Colorectal cancer: prevention and early diagnosis by Stockenhuber, K, East, JE

“…Colorectal cancer (CRC) is one of the leading causes of cancer deaths worldwide. …”

Anti-cancer activity and mechanism of action of rice bran phytic acid on colon cancer in vitro and in vivo by Shafie, Nurul Husna

“…Colorectal cancer or colon cancer is a major neoplastic disease affecting men and women worldwide. …”
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Functional genetics of cancer and congenital disorders by Zak, J

“…This thesis aims to identify and assess pathogenic mutations in the 1q41q42 microdeletion syndrome, neural tube defects, neuropsychiatric disorders and cancer. Rare microdeletions at the 1q41q42 locus cause a clinically heterogeneous syndrome characterized by developmental delay, characteristic dysmorphic features and brain morphological abnormalities. …”

Regulatory roles of endothelial cells in cancer by Franses, Joseph W. (Joseph Wang)

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Mathematical modelling of metabolism and acidity in cancer by McGillen, J

“…<p>Human cancers exhibit the common phenotype of elevated glycolytic metabolism, which causes acidification of the tissue microenvironment and may facilitate tumour invasion. …”

Radon and cancers other than lung cancer in underground miners: a collaborative analysis of 11 studies. by Darby, S, Whitley, E, Howe, G, Hutchings, S, Kusiak, R, Lubin, J, Morrison, H, Tirmarche, M, Tomásek, L, Radford, E

“…This study, therefore, provides considerable evidence that high concentrations of radon in air do not cause a material risk of mortality from cancers other than lung cancer. …”

The evolving epidemic of breast cancer in sub-Saharan Africa. Results from the African Cancer Registry Network by Joko-Fru, WY, Jedy-Agba, E, Korir, A, Ogunbiyi, O, Dzamalala, CP, Chokunonga, E, Wabinga, H, Manraj, S, Finesse, A, Somdyala, N, Liu, B, McGale, P, Jemal, A, Bray, F, Parkin, DM

“…Breast cancer (BC) is the leading cause of cancer in sub-Saharan Africa (SSA) with rapidly increasing incidence rates reported in Uganda and Zimbabwe. …”

Meat and fish consumption and risk of pancreatic cancer: results from the European Prospective Investigation into Cancer and Nutrition. by Rohrmann, S, Linseisen, J, Nöthlings, U, Overvad, K, Egeberg, R, Tjønneland, A, Boutron-Ruault, M, Clavel-Chapelon, F, Cottet, V, Pala, V, Tumino, R, Palli, D, Panico, S, Vineis, P, Boeing, H, Pischon, T, Grote, V, Teucher, B, Khaw, K, Wareham, N, Crowe, F, Goufa, I, Orfanos, P, Trichopoulou, A, Jeurnink, S

“…Pancreatic cancer is the fourth most common cause of cancer death worldwide with large geographical variation, which implies the contribution of diet and lifestyle in its etiology. …”

Causes, consequences, and remedies for growth-induced solid stress in murine and human tumors by Martin, John Daniel, Jain, Saloni R., Stylianopoulosa, Triantafyllos, Chauhana, Vikash P., Bardeesy, Nabeel, Diop-Frimpong, Benjamin, Stylianopoulos, Triantafyllos, Smith, Barbara L., Ferrone, Cristina R., Hornicek, Francis J., Boucher, Yves, Munn, Lance L., Jain, Rakesh K.

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Causes of genome instability: the effect of low dose chemical exposures in modern society by Langie, Sabine A. S., Koppen, Gudrun, Desaulniers, Daniel, Al-Mulla, Fahd, Al-Temaimi, Rabeah, Amedei, Amedeo, Azqueta, Amaya, Bisson, William H., Brown, Dustin, Brunborg, Gunnar, Charles, Amelia K., Chen, Tao, Colacci, Annamaria, Darroudi, Firouz, Forte, Stefano, Gonzalez, Laetitia, A.Hamid, Roslida

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Human immunodeficiency virus infection and cancer by Newton, R, Beral, V, Weiss, R

“…Infectious agents are a significant and theoretically preventable cause of cancer. Therefore, the identification of additional cancers with an infectious aetiology has important public health implications. …”

Adult leydig cell tumors of the testis caused by germline fumarate hydratase mutations. by Carvajal-Carmona, L, Alam, N, Pollard, P, Jones, A, Barclay, E, Wortham, N, Pignatelli, M, Freeman, A, Pomplun, S, Ellis, I, Poulsom, R, El-Bahrawy, M, Berney, D, Tomlinson, I

“…We identified an LCT in an affected individual from a kindred with hereditary leiomyomatosis and renal cell cancer (HLRCC) and a germline fumarate hydratase (FH) mutation (N64T). …”

MMP13 mutation causes spondyloepimetaphyseal dysplasia, Missouri type (SEMD(MO). by Kennedy, A, Inada, M, Krane, S, Christie, P, Harding, B, López-Otín, C, Sánchez, L, Pannett, A, Dearlove, A, Hartley, C, Byrne, M, Reed, A, Nesbit, M, Whyte, M, Thakker, R

“…MMPs, which degrade components of the ECM, have roles in embryonic development, tissue repair, cancer, arthritis, and cardiovascular disease. We show that a missense mutation of MMP13 causes the Missouri type of human spondyloepimetaphyseal dysplasia (SEMD(MO)), an autosomal dominant disorder characterized by defective growth and modeling of vertebrae and long bones. …”

TREATING BONE CANCER AT THE EARLY STAGE by MPRC, Pusat Media & Perhubungan Awam

“…KUBANG KERIAN, July 2016 Cancer is a dreadful disease which might cause death, but can be treated in several ways such as chemotherapy, radiotherapy or surgery and taking medications.…”
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Inborn and acquired metabolic defects in cancer. by Frezza, C, Pollard, P, Gottlieb, E

“…The observation that altered metabolism is the fundamental cause of cancer was made by Otto Warburg nearly a century ago. …”

The evidence base for breast cancer screening. by Glasziou, P, Houssami, N

“…However, given that 4% of all-cause mortality is due to breast cancer deaths, this translates into a less than 1% reduction in all-cause mortality. …”

Tumour markers help detect cancer by Abd Razak, Dzulkifli

“…Cancer is said to be the second leading cause of deaths in Malaysia and it is estimated that 40,000 cases are diagnosed yearly. …”
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Prostate cancer: pathophysiology, diagnosis, and prognosis by Falah Abass Mohamed Salih, Murtaza Mustafa, EM.Illzam, AM.Sharifa, M.Suleiman, SS.Hussain

“…Prostate cancer is more common in the western countries, least common in Asia, and the leading cause of cancer deaths in males worldwide. …”
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Comparison of cancer incidence trend in Asia. by Lee, Hsueh Heng., Teoh, Ying Ying., Low, Jun Jack.

“…According to GLOBOCAN, cancer is the leading cause of disease worldwide. …”
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Exploiting epigenetic vulnerabilities for cancer therapeutics. by Mair, B, Kubicek, S, Nijman, S

“…An alternative incentive for targeting chromatin regulators is the exploitation of cancer-specific vulnerabilities, including synthetic lethality, caused by epigenetic deregulation. …”