Semi-supervised Learning Predicts Approximately One Third of the Alternative Splicing Isoforms as Functional Proteins by Yanqi Hao, Recep Colak, Joan Teyra, Carles Corbi-Verge, Alexander Ignatchenko, Hannes Hahne, Mathias Wilhelm, Bernhard Kuster, Pascal Braun, Daisuke Kaida, Thomas Kislinger, Philip M. Kim

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Adenylyl cyclase isoforms 5 and 6 in the cardiovascular system: complex regulation and divergent roles by Saeid Maghsoudi, Saeid Maghsoudi, Rabia Shuaib, Ben Van Bastelaere, Shyamala Dakshinamurti, Shyamala Dakshinamurti, Shyamala Dakshinamurti

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HCK and ABAA: A Newly Designed Pipeline to Improve Fungi Metabarcoding Analysis by Kodjovi D. Mlaga, Alban Mathieu, Alban Mathieu, Charles Joly Beauparlant, Charles Joly Beauparlant, Alban Ott, Ahmad Khodr, Olivier Perin, Arnaud Droit, Arnaud Droit

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“Smart” Matrix Microneedle Patch Made of Self‐Crosslinkable and Multifunctional Polymers for Delivering Insulin On‐Demand by Jackie Fule Liu, Amin GhavamiNejad, Brian Lu, Sako Mirzaie, Melisa Samarikhalaj, Adria Giacca, Xiao Yu Wu

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Methodologic attributes of quality improvement studies in neonatology: a systematic survey by Lehana Thabane, Zheng Jing Hu, Salhab el Helou, Gerhard Fusch, Catherine Hu, Jie Yi Wang, Maleeka Munroe

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Memory Deficits for Health Information Provided Through a Telehealth Video Conferencing System by Benjamin Rich Zendel, Benjamin Rich Zendel, Bethany Victoria Power, Roberta Maria DiDonato, Roberta Maria DiDonato, Veronica Margaret Moore Hutchings, Veronica Margaret Moore Hutchings

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Microbiology in the Field: Construction and Validation of a Portable Incubator for Real-Time Quantification of Coliforms and Other Bacteria by Jordan Wight, Marie-Pierre Varin, Gregory J. Robertson, Yannick Huot, Andrew S. Lang

“…We developed and constructed rugged, reliable, and cost-effective portable incubators that were used by 10 independent field teams to perform microbiological assays on surface water samples from lakes across Canada. Rigorous testing and validation of our incubators ensured that incubation conditions were consistent within and across all 10 field teams and 2 sampling years. …”
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Risk of contralateral lower limb amputation and death after initial lower limb amputation – a population-based study by K. Huseynova, R. Sutradhar, G.L. Booth, A. Huang, J.G. Ray

“…This is a retrospective population-based cohort study across Ontario, Canada, 2002–2012. Cause-specific Cox regression models were used to obtain hazard ratios. …”
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Impact of Sample Storage Time and Temperature on the Stability of Respiratory Viruses and Enteric Viruses in Wastewater by Judy Y. Qiu, Richardson Mah, Logan A. Brand, Xiaoli Pang, Melodie Barnett, Mathew Diggle, Graham Tipples

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An engineered transcription factor which activates VEGF-A enhances recovery after spinal cord injury by Yang Liu, Sarah Figley, S. Kaye Spratt, Gary Lee, Dale Ando, Richard Surosky, Michael G. Fehlings

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Female-biased upregulation of insulin pathway activity mediates the sex difference in Drosophila body size plasticity by Jason W Millington, George P Brownrigg, Charlotte Chao, Ziwei Sun, Paige J Basner-Collins, Lianna W Wat, Bruno Hudry, Irene Miguel-Aliaga, Elizabeth J Rideout

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Innate Recognition of Intracellular Bacterial Growth Is Driven by the TIFA-Dependent Cytosolic Surveillance Pathway by Ryan G. Gaudet, Cynthia X. Guo, Raphael Molinaro, Haila Kottwitz, John R. Rohde, Anne-Sophie Dangeard, Cécile Arrieumerlou, Stephen E. Girardin, Scott D. Gray-Owen

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What Are the Modulators of Cross-Language Syntactic Activation During Natural Reading? by Naomi Vingron, Pauline Palma, Jason W. Gullifer, Veronica Whitford, Deanna Friesen, Debra Jared, Debra Titone

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Longevity Extension by Phytochemicals by Anna Leonov, Anthony Arlia-Ciommo, Amanda Piano, Veronika Svistkova, Vicky Lutchman, Younes Medkour, Vladimir I. Titorenko

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Performance of a Three-Tier (IRT-DNA-IRT) Cystic Fibrosis Screening Algorithm in British Columbia by Graham Sinclair, Vanessa McMahon, Amy Schellenberg, Tanya N. Nelson, Mark Chilvers, Hilary Vallance

“…The British Columbia (BC) newborn screening program tests ~45,000 infants per year in BC and the Yukon Territory, covering almost 1.5 million km² in western Canada. CF screening was initiated using an IRT-DNA-IRT approach with a second bloodspot card at 21 days of age for all CFTR mutation heterozygotes and any non-carriers in the top 0.1% for IRT. …”
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TILE pilot trial study protocol: Tinzaparin Lead-in to Prevent the Post-Thrombotic syndrome study protocol by Sam Schulman, Aurélien Delluc, Jameel Abdulrehman, Susan Kahn, Jean-Philippe Galanaud, Ilia Makedonov, Peter L Gross

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Particulate contamination of human placenta: Plastic and non-plastic by Rewa E. Zurub, Shannon Bainbridge, Luna Rahman, Sabina Halappanavar, Darine El-Chaâr, Michael G. Wade

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The association between parents' stress and parental feeding practices and feeding styles: Systematic review and meta‐analysis of observational studies by Dina Almaatani, Andreea Zurbau, Farnaz Khoshnevisan, Robert H. J. Bandsma, Tauseef A. Khan, John L. Sievenpiper, Meta Van Den Heuvel

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HPV16 Intratypic Variants in Head and Neck Cancers: A North American Perspective by Steven F. Gameiro, Mikhail Y. Salnikov, Peter Y. F. Zeng, John W. Barrett, Anthony C. Nichols, Joe S. Mymryk

“…We combined HPV16 positive (HPV16⁺) HNC samples from a local Southwestern Ontario, Canada cohort with those from the Cancer Genome Atlas to create a larger North American cohort of 149 cases with clinical data and determined the distribution of intratypic variants and their impact on clinical outcomes. …”
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De novo genetic variation revealed in somatic sectors of single Arabidopsis plants [v1; ref status: indexed, http://f1000r.es/kw] by Marianne T Hopkins, Aaron M Khalid, Pei-Chun Chang, Karen C Vanderhoek, Dulcie Lai, Meghan D Doerr, Susan J Lolle

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