Caregiver knowledge on chronic obstructive pulmonary disease (COPD) among COPD patient in outpatient clinic, Hospital Universiti Sains Malaysia by Mazlan, Nurul Farhana

“…For enabling the patients to improve their condition, caregivers need to be knowledgeable in facing patients with COPD. The general objective of the study was to determine caregiver knowledge on COPD among COPD patients in outpatient clinic Hospital USM. …”
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Residential exposure to Aspergillus spp. is associated with exacerbations in COPD by Tiew, Pei Yee, Leung, Janice M., Mac Aogáin, Micheál, Johal, Parteek, Jaggi, Tavleen Kaur, Yuen, Agnes Che Yan, Ivan, Fransiskus Xaverius, Yang, Julia, Afshar, Tina, Tee, Augustine, Koh, Mariko Siyue, Lim, Yee Hui, Wong, Anthony, Chandrasekaran, Lakshmi, Dacanay, Justine, Drautz-Moses, Daniela Isabel, Ong, Thun How, Abisheganaden, John Arputhan, Chew, Fook Tim, Schuster, Stephan Christoph, Carlsten, Christopher, Chotirmall, Sanjay Haresh

“…Background: Sensitisation to Aspergillus fumigatus is linked to worse outcomes in patients with COPD; however, its prevalence and clinical implications in domestic (residential) settings remains unknown. …”
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The relationship of dietary patterns with adult lung function and COPD. by Shaheen, S, Jameson, K, Syddall, H, Aihie Sayer, A, Dennison, E, Cooper, C, Robinson, S

“…A "prudent" dietary pattern may protect against impaired lung function and COPD, especially in male smokers.…”

Neutrophil elastase as a biomarker for bacterial infection in COPD by Thulborn, S, Mistry, V, Brightling, C, Moffitt, K, Ribeiro, D, Bafadhel, M

“…BACKGROUND: Chronic obstructive pulmonary disease (COPD) is predominantly associated with neutrophilic inflammation. …”

Computational modeling of the obstructive lung diseases asthma and COPD by Burrowes, K, Doel, T, Brightling, C

Blood Eosinophils and outcomes in severe hospitalized exacerbations of COPD by Bafadhel, M, Greening, NJ, Harvey-Dunstan, TC, Williams, JE, Morgan, MD, Brightling, CE, Hussain, SF, Pavord, ID, Singh, SJ, Steiner, MC

“…Background Patients with moderate exacerbations of COPD and the eosinophilic phenotype have better outcomes with prednisolone. …”

COPD can mimic the appearance of pneumothorax on thoracic ultrasound. by Slater, A, Goodwin, M, Anderson, K, Gleeson, F

“… PURPOSES: To determine the diagnostic accuracy of ultrasound in the diagnosis of pneumothorax in patients with COPD with particular regard to false-positive diagnoses. …”

Breathlessness in COPD: linking symptom clusters with brain activity by Finnegan, S, Harrison, O, Harmer, C, Herigstad, M, Rahman, N, Reinecke, A, Pattinson, K

“…<br><strong>Conclusions:</strong> This is the largest functional neuroimaging study of COPD to date and is the first to provide a clear model linking brain, behaviour and breathlessness expectation. …”

Is it time to give up on "self-management" of COPD exacerbations? by Ramakrishnan, S, Bafadhel, M

Type 2 diabetes: a protective factor for COPD? by Rayner, L, McGovern, A, Sherlock, J, Gatenby, P, Correa, A, Creagh-Brown, B, De Lusignan, S

“…<p><strong>BACKGROUND:</strong> Chronic obstructive pulmonary disease (COPD) and type 2 diabetes (T2DM) are common comorbidities. …”

Risk factors for severe COPD exacerbation in Chinese adults by Yu, W, Lan, Y, Sun, D, Pei, P, Yang, L, Chen, Y, Du, H, Peng, Y, Yang, X, Chen, J, Chen, Z, Lv, J, Li, L, Yu, C

“…Severe exacerbation is the predominant cause of COPD hospitalisation. We investigated sex-specific risk factors of severe exacerbation and explored the potential interactions of regions, smoking status, and age. …”

Disease severity of asthma/copd and risk of osteoporotic fractures by de Vries, F, van Staa, T, Bracke, M, Lammers, J, Cooper, C, Leufkens, H

Aspergillus fumigatus during stable state and exacerbations of COPD. by Bafadhel, M, McKenna, S, Agbetile, J, Fairs, A, Desai, D, Mistry, V, Morley, J, Pancholi, M, Pavord, I, Wardlaw, A, Pashley, C, Brightling, C

“…We investigated the frequency of filamentous fungal culture and IgE sensitisation to Aspergillus fumigatus and the relationship to clinical outcomes in COPD subjects. COPD subjects were recruited to enter a 1-year observational study. …”

Automatic generation of personalised alert thresholds for patients with COPD by Velardo, C, Shah, SA, Gibson, O, Rutter, H, Farmer, A, Tarassenko, L

“…Chronic Obstructive Pulmonary Disease (COPD) is a chronic disease predicted to become the third leading cause of death by 2030. …”

Blood eosinophil count and exacerbation risk in patients with COPD. by Kerkhof, M, Sonnappa, S, Postma, D, Brusselle, G, Agustí, A, Anzueto, A, Jones, R, Papi, A, Pavord, I, Pizzichini, E, Popov, T, Roche, N, Ryan, D, Thomas, M, Vogelmeier, C, Chisholm, A, Freeman, D, Bafadhel, M, Hillyer, E, Price, D

“…<p>Blood eosinophil counts are a promising biomarker to guide therapy for chronic obstructive pulmonary disease (COPD). We examined the association between blood eosinophil counts in stable COPD and exacerbations in the following year in real-life patients, and assessed whether the relationship differs in specific patient subgroups.…”

Investigating blood eosinophil count thresholds in patients with COPD by Russell, R, Bafadhel, M

"High-risk" clinical and inflammatory clusters in COPD of Chinese descent by Tiew, Pei Yee, Ko, Fanny Wai San, Narayana, Jayanth Kumar, Poh, Mau Ern, Xu, Huiying, Neo, Han Yee, Loh, Li-Cher, Ong, Choo Khoon, Mac Aogáin, Micheál, Tan, Jessica Han Ying, Kamaruddin, Nabilah Husna, Sim, Gerald Jiong Hui, Lapperre, Therese S., Koh, Mariko Siyue, Hui, David Shu Cheong, Abisheganaden, John Arputhan, Tee, Augustine, Tsaneva-Atanasova, Krasimira, Chotirmall, Sanjay Haresh

“…COPD is a heterogeneous disease demonstrating inter-individual variation. …”
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Sensitisation to recombinant Aspergillus fumigatus allergens and clinical outcomes in COPD by Tiew, Pei Yee, Narayana, Jayanth Kumar, Quek, Marilynn Swee Li, Ang, Yan Ying, Ko, Fanny Wai San, Poh, Mau Ern, Jaggi, Tavleen Kaur, Xu, Huiying, Thng, Kai Xian, Koh, Mariko Siyue, Tee, Augustine, Hui, David Shu Cheong, Abisheganaden, John Arputhan, Tsaneva-Atanasova, Krasimira, Chew, Fook Tim, Chotirmall, Sanjay Haresh

“…Background Variable clinical outcomes are reported with fungal sensitisation in chronic obstructive pulmonary disease (COPD), and it remains unclear which fungi and what allergens associate with the poorest outcomes. …”
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The role of acute and chronic respiratory colonization and infections in the pathogenesis of COPD by Leung, Janice M., Tiew, Pei Yee, Mac Aogáin, Micheál, Budden, Kurtis F., Yong, Valerie Fei Lee, Thomas, Sangeeta Susan, Pethe, Kevin, Hansbro, Philip M., Chotirmall, Sanjay Haresh

“…COPD is a major global concern, increasingly so in the context of ageing populations. …”
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Digital health system for personalised COPD long-term management by Velardo, C, Shah, S, Gibson, O, Clifford, G, Heneghan, C, Rutter, H, Farmer, A, Tarassenko, L