Management dilemmas in pulmonary arterial hypertension associated with congenital heart disease by R. Condliffe, P. Clift, K. Dimopoulos, R.M.R. Tulloh

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Idiopathic pulmonary fibrosis: airway volume measurement identifies progressive disease on computed tomography scans by Thomas McLellan, Peter M. George, Paul Ford, Jan De Backer, Cedric Van Holsbeke, Benjamin Mignot, Nicholas J. Screaton, Alessandro Ruggiero, Muhunthan Thillai

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Comprehensive Periprocedural Transesophageal Echocardiography Is a Key to Success in Transcatheter Mitral Valve Repair∗ by Carla de Sousa, MD, Elena Surkova, MD, PhD, Stamatios Lerakis, MD

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Oxidation of Atg3 and Atg7 mediates inhibition of autophagy by Karen Frudd, Thomas Burgoyne, Joseph Robert Burgoyne

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Editorial: Future research questions for improving COPD diagnosis and care by Ahmed S. Sadaka, Azmy Faisal, Justin L. Garner, Justin L. Garner, Amany F. Elbehairy

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Eisenmenger syndrome in an adult patient with a large patent ductus arteriosus by Konstantinos Dimopoulos

“…This is the case of a young female who was seen at our adult congenital heart disease and pulmonary hypertension service (Royal Brompton Hospital, London, UK) at the age of 17 years. …”
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Is there a role for renin–angiotensin–aldosterone system and neprilysin inhibition in the failing systemic right ventricle? by Diamantis Kosmidis, Alexandra Arvanitaki, George Giannakoulas

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Spastic Paraparesis Following Cocaine Inhalation by Henry Oluwasefunmi Savage, Malin Roesner, David Cohen

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The Utility of CMR Imaging to Differentiate Between Physiological Left Ventricular Enlargement and Mildly Depressed Resting Systolic Function and Athletic Individuals with Dilated... by Sarandeep Marwaha, BSc, Lisa Anderson, Nicholas Bunce, Raghav Bhatia, Shafik Khoury, MD, Sabiha Gati, MD, PhD, BSc, Sanjay Prasad, MD, PhD, Michael Papadakis, MD, Sanjay Sharma, MD

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The breathless swimmer: could this be swimming-induced pulmonary edema? by James H. Hull, Mathew G. Wilson

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Cardiac diffusion-weighted and tensor imaging: A consensus statement from the special interest group of the Society for Cardiovascular Magnetic Resonance by Erica Dall’Armellina, Daniel B. Ennis, Leon Axel, Pierre Croisille, Pedro F. Ferreira, Alexander Gotschy, David Lohr, Kevin Moulin, Christopher T. Nguyen, Sonja Nielles-Vallespin, William Romero, Andrew D. Scott, Christian Stoeck, Irvin Teh, Elizabeth M. Tunnicliffe, Magalie Viallon, Victoria Wang, Alistair A. Young, Jürgen E. Schneider, David E. Sosnovik

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Associations of genetically predicted vitamin D status and deficiency with the risk of carotid artery plaque: a Mendelian randomization study by Devendra Meena, Marie-Joe Dib, Jingxian Huang, Alexander Smith, Jian Huang, Amrit S. Lota, Sanjay K. Prasad, Dipender Gill, Abbas Dehghan, Ioanna Tzoulaki

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Phenotypic comparison between smoking and non-smoking chronic obstructive pulmonary disease by Sundeep S. Salvi, Bill B. Brashier, Jyoti Londhe, Kanchan Pyasi, Vandana Vincent, Shilpa S. Kajale, Sajid Tambe, Kuldeep Mandani, Arjun Nair, Sze Mun Mak, Sapna Madas, Sanjay Juvekar, Louise E. Donnelly, Peter J. Barnes

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Minimal clinically important difference for asthma endpoints: an expert consensus report by Matteo Bonini, Marcello Di Paolo, Diego Bagnasco, Ilaria Baiardini, Fulvio Braido, Marco Caminati, Elisiana Carpagnano, Marco Contoli, Angelo Corsico, Stefano Del Giacco, Enrico Heffler, Carlo Lombardi, Ilaria Menichini, Manlio Milanese, Nicola Scichilone, Gianenrico Senna, Giorgio W. Canonica

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Mechanical circulatory support in ventricular arrhythmias by Guido Tavazzi, Guido Tavazzi, Valentino Dammassa, Valentino Dammassa, Costanza Natalia Julia Colombo, Eloisa Arbustini, Thomas Castelein, Martin Balik, Christophe Vandenbriele, Christophe Vandenbriele, Christophe Vandenbriele

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The Role of Cardiovascular Magnetic Resonance Imaging in the Assessment of Myocardial Fibrosis in Young and Veteran Athletes: Insights From a Meta-Analysis by Emmanuel Androulakis, Dimitrios Mouselimis, Anastasios Tsarouchas, Alexios Antonopoulos, Constantinos Bakogiannis, Panagiotis Papagkikas, Charalambos Vlachopoulos

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Case report: marfan syndrome (MFS) mimicking cutaneous vasculitis by Fiona Price-Kuehne, Ebun Omoyinmi, Maha Younes, Matthew Edwards, Despina Eleftheriou, Despina Eleftheriou, Paul Brogan, Paul Brogan

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Bilateral whole lung lavage in pulmonary alveolar proteinosis â A retrospective study by A. Silva, A. Moreto, C. Pinho, A. Magalhães, A. Morais, C. Fiuza

“…In this paper we evaluated and discuss bilateral WLL, namely the procedure work-up and the therapeutic efficacy.Six bilateral WLL performed through a careful adherence to a modified Royal Brompton Hospital (London) technique were carried out without major complications and were associated with clinical and functional improvement of the PAP patients submitted to this procedure.As there are benefits in terms of time, patient comfort and cost effectiveness compared to unilateral WLL, associated with the efficacy and safety observed, bilateral WLL seems to be a suitable first choice for therapeutic lavage in PAP patients. …”
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Eisenmenger syndrome: current perspectives by Nashat H, Kempny A, McCabe C, Price LC, Harries C, Alonso-Gonzalez R, Gatzoulis MA, Wort SJ, Dimopoulos K

“…Heba Nashat,1–3 Aleksander Kempny,1–3 Colm McCabe,1 Laura C Price,1–3 Carl Harries,1 Rafael Alonso-Gonzalez,1–3 Michael A Gatzoulis,1–3 Stephen J Wort,1–3 Konstantinos Dimopoulos1–3 1Adult Congenital Heart Centre and National Centre for Pulmonary Hypertension, Royal Brompton Hospital, 2National Heart and Lung Institute (NHLI), Imperial College, 3National Institute for Health Research (NIHR) Cardiovascular Biomedical Research Unit, Royal Brompton Hospital and National Heart and Lung Institute, Imperial College, London, UK Abstract: Eisenmenger syndrome (ES) is the most severe form of pulmonary arterial hypertension (PAH) related to congenital heart disease (CHD). …”
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Leptospirosis as an important differential of pulmonary haemorrhage on the intensive care unit: a case managed with VV-ECMO by James Barnacle, Stefan Gurney, Stephane Ledot, Suveer Singh

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