Neuropsychiatric Genetics of African Populations-Psychosis (NeuroGAP-Psychosis): a case-control study protocol and GWAS in Ethiopia, Kenya, South Africa and Uganda by Stevenson, A, Akena, D, Stroud, RE, Atwoli, L, Campbell, MM, Chibnik, LB, Kwobah, E, Kariuki, SM, Martin, AR, De Menil, V, Newton, CRJC, Sibeko, G, Stein, DJ, Teferra, S, Zingela, Z, Koenen, KC

“…<br/>DNA extraction will take place in-country, with genotyping performed at the Broad Institute. The primary analyses will include identifying major groups of participants with similar ancestry using the computation-efficient programme single nucleotide polymorphisms (SNP) weights. …”

Genetic analyses of the electrocardiographic QT interval and its components identify additional loci and pathways by William J. Young, Najim Lahrouchi, Aaron Isaacs, ThuyVy Duong, Luisa Foco, Farah Ahmed, Jennifer A. Brody, Reem Salman, Raymond Noordam, Jan-Walter Benjamins, Jeffrey Haessler, Leo-Pekka Lyytikäinen, Linda Repetto, Maria Pina Concas, Marten E. van den Berg, Stefan Weiss, Antoine R. Baldassari, Traci M. Bartz, James P. Cook, Daniel S. Evans, Rebecca Freudling, Oliver Hines, Jonas L. Isaksen, Honghuang Lin, Hao Mei, Arden Moscati, Martina Müller-Nurasyid, Casia Nursyifa, Yong Qian, Anne Richmond, Carolina Roselli, Kathleen A. Ryan, Eduardo Tarazona-Santos, Sébastien Thériault, Stefan van Duijvenboden, Helen R. Warren, Jie Yao, Dania Raza, Stefanie Aeschbacher, Gustav Ahlberg, Alvaro Alonso, Laura Andreasen, Joshua C. Bis, Eric Boerwinkle, Archie Campbell, Eulalia Catamo, Massimiliano Cocca, Michael J. Cutler, Dawood Darbar, Alessandro De Grandi, Antonio De Luca, Jun Ding, Christina Ellervik, Patrick T. Ellinor, Stephan B. Felix, Philippe Froguel, Christian Fuchsberger, Martin Gögele, Claus Graff, Mariaelisa Graff, Xiuqing Guo, Torben Hansen, Susan R. Heckbert, Paul L. Huang, Heikki V. Huikuri, Nina Hutri-Kähönen, M. Arfan Ikram, Rebecca D. Jackson, Juhani Junttila, Maryam Kavousi, Jan A. Kors, Thiago P. Leal, Rozenn N. Lemaitre, Henry J. Lin, Lars Lind, Allan Linneberg, Simin Liu, Peter W. MacFarlane, Massimo Mangino, Thomas Meitinger, Massimo Mezzavilla, Pashupati P. Mishra, Rebecca N. Mitchell, Nina Mononen, May E. Montasser, Alanna C. Morrison, Matthias Nauck, Victor Nauffal, Pau Navarro, Kjell Nikus, Guillaume Pare, Kristen K. Patton, Giulia Pelliccione, Alan Pittman, David J. Porteous, Peter P. Pramstaller, Michael H. Preuss, Olli T. Raitakari, Alexander P. Reiner, Antonio Luiz P. Ribeiro, Kenneth M. Rice, Lorenz Risch, David Schlessinger, Ulrich Schotten, Claudia Schurmann, Xia Shen, M. Benjamin Shoemaker, Gianfranco Sinagra, Moritz F. Sinner, Elsayed Z. Soliman, Monika Stoll, Konstantin Strauch, Kirill Tarasov, Kent D. Taylor, Andrew Tinker, Stella Trompet, André Uitterlinden, Uwe Völker, Henry Völzke, Melanie Waldenberger, Lu-Chen Weng, Eric A. Whitsel, James G. Wilson, Christy L. Avery, David Conen, Adolfo Correa, Francesco Cucca, Marcus Dörr, Sina A. Gharib, Giorgia Girotto, Niels Grarup, Caroline Hayward, Yalda Jamshidi, Marjo-Riitta Järvelin, J. Wouter Jukema, Stefan Kääb, Mika Kähönen, Jørgen K. Kanters, Charles Kooperberg, Terho Lehtimäki, Maria Fernanda Lima-Costa, Yongmei Liu, Ruth J. F. Loos, Steven A. Lubitz, Dennis O. Mook-Kanamori, Andrew P. Morris, Jeffrey R. O’Connell, Morten Salling Olesen, Michele Orini, Sandosh Padmanabhan, Cristian Pattaro, Annette Peters, Bruce M. Psaty, Jerome I. Rotter, Bruno Stricker, Pim van der Harst, Cornelia M. van Duijn, Niek Verweij, James F. Wilson, Dan E. Arking, Julia Ramirez, Pier D. Lambiase, Nona Sotoodehnia, Borbala Mifsud, Christopher Newton-Cheh, Patricia B. Munroe

Get full text

Time-Dependent Changes in Microglia Transcriptional Networks Following Traumatic Brain Injury by Saef Izzy, Saef Izzy, Saef Izzy, Saef Izzy, Qiong Liu, Qiong Liu, Zhou Fang, Zhou Fang, Zhou Fang, Zhou Fang, Sevda Lule, Sevda Lule, Limin Wu, Limin Wu, Joon Yong Chung, Joon Yong Chung, Aliyah Sarro-Schwartz, Aliyah Sarro-Schwartz, Alexander Brown-Whalen, Alexander Brown-Whalen, Caroline Perner, Caroline Perner, Caroline Perner, Suzanne E. Hickman, Suzanne E. Hickman, Suzanne E. Hickman, David L. Kaplan, Nikolaos A. Patsopoulos, Nikolaos A. Patsopoulos, Nikolaos A. Patsopoulos, Nikolaos A. Patsopoulos, Joseph El Khoury, Joseph El Khoury, Joseph El Khoury, Michael J. Whalen, Michael J. Whalen, Michael J. Whalen

Get full text

South Asian medical cohorts reveal strong founder effects and high rates of homozygosity by Jeffrey D. Wall, J. Fah Sathirapongsasuti, Ravi Gupta, Asif Rasheed, Radha Venkatesan, Saurabh Belsare, Ramesh Menon, Sameer Phalke, Anuradha Mittal, John Fang, Deepak Tanneeru, Manjari Deshmukh, Akshi Bassi, Jacqueline Robinson, Ruchi Chaudhary, Sakthivel Murugan, Zameer ul-Asar, Imran Saleem, Unzila Ishtiaq, Areej Fatima, Saqib Shafi Sheikh, Shahid Hameed, Mohammad Ishaq, Syed Zahed Rasheed, Fazal-ur-Rehman Memon, Anjum Jalal, Shahid Abbas, Philippe Frossard, Christian Fuchsberger, Lukas Forer, Sebastian Schoenherr, Qixin Bei, Tushar Bhangale, Jennifer Tom, Santosh Gopi Krishna Gadde, Priya B V, Naveen Kumar Naik, Minxian Wang, Pui-Yan Kwok, Amit V. Khera, B. R. Lakshmi, Adam S. Butterworth, Rajiv Chowdhury, John Danesh, Emanuele di Angelantonio, Aliya Naheed, Vinay Goyal, Rukmini M. Kandadai, Hrishikesh Kumar, Rupam Borgohain, Adreesh Mukherjee, Pettarusp M. Wadia, Ravi Yadav, Soaham Desai, Niraj Kumar, Atanu Biswas, Pramod Kumar Pal, Uday B. Muthane, Shymal K. Das, Vedam L. Ramprasad, Prashanth L. Kukkle, Somasekar Seshagiri, Sekar Kathiresan, Arkasubhra Ghosh, V. Mohan, Danish Saleheen, Eric W. Stawiski, Andrew S. Peterson

Get full text

Molecular genetics of trauma exposure and PTSD by Ananda B. Amstadter, Adam Maihofer, Karestan C. Koenen, Caroline Nievergelt

Get full text

Global Intersection of Long Non-Coding RNAs with Processed and Unprocessed Pseudogenes in the Human Genome by Michael John Milligan, Erin eHarvey, Albert eYu, Ashleigh eMorgan, Caio eDamski, Daniela-Lee eSmith, Eden eZhang, Jothini eSivananthan, Jonathan eBerengut, Radhini eSubramaniam, Aleksandra eSkoric, Scott eCollins, Kevin V Morris, Kevin V Morris, Leonard eLipovich

“…As inputs to our algorithm, we imported three public repositories of pseudogenes: GENCODE v17 (processed and unprocessed, Ensembl 72); Retroposed Pseudogenes V5 (processed only) and Yale Pseudo60 (processed and unprocessed, Ensembl 60); two public lncRNA catalogs: Broad Institute, GENCODE v17; NCBI annotated piRNAs; and NHGRI clinical variants. …”
Get full text

Aire-dependent genes undergo Clp1-mediated 3’UTR shortening associated with higher transcript stability in the thymus by Clotilde Guyon, Nada Jmari, Francine Padonou, Yen-Chin Li, Olga Ucar, Noriyuki Fujikado, Fanny Coulpier, Christophe Blanchet, David E Root, Matthieu Giraud

Get full text

On the limits of fitting complex models of population history to f-statistics by Robert Maier, Pavel Flegontov, Olga Flegontova, Ulaş Işıldak, Piya Changmai, David Reich

Get full text

Assessment of computational methods for the analysis of single-cell ATAC-seq data by Huidong Chen, Caleb Lareau, Tommaso Andreani, Michael E. Vinyard, Sara P. Garcia, Kendell Clement, Miguel A. Andrade-Navarro, Jason D. Buenrostro, Luca Pinello

Get full text

Beth Levine’s Legacy: From the Discovery of BECN1 to Therapies. A Mentees’ Perspective by Zhenyi An, Wei-Chung Chiang, Álvaro F. Fernández, Luis H. Franco, CongCong He, Shu-Yi Huang, Eunmyong Lee, Yang Liu, Salwa Sebti, Sanae Shoji-Kawata, Shyam Sirasanagandla, Richard C. Wang, Yongjie Wei, Yuting Zhao, Silvia Vega-Rubin-de-Celis

Get full text

Genomic signatures of past and present chromosomal instability in Barrett’s esophagus and early esophageal adenocarcinoma by Chunyang Bao, Richard W. Tourdot, Gregory J. Brunette, Chip Stewart, Lili Sun, Hideo Baba, Masayuki Watanabe, Agoston T. Agoston, Kunal Jajoo, Jon M. Davison, Katie S. Nason, Gad Getz, Kenneth K. Wang, Yu Imamura, Robert Odze, Adam J. Bass, Matthew D. Stachler, Cheng-Zhong Zhang

Get full text

Comparative genomics of Australian isolates of the wheat stem rust pathogen Puccinia graminis f. sp. tritici reveals extensive polymorphism in candidate effector genes by Narayana Mithur Upadhyaya, Diana P Garnica, Haydar eKaraoglu, Adnane eNemri, Jana eSperschneider, Bo eXu, Rohit eMago, Christina eCuomo, John P Rathjen, Robert F Park, Jeffrey G Ellis, Peter N Dodds

Get full text

Novel Epigenetic Clock Biomarkers of Age-Related Macular Degeneration by Saurav Mallik, Fran Grodstein, David A. Bennett, Demetrios G. Vavvas, Bernardo Lemos, Bernardo Lemos

Get full text

External signals regulate continuous transcriptional states in hematopoietic stem cells by Eva M Fast, Audrey Sporrij, Margot Manning, Edroaldo Lummertz Rocha, Song Yang, Yi Zhou, Jimin Guo, Ninib Baryawno, Nikolaos Barkas, David Scadden, Fernando Camargo, Leonard I Zon

Get full text

Genomic landscape of high-grade meningiomas by Wenya Linda Bi, Noah F. Greenwald, Malak Abedalthagafi, Jeremiah Wala, Will J. Gibson, Pankaj K. Agarwalla, Peleg Horowitz, Steven E. Schumacher, Ekaterina Esaulova, Yu Mei, Aaron Chevalier, Matthew A. Ducar, Aaron R. Thorner, Paul van Hummelen, Anat O. Stemmer-Rachamimov, Maksym Artyomov, Ossama Al-Mefty, Gavin P. Dunn, Sandro Santagata, Ian F. Dunn, Rameen Beroukhim

Get full text

Inductively coupled, transmit-receive coils for proton MRI and X-nucleus MRI/MRS in small animals by Atsushi M. Takahashi, Jitendra Sharma, David O. Guarin, Julie Miller, Hiroaki Wakimoto, Daniel P. Cahill, Yi-Fen Yen

Get full text

FungiDB: An Integrated Bioinformatic Resource for Fungi and Oomycetes by Evelina Y. Basenko, Jane A. Pulman, Achchuthan Shanmugasundram, Omar S. Harb, Kathryn Crouch, David Starns, Susanne Warrenfeltz, Cristina Aurrecoechea, Christian J. Stoeckert, Jessica C. Kissinger, David S. Roos, Christiane Hertz-Fowler

“…FungiDB is one of the largest EuPathDB databases containing nearly 100 genomes obtained from GenBank, Aspergillus Genome Database (AspGD), The Broad Institute, Joint Genome Institute (JGI), Ensembl, and other sources. …”
Get full text

Learning functional conservation between human and pig to decipher evolutionary mechanisms underlying gene expression and complex traits by Jinghui Li, Tianjing Zhao, Dailu Guan, Zhangyuan Pan, Zhonghao Bai, Jinyan Teng, Zhe Zhang, Zhili Zheng, Jian Zeng, Huaijun Zhou, Lingzhao Fang, Hao Cheng

Get full text

Intronic regulation of SARS-CoV-2 receptor (ACE2) expression mediated by immune signaling and oxidative stress pathways by Daniel Richard, Pushpanathan Muthuirulan, Jennifer Aguiar, Andrew C. Doxey, Arinjay Banerjee, Karen Mossman, Jeremy Hirota, Terence D. Capellini

Get full text

Serum protein profiling of lung, pancreatic, and colorectal cancers reveals alcohol consumption-mediated disruptions in early-stage cancer detection by Hanjun Lee, Seo Yihl Kim, Dong Wook Kim, Young Soo Park, Jin-Hyeok Hwang, Sukki Cho, Je-Yoel Cho

Get full text