Clinical significance of CCL2 expression in osteosarcoma tissue by GONG Runze, HU Haiyan

“…CC chemokine ligand 2 (CCL2) and tis receptor CC chemokine ligand receptor 2 (CCR2) may take part in tumor. …”
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Role of CCL2/MCP-1 in Islet Transplantation by Raffaella Melzi, Alessia Mercalli, Valeria Sordi, Elisa Cantarelli, Rita Nano, Paola Maffi, Giovanni Sitia, Luca G. Guidotti, Antonio Secchi, Ezio Bonifacio, Lorenzo Piemonti

“…High levels of donor-derived CCL2 have been associated with poor islet allograft outcome in patients with type 1 diabetes. …”
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Morphine stimulates CCL2 production by human neurons by Sheng Wen S, Hu Shuxian, Rock R Bryan, Peterson Phillip K

“…</p> <p>Results</p> <p>Morphine upregulated CCL2 mRNA and protein in neuronal cultures in a concentration- and time-dependent fashion, but had no effect on CCL2 production in astrocyte or microglial cell cultures. …”
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CCL2/MCP-1 modulation of microglial activation and proliferation by Garcia-Bueno Borja, Hinojosa Ara E, Leza Juan C, Madrigal Jose LM

“…<p>Abstract</p> <p>Background</p> <p>Monocyte chemoattractant protein (CCL2/MCP-1) is a chemokine that attracts cells involved in the immune/inflammatory response. …”
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Stimulation of MMP-1 and CCL2 by NAMPT in PDL Cells by Marjan Nokhbehsaim, Sigrun Eick, Andressa Vilas Boas Nogueira, Per Hoffmann, Stefan Herms, Holger Fröhlich, Søren Jepsen, Andreas Jäger, Joni Augusto Cirelli, James Deschner

“…Eight of these genes could be confirmed by real-time PCR: NAMPT induced a significant upregulation of EGR1, MMP-1, SYT7, ITPKA, CCL2, NTM, IGF2BP3, and NRP1. NAMPT also increased significantly the MMP-1 and CCL2 protein synthesis. …”
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Electronic and thermal properties of Nb2CCl2 MXenes by H. Pazniak, T. Ouisse, U. Wiedwald, J. Gonzalez-Julian, T. Ito, F. Wilhelm, A. Rogalev, S. Quessada

“…In this work, we synthesize Nb2CCl2 MXenes by etching the Al layer from the Nb2AlC precursor in the melt of CuCl2 Lewis acid. …”
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<i>CCL2</i>, <i>CCR2</i> Gene Variants and CCL2, CCR2 Serum Levels Association with Age-Related Macular Degeneration by Gaile Gudauskiene, Alvita Vilkeviciute, Greta Gedvilaite, Rasa Liutkeviciene, Dalia Zaliuniene

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CCL2 Serum Levels and Adiposity Are Associated with the Polymorphic Phenotypes -2518A on CCL2 and 64ILE on CCR2 in a Mexican Population with Insulin Resistance by Milton-Omar Guzmán-Ornelas, Marcelo Heron Petri, Mónica Vázquez-Del Mercado, Efraín Chavarría-Ávila, Fernanda-Isadora Corona-Meraz, Sandra-Luz Ruíz-Quezada, Perla-Monserrat Madrigal-Ruíz, Jorge Castro-Albarrán, Flavio Sandoval-García, Rosa-Elena Navarro-Hernández

“…The aim of the study is to investigate the relationship between these polymorphisms with soluble CCL2 levels (sCCL2), metabolic markers, and adiposity. …”
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Predictive value of CCL2 in the prognosis and immunotherapy response of glioblastoma multiforme by Longfei Deng, Jie Ren, Benqin Li, Yinggang Wang, Nianfen Jiang, Yi Wang, Hongjuan Cui

“…Functional enrichment analysis revealed that CCL2 mainly participated in the regulation of chemokine signaling pathway and inflammatory response. …”
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CCL2: An important cytokine in normal and pathological pregnancies: A review by Zhi Lin, Zhi Lin, Jia-Lu Shi, Min Chen, Zi-Meng Zheng, Ming-Qing Li, Ming-Qing Li, Ming-Qing Li, Ming-Qing Li, Jun Shao, Jun Shao

Subjects: “…CCL2…”
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CCL2 responses to Mycobacterium tuberculosis are associated with disease severity in tuberculosis. by Zahra Hasan, Jacqueline M Cliff, Hazel M Dockrell, Bushra Jamil, Muhammad Irfan, Mussarat Ashraf, Rabia Hussain

“…M. tuberculosis-induced CCL2 mRNA transcription was greater in PTB than L-ETB (p = 0.023), while CCL2 was reduced in L-ETB as compared with D-ETB (p = 0.005) patients. …”
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Elucidating the Molecular Interactions of Chemokine CCL2 Orthologs with Flavonoid Baicalin by Nidhi Joshi, Dinesh Kumar, Krishna Mohan Poluri

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Anti-CCL2 therapy reduces oxygen toxicity to the immature lung by Tayyab Shahzad, Ying Dong, Nina K. Behnke, Julia Brandner, Anne Hilgendorff, Cho-Ming Chao, Judith Behnke, Saverio Bellusci, Harald Ehrhardt

“…To study the benefit of a targeted approach to prevent the pulmonary influx of macrophages, wildtype mice were repeatedly treated with CCL-2 blocking antibodies while exposed to hyperoxia for 7 days. …”
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Targeting CCL2-CCR2 Signaling Axis in Cancer Therapy by LU Xiaomei, FU Jiejun

Subjects: “…ccl2…”
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CCR2 acts as scavenger for CCL2 during monocyte chemotaxis. by Silvia Volpe, Elisabetta Cameroni, Barbara Moepps, Sylvia Thelen, Tiziana Apuzzo, Marcus Thelen

“…During chemotaxis CCL2-mCherry becomes endocytosed as cargo of CCR2, however, the internalization of CCR2 is not accompanied by reduced responsiveness of the cells due to desensitization. …”
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Targeting the CCL2-CCR2 signaling axis in cancer metastasis. by Lim, S, Yuzhalin, A, Gordon-Weeks, A, Muschel, R

“…The CCL2-CCR2 signaling axis has generated increasing interest in recent years due to its association with the progression of cancer. …”

CCL2 is a Potent Regulator of Prostate Cancer Cell Migration and Proliferation by Robert D. Loberg, LaShon L. Day, Jason Harwood, Chi Ying, Lauren N. St. John, Ryan Giles, Chris K. Neeley, Kenneth J. Pienta

Subjects: “…CCL2…”
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Noninvasive prediction of CCL2 expression level in high‐grade glioma patients by Qingqing Zhou, Yamei Wang, Qing Zhang, XiaoMing Wei, Yuan Yao, Liang Xia

Subjects: “…CCL2 expression level…”
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Microglia-derived CCL2 has a prime role in neocortex neuroinflammation by Mariella Errede, Tiziana Annese, Valentina Petrosino, Giovanna Longo, Francesco Girolamo, Ignazio de Trizio, Antonio d’Amati, Antonio Uccelli, Nicole Kerlero de Rosbo, Daniela Virgintino

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Aqueous Macrophages Contribute to Conserved CCL2 and CXCL10 Gradients in Uveitis by Joseph B. Lin, Kathryn L. Pepple, MD, PhD, Christian Concepcion, Yulia Korshunova, PhD, Michael A. Paley, MD, PhD, Grace L. Paley, MD, PhD, Jennifer Laurent, Rajendra S. Apte, MD, PhD, Lynn M. Hassman, MD, PhD

“…These data suggest that CCL2 and CXCL10 are key mediators in immune cell migration to the eye during uveitis. …”
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