Exercise during chemotherapy to prevent breast cancer-related cognitive decline: protocol for a pilot randomized controlled trial by Elizabeth A. Salerno, Elizabeth A. Salerno, Courtney Harriss, D. Carolina Andrade, Lindsay L. Peterson, Lindsay L. Peterson, Ryan P. Duncan, Maura M. Kepper, Jingqin Luo, Jingqin Luo, Patricia Creel, Graham A. Colditz, Graham A. Colditz

“…The purpose of this study is to pilot test a home-based prehabilitation physical activity intervention aimed at preventing cognitive decline during chemotherapy, as well as assess the feasibility, acceptability and appropriateness of the intervention among patients.MethodsThis study is a two-arm, pilot randomized controlled trial in 40 adult patients newly diagnosed with breast cancer stages I-III who are scheduled to receive curative intent neo-adjuvant chemotherapy. …”
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Diagnostic and prognostic role of circulating neutrophil extracellular trap markers and prekallikrein in patients with high-grade serous ovarian cancer by Jisoo G. Kim, Se Ik Kim, Sang Hoon Song, Sang Hoon Song, Ja-Yoon Gu, Ja-Yoon Gu, Maria Lee, Maria Lee, Hyun Kyung Kim, Hyun Kyung Kim, Hyun Kyung Kim

“…Further, the levels of histone-DNA complex, neutrophil elastase, and prekallikrein did not significantly differ according to the cancer stage. All markers showed significant diagnostic utility. …”
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Lenvatinib plus anti-PD-1 therapy represents a feasible conversion resection strategy for patients with initially unresectable hepatocellular carcinoma: A retrospective study by Yong Yi, Bao-Ye Sun, Jia-Lei Weng, Cheng Zhou, Chen-Hao Zhou, Ming-Hao Cai, Jing-Yun Zhang, Hong Gao, Jian Sun, Jian Zhou, Jia Fan, Ning Ren, Ning Ren, Shuang-Jian Qiu

“…At baseline, the median largest tumor diameter of these 30 patients was 9.2 cm (range: 3.5-15.0 cm), 26 patients had Barcelona Clinic Liver Cancer stage B-C, and 4 had stage A. Prior to surgery, all cases displayed tumor regression and 15 patients achieved objective response. …”
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Uniportal versus multiportal nonintubated thoracoscopic anatomical resection for lung cancer: A propensity-matched analysis by Jen-Hao Chuang, Pei-Hsing Chen, Tzu-Pin Lu, Wan-Ting Hung, Hsien-Chi Liao, Tung-Ming Tsai, Mong-Wei Lin, Ke-Cheng Chen, Hsao-Hsun Hsu, Jin-Shing Chen

“…Propensity scores were matched according to age, sex, body mass index, pulmonary function, tumor size, cancer stage, and surgical method. Results: In total, 1130 such patients underwent nonintubated video-assisted thoracoscopic surgery (VATS), and 490 consecutive patients with stage I–III NSCLC underwent nonintubated anatomical resection, including lobectomy and segmentectomy (uniportal, n = 158 [32.3%]; multiportal, n = 331 [67.7%]). …”
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Data mining-based study of collagen type III alpha 1 (COL3A1) prognostic value and immune exploration in pan-cancer by Hanyu Zhang, Cheng Ding, Yatong Li, Cheng Xing, Shunda Wang, Zhangping Yu, Lixin Chen, Pengyu Li, Menghua Dai

“…Upregulation of COL3A1 is associated with a worse prognosis and a more advanced cancer stage. COL3A1 expression shows significant positive correlations with tumor-infiltrating immune cells (TIICs), including neutrophils, macrophages, CD8 + T cells, CD4 + T cells, dendritic cells, and B cells. …”
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The Plasma DIA-Based Quantitative Proteomics Reveals the Pathogenic Pathways and New Biomarkers in Cervical Cancer and High Grade Squamous Intraepithelial Lesion by Sai Han, Junhua Zhang, Yu Sun, Lu Liu, Lingyu Guo, Chunru Zhao, Jiaxin Zhang, Qiuhong Qian, Baoxia Cui, Youzhong Zhang

“…Subsequently, the WGCNA analysis showed that the green module was highly correlated with the cervical cancer stage. Additionally, six interesting core DEPs were verified by ELISA, APOF and ORM1, showing nearly the same expression pattern with DIA. …”
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The Impact of COVID-19 Pandemic on Surgical Treatment of Resectable Non-Small Cell Lung Cancer in Greece by Ioannis Tomos, Emmanouil I. Kapetanakis, Konstantina Dimakopoulou, Thomas Raptakis, Katerina Kampoli, Anna Karakatsani, Anna Koumarianou, Spyros Papiris, Periklis Tomos

“…Waiting time to surgical treatment, increase of tumor’s size and increase on lung cancer stage were recorded and compared. All subjects were followed up for 12 months. …”
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Cancer Risk Following HLA-Incompatible Living Donor Kidney Transplantation by Jennifer D. Motter, MHS, Allan B. Massie, PhD, Jacqueline M. Garonzik-Wang, MD, PhD, Ruth M. Pfeiffer, PhD, Kelly J. Yu, PhD, Dorry L. Segev, MD, PhD, Eric A. Engels, MD, MPH

“…Cancer risk did not vary according to donor-specific antibody strength, and in an exploratory analysis, was similar between CLDKTr and ILDKTr for most cancer types and according to cancer stage, except ILDKTr had a suggestively increased risk of colorectal cancer (wHR 3.27; 95% CI, 1.23-8.71); however, this elevation was not significant after correction for multiple comparisons. …”
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Alpha-Fetoprotein Combined with Radiographic Tumor Burden Score to Predict Overall Survival after Liver Resection in Hepatocellular Carcinoma by Yi-Hao Yen, Yueh-Wei Liu, Wei-Feng Li, Chih-Chi Wang, Chee-Chien Yong, Chih-Che Lin, Chih-Yun Lin

“…Patients who underwent LR for Barcelona Clinic Liver Cancer stage 0, A, or B HCC between 2011 and 2018 were enrolled. …”
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Identification of Skin Tumours using Statistical and Histogram Based Features by TR Thamizhvani, RJ Hemalatha, Bincy Babu, A Josephin Arockia Dhivya, Josline Elsa Joseph, R Chandrasekaran

“…The rate of survival depends on the cancer stages, if diagnosed early it can be treated completely. …”
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Direct inhibition of ACTN4 by ellagic acid limits breast cancer metastasis via regulation of β-catenin stabilization in cancer stem cells by Neng Wang, Qi Wang, Hailin Tang, Fengxue Zhang, Yifeng Zheng, Shengqi Wang, Jin Zhang, Zhiyu Wang, Xiaoming Xie

“…Increased ACTN4 expression was directly associated with the advanced cancer stage, an increased incidence of metastasis, and poor overall survival period. …”
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Gut Microbiome of Patients With Breast Cancer in Vietnam by Sang M. Nguyen, Huong T.T. Tran, Jirong Long, Martha J. Shrubsole, Hui Cai, Yaohua Yang, Lan M. Nguyen, Giang H. Nguyen, Chu V. Nguyen, To V. Ta, Jie Wu, Qiuyin Cai, Wei Zheng, Thuan V. Tran, Xiao-Ou Shu

“…We did not find that cancer stage and subtype, menopausal status, comorbidity, antibiotic use during 3 months before stool collection, or physical activity was significantly associated with α- and β-diversities or GMHI although a few significant differences were observed in taxa abundance.CONCLUSIONOur study revealed that diagnosis delay, high fiber intake, and breast cancer surgery, which is always followed by antibiotic prophylaxis in Vietnam, led to a less diverse and unhealthy gut microbiome among patients with breast cancer.…”
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Protocol for a pragmatic cluster randomised controlled trial assessing the clinical effectiveness and cost-effectiveness of Electronic RIsk-assessment for CAncer for patients in ge... by Gary A Abel, John L Campbell, Martin Pitt, Sarah Gerard Dean, Luke Mounce, Fiona C Warren, Emily Fletcher, Anne Spencer, Raff Calitri, Antonieta Medina-Lara, Elizabeth Shephard, Marijke Shakespeare, Adrian Mercer

“…The primary outcome is cancer stage at diagnosis, dichotomised to stage 1 or 2 (early) or stage 3 or 4 (advanced) for these six cancers, assessed from National Cancer Registry data. …”
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Concomitant preoperative airflow obstruction confers worse prognosis after trans-thoracic surgery for esophageal cancer by Ke Lang, Xiaocen Wang, Tingting Wei, Zhaolin Gu, Yansha Song, Dong Yang, Dong Yang, Hao Wang

“…A subgroup analysis revealed that the above results were more significant in male patients, BMI < 23 kg/m2 patients or late-stage cancer (stage III-IVA) (P = 0.001) patients and those undergoing open esophagectomy (P < 0.001).ConclusionPreoperative airflow obstruction defined by FEV1/FVC ratio below LLN was an independent risk factor for mortality in esophageal cancer patients after trans-thoracic esophagectomy. …”
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A nomogram prediction model for lymph node metastasis risk after neoadjuvant chemoradiotherapy in rectal cancer patients based on SEER database by Xiaoshuang Liu, Xiaoshuang Liu, Li Sha, Cheng Huang, Xiancheng Kong, Feihu Yan, Xiaohui Shi, Xuefeng Tang

“…BackgroundRectal cancer patients who received neoadjuvant chemoradiotherapy (CRT) may have a lower cancer stage and a better prognosis. Some patients may be able to avoid invasive surgery. …”
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Incidence and survival of gynecologic cancer including cervical, uterine, ovarian, vaginal, vulvar cancer and gestational trophoblastic neoplasia in Korea, 1999–2019: Korea Central... by Bo Seong Yun, Eun Hye Park, Johyun Ha, Jung-Yun Lee, Keun Ho Lee, Taek Sang Lee, Kyung Ju Lee, Young Ju Kim, Kyu-Won Jung, Ju-Won Roh

“…For all gynecologic cancer types, the prognosis deteriorates with advancing cancer stages. The RSR of uterine cancer improved consistently across all periods. …”
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DNA methylation biomarkers distinguishing early-stage prostate cancer from benign prostatic hyperplasia by Stephanie S. Kim, Seung Cho Lee, Bumjin Lim, Seung-Ho Shin, Mee Young Kim, Sol-Yi Kim, Hyeyeun Lim, Clémentine Charton, Dongho Shin, Hyong Woo Moon, Jinho Kim, Donghyun Park, Woong-Yang Park, Ji Youl Lee

“…This suggests that dissecting early-to-advanced-grade cancer stages requires an in-depth analysis of differential methylation at the single CpG site level. …”
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FOXM1 increases hTERT protein stability and indicates poor prognosis in gastric cancer by Qingyun Tang, Cheng Liu, Shengwei Zhang, Lijiao He, Yunyi Liu, Jing Wang, Xiaoyan Zhao, Xinzhe Li

“…In our study, we found that FOXM1 and hTERT were convergent to the cell cycle-related pathways and they were positively related with advanced gastric cancer stages and poor outcomes. Simultaneous high levels of FOXM1 and hTERT predicted the worst prognosis. …”
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Clinical utility and diagnostic value of tumor-educated platelets in lung cancer: a systematic review and meta-analysis by Elvan Wiyarta, Darrin Ananda Nugraha, Muhammad Indera Ramadani, Gita Fajri Gustya, Muhammad Farrasy Ammar, Hana Dzakira Edwar, Nildza Kheirizzad, Mutiah Nurul Mukhlisah, Erlina Burhan, Elisna Syahruddin

“…Heterogeneity may result from cancer stage, cancer control, measuring equipment, and RNA types across studies. …”
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Factors Associated with Long-Term Dietary Supplement Use among Korean Breast Cancer Survivors: A Cross-Sectional Study by Seonghye Kim, Yohwan Yeo, Jinyoung Shin, Dong Wook Shin, Belong Cho, Yun-Mi Song

“…Among DS users, as compared with short-term (≥2 weeks and <6 months) users, long-term users were more likely to have a higher cancer stage, more diverse cancer treatment modalities, a shorter time since cancer diagnosis, and lower fear of cancer recurrence. …”
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