Exacerbated Neuropathy in POLAR A and M Trials Due to Redox Interaction of PledOx-Associated Mn²⁺ and Oxaliplatin-Associated Pt²⁺ by Jan Olof G. Karlsson, Per Jynge, Louis J. Ignarro

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Prospective evaluation of intense pulsed light and meibomian gland expression efficacy on relieving signs and symptoms of dry eye disease due to meibomian gland dysfunction by Dell SJ, Gaster RN, Barbarino SC, Cunningham DN

“…Steven J Dell,1 Ronald N Gaster,2 Sheila C Barbarino,1 Derek N Cunningham1 1Dell Laser Consultants, Austin, TX, 2Gaster Eye Center, Beverly Hills, CA, USA Purpose: The aim of this study was to estimate the efficacy of intense pulsed light (IPL), followed by meibomian gland expression (MGX), for reducing the number and severity of signs and symptoms of dry eye disease (DED) secondary to meibomian gland dysfunction (MGD). …”
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Cost-effectiveness of the once-daily efavirenz/emtricitabine/tenofovir tablet compared with the once-daily elvitegravir/cobicistat/emtricitabine/tenofovir tablet as first-line anti... by Juday T, Correll T, Anene A, Broder MS, Ortendahl J, Bentley T

“…Timothy Juday,1 Todd Correll,1 Ayanna Anene,2 Michael S Broder,2 Jesse Ortendahl,2 Tanya Bentley21Bristol-Myers Squibb, Plainsboro, NJ, USA; 2Partnership for Health Analytic Research LLC, Beverly Hills, CA, USABackground: February 2013 US treatment guidelines recommend the once-daily tablet of efavirenz/emtricitabine/tenofovir (Atripla®) as a preferred regimen and the once-daily tablet of elvitegravir/cobicistat/emtricitabine/tenofovir (Stribild™) as an alternative regimen for first-line treatment of human immunodeficiency virus (HIV). …”
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May Mangafodipir or Other SOD Mimetics Contribute to Better Care in COVID-19 Patients? by Jan Olof G Karlsson, Per Jynge, Louis J Ignarro

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Using a transdiagnostic, psychodynamic online self-help intervention to maintain inpatient psychosomatic treatment effects: Study protocol of a feasibility study by Jan Becker, Rüdiger Zwerenz, Robert Johansson, Ronald J. Frederick, Gerhard Andersson, Manfred E. Beutel

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Presentation and management of infection in total disc replacement: A review by Hannah Spece, PhD, Armen Khachatryan, MD, Frank M. Phillips, MD, Todd H. Lanman, MD, Gunnar B.J. Andersson, MD, Grant E. Garrigues, MD, Hyun Bae, MD, Joshua J. Jacobs, MD, Steven M. Kurtz, PhD

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Medication Adherence and Healthcare Utilization in Relapsing-Remitting Multiple Sclerosis Patients Using Teriflunomide by Greene N, Higuchi K, Bognar K, Chang E, Broder MS

“…Nupur Greene,1 Keiko Higuchi,1 Katalin Bognar,2 Eunice Chang,2 Michael S Broder2 1Neurology & Immunology (N&I), Sanofi, Cambridge, MA, USA; 2Real World Evidence, PHAR (Partnership for Health Analytic Research), Beverly Hills, CA, USACorrespondence: Nupur Greene, Global HEVA Business Partner, N&I, Sanofi, 450 Water Street, Cambridge, MA, USA, Tel +1 857 259 0037, Email Nupur.Greene@sanofi.comPurpose: Multiple sclerosis (MS) is a costly, immune-mediated disease of the central nervous system. …”
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Differential modulation of cancer‐related genes by mitochondrial DNA haplogroups and the STING DNA sensing system by Kevin Schneider, Marilyn Chwa, Shari R. Atilano, Sonali Nashine, Nitin Udar, David S. Boyer, S. Michal Jazwinski, Michael V. Miceli, Anthony B. Nesburn, Baruch D. Kuppermann, M. Cristina Kenney

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Implementation of an intervention aimed at deprescribing benzodiazepines in a large US healthcare system using patient education materials: a pre/post-observational study with a co... by Ha Hoang, Kristin Bradley, Michelle S Keller, Scott Campbell, Tammy M Le, Alexa Andraos, Pedro Ahlmark, Sean Isserman, Caroline L Goldzweig, Allison M Mays

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Autologous Fat Grafting Restores Soft-tissue Contour Deformities after Vascular Anomaly Surgery by Teresa Minjung O, MD, MArch, FACS, Kimberly Chan, BS, Tara Brennan, MD, Dylan Roden, MD, David Shamouelian, MD, Ho Yun Chung, MD, PhD, Milton Waner, MD

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Facet-sparing lumbar decompression with a minimally invasive flexible MicroBlade Shaver® versus traditional decompression: quantitative radiographic assessment by Lauryssen C, Berven S, Mimran R, Summa C, Sheinberg M, Miller LE, Block JE

“…Carl Lauryssen,1 Sigurd Berven,2 Ronnie Mimran,3 Christopher Summa,4 Michael Sheinberg,5 Larry E Miller,6,7 Jon E Block71Tower Orthopedics, Beverly Hills, CA, USA; 2Department of Orthopedics, University of California, San Francisco, San Francisco, CA, USA; 3Pacific Brain and Spine, Castro Valley, CA, USA; 4The Spine Clinic of Monterey Bay, Soquel, CA, USA; 5Danville, CA, USA; 6Miller Scientific Consulting Inc, Arden, NC, USA; 7The Jon Block Group, San Francisco, CA, USABackground: Laminectomy/laminotomy and foraminotomy are well established surgical techniques for treatment of symptomatic lumbar spinal stenosis. …”
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Diabetes Empowerment Council: Integrative Pilot Intervention for Transitioning Young Adults With Type 1 Diabetes by Marc J Weigensberg MD, Cheryl Vigen PhD, Paola Sequeira MD, Donna Spruijt-Metz MFA, PhD, Magaly Juarez BA, Daniella Florindez MPH, Joseph Provisor MA, LMFT, Anne Peters MD, Elizabeth A Pyatak PhD, OTR/L, CDE

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Association of fruits, vegetables, and fiber intake with COVID-19 severity and symptoms in hospitalized patients: A cross-sectional study by Kiana Tadbir Vajargah, Nikan Zargarzadeh, Armin Ebrahimzadeh, Seyed Mohammad Mousavi, Parnia Mobasheran, Pari Mokhtari, Habib Rahban, Habib Rahban, Mihnea-Alexandru Găman, Mihnea-Alexandru Găman, Camellia Akhgarjand, Mohsen Taghizadeh, Alireza Milajerdi

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Efficacy and Safety of Alirocumab 150 mg Every 4 Weeks in Patients With Hypercholesterolemia Not on Statin Therapy: The ODYSSEY CHOICE II Study by Erik Stroes, John R. Guyton, Norman Lepor, Fernando Civeira, Daniel Gaudet, Gerald F. Watts, Marie T. Baccara‐Dinet, Guillaume Lecorps, Garen Manvelian, Michel Farnier, the ODYSSEY CHOICE II Investigators

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Multiple arterial versus single arterial grafting in patients with diabetes undergoing coronary artery bypass surgeryCentral MessagePerspective by Doaa Alsaleh, MD, Erick Sun, MD, Anas Alzahrani, MD, Shinobu Itagaki, MD, John Puskas, MD, Joanna Chikwe, MD, Natalia Egorova, PhD

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Development of a Severity Classification System for Sickle Cell Disease by Shah N, Beenhouwer D, Broder MS, Bronte-Hall L, De Castro LM, Gibbs SN, Gordeuk VR, Kanter J, Klings ES, Lipato T, Manwani D, Scullin B, Yermilov I, Smith WR

“…Nirmish Shah,1 David Beenhouwer,2 Michael S Broder,2 Lanetta Bronte-Hall,3 Laura M De Castro,4 Sarah N Gibbs,2 Victor R Gordeuk,5 Julie Kanter,6 Elizabeth S Klings,7 Thokozeni Lipato,8 Deepa Manwani,9 Brigid Scullin,10 Irina Yermilov,2 Wally R Smith8 1Department of Medicine, Duke University, Durham, NC, USA; 2Partnership for Health Analytic Research (PHAR), LLC, Beverly Hills, CA, USA; 3Foundation for Sickle Cell Disease Research, Hollywood, FL, USA; 4Department of Medicine, University of Pittsburgh Medical Center, Pittsburgh, PA, USA; 5Department of Medicine, University of Illinois at Chicago, Chicago, IL, USA; 6Department of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA; 7Department of Medicine, Boston University School of Medicine, Boston, MA, USA; 8Department of Internal Medicine, Virginia Commonwealth University, Richmond, VA, USA; 9Department of Pediatrics, Albert Einstein College of Medicine, Bronx, NY, USA; 10Department of Medicine, University of North Carolina, Chapel Hill, NC, USACorrespondence: Nirmish ShahDuke University, Department of Medicine, Duke South, Durham, NC 27710, USATel +1 (919) 668-5178Email nirmish.shah@duke.eduPurpose: There is no well-accepted classification system of overall sickle cell disease (SCD) severity. …”
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Long-term (60-month) results for the implantable miniature telescope: efficacy and safety outcomes stratified by age in patients with end-stage age-related macular degeneration by Boyer D, Freund KB, Regillo C, Levy MH, Garg S

“…David Boyer,1 K Bailey Freund,2 Carl Regillo,3 Marc H Levy,4 Sumit Garg5 1Retina-Vitreous Associates Medical Group, Beverly Hills, CA, 2Vitreous-Retina-Macula Consultants of New York, New York, NY; 3Wills Eye Institute, Philadelphia, PA, 4Sarasota Retina Institute, Sarasota, FL, 5The Gavin Herbert Eye Institute (University of California, Irvine) Irvine, CA, USA Background: The purpose of this study was to evaluate the long-term results of an implantable miniature telescope (IMT) in patients with bilateral, end-stage, age-related macular degeneration (AMD).Methods: A prospective, open-label, multicenter clinical trial with fellow eye controls enrolled 217 patients (mean age 76 years) with AMD and moderate-to-profound bilateral central visual acuity loss (20/80–20/800) resulting from untreatable geographic atrophy, disciform scars, or both. …”
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An Alternative Option for Gender-Affirming Revision Vaginoplasty: The Tubularized Urachus-Peritoneal Hinge Flap by Shannon M. Smith, MD, MPH, Nance Yuan, MD, Jenna Stelmar, BS, Grace Lee PA-C, Amit Gupta, MD, Hyung L. Kim, MD, Maurice M. Garcia, MD, MAS

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One World, Many Cultures / by Hirschberg, Stuart, 1942-, compiler 632933, Hirschberg, Terry, compiler 463852

A Phase I, Single Ascending Dose Study of GEM103 (Recombinant Human Complement Factor H) in Patients with Geographic Atrophy by Arshad M. Khanani, MD, MA, Raj K. Maturi, MD, Nika Bagheri, MD, Benjamin Bakall, MD, PhD, David S. Boyer, MD, Stephen S. Couvillion, MD, Dilsher S. Dhoot, MD, Nancy M. Holekamp, MD, Karim N. Jamal, MD, Dennis M. Marcus, MD, Dante Pieramici, MD, Aamir A. Aziz, BS, Kiran C. Patki, MD, William Z. Bridges, Jr., MD, Samuel B. Barone, MD

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