Association of CYP2E1 polymorphisms with gastrointestinal cancer in Malaysia by Chong, Eric Tzvy Jiann

“…Malaysia has a high mortality rate of gastrointestinal cancer (GIC) and hence finding a biomarker for GIC is crucial. CYP2E1 polymorphisms have been associated to increase the risk of GIC in many populations but remain unclear in Malaysian. …”
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Mouse spermatocytes express CYP2E1 and respond to acrylamide exposure. by Belinda J Nixon, Aimee L Katen, Simone J Stanger, John E Schjenken, Brett Nixon, Shaun D Roman

“…Thus, to investigate the mechanisms of acrylamide toxicity in mouse male germ cells, we examined the expression of the CYP, CYP2E1, which metabolises acrylamide. Using Q-PCR and immunohistochemistry, we establish that CYP2E1 is expressed in germ cells, in particular in spermatocytes. …”
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Contribution of CYP2E1 polymorphism to aging in the mechanical workshop workers by Eshkoor, Sima Ataollahi, Ismail, Patimah, Abdul Rahman, Sabariah, Adon, Mohd Yusoff, Vasudevan, Ramachandran

“…Cytochrome P450 2E1 (CYP2E1) gene contributes in activation and detoxification of the environmental hazards. …”

Induction of Cyp2e1 contributes to asparaginase-induced hepatocyte sensitization to lipotoxicity by Yin Zhu, Yuyin Wang, Keito Hoshitsuki, Da Yang, Lauren Kokai, Xiaochao Ma, Wen Xie, Christian A. Fernandez

“…Mechanistically, our RNA-sequencing (RNA-seq) analyses reveal that PEG-ASNase-induced sensitization to lipotoxicity is accompanied by the induction of Cyp2e1. We demonstrated that this sensitization effect is attenuated by both pharmacological and genetic inhibition of Cyp2e1. …”
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Fisetin Attenuates Paracetamol-Induced Hepatotoxicity by Regulating CYP2E1 Enzyme by RUSTEM A. UGAN, ELIF CADIRCI, HARUN UN, IRFAN CINAR, MUHAMMET A. GURBUZ

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Fasting Enhances the Acute Toxicity of Acrylonitrile in Mice via Induction of CYP2E1 by Suhua Wang, Guangwei Xing, Fang Li, Bobo Yang, Yu Zhang, Michael Aschner, Rongzhu Lu

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Cytochrome P450 CYP2E1 Suppression Ameliorates Cerebral Ischemia Reperfusion Injury by Jin Yu, Hong Zhu, Mark S. Kindy, Saeid Taheri

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Association of mitochondrial deoxyribonucleic acid mutation with polymorphism in CYP2E1 gene in oral carcinogenesis by Rahul Pandey, Divya Mehrotra, Carlo Catapano, Vimal Choubey, Rajiv Sarin, Abbas Ali Mahdi, Stuti Singh

Subjects: “…CYP2E1…”
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A Novel Cytochrome P450 2E1 Inhibitor Q11 Is Effective on Lung Cancer via Regulation of the Inflammatory Microenvironment by Lin Jia, Fei Gao, Guiming Hu, Yan Fang, Liming Tang, Qiang Wen, Na Gao, Haiwei Xu, Hailing Qiao

Subjects: “…CYP2E1…”
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Genetic variations in the drug metabolizing enzyme, CYP2E1, among various ethnic populations of Pakistan by Sagheer Ahmed, Nadeem Altaf, Mahnoor Ejaz, Zaira Zulfiqar, Kholood Janjua, Dana Festila, Nicula Cristina

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NF-κB-mediated regulation of rat CYP2E1 by two independent signaling pathways. by Qin Lin, Xiaolin Kang, Xuefeng Li, Tao Wang, Fengting Liu, Jinxue Jia, Ziqi Jin, Yongzhi Xue

“…Cytochrome P450 2E1 (CYP2E1) plays an important role in both alcohol-induced and immune-mediated liver injury. …”
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Chlorzoxazone reduced the paracetamol-induced toxicity via competitive inhibition of CYP2E1-mediated metabolism by Ravindra Babu Pingili, Sridhar Vemulapalli, Manideep V. V. N. Gadamsetty, Divya Presingu, Ruthvik Katuri, Vijayalakshmi Rachamsetty, Naveen Babu Kilaru

Subjects: “…CYP2E1…”
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CYP2E1 deficit mediates cholic acid-induced malignant growth in hepatocellular carcinoma cells by Zhiwei Hao, Xuemin Liu, Huanhuan He, Zhixuan Wei, Xiji Shu, Jianzhi Wang, Binlian Sun, Hongyan Zhou, Jiucheng Wang, Ying Niu, Zhiyong Hu, Shaobo Hu, Yuchen Liu, Zhengqi Fu

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Bielectrode Strategy for Determination of CYP2E1 Catalytic Activity: Electrodes with Bactosomes and Voltammetric Determination of 6-Hydroxychlorzoxazone by Alexey V. Kuzikov, Rami A. Masamrekh, Tatiana A. Filippova, Anastasiya M. Tumilovich, Natallia V. Strushkevich, Andrei A. Gilep, Yulia Yu. Khudoklinova, Victoria V. Shumyantseva

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The Physiological Mechanism of Improved Formaldehyde Resistance in Petunia hybrida Harboring a Mammalian cyp2e1 Gene by Wang Man, Xiang Taihe, Song Yaling, Huang Yingying, Han Yixuan, Sun Yang

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Amelioration of ethanol-induced oxidative stress and alcoholic liver disease by in vivo RNAi targeting Cyp2e1 by Yalan Wang, Qiubing Chen, Shuang Wu, Xinyu Sun, Runting Yin, Zhen Ouyang, Hao Yin, Yuan Wei

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Subcellular expression of CYP2E1 in HepG2 cells impacts response to free oleic and palmitic acid by Zaria K. Killingsworth, Kelly R. Misare, Abigail S. Ryan, Elizabeth A. Ampolini, Tsultrim T. Mendenhall, Melinda A. Engevik, Jessica H. Hartman

Subjects: “…CYP2E1…”
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Genetic polymorphisms in FABP2, CYP2E1, and TP53 genes are potentially associated with colorectal cancer susceptibility by Maryam Ijaz, Chien-Chin Chen, Rana Khalid Iqbal, Hafiza Aneela Farooq, Rubaida Mehmood, Muhammad Asif, Atif Akbar, Adil Khan, Waseem Ijaz, Mourad Ben Said, Gezahign Fentahun Wondmie, Samir Ibenmoussa, Mohammad K. Okla, Furhan Iqbal

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Silymarin Protects against Acute Liver Injury Induced by Acetaminophen by Downregulating the Expression and Activity of the CYP2E1 Enzyme by Weipei Yang, Zhongxu Liang, Chengming Wen, Xuehua Jiang, Ling Wang

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Association of NOTCH4 and CYP2E1 Genetic Variants With Schizophrenia in the Bangladeshi Population: A Case‐Control Study by Md. Shalahuddin Millat, Joysree Roy, Md. Atikur Rahman, Md. Abdul Aziz, Safiqul Islam, Md. Mazharul Islam Chowdhury, Md Abdul Barek, Md. Saddam Hussain, Mohammad Sarowar Uddin, Shafayet Ahmed Siddiqui, Mohammad Safiqul Islam

Subjects: “…CYP2E1…”
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