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Topological Data Analysis of C. elegans Locomotion and Behavior
Published 2021-06-01Subjects: Get full text
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82
Chemical basis of microbiome preference in the nematode C. elegans
Published 2024-01-01“…We approach this question in the nematode C. elegans, which feeds on bacteria and also harbors an intestinal microbiome. …”
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83
Semaphorin signaling restricts neuronal regeneration in C. elegans
Published 2022-10-01Subjects: Get full text
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84
C. elegans neurons have functional dendritic spines
Published 2019-10-01“…However, spine-like protrusions have been reported in C. elegans (Philbrook et al., 2018), suggesting that the experimental advantages of smaller model organisms could be exploited to study the biology of dendritic spines. …”
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85
Germline Stem and Progenitor Cell Aging in C. elegans
Published 2021-07-01“…Like many animals and humans, reproduction in the nematode C. elegans declines with age. This decline is the cumulative result of age-related changes in several steps of germline function, many of which are highly accessible for experimental investigation in this short-lived model organism. …”
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86
Neuropeptidergic regulation of compulsive ethanol seeking in C. elegans
Published 2022-02-01“…We demonstrate that the C. elegans model recapitulated the pivotal features of compulsive alcohol seeking in mammals, specifically repeated attempts, endurance, and finally aversion-resistant alcohol seeking. …”
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87
Inversion of pheromone preference optimizes foraging in C. elegans
Published 2022Get full text
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88
The regulation of programmed and pathological cell death in C. elegans
Published 2007Get full text
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Genetic and molecular analysis of C. elegans vulval invagination
Published 2010Get full text
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Analysis of centriole elimination during C. elegans oogenesis.
Published 2012“…Here, we investigate this question in C. elegans. Using antibodies directed against centriolar components and serial-section electron microscopy, we establish that centrioles are eliminated during the diplotene stage of the meiotic cell cycle. …”
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An enhanced C. elegans based platform for toxicity assessment
Published 2017“…Strains identified in this work will also enhance the sensitivity of C. elegans based drug discovery platforms. …”
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94
C. elegans chromosomes connect to centrosomes by anchoring into the spindle network
Published 2017-05-01Get full text
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95
Shared behavioral mechanisms underlie C. elegans aggregation and swarming
Published 2019-04-01“…Here, we investigate collective feeding in the roundworm C. elegans at this intermediate scale, using quantitative phenotyping and agent-based modeling to identify behavioral rules underlying both aggregation and swarming—a dynamic phenotype only observed at longer timescales. …”
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96
Functional identification of microRNA-centered complexes in C. elegans
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97
Fasting prevents hypoxia-induced defects of proteostasis in C. elegans.
Published 2019-06-01“…We have shown that specific hypoxic conditions disrupt protein homeostasis in C. elegans, leading to protein aggregation and proteotoxicity. …”
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98
Two Wnts Instruct Topographic Synaptic Innervation in C. elegans
Published 2013-10-01“…Little is known about whether there are additional mechanisms for precise topographic mapping of synaptic connections. Whereas the C. elegans DA8 and DA9 neurons have similar axonal trajectories, their synapses are positioned in distinct but adjacent domains in the anterior-posterior axis. …”
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Insights Into the Links Between Proteostasis and Aging From C. elegans
Published 2022-03-01Subjects: Get full text
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100
A distributed chemosensory circuit for oxygen preference in C. elegans.
Published 2006-09-01“…The nematode Caenorhabditis elegans has complex, naturally variable behavioral responses to environmental oxygen, food, and other animals. C. elegans detects oxygen through soluble guanylate cyclase homologs (sGCs) and responds to it differently depending on the activity of the neuropeptide receptor NPR-1: npr-1(lf) and naturally isolated npr-1(215F) animals avoid high oxygen and aggregate in the presence of food; npr-1(215V) animals do not. …”
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