Label-free cell segmentation of diverse lymphoid tissues in 2D and 3D by John W. Wills, Jack Robertson, Pani Tourlomousis, Clare M.C. Gillis, Claire M. Barnes, Michelle Miniter, Rachel E. Hewitt, Clare E. Bryant, Huw D. Summers, Jonathan J. Powell, Paul Rees

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Small-Molecule Screen Identifies De Novo Nucleotide Synthesis as a Vulnerability of Cells Lacking SIRT3 by Karina N. Gonzalez Herrera, Elma Zaganjor, Yoshinori Ishikawa, Jessica B. Spinelli, Haejin Yoon, Jia-Ren Lin, F. Kyle Satterstrom, Alison Ringel, Stacy Mulei, Amanda Souza, Joshua M. Gorham, Craig C. Benson, Jonathan G. Seidman, Peter K. Sorger, Clary B. Clish, Marcia C. Haigis

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Identification and Characterization of a Novel Protein ASP-3 Purified from <i>Arca subcrenata</i> and Its Antitumor Mechanism by Zhongyi Guo, Hui Shi, Chunlei Li, Yuanyuan Luo, Sixue Bi, Rongmin Yu, Haoran Wang, Wanying Liu, Jianhua Zhu, Weijuan Huang, Liyan Song

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Author Correction: Community-wide hackathons to identify central themes in single-cell multi-omics by Kim-Anh Lê Cao, Al J. Abadi, Emily F. Davis-Marcisak, Lauren Hsu, Arshi Arora, Alexis Coullomb, Atul Deshpande, Yuzhou Feng, Pratheepa Jeganathan, Melanie Loth, Chen Meng, Wancen Mu, Vera Pancaldi, Kris Sankaran, Dario Righelli, Amrit Singh, Joshua S. Sodicoff, Genevieve L. Stein-O’Brien, Ayshwarya Subramanian, Joshua D. Welch, Yue You, Ricard Argelaguet, Vincent J. Carey, Ruben Dries, Casey S. Greene, Susan Holmes, Michael I. Love, Matthew E. Ritchie, Guo-Cheng Yuan, Aedin C. Culhane, Elana Fertig

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Diet, Genetics, and the Gut Microbiome Drive Dynamic Changes in Plasma Metabolites by Shiho Fujisaka, Julian Avila-Pacheco, Marion Soto, Aleksandar Kostic, Jonathan M. Dreyfuss, Hui Pan, Siegfried Ussar, Emrah Altindis, Ning Li, Lynn Bry, Clary B. Clish, C. Ronald Kahn

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Large anatomical changes in head-and-neck cancers – A dosimetric comparison of online and offline adaptive proton therapy by Mislav Bobić, Arthur Lalonde, Konrad P. Nesteruk, Hoyeon Lee, Lena Nenoff, Bram L. Gorissen, Alejandro Bertolet, Paul M. Busse, Annie W. Chan, Brian A. Winey, Gregory C. Sharp, Joost M. Verburg, Antony J. Lomax, Harald Paganetti

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Whole brain delivery of an instability-prone Mecp2 transgene improves behavioral and molecular pathological defects in mouse models of Rett syndrome by Mirko Luoni, Serena Giannelli, Marzia Tina Indrigo, Antonio Niro, Luca Massimino, Angelo Iannielli, Laura Passeri, Fabio Russo, Giuseppe Morabito, Piera Calamita, Silvia Gregori, Benjamin Deverman, Vania Broccoli

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Glyco-centric lectin magnetic bead array (LeMBA) − proteomics dataset of human serum samples from healthy, Barrett׳s esophagus and esophageal adenocarcinoma individuals by Alok K. Shah, Kim-Anh Lê Cao, Eunju Choi, David Chen, Benoît Gautier, Derek Nancarrow, David C. Whiteman, Peter R. Baker, Karl R. Clauser, Robert J. Chalkley, Nicholas A. Saunders, Andrew P. Barbour, Virendra Joshi, Michelle M. Hill

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Assessment of treatment response in cardiac sarcoidosis based on myocardial 18F-FDG uptake by Lukas Frischknecht, Jan Schaab, Eloi Schmauch, Eloi Schmauch, Eloi Schmauch, Ayla Yalamanoglu, Dennis D. Arnold, Judith Schwaiger, Christiane Gruner, Ronny R. Buechel, Daniel P. Franzen, Antonios G.A. Kolios, Antonios G.A. Kolios, Jakob Nilsson

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CIP2A Constrains Th17 Differentiation by Modulating STAT3 Signaling by Mohd Moin Khan, Ubaid Ullah, Meraj H. Khan, Lingjia Kong, Robert Moulder, Tommi Välikangas, Santosh Dilip Bhosale, Elina Komsi, Omid Rasool, Zhi Chen, Laura L. Elo, Jukka Westermarck, Riitta Lahesmaa

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Pan-cancer integrated bioinformatics analysis reveals cuproptosis related gene FDX1 is a potential prognostic and immunotherapeutic biomarker for lower-grade gliomas by Wei Huang, Yuliang Wu, Yuliang Wu, Jihui Zhu, Ning Luo, Chunyan Wang, Shupeng Liu, Zhongping Cheng

“…FDX1 mRNA and clinical data were obtained from The Cancer Genome Atlas (TCGA), Genotype-Tissue Expression (GTEx), and Broad Institute Cancer Cell Line Encyclopedia (CCLE) databases. …”
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Large scale proteomic studies create novel privacy considerations by Andrew C. Hill, Claire Guo, Elizabeth M. Litkowski, Ani W. Manichaikul, Bing Yu, Iain R. Konigsberg, Betty A. Gorbet, Leslie A. Lange, Katherine A. Pratte, Katerina J. Kechris, Matthew DeCamp, Marilyn Coors, Victor E. Ortega, Stephen S. Rich, Jerome I. Rotter, Robert E. Gerzsten, Clary B. Clish, Jeffrey L. Curtis, Xiaowei Hu, Ma-en Obeidat, Melody Morris, Joseph Loureiro, Debby Ngo, Wanda K. O’Neal, Deborah A. Meyers, Eugene R. Bleecker, Brian D. Hobbs, Michael H. Cho, Farnoush Banaei-Kashani, Russell P. Bowler

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Intrapersonal Stability of Plasma Metabolomic Profiles over 10 Years among Women by Oana A. Zeleznik, Clemens Wittenbecher, Amy Deik, Sarah Jeanfavre, Julian Avila-Pacheco, Bernard Rosner, Kathryn M. Rexrode, Clary B. Clish, Frank B. Hu, A. Heather Eliassen

“…We quantified plasma metabolomics using two liquid chromatography mass spectrometry platforms (lipids and polar metabolites) at the Broad Institute (Cambridge, MA, USA). Intra-class correlations (ICC) were used to estimate long-term (10 years) within-person stability of metabolites and were calculated as the proportion of the total variability (within-person + between-person) attributable to between-person variability. …”
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Natural language processing and expert follow-up establishes tachycardia association with CDKL5 deficiency disorder by Alina Ivaniuk, Christian M. Boßelmann, Xiaoming Zhang, Mark St. John, Sara C. Taylor, Gokul Krishnaswamy, Alex Milinovich, Peter F. Aziz, Elia Pestana-Knight, Dennis Lal

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Genome-Wide Analyses for Osteosarcoma in Leonberger Dogs Reveal the <i>CDKN2A/B</i> Gene Locus as a Major Risk Locus by Anna Letko, Katie M. Minor, Elaine M. Norton, Voichita D. Marinescu, Michaela Drögemüller, Emma Ivansson, Kate Megquier, Hyun Ji Noh, Mike Starkey, Steven G. Friedenberg, Kerstin Lindblad-Toh, James R. Mickelson, Cord Drögemüller

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An effective hyper-parameter can increase the prediction accuracy in a single-step genetic evaluation by Mehdi Neshat, Mehdi Neshat, Mehdi Neshat, Soohyun Lee, Md. Moksedul Momin, Md. Moksedul Momin, Md. Moksedul Momin, Md. Moksedul Momin, Buu Truong, Buu Truong, Buu Truong, Buu Truong, Julius H. J. van der Werf, S. Hong Lee, S. Hong Lee, S. Hong Lee

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Identifying the metabolomic fingerprint of high and low flavonoid consumers by Kerry L. Ivey, Eric B. Rimm, Peter Kraft, Clary B. Clish, Aedin Cassidy, Jonathan Hodgson, Kevin Croft, Brian Wolpin, Liming Liang

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Pathway-specific alterations in striatal excitability and cholinergic modulation in a SAPAP3 mouse model of compulsive motor behavior by Jeffrey M. Malgady, Alexander Baez, Zachary B. Hobel, Kimberly Jimenez, Jack Goldfried, Eric M. Prager, Jennifer A. Wilking, Qiangge Zhang, Guoping Feng, Joshua L. Plotkin

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High-efficiency purification of divergent AAV serotypes using AAVX affinity chromatography by Michael Florea, Fotini Nicolaou, Simon Pacouret, Eric M. Zinn, Julio Sanmiguel, Eva Andres-Mateos, Carmen Unzu, Amy J. Wagers, Luk H. Vandenberghe

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The Molecular and Neuropathological Consequences of Genetic Risk for Alzheimer's Dementia by Shinya Tasaki, Shinya Tasaki, Chris Gaiteri, Chris Gaiteri, Sara Mostafavi, Philip L. De Jager, Philip L. De Jager, David A. Bennett, David A. Bennett

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