Implementing Joint External Evaluations of the International Health Regulations (2005) capacities in all countries in the WHO African region: process challenges, lessons learnt and... by Ali Ahmed Yahaya, Miriam Nanyunja, Charles Njuguna, Ambrose Talisuna, Mary Stephen, Antonio Oke, Allan Mpairwe, Amadou Bailo Diallo, Daniel Yota, Roland Kimbi Wango, Zabulon Yoti, Janneth Mghamba, Ibrahima-Soce Fall, Belinda Louise Herring, Christian Massidi, Dick Chamla, Anderson Latt, Viviane Fossouo Ndoungue, Sally-Ann Ohene, Georges Alfred Kizerbo

“…Key challenges were: inadequate understanding of the process by in-country counterparts; competing country priorities; limited time for validating subnational capacities; insufficient availability of SMEs for biosafety and biosecurity, antimicrobial resistance, points of entry, chemical events and radio-nuclear emergencies; and inadequate financing to fill gaps identified. …”
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Horizontal Plasmid Transfer Promotes the Dissemination of Asian Acute Hepatopancreatic Necrosis Disease and Provides a Novel Mechanism for Genetic Exchange and Environmental Adapta... by Songzhe Fu, Dawei Wei, Qian Yang, Guosi Xie, Bo Pang, Yongjie Wang, Ruiting Lan, Qingyao Wang, Xuan Dong, Xiaojun Zhang, Jie Huang, Jie Feng, Ying Liu

“…This study improves our understanding of the global dissemination of the AHPND-associated plasmid and highlights the urgent need to improve biosecurity for shrimp farming. Author Video: An author video summary of this article is available.…”
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Cerebrospinal Fluid Neurofilament Light Predicts Risk of Dementia Onset in Cognitively Healthy Individuals and Rate of Cognitive Decline in Mild Cognitive Impairment: A Prospective... by Kunal Dhiman, Victor L. Villemagne, Christopher Fowler, Pierrick Bourgeat, Qiao-Xin Li, Steven Collins, Ashley I. Bush, Christopher C. Rowe, Colin L. Masters, David Ames, Kaj Blennow, Henrik Zetterberg, Ralph N. Martins, Veer Gupta

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Inactivation of marine bivalve parasites using UV-C irradiation: Examples of Perkinsus olseni and Bonamia ostreae by Sergio Fernández-Boo, Clément Provot, Cyrielle Lecadet, Christophe Stavrakakis, Mathias Papin, Bruno Chollet, Jean-François Auvray, Isabelle Arzul

“…Their control relies on biosecurity measures to prevent their introduction and limit their spread. …”
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Removal of a Subset of Non-essential Genes Fully Attenuates a Highly Virulent Mycoplasma Strain by Joerg Jores, Joerg Jores, Li Ma, Paul Ssajjakambwe, Paul Ssajjakambwe, Elise Schieck, Anne Liljander, Suchismita Chandran, Michael H. Stoffel, Valentina Cippa, Yonathan Arfi, Yonathan Arfi, Nacyra Assad-Garcia, Laurent Falquet, Pascal Sirand-Pugnet, Pascal Sirand-Pugnet, Alain Blanchard, Alain Blanchard, Carole Lartigue, Carole Lartigue, Horst Posthaus, Fabien Labroussaa, Sanjay Vashee

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Epidemiology of Aujeszky's Disease in Pigs in Malaysia by Gurcharan Singh, Jasbir Singh

“…In addition, an effective vaccination programme and a better biosecurity management system in the farms may be necessary to reduce the prevalence of the disease to a point where an eradication programme against AD could be initiated in Malaysia. …”
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Detection and molecular characterization of mycoplasma gallisepticum and mycoplasma synoviae from commercial chickens in Malaysia by Ahmad, Kartini

“…These indices indicate that MG and MS are still persisting in commercial poultry production under current biosecurity and disease control programme. The analysis of multigene families of 20 MG field isolates on six cytadhesin genes revealed their G+C content within 27% - 50% and showed 91-100% sequence homology with MG isolates from USA, Israel, Australia and Russia. …”
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ANGPTL2 binds MAG to efficiently enhance oligodendrocyte differentiation by Lu Chen, Zhuo Yu, Li Xie, Xiaoxiao He, Xingmei Mu, Chiqi Chen, Wenqian Yang, Xiaoping Tong, Junling Liu, Zhengliang Gao, Suya Sun, NanJie Xu, Zhigang Lu, Junke Zheng, Yaping Zhang

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High prevalence of Rickettsia spp. in ticks from wild hedgehogs rather than domestic bovine in Jiangsu province, Eastern China by Yong Qi, Yong Qi, Lele Ai, Lele Ai, Jun Jiao, Junhu Wang, Junhu Wang, Deping Wu, Pengcheng Wang, Guoyu Zhang, Yong Qin, Cheng Hu, Ruichen Lv, Ruichen Lv, Nianhong Lu, Nianhong Lu, Changqiang Zhu, Changqiang Zhu, Yingqing Mao, Yingqing Mao, Rui Qi, Yuexi Li, Yuexi Li, Weilong Tan, Weilong Tan

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Integrating Genetic and Genomic Analyses of Combined Health Data Across Ecotypes to Improve Disease Resistance in Indigenous African Chickens by Georgios Banos, Georgios Banos, Georgios Banos, Victoria Lindsay, Takele T. Desta, Judy Bettridge, Judy Bettridge, Judy Bettridge, Enrique Sanchez-Molano, Adriana Vallejo-Trujillo, Oswald Matika, Tadelle Dessie, Paul Wigley, Robert M. Christley, Peter Kaiser, Olivier Hanotte, Olivier Hanotte, Olivier Hanotte, Androniki Psifidi, Androniki Psifidi, Androniki Psifidi

“…The majority of chickens in sub-Saharan Africa are indigenous, raised in villages under semi-scavenging conditions. Vaccinations and biosecurity measures rarely apply, and infectious diseases remain a major cause of mortality and reduced productivity. …”
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Determinants of Knowledge, Attitude, and Practices of Veterinary Drug Dispensers toward Antimicrobial Use and Resistance in Main Cities of Malawi: A Concern on Antibiotic Stewardsh... by Henson Kainga, Marvin Collen Phonera, Ibrahim Chikowe, Elisha Chatanga, Hlupikire Nyirongo, Mike Luwe, James Mponela, Vincent Kachisi, Nathani Kamanga, Julius Chulu, Gilson Njunga, Daisy Nabadda, Alyce Fonchin, Simegnew Adugna Kallu, Steward Mudenda, Rabecca Tembo, Mildred Zulu, Florence Mwaba, Natalia Mbewe, Prudence Mpundu, Mulemba Tillika Samutela, Musso Munyeme, John Bwalya Muma, Edgar Simulundu

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Screening the Medicines for Malaria Venture Pathogen Box against piroplasm parasites by Arifin Budiman Nugraha, Bumduuren Tuvshintulga, Azirwan Guswanto, Dickson Stuart Tayebwa, Mohamed Abdo Rizk, Sambuu Gantuya, Gaber El-Saber Batiha, Amany Magdy Beshbishy, Thillaiampalam Sivakumar, Naoaki Yokoyama, Ikuo Igarashi

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Metagenomic association analysis of cognitive impairment in community-dwelling older adults by Jincheng Li, Sibo Zhu, Yingzhe Wang, Min Fan, Jiacheng Dai, Chengkai Zhu, Kelin Xu, Mei Cui, Chen Suo, Li Jin, Yanfeng Jiang, Xingdong Chen

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Co-circulation and persistence of multiple A/H3N2 influenza variants in China by Weifeng Shi, Changwen Ke, Shisong Fang, Juan Li, Hao Song, Xiyan Li, Tao Hu, Jie Wu, Tao Chen, Lina Yi, Yingchao Song, Xin Wang, Weijia Xing, Weijuan Huang, Hong Xiao, Lijun Liang, Bo Peng, Weihua Wu, Hui Liu, William J. Liu, Edward C. Holmes, George F. Gao, Dayan Wang

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Neutralization Sensitivity of HIV-1 CRF07_BC From an Untreated Patient With a Focus on Evolution Over Time by Lijie Wang, Shujia Liang, Jianhua Huang, Yibo Ding, Lin He, Yanling Hao, Li Ren, Meiling Zhu, Yi Feng, Abdur Rashid, Yue Liu, Shibo Jiang, Kunxue Hong, Liying Ma

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Epidemiologic and economic considerations regarding persistently infected cattle during vaccinate-to-live strategies for control of foot-and-mouth disease in FMD-free regions by Shankar Yadav, Shankar Yadav, Shankar Yadav, Amy H. Delgado, Amy D. Hagerman, Miranda R. Bertram, Miranda R. Bertram, Karla I. Moreno-Torres, Karla I. Moreno-Torres, Karla I. Moreno-Torres, Carolina Stenfeldt, Carolina Stenfeldt, Lindsey Holmstrom, Jonathan Arzt

“…We developed and simulated scenarios of FMD spread and control in the US livestock population, which included depopulation for a limited period, followed by a vaccinate-to-live strategy with strong biosecurity and movement restrictions. Six scenarios of FMD spread and control were simulated in the InterSpread Plus (ISP) modeling tool. …”
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Identification of Candidate Therapeutic Genes for More Precise Treatment of Esophageal Squamous Cell Carcinoma and Adenocarcinoma by Aneta Polewko-Klim, Sibo Zhu, Sibo Zhu, Sibo Zhu, Weicheng Wu, Weicheng Wu, Yijing Xie, Yijing Xie, Ning Cai, Ning Cai, Kexun Zhang, Kexun Zhang, Zhen Zhu, Zhen Zhu, Tao Qing, Ziyu Yuan, Kelin Xu, Kelin Xu, Tiejun Zhang, Tiejun Zhang, Ming Lu, Ming Lu, Weimin Ye, Weimin Ye, Xingdong Chen, Xingdong Chen, Chen Suo, Chen Suo, Chen Suo, Witold R. Rudnicki, Witold R. Rudnicki

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Leveraging gains from African Center for Integrated Laboratory Training to combat HIV epidemic in sub-Saharan Africa by Ritu Shrivastava, Richard Poxon, Erin Rottinghaus, Leyya Essop, Victoria Sanon, Zawadi Chipeta, Elsie van-Schalkwyk, Phuti Sekwadi, Pelagia Murangandi, Shon Nguyen, Josh Devos, Shanna Nesby-Odell, Thomas Stevens, Farouk Umaru, Alex Cox, Andrea Kim, Chunfu Yang, Linda M. Parsons, Babatyi Malope-Kgokong, John N. Nkengasong

“…Diagnostics courses included Viral Load, and systems strengthening included strategic planning and Biosafety and Biosecurity. SAS v9.44 and Excel were used to analyze retrospective de-identified data collected at six months pre and post-training. …”
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The Host Restriction Factor Interferon-Inducible Transmembrane Protein 3 Inhibits Vaccinia Virus Infection by Chang Li, Chang Li, Chang Li, Chang Li, Shouwen Du, Shouwen Du, Mingyao Tian, Yuhang Wang, Jieying Bai, Peng Tan, Wei Liu, Ronglan Yin, Maopeng Wang, Ying Jiang, Yi Li, Na Zhu, Yilong Zhu, Tiyuan Li, Shipin Wu, Ningyi Jin, Ningyi Jin, Ningyi Jin, Fuchu He

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The Genome of the Acid Soil-Adapted Strain Rhizobium favelukesii OR191 Encodes Determinants for Effective Symbiotic Interaction With Both an Inverted Repeat Lacking Clade and a Pha... by Bertrand Eardly, Wan Adnawani Meor Osman, Julie Ardley, Jaco Zandberg, Margaret Gollagher, Margaret Gollagher, Peter van Berkum, Patrick Elia, Dora Marinova, Rekha Seshadri, T. B. K. Reddy, Natalia Ivanova, Amrita Pati, Tanja Woyke, Nikos Kyrpides, Matthys Loedolff, Damian W. Laird, Wayne Reeve

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