Geometrical and thermodynamic stability of govaniadine scaffold adducts with dopamine receptor D1 by Ram Lal Swagat Shrestha, Binita Maharjan, Timila Shrestha, Bishnu Prasad Marasini, Jhashanath Adhikari Subin

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The overlap of accessory virulence factors and multidrug resistance among clinical and surveillance Klebsiella pneumoniae isolates from a neonatal intensive care unit in Nepal: a s... by Raj Kumar Shrestha, Dhruba Shrestha, Ajaya Jang Kunwar, Sandeep Thapa, Nipun Shrestha, Bhim Gopal Dhoubhadel, Christopher M. Parry

“…Methods Thirty-eight clinical and nineteen surveillance K. pneumoniae isolates obtained between January 2017 and August 2022 in the NICU of Siddhi Memorial Hospital, Bhaktapur, Nepal were investigated with antimicrobial susceptibility testing, PCR-based detection of β-lactamases and virulence factors, and genetic similarity by ERIC–PCR. …”
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Association of Maternal Plasma Total Cysteine and Growth among Infants in Nepal: A Cohort Study by Nikhil Arora, Tor A. Strand, Ram K. Chandyo, Amany Elshorbagy, Laxman Shrestha, Per M. Ueland, Manjeswori Ulak, Catherine Schwinger

“…The aim of this analysis was to assess whether maternal plasma total cysteine (tCys) concentration is associated with various growth indicators in infants living in peri-urban settings in Bhaktapur, Nepal. We used data from the 561 mothers enrolled in an ongoing randomized controlled trial. …”
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Availability, affordability and access to essential medications for asthma and chronic obstructive pulmonary disease in three low- and middle-income country settings by Trishul Siddharthan, Nicole M. Robertson, Natalie A. Rykiel, Lindsay J. Underhill, Nihaal Rahman, Sujan Kafle, Sakshi Mohan, Roma Padalkar, Sarah McKeown, Oscar Flores-Flores, Shumonta A. Quaderi, Patricia Alupo, Robert Kalyesubula, Bruce Kirenga, Jing Luo, Maria Kathia Cárdenas, Gonzalo Gianella, J. Jaime Miranda, William Checkley, John R. Hurst, Suzanne L. Pollard

“…<h4>Methods</h4> All public and private pharmacies in catchment areas of the Global Excellence in COPD outcomes (GECo) study sites in Bhaktapur, Nepal, Lima, Peru, and Nakaseke, Uganda, were approached in 2017–2019 to assess pricing and availability of medications for the management of asthma and COPD. …”
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Identifying determinants of sustainable water management at the household level through rainwater harvesting systems in Nepal by Anusha Thapa, Ghanashyam Khanal, Sushanta Kumar Mahapatra, Niranjan Devkota, Surendra Mahato, Udaya Raj Paudel

“…The results were drawn by surveying 405 respondents who reside in the Kathmandu Valley: Kathmandu, Lalitpur and Bhaktapur districts.;…”
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Diagnostic performance of GeneXpert MTB/RIF in detecting MTB in smear-negative presumptive TB patients by Raksha Rimal, Dhiraj Shrestha, Susil Pyakurel, Rashmi Poudel, Prasha Shrestha, Kul Raj Rai, Gokarna Raj Ghimire, Ganesh Rai, Shiba Kumar Rai

“…Methods The study was carried out from June to December 2016 in Nepal Tuberculosis Center, Bhaktapur, Nepal. A total of 173 sputum samples were collected and processed by microscopy [Auramine-O staining and Ziehl–Neelsen (ZN) staining], followed by GeneXpert MTB/RIF assay and culture in Lowenstein-Jensen (LJ) medium. …”
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Depression and Suicide attempt during Dementia, and their Clinical Correlation in Elderly Indian Population from LASI Wave I (2017-2018) by Poonam Yadav, Akchhara Panday, Ruksana Miraj Uddin, Maanini Mantena, Farheen Firdous, Bishal Pokharel, Meenakhsi Kinha

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Characteristics and dynamic analysis of the February 2021 long-runout disaster chain triggered by massive rock and ice avalanche at Chamoli, Indian Himalaya by Tiantian Zhang, Yueping Yin, Bin Li, Xiaojie Liu, Meng Wang, Yang Gao, Jiawei Wan, Kaushal Raj Gnyawali

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Availability, affordability and access to essential medications for asthma and chronic obstructive pulmonary disease in three low- and middle-income country settings. by Trishul Siddharthan, Nicole M Robertson, Natalie A Rykiel, Lindsay J Underhill, Nihaal Rahman, Sujan Kafle, Sakshi Mohan, Roma Padalkar, Sarah McKeown, Oscar Flores-Flores, Shumonta A Quaderi, Patricia Alupo, Robert Kalyesubula, Bruce Kirenga, Jing Luo, Maria Kathia Cárdenas, Gonzalo Gianella, J Jaime Miranda, William Checkley, John R Hurst, Suzanne L Pollard

“…<h4>Methods</h4>All public and private pharmacies in catchment areas of the Global Excellence in COPD outcomes (GECo) study sites in Bhaktapur, Nepal, Lima, Peru, and Nakaseke, Uganda, were approached in 2017-2019 to assess pricing and availability of medications for the management of asthma and COPD.…”
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Evaluating Retinal Disease Diagnosis with an Interpretable Lightweight CNN Model Resistant to Adversarial Attacks by Mohan Bhandari, Tej Bahadur Shahi, Arjun Neupane

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Common foods for boosting human immunity: A review by Deo Narayan Singh, Jitendra Singh Bohra, Tej Pratap Dubey, Pushp Raj Shivahre, Ram Kumar Singh, Tejbal Singh, Deepak Kumar Jaiswal

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Risk factors for wasting among hospitalised children in Nepal by Aiko Inoue, Bhim Gopal Dhoubhadel, Dhruba Shrestha, Ganendra Bhakta Raya, Yumiko Hayashi, Sudeep Shrestha, Tansy Edwards, Christopher Martin Parry, Koya Ariyoshi, Sharon Elizabeth Cox

“…Methods We enrolled 426 children, aged between 6 months and 15 years, admitted to Siddhi Memorial Hospital, Bhaktapur, Nepal, from November 2016 to June 2017. …”
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Mean Brixia Severity Scores among Symptomatic COVID-19 Patients in a Tertiary Care Centre: A Descriptive Cross-sectional Study by Amit Shrestha, Subodh Shrestha, Abhushan Siddhi Tuladhar, Rumita Kayastha, Roja Khanal, Ashlesha Chaudhary, Anish Bhattarai, Sneha Bimali

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Feasibility of monitoring Global Breast Cancer Initiative Framework key performance indicators in 21 Asian National Cancer Centers Alliance member countriesResearch in context by Sok King Ong, Rei Haruyama, Cheng Har Yip, Tran Thu Ngan, Jingmei Li, Daphne Lai, Yawei Zhang, Siyan Yi, Abhishek Shankar, Evlina Suzanna, So-Youn Jung, Peh Joo Ho, Aasim Yusuf, Ashrafun Nessa, Kyu-Won Jung, Eshani Fernando, Shweta Baral, Maryam Bagherian, Prabhat Pradhan, Uranbolor Jugder, Champadeng Vongdala, Siti Norbayah Yusof, Khin Thiri, Patumrat Sripan, Clarito Cairo, Tomohiro Matsuda, Suleeporn Sangrajran, Veronique Kiak-Mien Tan, Ravi Mehrotra, Benjamin O. Anderson

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Community-Based Cervical Cancer Screening using Visual Inspection with Acetic Acid by Rashmi Mulmi, Gambhir Shrestha, Ayodhya Pathak, Manju Sharma, Tara Dawadi, Bhola Siwakoti, Kishore Kumar Pradhananga

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Multimodal multiscale characterization of cascading hazard on mountain terrain by Rocky Talchabhadel, Shreedhar Maskey, Manish R. Gouli, Kshitij Dahal, Amrit Thapa, Sanjib Sharma, Amod M. Dixit, Saurav Kumar

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Chemical Composition, Enantiomeric Distribution, Antimicrobial and Antioxidant Activities of <i>Origanum majorana</i> L. Essential Oil from Nepal by Prem Narayan Paudel, Prabodh Satyal, Rakesh Satyal, William N. Setzer, Rajendra Gyawali

“…GC-MS analysis showed the presence of 50 and 41 compounds in the EO samples, (S₁) and (S₂), respectively, representing the Kathmandu and Bhaktapur districts. The oxygenated monoterpenoids, along with terpinen-4-ol, were predominant constituents in both EO samples. …”
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Effective biosorption of As(V) from polluted water using Fe(III)-modified Pomelo (Citrus maxima) peel: A batch, column, and thermodynamic study by Deepak Gyawali, Sangita Rijal, Prabin Basnet, Kedar Nath Ghimire, Megh Raj Pokhrel, Hari Paudyal

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Correlation of Body Mass Index and Oxygen Saturation in Chronic Obstructive Pulmonary Disease Patients at a Tertiary Care Center in Nepal: A Cross-Sectional Study by Sangroula P, Ghimire S, Srivastava B, Adhikari D, Dhonju K, Shrestha A, Ghimire S

“…Prativa Sangroula,1,&ast; Sandip Ghimire,1,&ast; Brajendra Srivastava,2 Divas Adhikari,3 Kiran Dhonju,4 Amit Shrestha,5 Sapana Ghimire6 1Department of Internal Medicine, Lumbini Medical College and Teaching Hospital, Palpa, Lumbini, Nepal; 2Department of Internal Medicine, Nepalese Army Institute of Health Sciences, Kathmandu, Bagmati, Nepal; 3Department of Emergency Medicine, Bharatpur Hospital, Chitwan, Bagmati, Nepal; 4Department of Internal Medicine, Sukraraj Tropical and Infectious Disease Hospital, Kathmandu, Bagmati, Nepal; 5Department of Psychiatry, Patan Academy of Health Sciences, Lalitpur, Bagmati, Nepal; 6Department of Pathology, Shahid Dharma Bhakta National Transplant Centre, Bhaktapur, Bagmati, Nepal&ast;These authors contributed equally to this workCorrespondence: Sandip Ghimire, Department of Internal Medicine, Lumbini Medical College and Teaching Hospital, Palpa, Lumbini, Nepal, Tel +9609369402 ; +9779851119799, Email docsandipghimire@gmail.comPurpose: Chronic obstructive pulmonary disease (COPD) is a major cause of mortality and morbidity worldwide. …”
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Performance of the heart failure risk scores in predicting 1 year mortality and short‐term readmission of patients by Xiangwei Bo, Yahao Zhang, Yang Liu, Naresh Kharbuja, Lijuan Chen

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