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141
Water taste and odor (T&O): Challenges, gaps and solutions from a perspective of the WaterTOP network
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142
Correlates and impacts of human-mammal conflict in the central part of Chitwan Annapurna Landscape, Nepal
Published 2024-02-01“…The chital was the most abundant mammal (encounter rate (ER) = 1.49 and relative abundance (RA) = 55.45%) in block A whereas muntjac had the highest encounter rate in blocks B, C and D (ER = 0.34, 0.31, 0.79 respectively) but the relative abundance of rhesus was comparatively higher in blocks B, C and D. …”
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143
New treatment for non-Hodgkin B-cell lymphomas with a special focus on the impact of junctional adhesion molecules
Published 2017-09-01“…One such target is JAM-C, a molecule implicated in cell adhesion and in B cell migration and whose inhibition blocks B cells from reaching their supportive microenvironments in lymphoid organs. …”
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144
Dual Role of B Cells in Multiple Sclerosis
Published 2023-01-01“…Yet, atacicept treatment, which blocks B-cell Activating Factor (BAFF) and A Proliferation-Inducing Ligand (APRIL), two cytokines important for B cell development and function, paradoxically increases disease activity in MS patients. …”
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145
Bispecific Antibodies: A Smart Arsenal for Cancer Immunotherapies
Published 2021-07-01“…Following the clinical success of cancer immunotherapies such as immune checkpoint inhibitors blocking B7/CTLA-4 or PD-1/PD-L1 signaling and ongoing numerous combination therapies in the clinic,3 bispecific antibodies (BsAbs) are now emerging as a growing class of immunotherapies with the potential to improve clinical efficacy and safety further. …”
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146
Theoretical study : analysis of automated flow lines using discrete-event simulation
Published 2003“…The key parameters chosen are cycle time (T,), frequency of line stop per cycle (F), actual production time (T,), average hourly production rate (R,), average blocked (B,,), total hours of downtime (D), and line efficiency (E). …”
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147
Influence of Oligopeptide Length and Distribution on Polyisoprene Properties
Published 2021-12-01“…In detail, a series of peptide-functionalized polyisoprenes with terminal blocks (B-2A-PIP, B-3A-PIP) or random sequences (R-2A-PIP, R-3A-PIP) are fabricated by using dipeptides (2A) or tripeptides (3A) as crosslinkers to explore the mechanism of terminal interaction on mechanism properties and chain dynamics. …”
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148
Protein requirement for Trichogaster lalius, blue variety
Published 2013-02-01“…The experimental design was of randomised blocks (B1 = initial weight of 1.04±0.05 g and B2 = 1.36±0.02 g), with two replicates within each block and five treatments (230, 270, 310, 350 and 390 g CP/kg diet). …”
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149
Antioxidant, Anti-Inflammatory, Antimicrobial, and Anticancer Activities of Pomegranate Juice Concentrate
Published 2023-06-01“…Additionally, PJC demonstrated potent antibacterial effects against human pathogens such as <i>Streptococcus mutans</i> and <i>Aeromonas hydrophila</i> and dose-dependently reduced the proliferation of colorectal, breast, and hepatic cancer cells via apoptosis. Furthermore, PJC blocked B-cell lymphoma 2 (BCl-2) and the expression of a potent cyclin-dependent kinase inhibitor (P21) and enhanced tumor protein (P53) expression, compared to both untreated cells and cells treated with fluoropyrimidine 5-fluorouracil (5-FU). …”
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150
In Situ Supramolecular Gel Formed by Cyclohexane Diamine with Aldehyde Derivative
Published 2022-01-01“…A mixture of building blocks <b>1</b> and <b>2</b> in various organic solvents, dichloromethane, tetrahydrofuran, chloroform, toluene, and 1,4-dioxane, resulted in the stable formation of supramolecular gel at room temperature within 60–100 s. …”
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151
B cells targeting therapy in the management of systemic lupus erythematosus
Published 2020-01-01“…Several biologics that modulate B cells, either depleting B cells or blocking B cell functions, have been developed and evaluated in clinical trials. …”
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152
Laparoscopic Surgery: A Systematic Review of Loop and Knot Security, Varying with the Suture and Sequences, Throws, Rotation and Destabilization of Half-Knots or Half-Hitches
Published 2023-09-01“…Surgical knots are sequences of half-knots (H) or half-hitches (S), defined by their number of throws, by an opposite or similar rotation compared with the previous one, and for half-hitches whether they are sliding (s) or blocking (b). Opposite rotation results in (more secure) symmetric (s) knots, similar rotation in asymmetric (a) knots, and changing the active and passive ends has the same effect as changing the rotation. …”
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153
Contextual Interference Effect Is Independent of Retroactive Inhibition but Variable Practice Is Not Always Beneficial
Published 2019-05-01“…Subjects practiced the force fields in either a Blocked (B), Random (R), or Constant (C) schedule. In addition, subjects of the Blocked group performed either a retest schedule that did (Blocked-Matched; BM) or did not (Blocked-Unmatched; BU) control for retroactive inhibition. …”
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154
Paeonol oxime inhibits bFGF-induced angiogenesis and reduces VEGF levels in fibrosarcoma cells.
Published 2010-01-01“…The treatment with PO blocked bFGF-stimulated migration and in vitro capillary differentiation (tube formation) in a dose-dependent manner. …”
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155
Nematode Assemblages Development Twenty-One Years after the Introduction of Meadow Soil into Bare Post Mining Spoil Heap
Published 2022-07-01“…The soil samples were taken at the beginning of the experiment (1997) and then, after 19 years (2016), were transported into blocks (B) in their surroundings in a 2 m distance (I) and, finally, 30 m from the transported blocks as a control (C), to compare and assess the complexity of soil food web. …”
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156
Uptake of Biotinylated Spermine in Astrocytes: Effect of Cx43 siRNA, HIV-Tat Protein and Polyamine Transport Inhibitor on Polyamine Uptake
Published 2021-08-01“…Using a novel polyamine transport inhibitor (PTI), trimer 44NMe, we blocked b-SPM uptake, showing that PA uptake is via a PTI-sensitive transport mechanism such as organic cation transporter. …”
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157
Structural Motifs in Aryl Organogermanium Ge-O Derivatives for Material Design
Published 2023-09-01“…The structural types of these compounds were considered, providing 11 blocks (<b>A</b>–<b>K</b>). The molecular structures of the novel compounds [(<i>p</i>-FC<sub>6</sub>H<sub>4</sub>)<sub>3</sub>Ge]<sub>2</sub>O (<b>1</b>), [(<i>p</i>-F<sub>3</sub>CC<sub>6</sub>H<sub>4</sub>)<sub>3</sub>Ge]<sub>2</sub>O (<b>2</b>), and <i>cyclo</i>-[(<i>p</i>-F<sub>3</sub>CC<sub>6</sub>H<sub>4</sub>)<sub>2</sub>GeO]<sub>4</sub> (<b>3</b>) were studied through XRD (X-ray diffraction) analysis. …”
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158
A Versatile Brij-Linker for One-Step Preparation of Targeted Nanoparticles
Published 2023-05-01“…Moreover, the targeting ligand density and thus the cell association of the nanoparticles is easily fine-tuned by selection of the initial ratio of the building blocks. <b>Conclusions</b>: This strategy might be a first step towards the one-step preparation of nanoparticles with tailored functionalities. …”
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159
Novel Targeted Therapies for Rheumatoid Arthritis Based on Intracellular Signalling and Immunometabolic Changes: A Narrative Review
Published 2024-01-01“…For example, rituximab therapy blocks B cell activation and abatacept effectively blocks T cell activation in patients with RA. …”
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160
Synthesis and Anti-Inflammatory Evaluation of a Library of Chiral Derivatives of Xanthones Conjugated with Proteinogenic Amino Acids
Published 2023-06-01“…Herein, the synthesis of a library of CDXs is described, by coupling a carboxyxanthone (<b>1</b>) with both enantiomers of proteinogenic amino esters as chiral building blocks (<b>2</b>–<b>31</b>), following the chiral pool strategy. …”
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