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    Interleukin 10 Polymorphisms as Risk Factors for Progression to Chagas Disease Cardiomyopathy: A Case-Control Study and Meta-Analysis by Alicia Grijalva, Lucia Gallo Vaulet, Lucia Gallo Vaulet, Roberto Nicolas Agüero, Analia Toledano, Analia Toledano, Marikena Guadalupe Risso, Juan Quarroz Braghini, Juan Quarroz Braghini, David Sosa, David Sosa, Paula Ruybal, Silvia Repetto, Silvia Repetto, Catalina Dirney Alba Soto, Catalina Dirney Alba Soto

    Published 2022-07-01
    “…We carried out a case control study to explore the association between IL-10-1082G>A (rs18008969), -819C>T (rs1800871), -592A>C (rs1800872) polymorphisms and CCC in a population attending a hospital in Buenos Aires Argentina. Next, a systematic review of the literature and a meta-analysis were conducted combining present and previous studies to further study this association.MethodsOur case control study included 122 individuals with chronic T. cruzi infection including 64 patients with any degree of CCC and 58 asymptomatic individuals. …”
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