The first Pd-catalyzed Buchwald–Hartwig aminations at C-2 or C-4 in the estrone series by Ildikó Bacsa, Dávid Szemerédi, János Wölfling, Gyula Schneider, Lilla Fekete, Erzsébet Mernyák

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A Second-Generation Palladacycle Architecture Bearing a N-Heterocyclic Carbene and Its Catalytic Behavior in Buchwald–Hartwig Amination Catalysis by Sylwia Ostrowska, Lorenzo Palio, Agnieszka Czapik, Subhrajyoti Bhandary, Marcin Kwit, Kristof Van Hecke, Steven P. Nolan

“…The readily accessible complexes exhibit high catalytic activity in the Buchwald–Hartwig amination. This is achieved using low catalyst loading and mild reaction conditions in a green solvent.…”
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Probing the origin of higher efficiency of terphenyl phosphine over the biaryl framework in Pd-catalyzed C-N coupling: A combined DFT and machine learning study by Qingfu Ye, Yu Zhao, Jun Zhu

Subjects: “…Buchwald–Hartwig amination…”
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Ligand Effects of BrettPhos and RuPhos on Rate-Limiting Steps in Buchwald–Hartwig Amination Reaction Due to the Modulation of Steric Hindrance and Electronic Structure by Jiaqi Tian, Gaobo Wang, Zheng-Hang Qi, Jing Ma

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Recent Applications of Pd-Catalyzed Suzuki–Miyaura and Buchwald–Hartwig Couplings in Pharmaceutical Process Chemistry by Balaram S. Takale, Fan-Yi Kong, Ruchita R. Thakore

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Synthesis of New N-Arylpyrimidin-2-amine Derivatives Using a Palladium Catalyst by So Ha Lee, Jae Chun Ryu, Ibrahim Mustafa El-Deeb

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A Slug Flow Platform with Multiple Process Analytics Facilitates Flexible Reaction Optimization by Florian Wagner, Peter Sagmeister, Clemens E. Jusner, Thomas G. Tampone, Vidhyadhar Manee, Frederic G. Buono, Jason D. Williams, C. Oliver Kappe

Subjects: “…Buchwald–Hartwig amination…”
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Recent Progress Concerning the <i>N</i>-Arylation of Indoles by Petr Oeser, Jakub Koudelka, Artem Petrenko, Tomáš Tobrman

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Synthetic Approaches to Piperazine-Containing Drugs Approved by FDA in the Period of 2011–2023 by Maria Novella Romanelli, Laura Braconi, Alessio Gabellini, Dina Manetti, Giambattista Marotta, Elisabetta Teodori

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Trifluoromethoxypyrazines: Preparation and Properties by Taras M. Sokolenko, Yurii L. Yagupolskii

“…As trifluoromethoxy-substituted pyrazines are still unknown, we have developed efficient and scalable methods for 2-chloro-5-trifluoromethoxypyrazine synthesis, showing the synthetic utility of this molecule for Buchwald-Hartwig amination and the Kumada-Corriu and Suzuki and Sonogashira coupling reactions. …”
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Rapid Construction of a Chloromethyl-Substituted Duocarmycin-like Prodrug by Christoffer Bengtsson, Ylva Gravenfors

“…The 1,2,3,6-tetrahydropyrrolo[3,2-<i>e</i>]indole-containing core is here constructed from commercially available Boc-5-bromoindole in four steps and 23% overall yield, utilizing a Buchwald–Hartwig amination followed by a sodium hydride-induced regioselective bromination. …”
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Palladium-catalyzed cross-couplings in the synthesis of agrochemicals by Yuxin Zhu, Wenfeng Dong, Wenjun Tang

“…In this review, the applications of palladium-catalyzed Heck reaction, Suzuki-Miyaura cross-coupling, Sonogashira coupling, Negishi cross-coupling, carbonylation, and Buchwald-Hartwig amination, in the synthesis of agrochemicals are summarized with particular emphasis on catalyst system and catalytic efficiencies. …”
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Reactions of 3-Hydroxy-2-phenyl-1<i>H</i>-benzo[<i>e</i>]isoindol-1-one: A Route to 3-Hydroxy-/3-anilinobenzo[<i>e</i>]indan-1-ones and Benzo[<i>f</i>]phthalazin-1(2<i>H</i>)-ones by Zbigniew Malinowski, Emilia Fornal, Anna Stachniuk, Monika Nowak

“…The target derivative <b>16</b> was obtained from the corresponding bromolactam <b>15</b> by the Buchwald–Hartwig amination. Structures of the obtained compounds were confirmed by the NMR spectra.…”
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Synthesis of Computationally Designed 2,5(6)-Benzimidazole Derivatives via Pd-Catalyzed Reactions for Potential <i>E. coli</i> DNA Gyrase B Inhibition by Rafael T. Aroso, Rita C. Guedes, Mariette M. Pereira

“…The challenging functionalization of the 5(6)-position was carried out via palladium-catalyzed Suzuki–Miyaura and Buchwald-Hartwig amination cross-coupling reactions between <i>N</i>-protected-5-bromo-2-nitrophenyl-benzimidazole and aryl boronic acids or sulfonylanilines, with yields up to 81%. …”
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Palladacyclic N-heterocyclic carbene precatalysts for transition metal catalysis by Kun Wang, Ruoqian Fan, Xian Wei, Weiwei Fang

“…Therefore, this review focuses mainly on the strategy of NHC-Pdcycles design and catalytic results obtained from representative transition metal catalysis, such as Suzuki-Miyaura, Heck-Mizoroki and Sonogashira cross-coupling reactions, Buchwald-Hartwig amination, carbonylation as well as arylation. …”
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Recent Achievements in the Copper-Catalyzed Arylation of Adamantane-Containing Amines, Di- and Polyamines by Alexei D. Averin, Svetlana P. Panchenko, Arina V. Murashkina, Varvara I. Fomenko, Daria S. Kuliukhina, Anna S. Malysheva, Alexei A. Yakushev, Anton S. Abel, Irina P. Beletskaya

“…Rapid development of the copper-catalyzed amination of aryl halides in the beginning of the 21st century, known as the Renaissance of the Ullmann chemistry, laid foundations for the use of this method as a powerful tool for the construction of the C(sp²)-N bond and became a rival of the Buchwald–Hartwig amination reaction. Various applications of this approach are well-documented in a number of comprehensive and more specialized reviews, and this overview in the form of a personal account of the Cu-catalyzed arylation and heteroarylation of the adamantane-containing amines, and di- and polyamines, covers a more specific area, showing the possibilities of the method and outlining general regularities, considering reagents structure, copper source and ligands, scope, and limitations. …”
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Acridine Based Small Molecular Hole Transport Type Materials for Phosphorescent OLED Application by Ramanaskanda Braveenth, Keunhwa Kim, Il-Ji Bae, Kanthasamy Raagulan, Bo Mi Kim, Miyoung Kim, Kyu Yun Chai

“…Two small molecular hole-transporting type materials, namely 4-(9,9-dimethylacridin-10(9<i>H</i>)-yl)-<i>N</i>-(4-(9,9-dimethylacridin-10(9<i>H</i>)-yl)phenyl)-<i>N</i>-phenylaniline (TPA-2ACR) and 10,10′-(9-phenyl-9<i>H</i>-carbazole-3,6-diyl)bis(9,9-dimethyl-9,10-dihydroacridine) (PhCAR-2ACR), were designed and synthesized using a single-step Buchwald–Hartwig amination between the dimethyl acridine and triphenylamine or carbazole moieties. …”
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The Benzothiazine Core as a Novel Motif for DNA-Binding Small Molecules by Milena Mlakić, Ivona Čipor, Petra Kovačec, Goran Kragol, Ana Ratković, Tatjana Kovačević, Rahela Zadravec, Valentina Milašinović, Krešimir Molčanov, Ivo Piantanida, Irena Škorić

“…Benzothiazine salts were synthesized either through the classical synthetic pathway using Buchwald–Hartwig amination or through economical and environmentally friendly electrochemical synthesis. …”
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Design, synthesis and cholinesterase inhibitory properties of new oxazole benzylamine derivatives by Ivana Šagud, Nikolina Maček Hrvat, Ana Grgičević, Tena Čadež, Josipa Hodak, Milena Dragojević, Kornelija Lasić, Zrinka Kovarik, Irena Škorić

“…Therefore, new trans-amino-4-/5-arylethenyl-oxazoles were designed and synthesised by the Buchwald-Hartwig amination of a previously synthesised trans-chloro-arylethenyloxazole derivative. …”
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Syntheses and Electrochemical and EPR Studies of Porphyrins Functionalized with Bulky Aromatic Amine Donors by Mary-Ambre Carvalho, Khalissa Merahi, Julien Haumesser, Ana Mafalda Vaz Martins Pereira, Nathalie Parizel, Jean Weiss, Maylis Orio, Vincent Maurel, Laurent Ruhlmann, Sylvie Choua, Romain Ruppert

“…A series of nickel(II) porphyrins bearing one or two bulky nitrogen donors at the <i>meso</i> positions were prepared by using Ullmann methodology or more classical Buchwald–Hartwig amination reactions to create the new C-N bonds. …”
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