Barriers and facilitators to COVID-19 vaccine acceptability among people incarcerated in Canadian federal prisons: A qualitative study by David Lessard, David Ortiz-Paredes, Hyejin Park, Olivia Varsaneux, James Worthington, Nicole E. Basta, Shannon E. MacDonald, Bertrand Lebouché, Joseph Cox, Shainoor J. Ismail, Nadine Kronfli

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Delineating and Operationalizing the Definition of Patient-Oriented Research: A Modified e-Delphi Study by Navdeep Kaur, Pierre Pluye

“…The current Canadian Institutes of Health Research (CIHR) definition of POR is overly broad and hinders the reliable selection of POR-related publications from bibliographic databases. …”
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Recruitment of multiple stakeholders to health services research: Lessons from the front lines by Brouwers Melissa C, Makarski Julie, Rawski Ellen, Kho Michelle E

“…Here, we highlight the challenges of recruiting key stakeholders (policy-makers, clinicians, guideline developers) to a Canadian Institutes of Health Research (CIHR) funded health services research (HSR) study aimed to develop an updated and refined version of a guideline appraisal tool, the AGREE.…”
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ParticipACTION: Overview and introduction of baseline research on the "new" ParticipACTION by Craig Cora L, Tremblay Mark S

“…</p> <p>Results</p> <p>The research team was successful in obtaining funding through the new Canadian Institutes of Health Research Intervention Research (Healthy Living and Chronic Disease Prevention) Funding Program. …”
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“Media, politics and science policy: MS and evidence from the CCSVI Trenches” by Pullman Daryl, Zarzeczny Amy, Picard André

“…</p> <p>Discussion</p> <p>We present three different perspectives on this evolving story, that of a health journalist who played a key role in the media coverage of this issue, that of a health law and policy scholar who has closely observed the unfolding public policy developments across the country, and that of a medical ethicist who sits on an expert panel convened by the MS Society of Canada and the Canadian Institutes of Health Research to assess the evidence as it emerges.…”
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A qualitative study of Canadian resident experiences with Competency-Based Medical Education by Leora Branfield Day, Terry Colbourne, Alex Ng, Franco Rizzuti, Linda Zhou, Rani Mungroo, Allan McDougall

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Meeting the Challenge of the “Know-Do” Gap; Comment on “CIHR Health System Impact Fellows: Reflections on ‘Driving Change’ Within the Health System” by David J. Hunter

“…Initiatives like the Canadian Institutes of Health Research (CIHR) Health System Impact (HSI) Fellowship are therefore both timely and welcome. …”
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Adipose browning response to burn trauma is impaired with aging by Abdikarim Abdullahi, Carly M. Knuth, Christopher Auger, Thibacg Sivayoganathan, Alexandra Parousis, Marc G. Jeschke

“…Mechanistically, we found that the adipose of both aged patients after burn trauma and aged mice after a burn showed impairments in macrophage infiltration and IL-6, key immunological regulators of the browning process after a severe trauma.CONCLUSION Targeting pathways that activate the browning response represents a potential therapeutic approach to improve outcomes after burn trauma for elderly patients.FUNDING NIH (R01-GM087285-01), Canadian Institutes of Health Research (grant no. 123336), and Canada Foundation for Innovation Leaders Opportunity Fund (no. 25407).…”
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A Randomised Controlled Trial of Therapist-Assisted, Internet-Delivered Cognitive Behavior Therapy for Women with Maternal Depression. by Nicole E Pugh, Heather D Hadjistavropoulos, Dale Dirkse

“…This study was registered with the International Standard Randomized Controlled Trials (85456371) and received funding from Canadian Institutes of Health Research (#101526) and the Saskatchewan Health Research Foundation. …”
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Women’s decision-making needs related to treatment for recurrent ovarian cancer: A pilot study by Lynne J.A. Jolicoeur, Annette M. O'Connor, Laura Hopkins, Ian D. Graham

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Building the field of population health intervention research: The development and use of an initial set of competencies by Barbara Riley, Jean Harvey, Erica Di Ruggiero, Louise Potvin

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Reflections on patient engagement by patient partners: how it can go wrong by Dawn P. Richards, Sabrina Poirier, Vina Mohabir, Laurie Proulx, Sue Robins, Jeffery Smith

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mTORC1 Activates SREBP-1c and Uncouples Lipogenesis From Gluconeogenesis by Laplante, Mathieu, Sabatini, David

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Functional Clustering Drives Encoding Improvement in a Developing Brain Network during Awake Visual Learning by Dunfield, Derek, Podgorski, Kaspar, Haas, Kurt

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Barcoding bias in high-throughput multiplex sequencing of miRNA by Alon, Shahar, Vigneault, Francois, Eminaga, Seda, Christodoulou, Danos C., Seidman, Jonathan G., Church, George M., Eisenberg, Eli

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Clinician-scientists in Canada: barriers to career entry and progress. by Bryn Lander, Gillian E Hanley, Janet Atkinson-Grosjean

“…These perceptions were then compared against statistical analysis of data from Canadian Institutes of Health Research (CIHR) databases on grant and award performance of clinician-scientists and non-clinical PhDs for fiscal years 2000 to 2008. …”
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Sex and gender analysis in knowledge translation interventions: challenges and solutions by Amédé Gogovor, Tatyana Mollayeva, Nicole Etherington, Angela Colantonio, France Légaré, on behalf of the GIKT Group

“…In 2018, six research teams funded by the Canadian Institutes of Health Research’s Institute of Gender and Health met in Ottawa to discuss these challenges and solutions. …”
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Metronidazole treatment rapidly reduces genital inflammation through effects on bacterial vaginosis–associated bacteria rather than lactobacilli by Eric Armstrong, Anke Hemmerling, Steve Miller, Kerianne E. Burke, Sara J. Newmann, Sheldon R. Morris, Hilary Reno, Sanja Huibner, Maria Kulikova, Rachel Liu, Emily D. Crawford, Gloria R. Castañeda, Nico Nagelkerke, Bryan Coburn, Craig R. Cohen, Rupert Kaul

“…BV treatment induced no change in the absolute abundance of L. crispatus or L. iners and only minor (&lt;1 log10–fold) increases in L. gasseri and L. jensenii that were not independently associated with reduced inflammation in multivariable models.CONCLUSION The genital immune benefits that are associated with Lactobacillus dominance after BV treatment were not directly attributable to an absolute increase in lactobacilli, but rather to the loss of BV-associated bacteria.Trial REGISTRATION Participants were recruited as part of a randomized controlled trial (ClinicalTrials.gov NCT02766023) from 2016 to 2019.FUNDING Canadian Institutes of Health Research (PJT-156123) and the National Institute of Allergy and Infectious Diseases (HHSN2722013000141 and HHSN27200007).…”
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Building a Pan-Canadian Real World Health Data Network by Mark Smith, Michael Schull, Kimberlyn McGrail, Alan Katz, Brent Diverty, Ted McDonald, Charles Victor, Lisa Lix, Alison Paprica

“…Background In December 2017 the Canadian Institutes of Health Research (CIHR) issued a request for proposals to develop a pan-Canadian health data platform. …”
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Training in the implementation of sex and gender research policies: an evaluation of publicly available online courses by Annika Gompers, Madeline T. Olivier, Donna L. Maney

“…Methods Here, we evaluated three sets of publicly available online training materials on this topic: (1) Integrating Sex & Gender in Health Research from the Canadian Institutes of Health Research (CIHR); (2) Sex as a Biological Variable: A Primer from the United States National Institutes of Health (NIH); and (3) The Sex and Gender Dimension in Biomedical Research, developed as part of “Leading Innovative measures to reach gender Balance in Research Activities” (LIBRA) from the European Commission. …”
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