Single-cell RNA sequencing identifies a population of human liver-type ILC1s by Benjamin Krämer, Ansel P. Nalin, Feiyang Ma, Sarah Eickhoff, Philipp Lutz, Sonia Leonardelli, Felix Goeser, Claudia Finnemann, Gudrun Hack, Jan Raabe, Michael ToVinh, Sarah Ahmad, Christoph Hoffmeister, Kim M. Kaiser, Steffen Manekeller, Vittorio Branchi, Tobias Bald, Michael Hölzel, Robert Hüneburg, Hans Dieter Nischalke, Alexander Semaan, Bettina Langhans, Dominik J. Kaczmarek, Brooke Benner, Matthew R. Lordo, Jesse Kowalski, Adam Gerhardt, Jörg Timm, Marieta Toma, Raphael Mohr, Andreas Türler, Arthur Charpentier, Tobias van Bremen, Georg Feldmann, Arne Sattler, Katja Kotsch, Ali T. Abdallah, Christian P. Strassburg, Ulrich Spengler, William E. Carson, III, Bethany L. Mundy-Bosse, Matteo Pellegrini, Timothy E. O’Sullivan, Aharon G. Freud, Jacob Nattermann

Subjects: “…CP: Immunology…”
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Vascular traffic control of neutrophil recruitment to the liver by microbiota-endothelium crosstalk by Amanda Z. Zucoloto, Jared Schlechte, Aline Ignacio, Carolyn A. Thomson, Shannon Pyke, Ian-ling Yu, Markus B. Geuking, Kathy D. McCoy, Bryan G. Yipp, Mark R. Gillrie, Braedon McDonald

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Liver sinusoidal endothelial cells orchestrate NK cell recruitment and activation in acute inflammatory liver injury by Sophia Papaioannou, Jia-Xiang See, Mingeum Jeong, Carolina De La Torre, Volker Ast, Philipp-Sebastian Reiners-Koch, Ankita Sati, Carolin Mogler, Michael Platten, Adelheid Cerwenka, Ana Stojanovic

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Chronic viral infection alters PD-1 locus subnuclear localization in cytotoxic CD8+ T cells by Catarina Sacristán, Ben A. Youngblood, Peiyuan Lu, Alexander P.R. Bally, Jean Xiaojin Xu, Katelyn McGary, Susannah L. Hewitt, Jeremy M. Boss, Jane A. Skok, Rafi Ahmed, Michael L. Dustin

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IL-22 promotes mucin-type O-glycosylation and MATH1+ cell-mediated amelioration of intestinal inflammation by Ankita Singh, Michael Beaupre, Cecilia Villegas-Novoa, Kiyoshi Shiomitsu, Stephen J. Gaudino, Suzanne Tawch, Ruhee Damle, Cody Kempen, Biswa Choudhury, Jeremy P. McAleer, Brian S. Sheridan, Paula Denoya, Richard S. Blumberg, Patrick Hearing, Nancy L. Allbritton, Pawan Kumar

Subjects: “…CP: Immunology…”
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Bcl6 is a subset-defining transcription factor of lymphoid tissue inducer-like ILC3 by Roser Tachó-Piñot, Christopher T. Stamper, James I. King, Veronika Matei-Rascu, Erin Richardson, Zhi Li, Luke B. Roberts, John W. Bassett, Felipe Melo-Gonzalez, Rémi Fiancette, I-Hsuan Lin, Alexander Dent, Yohsuke Harada, Conor Finlay, Jenny Mjösberg, David R. Withers, Matthew R. Hepworth

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A genetic method specifically delineates Th1-type Treg cells and their roles in tumor immunity by Masaaki Okamoto, Miwa Sasai, Ayumi Kuratani, Daisuke Okuzaki, Masaya Arai, James B. Wing, Shimon Sakaguchi, Masahiro Yamamoto

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Defective peripheral B cell selection in common variable immune deficiency patients with autoimmune manifestations by Vanda Friman, Isabella Quinti, Alexey N. Davydov, Mikhail Shugay, Chiara Farroni, Erik Engström, Shirin Pour Akaber, Sabina Barresi, Ahmed Mohamed, Federica Pulvirenti, Cinzia Milito, Guido Granata, Ezio Giorda, Sara Ahlström, Johanna Karlsson, Emiliano Marasco, Valentina Marcellini, Chiara Bocci, Simona Cascioli, Marco Scarsella, Ganesh Phad, Andreas Tilevik, Marco Tartaglia, Mats Bemark, Dmitriy M. Chudakov, Rita Carsetti, Ola Grimsholm

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Early precursor-derived pituitary gland tissue-resident macrophages play a pivotal role in modulating hormonal balance by Henna Lehtonen, Heli Jokela, Julian Hofmann, Lauriina Tola, Arfa Mehmood, Florent Ginhoux, Burkhard Becher, Melanie Greter, Gennady G. Yegutkin, Marko Salmi, Heidi Gerke, Pia Rantakari

Subjects: “…CP: Immunology…”
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Mixed IgG Fc immune complexes exhibit blended binding profiles and refine FcR affinity estimates by Zhixin Cyrillus Tan, Anja Lux, Markus Biburger, Prabha Varghese, Stephen Lees, Falk Nimmerjahn, Aaron S. Meyer

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PSGL-1 attenuates early TCR signaling to suppress CD8+ T cell progenitor differentiation and elicit terminal CD8+ T cell exhaustion by Jennifer L. Hope, Dennis C. Otero, Eun-Ah Bae, Christopher J. Stairiker, Ashley B. Palete, Hannah A. Faso, Michelle Lin, Monique L. Henriquez, Sreeja Roy, Hyungseok Seo, Xue Lei, Eric S. Wang, Savio Chow, Roberto Tinoco, Gregory A. Daniels, Kevin Yip, Alexandre Rosa Campos, Jun Yin, Peter D. Adams, Anjana Rao, Linda M. Bradley

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Small-molecule screening identifies Syk kinase inhibition and rutaecarpine as modulators of macrophage training and SARS-CoV-2 infection by Sinu P. John, Anju Singh, Jing Sun, Makheni Jean Pierre, Lulwah Alsalih, Crystal Lipsey, Ziann Traore, Shenavia Balcom-Luker, Clinton J. Bradfield, Jian Song, Tovah E. Markowitz, Margery Smelkinson, Marc Ferrer, Iain D.C. Fraser

Subjects: “…CP: Immunology…”
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Tracking B cell responses to the SARS-CoV-2 mRNA-1273 vaccine by Felipe Lopes de Assis, Kenneth B. Hoehn, Xiaozhen Zhang, Lela Kardava, Connor D. Smith, Omar El Merhebi, Clarisa M. Buckner, Krittin Trihemasava, Wei Wang, Catherine A. Seamon, Vicky Chen, Paul Schaughency, Foo Cheung, Andrew J. Martins, Chi-I Chiang, Yuxing Li, John S. Tsang, Tae-Wook Chun, Steven H. Kleinstein, Susan Moir

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CD226 maintains regulatory T cell phenotype stability and metabolism by the mTOR/Myc pathway under inflammatory conditions by Jingchang Ma, Wei Hu, Yitian Liu, Chujun Duan, Dongliang Zhang, Yuling Wang, Kun Cheng, Lu Yang, Shuwen Wu, Boquan Jin, Yuan Zhang, Ran Zhuang

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Identification of a broad sarbecovirus neutralizing antibody targeting a conserved epitope on the receptor-binding domain by Yanqun Wang, Zhaoyong Zhang, Minnan Yang, Xinyi Xiong, Qihong Yan, Lei Cao, Peilan Wei, Yuting Zhang, Lu Zhang, Kexin Lv, Jiantao Chen, Xuesong Liu, Xiaochu Zhao, Juxue Xiao, Shengnan Zhang, Airu Zhu, Mian Gan, Jingjun Zhang, Ruoxi Cai, Jianfen Zhuo, Yanjun Zhang, Haiyue Rao, Bin Qu, Yuanyuan Zhang, Lei Chen, Jun Dai, Linling Cheng, Qingtao Hu, Yaoqing Chen, Huibin Lv, Ray T.Y. So, Malik Peiris, Jingxian Zhao, Xiaoqing Liu, Chris Ka Pun Mok, Xiangxi Wang, Jincun Zhao

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Unveiling IRF4-steered regulation of context-dependent effector programs in CD4+ T cells under Th17- and Treg-skewing conditions by Anna Gabele, Maximilian Sprang, Mert Cihan, Mareen Welzel, Assel Nurbekova, Karolina Romaniuk, Sarah Dietzen, Matthias Klein, Georg Bündgen, Maxim Emelianov, Gregory Harms, Krishnaraj Rajalingam, Tanja Ziesmann, Katrin Pape, Beatrice Wasser, David Gomez-Zepeda, Kathrin Braband, Michael Delacher, Niels Lemmermann, Stefan Bittner, Miguel A. Andrade-Navarro, Stefan Tenzer, Katja Luck, Tobias Bopp, Ute Distler

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Human papillomavirus E5 suppresses immunity via inhibition of the immunoproteasome and STING pathway by Sayuri Miyauchi, Sangwoo S. Kim, Riley N. Jones, Lin Zhang, Kripa Guram, Sonia Sharma, Stephen P. Schoenberger, Ezra E.W. Cohen, Joseph A. Califano, Andrew B. Sharabi

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Lack of functional TCR-epitope interaction is associated with herpes zoster through reduced downstream T cell activation by Marlies Boeren, Nicky de Vrij, My K. Ha, Sebastiaan Valkiers, Aisha Souquette, Sofie Gielis, Mariia Kuznetsova, Jolien Schippers, Esther Bartholomeus, Johan Van den Bergh, Nele Michels, Olivier Aerts, Julie Leysen, An Bervoets, Julien Lambert, Elke Leuridan, Johan Wens, Karin Peeters, Marie-Paule Emonds, George Elias, Niels Vandamme, Hilde Jansens, Wim Adriaensen, Arvid Suls, Stijn Vanhee, Niel Hens, Evelien Smits, Pierre Van Damme, Paul G. Thomas, Philippe Beutels, Peter Ponsaerts, Viggo Van Tendeloo, Peter Delputte, Kris Laukens, Pieter Meysman, Benson Ogunjimi

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Targeting RSV-neutralizing B cell receptors with anti-idiotypic antibodies by Samuel C. Scharffenberger, Yu-Hsin Wan, Leah J. Homad, Gargi Kher, Austin M. Haynes, Bibhav Poudel, Irika R. Sinha, Nicholas Aldridge, Ayana Pai, Madeleine Bibby, Crystal B. Chhan, Amelia R. Davis, Zoe Moodie, Maria Belen Palacio, Amelia Escolano, M. Juliana McElrath, Jim Boonyaratanakornkit, Marie Pancera, Andrew T. McGuire

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The changing health impact of vaccines in the COVID-19 pandemic: A modeling study by Jamie A. Cohen, Robyn M. Stuart, Jasmina Panovska-Griffiths, Edinah Mudimu, Romesh G. Abeysuriya, Cliff C. Kerr, Michael Famulare, Daniel J. Klein

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