Water taste and odor (T&O): Challenges, gaps and solutions from a perspective of the WaterTOP network by Reyhan Akcaalan, Ricard Devesa-Garriga, Andrea Dietrich, Martin Steinhaus, Andreas Dunkel, Veronika Mall, Maura Manganelli, Simona Scardala, Emanuela Testai, Geoffrey A. Codd, Frantisek Kozisek, Maria Antonopoulou, Ana Rita Lado Ribeiro, Maria José Sampaio, Anastasia Hiskia, Theodoros M. Triantis, Dionysios D. Dionysiou, Gianluca Li Puma, Linda Lawton, Christine Edwards, Henrik Rasmus Andersen, Despo Fatta-Kassinos, Popi Karaolia, Audrey Combès, Kristel Panksep, Sevasti-Kiriaki Zervou, Meriç Albay, Latife Köker, Ekaterina Chernova, Sofia Iliakopoulou, Elisabeth Varga, Petra M. Visser, Angelika Ioanna Gialleli, Zuhal Zengin, Nikos Deftereos, Phani Miskaki, Christophoros Christophoridis, Aikaterina Paraskevopoulou, Tsair-Fuh Lin, Arash Zamyadi, Galina Dimova, Triantafyllos Kaloudis

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Correlates and impacts of human-mammal conflict in the central part of Chitwan Annapurna Landscape, Nepal by Jagan Nath Adhikari, Bishnu Prasad Bhattarai, Tej Bahadur Thapa

“…The chital was the most abundant mammal (encounter rate (ER) = 1.49 and relative abundance (RA) = 55.45%) in block A whereas muntjac had the highest encounter rate in blocks B, C and D (ER = 0.34, 0.31, 0.79 respectively) but the relative abundance of rhesus was comparatively higher in blocks B, C and D. …”
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New treatment for non-Hodgkin B-cell lymphomas with a special focus on the impact of junctional adhesion molecules by Beat A. Imhof, Thomas Matthes

“…One such target is JAM-C, a molecule implicated in cell adhesion and in B cell migration and whose inhibition blocks B cells from reaching their supportive microenvironments in lymphoid organs. …”
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Dual Role of B Cells in Multiple Sclerosis by Gaurav Kumar, Robert C. Axtell

“…Yet, atacicept treatment, which blocks B-cell Activating Factor (BAFF) and A Proliferation-Inducing Ligand (APRIL), two cytokines important for B cell development and function, paradoxically increases disease activity in MS patients. …”
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Bispecific Antibodies: A Smart Arsenal for Cancer Immunotherapies by Gihoon You, Jonghwa Won, Yangsoon Lee, Dain Moon, Yunji Park, Sang Hoon Lee, Seung-Woo Lee

“…Following the clinical success of cancer immunotherapies such as immune checkpoint inhibitors blocking B7/CTLA-4 or PD-1/PD-L1 signaling and ongoing numerous combination therapies in the clinic,3 bispecific antibodies (BsAbs) are now emerging as a growing class of immunotherapies with the potential to improve clinical efficacy and safety further. …”
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Theoretical study : analysis of automated flow lines using discrete-event simulation by Ali, Nor Azizah

“…The key parameters chosen are cycle time (T,), frequency of line stop per cycle (F), actual production time (T,), average hourly production rate (R,), average blocked (B,,), total hours of downtime (D), and line efficiency (E). …”
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Influence of Oligopeptide Length and Distribution on Polyisoprene Properties by Chang-Cheng Wang, Rong Zhang, Shiqi Li, Guangsu Huang, Maozhu Tang, Yun-Xiang Xu

“…In detail, a series of peptide-functionalized polyisoprenes with terminal blocks (B-2A-PIP, B-3A-PIP) or random sequences (R-2A-PIP, R-3A-PIP) are fabricated by using dipeptides (2A) or tripeptides (3A) as crosslinkers to explore the mechanism of terminal interaction on mechanism properties and chain dynamics. …”
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Protein requirement for Trichogaster lalius, blue variety by Jener Alexandre Sampaio Zuanon, Antonio Policarpo Souza Carneiro, Lidiane da Silva Nascimento, Donizete Aparecido da Silva, Marcelo Duarte Pontes, Márcio Yoshiyuki Kanashiro, Ana Lúcia Salaro

“…The experimental design was of randomised blocks (B1 = initial weight of 1.04±0.05 g and B2 = 1.36±0.02 g), with two replicates within each block and five treatments (230, 270, 310, 350 and 390 g CP/kg diet). …”
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Antioxidant, Anti-Inflammatory, Antimicrobial, and Anticancer Activities of Pomegranate Juice Concentrate by Hosam M. Habib, Hamada El-Gendi, Esmail M. El-Fakharany, Mohamed G. El-Ziney, Ahmed F. El-Yazbi, Fatima T. Al Meqbaali, Wissam H. Ibrahim

“…Additionally, PJC demonstrated potent antibacterial effects against human pathogens such as <i>Streptococcus mutans</i> and <i>Aeromonas hydrophila</i> and dose-dependently reduced the proliferation of colorectal, breast, and hepatic cancer cells via apoptosis. Furthermore, PJC blocked B-cell lymphoma 2 (BCl-2) and the expression of a potent cyclin-dependent kinase inhibitor (P21) and enhanced tumor protein (P53) expression, compared to both untreated cells and cells treated with fluoropyrimidine 5-fluorouracil (5-FU). …”
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In Situ Supramolecular Gel Formed by Cyclohexane Diamine with Aldehyde Derivative by Jae-Hyeon Park, Min-Hye Kim, Moo-Lyong Seo, Ji-Ha Lee, Jong-Hwa Jung

“…A mixture of building blocks <b>1</b> and <b>2</b> in various organic solvents, dichloromethane, tetrahydrofuran, chloroform, toluene, and 1,4-dioxane, resulted in the stable formation of supramolecular gel at room temperature within 60–100 s. …”
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B cells targeting therapy in the management of systemic lupus erythematosus by Wen Shi Lee, Olga Amengual

“…Several biologics that modulate B cells, either depleting B cells or blocking B cell functions, have been developed and evaluated in clinical trials. …”
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Laparoscopic Surgery: A Systematic Review of Loop and Knot Security, Varying with the Suture and Sequences, Throws, Rotation and Destabilization of Half-Knots or Half-Hitches by Philippe R. Koninckx, Anastasia Ussia, Arnaud Wattiez, William Kondo, Armando Romeo

“…Surgical knots are sequences of half-knots (H) or half-hitches (S), defined by their number of throws, by an opposite or similar rotation compared with the previous one, and for half-hitches whether they are sliding (s) or blocking (b). Opposite rotation results in (more secure) symmetric (s) knots, similar rotation in asymmetric (a) knots, and changing the active and passive ends has the same effect as changing the rotation. …”
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Contextual Interference Effect Is Independent of Retroactive Inhibition but Variable Practice Is Not Always Beneficial by Benjamin Thürer, Benjamin Thürer, Sarah Gedemer, Anne Focke, Thorsten Stein

“…Subjects practiced the force fields in either a Blocked (B), Random (R), or Constant (C) schedule. In addition, subjects of the Blocked group performed either a retest schedule that did (Blocked-Matched; BM) or did not (Blocked-Unmatched; BU) control for retroactive inhibition. …”
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Paeonol oxime inhibits bFGF-induced angiogenesis and reduces VEGF levels in fibrosarcoma cells. by Hyo-Jeong Lee, Seung-Ae Kim, Hyo-Jung Lee, Soo-Jin Jeong, Ihn Han, Ji Hoon Jung, Eun-Ok Lee, Shudong Zhu, Chang-Yan Chen, Sung-Hoon Kim

“…The treatment with PO blocked bFGF-stimulated migration and in vitro capillary differentiation (tube formation) in a dose-dependent manner. …”
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Nematode Assemblages Development Twenty-One Years after the Introduction of Meadow Soil into Bare Post Mining Spoil Heap by Petra Benetková, Ladislav Háněl, Jan Frouz

“…The soil samples were taken at the beginning of the experiment (1997) and then, after 19 years (2016), were transported into blocks (B) in their surroundings in a 2 m distance (I) and, finally, 30 m from the transported blocks as a control (C), to compare and assess the complexity of soil food web. …”
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Uptake of Biotinylated Spermine in Astrocytes: Effect of Cx43 siRNA, HIV-Tat Protein and Polyamine Transport Inhibitor on Polyamine Uptake by Christian J. Malpica-Nieves, Yomarie Rivera, David E. Rivera-Aponte, Otto Phanstiel, Rüdiger W. Veh, Misty J. Eaton, Serguei N. Skatchkov

“…Using a novel polyamine transport inhibitor (PTI), trimer 44NMe, we blocked b-SPM uptake, showing that PA uptake is via a PTI-sensitive transport mechanism such as organic cation transporter. …”
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Structural Motifs in Aryl Organogermanium Ge-O Derivatives for Material Design by Kirill V. Zaitsev, Igor S. Makarov, Yuri F. Oprunenko, Victor A. Tafeenko, Elmira Kh. Lermontova, Andrei V. Churakov

“…The structural types of these compounds were considered, providing 11 blocks (<b>A</b>–<b>K</b>). The molecular structures of the novel compounds [(<i>p</i>-FC₆H₄)₃Ge]₂O (<b>1</b>), [(<i>p</i>-F₃CC₆H₄)₃Ge]₂O (<b>2</b>), and <i>cyclo</i>-[(<i>p</i>-F₃CC₆H₄)₂GeO]₄ (<b>3</b>) were studied through XRD (X-ray diffraction) analysis. …”
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A Versatile Brij-Linker for One-Step Preparation of Targeted Nanoparticles by Maria Anzengruber, Lisa Marie Nepustil, Fatlinda Kurtaj, Ammar Tahir, Katharina Skoll, Haider Sami, Michael Wirth, Franz Gabor

“…Moreover, the targeting ligand density and thus the cell association of the nanoparticles is easily fine-tuned by selection of the initial ratio of the building blocks. <b>Conclusions</b>: This strategy might be a first step towards the one-step preparation of nanoparticles with tailored functionalities. …”
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Novel Targeted Therapies for Rheumatoid Arthritis Based on Intracellular Signalling and Immunometabolic Changes: A Narrative Review by Marveh Rahmati, Maria Paula Kwesiga, Jiachen Lou, Ai Lyn Tan, Michael F McDermott

“…For example, rituximab therapy blocks B cell activation and abatacept effectively blocks T cell activation in patients with RA. …”
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Synthesis and Anti-Inflammatory Evaluation of a Library of Chiral Derivatives of Xanthones Conjugated with Proteinogenic Amino Acids by Sara F. Vieira, Joana Araújo, Virgínia M. F. Gonçalves, Carla Fernandes, Madalena Pinto, Helena Ferreira, Nuno M. Neves, Maria Elizabeth Tiritan

“…Herein, the synthesis of a library of CDXs is described, by coupling a carboxyxanthone (<b>1</b>) with both enantiomers of proteinogenic amino esters as chiral building blocks (<b>2</b>–<b>31</b>), following the chiral pool strategy. …”
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