Community Programs to Control Cancer of The Cervix by Antônio Prudente

“…Mass examination is able to change the general picture of cancer stages at the time of diagnosis. The kind of organization which carries out the detection of cervix cancer does not matter very much. …”
Get full text

Stem-Like Signature Predicting Disease Progression in Early Stage Bladder Cancer. The Role of E2F3 and SOX4 by Joaquim Bellmunt

“…SOX4 gene expression correlates with advanced cancer stages and poor survival rate in bladder cancer, supporting a potential role as a regulator of the bladder CSC properties. …”
Get full text

Health Indicators as Measures of Individual Health Status and Their Public Perspectives: Cross-sectional Survey Study by Temiloluwa Sokoya, Yuchun Zhou, Sebastian Diaz, Timothy Law, Lina Himawan, Francisca Lekey, Lu Shi, Ronald W Gimbel, Xia Jing

“… BackgroundDisease status (eg, cancer stage) has been used in routine clinical practice to determine more accurate treatment plans. …”
Get full text

The prognostic value and immunological role of SULF2 in adrenocortical carcinoma by Jiusong Yan, Xiaodu Xie, Qinke Li, Peihe Liang, Junyong Zhang, Guangyong Xu

“…Finally, R package was utilized to plot the receiver operating characteristic (ROC) curves of diagnosis, time-dependent survival, and the association of SULF2 with cancer stage and the nomogram model. Finally, CellMiner dataset was adopted for SULF2 correlation as well as drug sensitivity analysis. …”
Get full text

Development and internal-external validation of statistical and machine learning models for breast cancer prognostication: cohort study by Clift, AK, Dodwell, D, Lord, S, Petrou, S, Brady, M, Collins, GS, Hippisley-Cox, J

“…Predictors varied for each regression model, but both Cox and competing risks models included age at diagnosis, body mass index, smoking status, route to diagnosis, hormone receptor status, cancer stage, and grade of breast cancer. The Cox model’s random effects meta-analysis pooled estimate for Harrell’s C index was the highest of any model at 0.858 (95% confidence interval 0.853 to 0.864, and 95% prediction interval 0.843 to 0.873). …”

Sociodemographic characteristics, clinicopathological parameters and survival among Malaysians with oral squamous cell carcinoma (OSCC) by Ghani, W.M.N., Zain, R.B., Jalil, N., Razak, I.A., Raja-Latifah, Raja Jallaludin, Samsuddin, A.R.

“…A highly significant association was seen for both cancer stage and nodal involvement with survival. More survivors were found among those who come at early stage (76.3%) compared to late stage (32.7%). …”
Get full text
Get full text

Relationships between Wnt-Notch-Hippo signaling pathways and their relevance to colorectal cancer pathogenesis by Chai, Boon Lee

“…Biomolecule expression was associated with various pathological parameters using 2 test. Cancer stage was significantly associated with expression of nuclear β-catenin (p=0.013), Notch1 (p=0.005), NICD1 (p=0.011) and nuclear YAP (p=0.001), histological grade was significantly associated with expression of cytoplasmic β-catenin (p=0.013), membranous β-catenin (p=0.020) and PMS2 (p=0.014). …”
Get full text

The Outcomes of Esophageal and Gastric Cancer Treatments in a Retrospective Study, Single Center Experience by Kamran Alimoghaddam, Arash Jalali, Leyla Sharifi Aliabadi, Fatemeh Ghaffari, Roghieh Maheri, Ezzat Eini, Maryam Mashhadireza, Seied Asadollah Mousavi, Babak Bahar, Mohammad Jahani, Ardeshir Ghavamzadeh

“…Methods: In this retrospective study, we reviewed the data of patient's files before treatment, including cancer stage at diagnosis, types of treatments and outcomes. …”
Get full text

Effects of walking football on adherence, safety, quality of life and physical fitness in patients with prostate cancer: Findings from the PROSTATA_MOVE randomized controlled trial by Andreia Capela, Andreia Capela, Pedro Antunes, Pedro Antunes, César André Coelho, Catarina Laranjeiro Garcia, Catarina Laranjeiro Garcia, Sandra Custódio, Sandra Custódio, Rui Amorim, Telma Costa, Telma Costa, Eduardo Vilela, Madalena Teixeira, Anabela Amarelo, Anabela Amarelo, Joana Silva, Joana Silva, Ana Joaquim, Ana Joaquim, Sofia Viamonte, Sofia Viamonte, João Brito, Alberto J. Alves, Alberto J. Alves

“…AimsTo analyze the feasibility and impact of a walking football (WF) program on quality of life (QoL), cardiorespiratory fitness (CRF), muscle strength, and balance program in men with prostate cancer under androgen deprivation therapy (ADT).MethodsFifty patients with prostate cancer (stages IIb-IVb) under ADT were randomized to a 16-week WF program plus usual care (n=25) or usual care control group (n=25). …”
Get full text

KLF2 is a clinical diagnostic and treatment biomarker of breast cancer by Ya-Zhao Li, Ya-Zhao Li, Juan Xie, Rui-Qi Wang, Rui-Qi Wang, Xiao-Qian Gao, Xiao-Qian Gao, Pei-Jun Liu, Pei-Jun Liu, Jie Liu, Jie Liu

“…KLF2 expression levels were found to be reduced in advanced cancer stages and grades, while positively correlated with the expression of estrogen receptor (ER), progesterone receptor (PR), and tumor size in breast cancer. …”
Get full text

Impact of the COVID‐19 pandemic on clinical presentation, treatments, and outcomes of new breast cancer patients: A retrospective multicenter cohort study by Etienne Guével, Sonia Priou, Guillaume Lamé, Johanna Wassermann, Romain Bey, Catherine Uzan, Gilles Chatellier, Yazid Belkacemi, Xavier Tannier, Sophie Guillerm, Rémi Flicoteaux, Joseph Gligorov, Ariel Cohen, Marc‐Antoine Benderra, Luis Teixeira, Christel Daniel, Barbara Hersant, Christophe Tournigand, Emmanuelle Kempf, the Assistance Publique–Hôpitaux de Paris (AP‐HP) Cancer Group, a Cancer Research Application on Big Data (CRAB) initiative

“…Abstract Background The SARS CoV‐2 pandemic disrupted healthcare systems. We compared the cancer stage for new breast cancers (BCs) before and during the pandemic. …”
Get full text

Survival effect of pre-RT PET-CT on cervical cancer: Image-guided intensity-modulated radiation therapy era by Chih-Hsiung Su, Wan-Ming Chen, Wan-Ming Chen, Mingchih Chen, Ben-Chang Shia, Ben-Chang Shia, Szu-Yuan Wu, Szu-Yuan Wu, Szu-Yuan Wu, Szu-Yuan Wu, Szu-Yuan Wu, Szu-Yuan Wu, Szu-Yuan Wu, Szu-Yuan Wu, Szu-Yuan Wu

“…Regardless of the cancer stage (early or advanced), pretreatment PET–CT was significantly superior to nonpretreatment PET–CT in terms of all-cause death (aHR, 0.78; 95% CI, 0.60–0.92; P = 0.013 and aHR, 0.90; 95% CI, 0.81–0.99; P = 0.039 for the early [IB–IIA] and advanced stages [IIB–IVA], respectively).ConclusionsPretreatment 18FDG-PET–CT might be associated with longer survival in patients with stage IB–IVA cervical cancer receiving RT or CCRT, especially in the era of IG-IMRT.…”
Get full text

Pyroptosis relates to tumor microenvironment remodeling and prognosis: A pan-cancer perspective by Muhammad Khan, Muhammad Khan, Meiling Ai, Meiling Ai, Kunpeng Du, Kunpeng Du, Jingjing Song, Baiyao Wang, Baiyao Wang, Jie Lin, Jie Lin, Anbang Ren, Anbang Ren, Chengcong Chen, Chengcong Chen, Zhong Huang, Zhong Huang, Wenze Qiu, Wenze Qiu, Jiangyu Zhang, Yunhong Tian, Yunhong Tian, Yawei Yuan, Yawei Yuan

“…Pyroptosis level significantly differentiated tumor from normal samples in 15 types of cancers, exhibited a progressive trend with cancer stage, observed variation among cancer subtypes, and showed a significant association with cancer prognosis. …”
Get full text

Predicting prostate cancer progression with a Multi-lncRNA expression-based risk score and nomogram integrating ISUP grading by Sabrina Ledesma-Bazan, Florencia Cascardo, Juan Bizzotto, Santiago Olszevicki, Elba Vazquez, Geraldine Gueron, Javier Cotignola

“…We performed bioinformatics analyses to identify lncRNAs differentially expressed across various prostate cancer stages and associated with progression-free survival. …”
Get full text

The impact of the UK COVID-19 lockdown on the screening, diagnostics and incidence of breast, colorectal, lung and prostate cancer in the UK: a population-based cohort study by Nicola L. Barclay, Marta Pineda Moncusí, Annika M. Jödicke, Daniel Prieto-Alhambra, Daniel Prieto-Alhambra, Berta Raventós, Danielle Newby, Antonella Delmestri, Wai Yi Man, Xihang Chen, Marti Català

“…Delays in diagnosis are likely to have adverse consequences on cancer stage, treatment initiation, mortality rates, and years of life lost. …”
Get full text

Analysis of Immune-Related Adverse Events of Atezolizumab and Bevacizumab in Patients with Hepatocellular Carcinoma: A Multicentre Cohort Study by Heechul Nam, Jaejun Lee, Ji Won Han, Soon Kyu Lee, Hyun Yang, Hae Lim Lee, Pil Soo Sung, Hee Yeon Kim, Seok-Hwan Kim, Myeong Jun Song, Jung-Hyun Kwon, Chang Wook Kim, Soon Woo Nam, Si Hyun Bae, Jong Young Choi, Seung Kew Yoon, Jeong Won Jang

“…Among them, 93.3% of patients were classified as Barcelona Clinic Liver Cancer stage C, 52.0% had portal vein tumour thrombosis (PVTT), and 60.7% extrahepatic spread. …”
Get full text

Personalized Prescription of Chemotherapy Based on Assessment of mRNA Expression of <i>BRCA1, RRM1, ERCC1, TOP1, TOP2α, TUBβ3</i>, <i>TYMS</i>, and <i>GSTP1</i> Genes in Tumors Com... by Matvey M. Tsyganov, Evgeny O. Rodionov, Marina K. Ibragimova, Sergey V. Miller, Olga V. Cheremisina, Irina G. Frolova, Sergey A. Tuzikov, Nikolai V. Litviakov

“…Materials and methods: The present study analyzed 85 patients with lung cancer (stage IIB-IIIB). Within this group, 48 patients received individualized chemotherapy, and 37 patients received classical chemotherapy. …”
Get full text

Conversion surgery for stage IV gastric cancer: a multicenter retrospective study by Yosuke Kano, Hiroshi Ichikawa, Takaaki Hanyu, Yusuke Muneoka, Takashi Ishikawa, Masaki Aizawa, Atsushi Matsuki, Hiroshi Yabusaki, Takeo Bamba, Satoru Nakagawa, Kazuaki Kobayashi, Shirou Kuwabara, Shigeto Makino, Yasuyuki Kawachi, Tetsuya Naito, Tatsuo Tani, Hiroshi Hirukawa, Tetsuya Tada, Yoshifumi Shimada, Jun Sakata, Toshifumi Wakai

Get full text

Identification and validation of an epithelial mesenchymal transition-related gene pairs signature for prediction of overall survival in patients with skin cutaneous melanoma by Yucang Shi, Zhanpeng Li, Zhihong Zhou, Simu Liao, Zhiyuan Wu, Jie Li, Jiasheng Yin, Meng Wang, Meilan Weng

“…Most importantly, the decision curve analysis results showed that the nomogram had a higher net benefit than that of the American Joint Committee on Cancer stage system. Conclusion Our study established an ERGPs signature that could be potentially used in a clinical setting as a genetic biomarker for risk stratification of CM patients. …”
Get full text

A study on correlation of acetyltransferase KAT3b and ABCE1 acetylation in esophageal cancer by LIANG Zongying, YANG Yang, SUN Guangrui, ZHAO Baoshan, XIN Guohua, ZHANG Le, HOU Jishen

“…ABCE1 acetylation and KAT3b were associated with esophageal cancer stage, tissue differentiation and lymph node metastasis, and were independent of gender and age. …”
Get full text