-
281
HOW TO ASSURE THE MOST APPROPRIATE DOSAGE OF ANTIMICROBIAL DRUGS
Published 2001-10-01“…On the</p><em><em></em></em><p align="LEFT">basis of the literature data we proposed markers to enhance</p><em><em></em></em><p align="LEFT">the prediction of clinical outcomes, e.g. time for which</p><em><em></em></em><p align="LEFT"><span style="font-family: GaramondItcTEE-LighItal; font-size: xx-small;"><span style="font-family: GaramondItcTEE-LighItal; font-size: xx-small;">drug plasma concentration exceeds MIC (t </span></span><span style="font-family: GaramondItcTEE-LighItal; font-size: xx-small;"><span style="font-family: GaramondItcTEE-LighItal; font-size: xx-small;">> MIC</span></span><span style="font-family: GaramondItcTEE-LighItal; font-size: xx-small;"><span style="font-family: GaramondItcTEE-LighItal; font-size: xx-small;">), ratio between</span></span></p><em><em></em></em><p align="LEFT">peak plasma concentration of antimicrobial drug and MIC</p><em><em></em></em><p align="LEFT"><span style="font-family: GaramondItcTEE-LighItal; font-size: xx-small;"><span style="font-family: GaramondItcTEE-LighItal; font-size: xx-small;">(C</span></span><span style="font-family: GaramondItcTEE-LighItal; font-size: xx-small;"><span style="font-family: GaramondItcTEE-LighItal; font-size: xx-small;">max </span></span><span style="font-family: GaramondItcTEE-LighItal; font-size: xx-small;"><span style="font-family: GaramondItcTEE-LighItal; font-size: xx-small;">/MIC) and area under the inhibitory curve (AUIC).…”
Get full text
Article -
282
Water level variation at a beaver pond significantly impacts net CO<sub>2</sub> uptake of a continental bog
Published 2023-01-01“…<p>The carbon (<span class="inline-formula">C</span>) dynamics of northern peatlands are sensitive to hydrological changes owing to ecohydrological feedbacks. …”
Get full text
Article -
283
Past and future climate change effects on the thermal regime and oxygen solubility of four peri-alpine lakes
Published 2023-02-01“…Based on the shared socio-economic pathway SSP370 of the Intergovernmental Panel on Climate Change (IPCC), peri-alpine lakes could face an increase of 3.80 <span class="inline-formula"><sup>∘</sup></span>C (<span class="inline-formula">±0.20</span> <span class="inline-formula"><sup>∘</sup></span>C) in the next 70 years, accompanied by a decline of 1.0 mg L<span class="inline-formula"><sup>−1</sup></span> (<span class="inline-formula">±0.1</span> mg L<span class="inline-formula"><sup>−1</sup></span>) of <span class="inline-formula">O<sub>2</sub></span> solubility. …”
Get full text
Article -
284
Identifying and correcting interferences to PTR-ToF-MS measurements of isoprene and other urban volatile organic compounds
Published 2024-01-01“…This study evaluates the extent to which fragmentation and other ionization processes impact urban measurements of the PTR-ToF-MS ions typically assigned to isoprene (<span class="inline-formula"><math xmlns="http://www.w3.org/1998/Math/MathML" id="M1" display="inline" overflow="scroll" dspmath="mathml"><mrow><mi>m</mi><mo>/</mo><mi>z</mi></mrow></math><span><svg:svg xmlns:svg="http://www.w3.org/2000/svg" width="23pt" height="14pt" class="svg-formula" dspmath="mathimg" md5hash="91270dba487782af7360c80516416e4b"><svg:image xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="amt-17-801-2024-ie00001.svg" width="23pt" height="14pt" src="amt-17-801-2024-ie00001.png"/></svg:svg></span></span> 69, C<span class="inline-formula"><sub>5</sub></span>H<span class="inline-formula"><sub>8</sub></span>H<span class="inline-formula"><sup>+</sup></span>), acetaldehyde (<span class="inline-formula"><math xmlns="http://www.w3.org/1998/Math/MathML" id="M5" display="inline" overflow="scroll" dspmath="mathml"><mrow><mi>m</mi><mo>/</mo><mi>z</mi></mrow></math><span><svg:svg xmlns:svg="http://www.w3.org/2000/svg" width="23pt" height="14pt" class="svg-formula" dspmath="mathimg" md5hash="46f32566b65c77f385ccc58250dc589d"><svg:image xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="amt-17-801-2024-ie00002.svg" width="23pt" height="14pt" src="amt-17-801-2024-ie00002.png"/></svg:svg></span></span> 45, CH<span class="inline-formula"><sub>3</sub></span>CHO<span class="inline-formula"><sup>+</sup></span>), and benzene (<span class="inline-formula"><math xmlns="http://www.w3.org/1998/Math/MathML" id="M8" display="inline" overflow="scroll" dspmath="mathml"><mrow><mi>m</mi><mo>/</mo><mi>z</mi></mrow></math><span><svg:svg xmlns:svg="http://www.w3.org/2000/svg" width="23pt" height="14pt" class="svg-formula" dspmath="mathimg" md5hash="d93d3cda2a0fb8602765a5ab31f8bec1"><svg:image xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="amt-17-801-2024-ie00003.svg" width="23pt" height="14pt" src="amt-17-801-2024-ie00003.png"/></svg:svg></span></span> 79, C<span class="inline-formula"><sub>6</sub></span>H<span class="inline-formula"><sub>6</sub></span>H<span class="inline-formula"><sup>+</sup></span>). …”
Get full text
Article -
285
Spatial and temporal variation in <i>δ</i><sup>13</sup>C values of methane emitted from a hemiboreal mire: methanogenesis, methanotrophy, and hysteresis
Published 2022-09-01“…According to the spatial <span class="inline-formula"><i>δ</i><sup>13</sup></span>C–<span class="inline-formula"><math xmlns="http://www.w3.org/1998/Math/MathML" id="M11" display="inline" overflow="scroll" dspmath="mathml"><mrow><msub><mi>F</mi><mrow class="chem"><msub><mi mathvariant="normal">CH</mi><mn mathvariant="normal">4</mn></msub></mrow></msub></mrow></math><span><svg:svg xmlns:svg="http://www.w3.org/2000/svg" width="23pt" height="14pt" class="svg-formula" dspmath="mathimg" md5hash="91e8853d44f64a0711d31d2192a7eb30"><svg:image xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="bg-19-4331-2022-ie00002.svg" width="23pt" height="14pt" src="bg-19-4331-2022-ie00002.png"/></svg:svg></span></span> relations, methanotrophy was unlikely to be the dominating cause for the spatial variation. …”
Get full text
Article -
286
Impacts of water partitioning and polarity of organic compounds on secondary organic aerosol over eastern China
Published 2020-06-01“…The correlation of <span class="inline-formula"><i>κ</i></span> with the <span class="inline-formula">O:C</span> ratio varies significantly across different cities and seasons. …”
Get full text
Article -
287
Modelling the terrestrial nitrogen and phosphorus cycle in the UVic ESCM
Published 2023-07-01“…<span class="inline-formula">CNP</span> simulation resulted in a reduction of 11 % of the mean GPP and a reduction of 23 % of the vegetation biomass compared to the baseline <span class="inline-formula">C</span> simulation. These results are in better agreement with observations, particularly in tropical regions where <span class="inline-formula">P</span> limitation is known to be important. …”
Get full text
Article -
288
Local-to-regional methane emissions from the Upper Silesian Coal Basin (USCB) quantified using UAV-based atmospheric measurements
Published 2023-05-01“…In addition, we also measured <span class="inline-formula"><i>δ</i><sup>13</sup>C</span>-<span class="inline-formula">CH<sub>4</sub></span>, <span class="inline-formula"><i>δ</i><sup>2</sup>H</span>-<span class="inline-formula">CH<sub>4</sub></span>, ambient temperature, pressure, relative humidity, surface wind speed, and surface wind direction. …”
Get full text
Article -
289
Organic matter characteristics of a rapidly eroding permafrost cliff in NE Siberia (Lena Delta, Laptev Sea region)
Published 2022-04-01“…The elevated ratio of iso- and anteiso-branched fatty acids (FAs) relative to mid- and long-chain (C <span class="inline-formula">≥</span> 20) <span class="inline-formula"><i>n</i></span>-FAs in the interstadial MIS 3 and the interglacial MIS 1 deposits suggests stronger microbial activity and consequently higher input of bacterial biomass during these climatically warmer periods. …”
Get full text
Article -
290
Unambiguous identification of N-containing oxygenated organic molecules using a chemical-ionization Orbitrap (CI-Orbitrap) in an eastern Chinese megacity
Published 2023-03-01“…The 2N-OOM<span class="inline-formula"><sub>Ali</sub></span> was the most abundant 2N-OOM, and its fraction even increased on the polluted day with an enhanced proportion of the ones with nC <span class="inline-formula"><i>></i>10</span>. …”
Get full text
Article -
291
<i>δ</i><sup>13</sup>C, CO<sub>2</sub> ∕ <sup>3</sup>He and <sup>3</sup>He ∕ <sup>4</sup>He ratios reveal the presence of mantle gas in the CO<sub>2</su...
Published 2022-05-01“…The combination of <span class="inline-formula"><i>δ</i><sup>13</sup>C</span> (between ca. <span class="inline-formula">−9 ‰</span> VPDB<span class="note-anchor" id="fna_Ch1.Footn1"><a href="#fn_Ch1.Footn1"><sup>1</sup></a></span> and <span class="inline-formula">−2 ‰</span> VPDB), <span class="inline-formula"><math xmlns="http://www.w3.org/1998/Math/MathML" id="M19" display="inline" overflow="scroll" dspmath="mathml"><mrow class="chem"><msub><mi mathvariant="normal">CO</mi><mn mathvariant="normal">2</mn></msub><msup><mo>/</mo><mn mathvariant="normal">3</mn></msup><mi mathvariant="normal">He</mi></mrow></math><span><svg:svg xmlns:svg="http://www.w3.org/2000/svg" width="48pt" height="16pt" class="svg-formula" dspmath="mathimg" md5hash="f571d99770c11306333b27ed5ca30b11"><svg:image xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="hess-26-2637-2022-ie00009.svg" width="48pt" height="16pt" src="hess-26-2637-2022-ie00009.png"/></svg:svg></span></span> ratio (between <span class="inline-formula">1.9×10<sup>8</sup></span> and <span class="inline-formula">2.9×10<sup>9</sup></span>) and <span class="inline-formula"><math xmlns="http://www.w3.org/1998/Math/MathML" id="M22" display="inline" overflow="scroll" dspmath="mathml"><mrow class="chem"><msup><mi/><mn mathvariant="normal">3</mn></msup><mi mathvariant="normal">He</mi><msup><mo>/</mo><mn mathvariant="normal">4</mn></msup><mi mathvariant="normal">He</mi></mrow></math><span><svg:svg xmlns:svg="http://www.w3.org/2000/svg" width="46pt" height="15pt" class="svg-formula" dspmath="mathimg" md5hash="5e8bb6b618862902b1a0e7bf75a65b08"><svg:image xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="hess-26-2637-2022-ie00010.svg" width="46pt" height="15pt" src="hess-26-2637-2022-ie00010.png"/></svg:svg></span></span> (between 0.92 and 2.70 Ra) shows with a high level of confidence that the <span class="inline-formula">CO<sub>2</sub></span> in the carbogaseous groundwater of Spa and Bru has a mantle origin. …”
Get full text
Article -
292
Fe-bearing vanadium dioxide–paramontroseite: structural details and high-temperature transformation
Published 2023-06-01“…Thermal expansion is anisotropic, leading to the following <span class="inline-formula"><i>β</i></span> coefficients: <span class="inline-formula"><math xmlns="http://www.w3.org/1998/Math/MathML" id="M15" display="inline" overflow="scroll" dspmath="mathml"><mrow><mo>-</mo><mn mathvariant="normal">2.0</mn><mo>×</mo><msup><mn mathvariant="normal">10</mn><mrow><mo>-</mo><mn mathvariant="normal">5</mn></mrow></msup></mrow></math><span><svg:svg xmlns:svg="http://www.w3.org/2000/svg" width="59pt" height="13pt" class="svg-formula" dspmath="mathimg" md5hash="4dfc02a6053a4294b6cbe98cdc222976"><svg:image xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="ejm-35-373-2023-ie00001.svg" width="59pt" height="13pt" src="ejm-35-373-2023-ie00001.png"/></svg:svg></span></span>, <span class="inline-formula"><math xmlns="http://www.w3.org/1998/Math/MathML" id="M16" display="inline" overflow="scroll" dspmath="mathml"><mrow><mn mathvariant="normal">3.0</mn><mo>×</mo><msup><mn mathvariant="normal">10</mn><mrow><mo>-</mo><mn mathvariant="normal">5</mn></mrow></msup></mrow></math><span><svg:svg xmlns:svg="http://www.w3.org/2000/svg" width="51pt" height="13pt" class="svg-formula" dspmath="mathimg" md5hash="8cc417b3ec8f921814a72838e9c03d99"><svg:image xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="ejm-35-373-2023-ie00002.svg" width="51pt" height="13pt" src="ejm-35-373-2023-ie00002.png"/></svg:svg></span></span>, <span class="inline-formula"><math xmlns="http://www.w3.org/1998/Math/MathML" id="M17" display="inline" overflow="scroll" dspmath="mathml"><mrow><mn mathvariant="normal">0.8</mn><mo>×</mo><msup><mn mathvariant="normal">10</mn><mrow><mo>-</mo><mn mathvariant="normal">5</mn></mrow></msup></mrow></math><span><svg:svg xmlns:svg="http://www.w3.org/2000/svg" width="51pt" height="13pt" class="svg-formula" dspmath="mathimg" md5hash="1e2705fa2131d85215d6eed4c0d0304c"><svg:image xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="ejm-35-373-2023-ie00003.svg" width="51pt" height="13pt" src="ejm-35-373-2023-ie00003.png"/></svg:svg></span></span> and <span class="inline-formula"><math xmlns="http://www.w3.org/1998/Math/MathML" id="M18" display="inline" overflow="scroll" dspmath="mathml"><mrow><mn mathvariant="normal">1.8</mn><mo>×</mo><msup><mn mathvariant="normal">10</mn><mrow><mo>-</mo><mn mathvariant="normal">5</mn></mrow></msup></mrow></math><span><svg:svg xmlns:svg="http://www.w3.org/2000/svg" width="51pt" height="13pt" class="svg-formula" dspmath="mathimg" md5hash="5851cc401e05a481a4c4a46ee741295c"><svg:image xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="ejm-35-373-2023-ie00004.svg" width="51pt" height="13pt" src="ejm-35-373-2023-ie00004.png"/></svg:svg></span></span> <span class="inline-formula"><sup>∘</sup></span>C<span class="inline-formula"><sup>−1</sup></span> for <span class="inline-formula"><i>a</i></span>, <span class="inline-formula"><i>b</i></span>, <span class="inline-formula"><i>c</i></span> and <span class="inline-formula"><i>V</i></span>, respectively. …”
Get full text
Article -
293
Tunnelled central venous catheter-related bloodstream infection in Canadian blood stem cell transplant recipients: Associated costs
Published 2015-07-01“…</em></p><p class="p1"><strong>K</strong><span class="s1"><strong>ey </strong></span><strong>words:</strong> c<span class="s1">atheter related b</span>loodstr<span class="s1">ea</span>m<span class="s1"> in</span>f<span class="s1">ec</span>t<span class="s1">i</span>on,cost,<span class="s1"> s</span>tem c<span class="s1">e</span>llt<span class="s1">ra</span>nspl<span class="s1">a</span>nt</p>…”
Get full text
Article -
294
Distinct diurnal variation in organic aerosol hygroscopicity and its relationship with oxygenated organic aerosol
Published 2020-01-01“…The derived <span class="inline-formula"><i>κ</i><sub>OA</sub></span> was highly correlated with <span class="inline-formula"><i>f</i><sub>44</sub></span> (fraction of <span class="inline-formula"><i>m</i>∕<i>z</i></span> 44 in OA measured by CV-ToF-ACSM), an indicator of the oxidation degree of OA (<span class="inline-formula"><i>R</i>=0.79</span>), and the relationship can be parameterized as <span class="inline-formula"><math xmlns="http://www.w3.org/1998/Math/MathML" id="M17" display="inline" overflow="scroll" dspmath="mathml"><mrow><msub><mi mathvariant="italic">κ</mi><mi mathvariant="normal">OA</mi></msub><mo>=</mo><mn mathvariant="normal">1.04</mn><mo>×</mo><msub><mi>f</mi><mn mathvariant="normal">44</mn></msub><mo>-</mo><mn mathvariant="normal">0.02</mn></mrow></math><span><svg:svg xmlns:svg="http://www.w3.org/2000/svg" width="111pt" height="12pt" class="svg-formula" dspmath="mathimg" md5hash="9890895a6671a6bb2a4f1ad14f52e15a"><svg:image xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="acp-20-865-2020-ie00001.svg" width="111pt" height="12pt" src="acp-20-865-2020-ie00001.png"/></svg:svg></span></span> (<span class="inline-formula"><math xmlns="http://www.w3.org/1998/Math/MathML" id="M18" display="inline" overflow="scroll" dspmath="mathml"><mrow><msub><mi mathvariant="italic">κ</mi><mi mathvariant="normal">OA</mi></msub><mo>=</mo><mn mathvariant="normal">0.3</mn><mo>×</mo><mrow class="chem"><mi mathvariant="normal">O</mi><mo>:</mo><mi mathvariant="normal">C</mi></mrow><mo>-</mo><mn mathvariant="normal">0.02</mn></mrow></math><span><svg:svg xmlns:svg="http://www.w3.org/2000/svg" width="116pt" height="13pt" class="svg-formula" dspmath="mathimg" md5hash="0c7ee3d913682589678ebfbabba540ac"><svg:image xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="acp-20-865-2020-ie00002.svg" width="116pt" height="13pt" src="acp-20-865-2020-ie00002.png"/></svg:svg></span></span>, based on the relationship between the <span class="inline-formula"><i>f</i><sub>44</sub></span> and <span class="inline-formula">O∕C</span> ratio for CV-ToF-ACSM). On average, <span class="inline-formula"><i>κ</i><sub>OA</sub></span> reached the minimum (0.02) in the morning near 07:30 local time (LT) and then increased rapidly, reaching the peak value of 0.16 near 14:30 LT. …”
Get full text
Article -
295
Contributions of biomass-burning, urban, and biogenic emissions to the concentrations and light-absorbing properties of particulate matter in central Amazonia during the dry season
Published 2019-06-01“…A decrease in <span class="inline-formula"><i>b</i><sub>abs,BrC</sub></span> was observed as the mass concentration of nitrogen-containing organic compounds decreased and the organic PM<span class="inline-formula"><sub>1</sub></span> <span class="inline-formula">O:C</span> ratio increased, suggesting atmospheric bleaching of the BrC components. …”
Get full text
Article -
296
Climate signals in stable carbon and hydrogen isotopes of lignin methoxy groups from southern German beech trees
Published 2022-08-01“…Initial <span class="inline-formula"><i>δ</i><sup>13</sup>C<sub>LM</sub></span> values were corrected for the Suess effect (a decrease of <span class="inline-formula"><i>δ</i><sup>13</sup>C</span> in atmospheric CO<span class="inline-formula"><sub>2</sub></span>) and physiological tree responses to increasing atmospheric CO<span class="inline-formula"><sub>2</sub></span> concentrations considering a range of published discrimination factors. …”
Get full text
Article -
297
Highest methane concentrations in an Arctic river linked to local terrestrial inputs
Published 2022-11-01“…These key sites were characterized by warm waters (<span class="inline-formula"><i>T</i>>14.5</span> <span class="inline-formula"><sup>∘</sup>C</span>) and low specific conductivities (<span class="inline-formula"><i>κ</i><88</span> <span class="inline-formula">µS cm<sup>−1</sup></span>). …”
Get full text
Article -
298
Global datasets of hourly carbon and water fluxes simulated using a satellite-based process model with dynamic parameterizations
Published 2024-03-01“…However, these models often estimate GPP and ET at coarse daily or monthly steps, hindering analysis of ecosystem dynamics at the diurnal (hourly) scales, and prescribe some essential parameters (i.e., the Ball–Berry slope (<span class="inline-formula"><i>m</i></span>) and the maximum carboxylation rate at 25 °C (<span class="inline-formula"><math xmlns="http://www.w3.org/1998/Math/MathML" id="M2" display="inline" overflow="scroll" dspmath="mathml"><mrow><msubsup><mi>V</mi><mi mathvariant="normal">cmax</mi><mn mathvariant="normal">25</mn></msubsup></mrow></math><span><svg:svg xmlns:svg="http://www.w3.org/2000/svg" width="27pt" height="16pt" class="svg-formula" dspmath="mathimg" md5hash="6843e2ad912be589c7d614809a188ea9"><svg:image xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="essd-16-1283-2024-ie00001.svg" width="27pt" height="16pt" src="essd-16-1283-2024-ie00001.png"/></svg:svg></span></span>)) as constant, inducing uncertainties in the estimates of GPP and ET. …”
Get full text
Article -
299
Johan Galtung, el devenir Histórico como proyecto existencial
Published 2009-06-01“…<p><span>E</span><span>l</span><span> </span><span>2009</span><span> </span><span>r</span><span>eco</span><span>r</span><span>damos</span><span> </span><span>los</span><span> </span><span>50</span><span> </span><span>años</span><span> </span><span>de</span><span> </span><span>la</span><span> </span><span>c</span><span>r</span><span>eación</span><span> </span><span>del</span><span> </span><span><em>I</em></span><span><em>nte</em></span><span><em>r</em></span><span><em>national</em></span><span><em> </em></span><span><em>P</em></span><span><em>eace</em></span><span><em> </em></span><span><em>R</em></span><span><em>esea</em></span><span><em>r</em></span><span><em>ch</em></span><span><em> </em></span><span><em>I</em></span><span><em>stitute </em></span><span><em>o</em></span><em>f</em><span><em> </em></span><span><em>Osl</em></span><em>o</em><span><em> </em></span><span>(IPRIO</span>)<span> </span>a<span> </span><span>iniciativ</span>a<span> </span><span>de</span>l<span> </span><span>matemátic</span>o<span> </span>y<span> </span><span>sociólog</span>o<span> </span><span>no</span><span>r</span><span>ueg</span>o<span> </span><span>J</span><span>oha</span>n<span> </span><span>Galtung</span>.…”
Get full text
Article -
300
Heterogeneity and chemical reactivity of the remote troposphere defined by aircraft measurements – corrected
Published 2023-01-01“…In this paper we present and analyze a data set of 10 s (2 km) merged and gap-filled observations of the key reactive species driving the chemical budgets of O<span class="inline-formula"><sub>3</sub></span> and CH<span class="inline-formula"><sub>4</sub></span> (O<span class="inline-formula"><sub>3</sub></span>, CH<span class="inline-formula"><sub>4</sub></span>, CO, H<span class="inline-formula"><sub>2</sub></span>O, HCHO, H<span class="inline-formula"><sub>2</sub></span>O<span class="inline-formula"><sub>2</sub></span>, CH<span class="inline-formula"><sub>3</sub></span>OOH, C<span class="inline-formula"><sub>2</sub></span>H<span class="inline-formula"><sub>6</sub></span>, higher alkanes, alkenes, aromatics, NO<span class="inline-formula"><sub><i>x</i></sub></span>, HNO<span class="inline-formula"><sub>3</sub></span>, HNO<span class="inline-formula"><sub>4</sub></span>, peroxyacetyl nitrate, and other organic nitrates), consisting of 146 494 distinct air parcels from ATom deployments 1 through 4. …”
Get full text
Article