green

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Evaluation of the Antimicrobial Properties of a Natural Peptide from <i>Vespa mandarinia</i> Venom and Its Synthetic Analogues as a Possible Route to Defeat Drug-Resistant Microbes by Jin Zhang, Ruize Sun, Zhiwei Chen, Chunyuan Zhou, Chengbang Ma, Mei Zhou, Xiaoling Chen, Tianbao Chen, Chris Shaw, Lei Wang

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Conjugation of a Cationic Cell-Penetrating Peptide with a Novel Kunitzin-like Trypsin Inhibitor: New Insights for Enhancement of Peptide Bioactivities by Junting Yao, Weining Yin, Yuqing Chen, Xiaoling Chen, Yangyang Jiang, Tao Wang, Chengbang Ma, Mei Zhou, Tianbao Chen, Chris Shaw, Lei Wang

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Potential of Polymeric Films Loaded with Gold Nanorods for Local Hyperthermia Applications by Álvaro Cárcamo-Martínez, Juan Domínguez-Robles, Brónach Mallon, Md. Taifur Raman, Ana Sara Cordeiro, Steven E. J. Bell, Eneko Larrañeta, Ryan F. Donnelly

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Enhanced CO2 capture and reverse water gas shift reaction using CaO in NaCl-CaCl2 molten salt medium by Xiaotong Zhao, Shuzhuang Sun, Yuanyuan Wang, Yingrui Zhang, Yuan Zhu, Bo Zong, Jia Hu, Chunfei Wu

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Cohort profile: DNA methylation in the Northern Ireland Cohort for the Longitudinal Study of Ageing (NICOLA) – recruitment and participant characteristics by Bernadette Mcguinness, Frank Kee, Claire Hill, Claire Potter, Angela Scott, Amy McKnight, Charlotte Neville, Laura J Smyth

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A Novel Kunitzin-Like Trypsin Inhibitor Isolated from Defensive Skin Secretion of <i>Odorrana versabilis</i> by Yanjing Dong, Daning Shi, Yuan Ying, Xinping Xi, Xiaoling Chen, Lei Wang, Mei Zhou, Qinan Wu, Chengbang Ma, Tianbao Chen

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